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List of works by Ritva Heljasvaara

A cryptic frizzled module in cell surface collagen 18 inhibits Wnt/beta-catenin signaling

scientific article (publication date: 2008)

A heterologous prime-boost regime using DNA and recombinant vaccinia virus expressing the Leishmania infantum P36/LACK antigen protects BALB/c mice from cutaneous leishmaniasis.

scientific article published in January 2002

ADAMTS-12 metalloprotease is necessary for normal inflammatory response

scientific article

An extracellular matrix signature in leukemia precursor cells and acute myeloid leukemia.

scientific article published on 14 April 2017

Arresten, a collagen-derived angiogenesis inhibitor, suppresses invasion of squamous cell carcinoma.

scientific article

Basement membrane zone collagens XV and XVIII/proteoglycans mediate leukocyte influx in renal ischemia/reperfusion ⬇️

scientific article

Collagen XVIII in tissue homeostasis and dysregulation - Lessons learned from model organisms and human patients

scientific article

Collagen XVIII modulation is altered during progression of oral dysplasia and carcinoma.

scientific article published on January 2007

Collagen XVIII short isoform is critical for retinal vascularization, and overexpression of the Tsp-1 domain affects eye growth and cataract formation.

scientific article

Collagen XVIII, a basement membrane heparan sulfate proteoglycan, interacts with L-selectin and monocyte chemoattractant protein-1.

scientific article published on 28 January 2003

Collagen XVIII/endostatin is associated with the epithelial-mesenchymal transformation in the atrioventricular valves during cardiac development

scientific article published on 01 January 2006

Collagen XVIII/endostatin shows a ubiquitous distribution in human ocular tissues and endostatin-containing fragments accumulate in ocular fluid samples

scientific article published on 13 April 2006

Collagens XV and XVIII show different expression and localisation in cutaneous squamous cell carcinoma: type XV appears in tumor stroma, while XVIII becomes upregulated in tumor cells and lost from microvessels.

scientific article published on 14 December 2015

Complement Component C3 and Complement Factor B Promote Growth of Cutaneous Squamous Cell Carcinoma

scientific article

Deletion of the endothelial Bmx tyrosine kinase decreases tumor angiogenesis and growth

scientific article published on 16 May 2012

Differential expression of collagen types XVIII/endostatin and XV in normal, keratoconus, and scarred human corneas.

scientific article

Elevated VEGF-D Modulates Tumor Inflammation and Reduces the Growth of Carcinogen-Induced Skin Tumors

scientific article

Endostatin Inhibits Human Tongue Carcinoma Cell Invasion and Intravasation and Blocks the Activation of Matrix Metalloprotease-2, -9, and -13 ⬇️

scientific article published on April 10, 2003

Endostatin induces proliferation of oral carcinoma cells but its effect on invasion is modified by the tumor microenvironment

scientific article published on 22 June 2015

Endostatin overexpression inhibits lymphangiogenesis and lymph node metastasis in mice

scientific article

Endostatin, an inhibitor of angiogenesis, decreases after bidirectional superior cavopulmonary anastamosis.

scientific article published on 8 September 2012

EphB2 Promotes Progression of Cutaneous Squamous Cell Carcinoma.

scientific article

Expression of VEGF and collagen XVIII in meningiomas: correlations with histopathological and MRI characteristics.

scientific article published on 20 April 2013

Expression of a specific extracellular matrix signature is a favorable prognostic factor in acute myeloid leukemia.

scientific article published on 13 December 2017

Expression of collagen XVIII and MMP-20 in developing teeth and odontogenic tumors.

scientific article

Generation of biologically active endostatin fragments from human collagen XVIII by distinct matrix metalloproteases.

scientific article published on July 2005

Image-based assessment of microvascular function and structure in collagen XV- and XVIII-deficient mice.

scientific article

Lack of collagen XV is protective after ischemic stroke in mice.

scientific article published on 12 January 2017

Lack of collagen XVIII accelerates cutaneous wound healing, while overexpression of its endostatin domain leads to delayed healing.

scientific article published in April 2008

Matrix metalloproteinases process the laminin-5 gamma 2-chain and regulate epithelial cell migration

scientific article published on 01 April 2003

Redox-fibrosis: Impact of TGFβ1 on ROS generators, mediators and functional consequences

scientific article

Serpin peptidase inhibitor clade A member 1 (SerpinA1) is a novel biomarker for progression of cutaneous squamous cell carcinoma

scientific article

Significant Role of Collagen XVII And Integrin β4 in Migration and Invasion of The Less Aggressive Squamous Cell Carcinoma Cells.

scientific article published on 22 March 2017

Soluble endostatin is a novel inhibitor of epithelial repair in idiopathic pulmonary fibrosis

scientific article published on 13 October 2008

Specific collagen XVIII isoforms promote adipose tissue accrual via mechanisms determining adipocyte number and affect fat deposition

scientific article

The ADAMTS12 metalloproteinase exhibits anti-tumorigenic properties through modulation of the Ras-dependent ERK signalling pathway

scientific article

The major core protein P4a (A10L gene) of vaccinia virus is essential for correct assembly of viral DNA into the nucleoprotein complex to form immature viral particles.

scientific article published on July 2001

Tumor hepatocytes and basement membrane-Producing cells specifically express two different forms of the endostatin precursor, collagen XVIII, in human liver cancers

scientific article published on 01 April 2001

Type XVIII collagen degradation products in acute lung injury

scientific article

Understanding the extracellular matrix in acute myeloid leukemia.

scientific article published in November 2017

Vanin 1 (VNN1) levels predict poor outcome in acute myeloid leukemia

scientific article

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