List of works - Megan L. Shaw

A Potent Anti-influenza Compound Blocks Fusion through Stabilization of the Prefusion Conformation of the Hemagglutinin Protein

scientific article

A Sendai virus-derived RNA agonist of RIG-I as a virus vaccine adjuvant.

scientific article

A novel small molecule inhibitor of influenza A viruses that targets polymerase function and indirectly induces interferon

scientific article

An Influenza Virus Entry Inhibitor Targets Class II PI3 Kinase and Synergizes with Oseltamivir

scientific article published on 09 September 2019

Author Correction: SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses.

scientific article

Broad Spectrum Inhibitor of Influenza A and B Viruses Targeting the Viral Nucleoprotein.

scientific article published on 21 December 2017

Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis

scientific article

Cellular proteins in influenza virus particles

scientific article

Characterisation of the differences between hepatitis C virus genotype 3 and 1 glycoproteins.

scientific article published on July 2003

Ebola virus VP24 binds karyopherin alpha1 and blocks STAT1 nuclear accumulation

scientific article

Frequency, kinetics and determinants of viable SARS-CoV-2 in bioaerosols from ambulatory COVID-19 patients infected with the Beta, Delta or Omicron variants

scientific article published on 5 March 2024

Henipaviruses Employ a Multifaceted Approach to Evade the Antiviral Interferon Response ⬇️

scientific article published on December 8, 2009

High-Throughput Minigenome System for Identifying Small-Molecule Inhibitors of Ebola Virus Replication

scientific article published on August 2015

Human host factors required for influenza virus replication

scientific article

Identification of small molecules with type I interferon inducing properties by high-throughput screening

scientific article

Influenza

Inhibition of arenavirus by A3, a pyrimidine biosynthesis inhibitor.

scientific article published on 6 November 2013

Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding.

scientific article

Modulation of influenza virus replication by alteration of sodium ion transport and protein kinase C activity

scientific article

New-generation screening assays for the detection of anti-influenza compounds targeting viral and host functions.

scientific article published on 06 August 2013

Newcastle disease virus (NDV)-based assay demonstrates interferon-antagonist activity for the NDV V protein and the Nipah virus V, W, and C proteins

scientific article

Nipah virus V and W proteins have a common STAT1-binding domain yet inhibit STAT1 activation from the cytoplasmic and nuclear compartments, respectively

scientific article

Nipah virus edits its P gene at high frequency to express the V and W proteins.

scientific article published on 11 February 2009

Nipah virus sequesters inactive STAT1 in the nucleus via a P gene-encoded mechanism

scientific article

Novel Nipah virus immune-antagonism strategy revealed by experimental and computational study

scientific article

Nuclear localization of the Nipah virus W protein allows for inhibition of both virus- and toll-like receptor 3-triggered signaling pathways

scientific article published on May 2005

SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses

scientific article published in February 2018

Serum- and glucocorticoid-regulated kinase 1 is required for nuclear export of the ribonucleoprotein of influenza A virus

scientific article published on 13 March 2013

Successes and challenges in the antiviral field.

scientific article published on 12 September 2013

The Next Wave of Influenza Drugs.

scientific article published on 11 September 2017

The host interactome of influenza virus presents new potential targets for antiviral drugs ⬇️

scientific article published on August 8, 2011

Transcription Elongation Can Affect Genome 3D Structure

scientific article published on 23 August 2018

Transcriptome Profiling of the Virus-Induced Innate Immune Response in Pteropus vampyrus and Its Attenuation by Nipah Virus Interferon Antagonist Functions

scientific article

Uncovering the global host cell requirements for influenza virus replication via RNAi screening.

scientific article published on 27 January 2011

List of works by Megan L. Shaw

A Potent Anti-influenza Compound Blocks Fusion through Stabilization of the Prefusion Conformation of the Hemagglutinin Protein

A Sendai virus-derived RNA agonist of RIG-I as a virus vaccine adjuvant.

A novel small molecule inhibitor of influenza A viruses that targets polymerase function and indirectly induces interferon

An Influenza Virus Entry Inhibitor Targets Class II PI3 Kinase and Synergizes with Oseltamivir

Author Correction: SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses.

Broad Spectrum Inhibitor of Influenza A and B Viruses Targeting the Viral Nucleoprotein.

Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis

Cellular proteins in influenza virus particles

Characterisation of the differences between hepatitis C virus genotype 3 and 1 glycoproteins.

Ebola virus VP24 binds karyopherin alpha1 and blocks STAT1 nuclear accumulation

Frequency, kinetics and determinants of viable SARS-CoV-2 in bioaerosols from ambulatory COVID-19 patients infected with the Beta, Delta or Omicron variants

Henipaviruses Employ a Multifaceted Approach to Evade the Antiviral Interferon Response ⬇️

High-Throughput Minigenome System for Identifying Small-Molecule Inhibitors of Ebola Virus Replication

Human host factors required for influenza virus replication

Identification of small molecules with type I interferon inducing properties by high-throughput screening

Influenza

Inhibition of arenavirus by A3, a pyrimidine biosynthesis inhibitor.

Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding.

Modulation of influenza virus replication by alteration of sodium ion transport and protein kinase C activity

New-generation screening assays for the detection of anti-influenza compounds targeting viral and host functions.

Newcastle disease virus (NDV)-based assay demonstrates interferon-antagonist activity for the NDV V protein and the Nipah virus V, W, and C proteins

Nipah virus V and W proteins have a common STAT1-binding domain yet inhibit STAT1 activation from the cytoplasmic and nuclear compartments, respectively

Nipah virus edits its P gene at high frequency to express the V and W proteins.

Nipah virus sequesters inactive STAT1 in the nucleus via a P gene-encoded mechanism

Novel Nipah virus immune-antagonism strategy revealed by experimental and computational study

Nuclear localization of the Nipah virus W protein allows for inhibition of both virus- and toll-like receptor 3-triggered signaling pathways

SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses

Serum- and glucocorticoid-regulated kinase 1 is required for nuclear export of the ribonucleoprotein of influenza A virus

Successes and challenges in the antiviral field.

The Next Wave of Influenza Drugs.

The host interactome of influenza virus presents new potential targets for antiviral drugs ⬇️

Transcription Elongation Can Affect Genome 3D Structure

Transcriptome Profiling of the Virus-Induced Innate Immune Response in Pteropus vampyrus and Its Attenuation by Nipah Virus Interferon Antagonist Functions

Uncovering the global host cell requirements for influenza virus replication via RNAi screening.