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List of works by Margot Thome

Activating mutations in genes related to TCR signaling in angioimmunoblastic and other follicular helper T-cell-derived lymphomas.

scientific article

Anti-apoptotic strategies of lymphotropic viruses

scientific article published on 01 October 1998

Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis

scientific article published on September 2002

Bcl10

scientific article published on 01 January 2002

CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-kappa B activation

scientific article

CARMA1, BCL-10 and MALT1 in lymphocyte development and activation.

scientific article published on May 2004

CARMA1- and MyD88-dependent activation of Jun/ATF-type AP-1 complexes is a hallmark of ABC diffuse large B-cell lymphomas.

scientific article published on 8 January 2016

Carma1, a CARD-containing binding partner of Bcl10, induces Bcl10 phosphorylation and NF-kappaB activation

scientific article (publication date: 11 May 2001)

Caspase-8 and c-FLIPL associate in lipid rafts with NF-kappaB adaptors during T cell activation.

scientific article published on 26 April 2007

Caspase-mediated cleavage of raptor participates in the inactivation of mTORC1 during cell death

scientific article published on 18 April 2016

Cathepsin X cleavage of the beta2 integrin regulates talin-binding and LFA-1 affinity in T cells

scientific article published on 31 March 2011

Characterization of two receptors for TRAIL1 ⬇️

scientific article published on October 27, 1997

Detection and measurement of paracaspase MALT1 activity

scientific article published on 01 January 2014

Dlgh1 and Carma1 MAGUK proteins contribute to signal specificity downstream of TCR activation.

scientific article published on 28 March 2007

Equine herpesvirus protein E10 induces membrane recruitment and phosphorylation of its cellular homologue, bcl-10

scientific journal article

Equine herpesvirus-2 E10 gene product, but not its cellular homologue, activates NF-kappaB transcription factor and c-Jun N-terminal kinase

scientific journal article

Essential role of MALT1 protease activity in activated B cell-like diffuse large B-cell lymphoma.

scientific article

Evidence for a TCR affinity threshold delimiting maximal CD8 T cell function.

scientific article published on 29 March 2010

IKKα takes control of canonical NF-κB activation.

scientific article

Identification of CARDIAK, a RIP-like kinase that associates with caspase-1 ⬇️

scientific article published on July 16, 1998

Individual caspase-10 isoforms play distinct and opposing roles in the initiation of death receptor-mediated tumour cell apoptosis. ⬇️

scientific article published on 3 March 2011

Inhibition of fas death signals by FLIPs

scientific article published on 01 October 1998

MALT1 auto-proteolysis is essential for NF-κB-dependent gene transcription in activated lymphocytes

scientific article

MCL1 is deregulated in subgroups of diffuse large B-cell lymphoma.

scientific article published on 21 December 2012

Malt1-dependent RelB cleavage promotes canonical NF-kappaB activation in lymphocytes and lymphoma cell lines.

scientific article

Molecular cloning of porcine T cell receptor alpha, beta, gamma and delta chains using polymerase chain reaction fragments of the constant regions.

scientific article published on May 1993

Molecular mechanism of T-cell activation: role of protein tyrosine kinases in antigen receptor-mediated signal transduction.

scientific article published on May 1995

Monoubiquitination and activity of the paracaspase MALT1 requires glutamate 549 in the dimerization interface

scientific article

Multifunctional roles for MALT1 in T-cell activation.

scientific article published on July 2008

NOTCH1 Can Initiate NF-κB Activation via Cytosolic Interactions with Components of the T Cell Signalosome

scientific article published on 26 May 2014

PKCθ/β and CYLD are antagonistic partners in the NFκB and NFAT transactivation pathways in primary mouse CD3+ T lymphocytes

scientific article (publication date: 2013)

Phosphorylation of CARMA1 by HPK1 is critical for NF-kappaB activation in T cells

scholarly article

Post-translational modifications regulate distinct functions of CARMA1 and BCL10.

scientific article published on 30 April 2007

RIP4 (DIK/PKK), a novel member of the RIP kinase family, activates NF-kappa B and is processed during apoptosis.

scientific article

Role of the CARMA1/BCL10/MALT1 complex in lymphoid malignancies

scientific article published on 28 April 2016

T cell division and death are segregated by mutation of TCRbeta chain constant domains

scientific article published on 01 October 2004

TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB

scientific article published in December 1997

TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95)

scientific article

Targeting B-cell lymphomas with inhibitors of the MALT1 paracaspase

scientific article published on 04 October 2014

The NF-κB signaling protein Bcl10 regulates actin dynamics by controlling AP1 and OCRL-bearing vesicles

scientific article

The fight of viruses against apoptosis ⬇️

scientific article published on February 1, 1998

The immunological synapse and actin assembly: a regulatory role for PKC theta

scientific article published on 01 January 2003

The p56lck SH2 domain mediates recruitment of CD8/p56lck to the activated T cell receptor/CD3/zeta complex.

scientific article published on September 1996

The paracaspase MALT1: biological function and potential for therapeutic inhibition

scientific article

The protease activity of the paracaspase MALT1 is controlled by monoubiquitination.

scientific article published on 17 February 2013

Viral inhibitor of apoptosis vFLIP/K13 protects endothelial cells against superoxide-induced cell death.

scientific article

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