List of works by Jeff Holst

A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth

scientific article published in 2021

ASCT2 regulates glutamine uptake and cell growth in endometrial carcinoma

scientific article

ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer.

scientific article published on 12 October 2015

ASCT2: a potential cancer drug target

scientific article published on 04 June 2019

Ablation of the ASCT2 (SLC1A5) gene encoding a neutral amino acid transporter reveals transporter plasticity and redundancy in cancer cells

scientific article published on 11 January 2019

Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration

scientific article published on 13 January 2017

Amino Acid Transporters and Exchangers from the SLC1A Family: Structure, Mechanism and Roles in Physiology and Cancer

scientific article published on 24 January 2020

Androgen receptor and nutrient signaling pathways coordinate the demand for increased amino acid transport during prostate cancer progression.

scientific article published on 17 October 2011

Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways.

scientific article

Bioactive Dihydro-β-agarofuran Sesquiterpenoids from the Australian Rainforest Plant Maytenus bilocularis

scientific article published on 27 April 2016

Celastrofurans A-G: Dihydro-β-agarofurans from the Australian Rainforest Vine Celastrus subspicata and Their Inhibitory Effect on Leucine Transport in Prostate Cancer Cells

scientific article

Changes in CpG methylation marks differentiation of human myeloid progenitors to neutrophils.

scientific article published on 27 May 2014

DNA methylation/hydroxymethylation regulate gene expression and alternative splicing during terminal granulopoiesis

scientific article published on 14 November 2018

Dihydro-β -agarofurans from the Australian Endemic Rainforest Plant Denhamia pittosporoides Inhibit Leucine Transport in Prostate Cancer Cells

article

Dihydro-β-agarofurans from the Australian rainforest plant Denhamia celastroides that inhibit leucine transport in prostate cancer cells

article

Dihydro-β-agarofurans from the roots of the Australian endemic rainforest tree Maytenus bilocularis act as leucine transport inhibitors.

scientific article published on 30 January 2018

Distinct Immune Cell Populations Define Response to Anti-PD-1 Monotherapy and Anti-PD-1/Anti-CTLA-4 Combined Therapy

scientific article published on 01 February 2019

Distinct Molecular Profiles and Immunotherapy Treatment Outcomes of V600E and V600K BRAF-Mutant Melanoma

scientific article published on 10 January 2019

Extracellular Fatty Acids Are the Major Contributor to Lipid Synthesis in Prostate Cancer

scientific article published on 15 January 2019

General nature of the STAT3-activated anti-inflammatory response.

scientific article

Glutamine addiction promotes glucose oxidation in triple-negative breast cancer

scientific article published on 18 July 2022

Guttiferone K impedes cell cycle re-entry of quiescent prostate cancer cells via stabilization of FBXW7 and subsequent c-MYC degradation

scientific article published on 02 June 2016

Heritable expansion of the genetic code in mouse and zebrafish

scientific article

Homology Modeling Informs Ligand Discovery for the Glutamine Transporter ASCT2

scientific article published on 24 July 2018

Identification of nuclear-enriched miRNAs during mouse granulopoiesis

scientific article

Identifying microRNA determinants of human myelopoiesis.

scientific article

Intron retention is regulated by altered MeCP2-mediated splicing factor recruitment.

scientific article

L-type amino acid transport and cancer: targeting the mTORC1 pathway to inhibit neoplasia

scientific article published on 15 March 2015

LAT Transport Inhibitors from Pittosporum venulosum Identified by NMR Fingerprint Analysis ⬇️

scientific article published on 18 May 2015

LAT1 is a putative therapeutic target in endometrioid endometrial carcinoma

scientific article published on 3 August 2016

Ligand Discovery for the Alanine-Serine-Cysteine Transporter (ASCT2, SLC1A5) from Homology Modeling and Virtual Screening

scientific article

Luciferase expression and bioluminescence does not affect tumor cell growth in vitro or in vivo

scientific article

Micro-RNA response to imatinib mesylate in patients with chronic myeloid leukemia

scientific article

Monoterpene glycoside ESK246 from Pittosporum targets LAT3 amino acid transport and prostate cancer cell growth.

scientific article

Nuclear-localized tiny RNAs are associated with transcription initiation and splice sites in metazoans.

scientific article published on 11 July 2010

Orchestrated intron retention regulates normal granulocyte differentiation.

scientific article published in August 2013

Performance evaluation of the Abbott CELL-DYN Emerald for use as a bench-top analyzer in a research setting

scientific article published on 27 December 2012

Protein phosphatase 2A carboxymethylation and regulatory B subunits differentially regulate mast cell degranulation

scientific article published on 2 August 2010

Protein phosphatase translocation in RBL-2H3 cells

scientific article published on 01 January 2003

Protein phosphatases 1 and 2A transiently associate with myosin during the peak rate of secretion from mast cells

scientific article

RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes

scientific article published on 03 January 2019

RB/E2F1 as a Master Regulator of Cancer Cell Metabolism in Advanced Disease

publication published on 20 April 2021

RBM3 regulates temperature sensitive miR-142-5p and miR-143 (thermomiRs), which target immune genes and control fever

scientific article published on 28 January 2016

Rapid analysis of T-cell selection in vivo using T cell-receptor retrogenic mice.

scientific article

Regulation of SLC1A4 and SLC1A5 in Prostate Cancer-Letter

scientific article published on 01 November 2018

Renal imino acid and glycine transport system ontogeny and involvement in developmental iminoglycinuria.

scientific article published on 27 May 2010

SAMHD1 enhances immunoglobulin hypermutation by promoting transversion mutation.

scientific article published on 18 April 2018

Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity

scientific article published on 11 May 2008

Stromal androgen receptor regulates the composition of the microenvironment to influence prostate cancer outcome.

scientific article

Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells

scientific article published on 3 October 2010

T-cell acute lymphoblastic leukemias express a unique truncated FAT1 isoform that cooperates with NOTCH1 in leukemia development

scientific article published on 04 December 2018

Targeting ASCT2-mediated glutamine uptake blocks prostate cancer growth and tumour development

scientific article

Targeting Vascular Endothelial-Cadherin in Tumor-Associated Blood Vessels Promotes T-cell-Mediated Immunotherapy

scientific article published on 27 June 2017

Targeting amino acid transport in metastatic castration-resistant prostate cancer: effects on cell cycle, cell growth, and tumor development.

scientific article

Targeting glutamine transport to suppress melanoma cell growth.

scientific article published on 17 February 2014

Targeting of cytosolic phospholipase A2α impedes cell cycle re-entry of quiescent prostate cancer cells

scientific article published on 24 September 2015

The Fat1 cadherin is overexpressed and an independent prognostic factor for survival in paired diagnosis-relapse samples of precursor B-cell acute lymphoblastic leukemia

scientific article

The antiproliferative ELF2 isoform, ELF2B, induces apoptosis in vitro and perturbs early lymphocytic development in vivo

scientific article published on 28 March 2017

The cancer-testis antigen BORIS phenocopies the tumor suppressor CTCF in normal and neoplastic cells.

scientific article published on 2 May 2013

The role of serine/threonine protein phosphatases in exocytosis

scientific article

Tonic ubiquitylation controls T-cell receptor:CD3 complex expression during T-cell development

scientific article

Transient translocation and activation of protein phosphatase 2A during mast cell secretion

scientific article

Tumour-specific CD4 T cells eradicate melanoma via indirect recognition of tumour-derived antigen

scientific article published on 03 February 2016

p27(Kip1) signaling: Transcriptional and post-translational regulation.

scientific article published on 13 August 2015

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