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List of works by Alex Kentsis

Activity of a selective inhibitor of nuclear export, selinexor (KPT-330), against AML-initiating cells engrafted into immunosuppressed NSG mice.

scientific article published on 23 July 2015

Acute myeloid/T-lymphoblastic leukaemia (AMTL): a distinct category of acute leukaemias with common pathogenesis in need of improved therapy.

scientific article published on 14 February 2018

Author Correction: PGBD5 promotes site-specific oncogenic mutations in human tumors

scientific article published on 11 September 2020

Biological properties of ligand-dependent activation of the MET receptor kinase in acute myeloid leukemia.

scientific article

Challenges and opportunities for discovery of disease biomarkers using urine proteomics.

scientific article published in February 2011

Colorimetric and longitudinal analysis of leukocoria in recreational photographs of children with retinoblastoma

scientific article

Composition and assembly of STAT-targeting ubiquitin ligase complexes: paramyxovirus V protein carboxyl terminus is an oligomerization domain.

scientific article

Construction of macromolecular assemblages in eukaryotic processes and their role in human disease: linking RINGs together

scientific article

Correspondence patterns: mechanisms and models of human dynamics.

scientific article published on May 2006

DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia

scientific article published on 02 July 2018

Detection and diagnostic value of urine leucine-rich α-2-glycoprotein in children with suspected acute appendicitis.

scientific article published on 02 February 2012

Discordant haemophilia A in male siblings due to a de novo mutation on a familial missense mutant allele.

scientific article

Discovery of Protein Modifications Using Differential Tandem Mass Spectrometry Proteomics

scientific article published on 22 March 2021

Distinct and dynamic requirements for mTOR signaling in hematopoiesis and leukemogenesis.

scientific article

Emerging functions of DNA transposases and oncogenic mutators in childhood cancer development

article

Eukaryotic translation initiation factor 4E activity is modulated by HOXA9 at multiple levels.

scientific article

Forward genetic screen of human transposase genomic rearrangements

scientific article

Genetic mechanisms of primary chemotherapy resistance in pediatric acute myeloid leukemia

scientific article published on 13 February 2019

Genomic DNA transposition induced by human PGBD5

scientific article

Inactivation of VHL by tumorigenic mutations that disrupt dynamic coupling of the pVHL.hypoxia-inducible transcription factor-1alpha complex.

scientific article

KPT-330 inhibitor of CRM1 (XPO1)-mediated nuclear export has selective anti-leukaemic activity in preclinical models of T-cell acute lymphoblastic leukaemia and acute myeloid leukaemia.

scientific article published on 04 February 2013

MC-PHS: a Monte Carlo implementation of the primary hydration shell for protein folding and design.

scientific article

Mechanisms of androgen induction of sebocyte differentiation

scientific article published on 01 January 1998

Nedd8 on cullin: building an expressway to protein destruction.

scientific article

Optimized Cross-Linking Mass Spectrometry for in Situ Interaction Proteomics

scientific article published on 24 May 2019

Origin of the sequence-dependent polyproline II structure in unfolded peptides

scientific article published on 01 December 2005

PGBD5 promotes site-specific oncogenic mutations in human tumors

scientific article published on 15 May 2017

Peptidomimetic blockade of MYB in acute myeloid leukemia

scientific article published on 9 January 2018

Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia.

scientific article published on 09 January 2014

Physical mechanisms and biological significance of supramolecular protein self-assembly.

scientific article published on April 2004

Prohibitin promotes de-differentiation and is a potential therapeutic target in neuroblastoma.

scientific article published on 18 April 2019

ProteoModlR for functional proteomic analysis.

scientific article

ProteomeGenerator: A framework for comprehensive proteomics based on de novo transcriptome assembly and high-accuracy peptide mass spectral matching

scientific article published on 19 October 2018

Rat preputial sebocyte differentiation involves peroxisome proliferator-activated receptors

scientific article published on 01 February 1999

Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap

scientific article

Selective Requirement of MYB for Oncogenic Hyperactivation of a Translocated Enhancer in Leukemia

publication published on 12 May 2021

The RING domains of the promyelocytic leukemia protein PML and the arenaviral protein Z repress translation by directly inhibiting translation initiation factor eIF4E.

scientific article published in September 2001

Therapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid tumors

scientific article

Trifluoroethanol promotes helix formation by destabilizing backbone exposure: desolvation rather than native hydrogen bonding defines the kinetic pathway of dimeric coiled coil folding

scientific article published on 01 October 1998

Urine proteomics for discovery of improved diagnostic markers of Kawasaki disease

scientific article published on December 20, 2012

Why do young people get cancer?

scientific article published on 11 May 2020