List of works - Leigh M Marsh

Activation of EP4 receptors prevents endotoxin-induced neutrophil infiltration into the airways and enhances microvascular barrier function

scientific article

Antihistone Properties of C1 Esterase Inhibitor Protect against Lung Injury

scientific article published on 22 December 2016

Autofluorescence multiphoton microscopy for visualization of tissue morphology and cellular dynamics in murine and human airways

scientific article

BDNF/TrkB signaling augments smooth muscle cell proliferation in pulmonary hypertension

scientific article published on 8 October 2012

Butyrate ameliorates allergic airway inflammation by limiting eosinophil trafficking and survival

scientific article published on 11 May 2019

CD133+ cells in pulmonary arterial hypertension

scientific article

Clara cells drive eosinophil accumulation in allergic asthma

scientific article published on 04 August 2011

Compartment-specific expression of collagens and their processing enzymes in intrapulmonary arteries of IPAH patients

scientific article published on 3 April 2015

Compartmental and temporal dynamics of chronic inflammation and airway remodelling in a chronic asthma mouse model

scientific article (publication date: 2014)

Disconnect between Fibrotic Response and Right Ventricular Dysfunction

scientific article published on 01 June 2019

Distinct differences in gene expression patterns in pulmonary arteries of patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis with pulmonary hypertension.

scientific article

Docosahexaenoic acid causes rapid pulmonary arterial relaxation via KCa channel-mediated hyperpolarisation in pulmonary hypertension

scientific article

Dysregulation of the IL-13 receptor system: a novel pathomechanism in pulmonary arterial hypertension.

scientific article

Echocardiographic Measurement of Right Ventricular Diastolic Parameters in Mouse

scientific article published on 27 April 2019

Endothelin-1 driven proliferation of pulmonary arterial smooth muscle cells is c-fos dependent.

scientific article published on 10 July 2014

Enolase-1 promotes plasminogen-mediated recruitment of monocytes to the acutely inflamed lung

scientific article published on 30 January 2009

Fhl-1, a new key protein in pulmonary hypertension.

scientific article

Flow Cytometry-Based Cell Type-Specific Assessment of Target Regulation by Pulmonary siRNA Delivery

scientific article published on 01 January 2019

Flow cytometry-based cell type-specific assessment of target regulation by pulmonary siRNA delivery.

scientific article published on January 2013

Fra2 Overexpression in Mice Leads to Non-allergic Asthma Development in an IL-13 Dependent Manner

Functional and molecular factors associated with TAPSE in hypoxic pulmonary hypertension

scientific article published on 22 April 2016

High-mobility group box-1 induces vascular remodelling processes via c-Jun activation

scientific article published on 28 February 2015

Hyperoxia modulates TGF-beta/BMP signaling in a mouse model of bronchopulmonary dysplasia

scientific article published on 27 October 2006

Hypoxic vascular response and ventilation/perfusion matching in end-stage COPD may depend on p22phox.

scientific article published on 20 July 2017

IL-1 receptor blockade skews inflammation towards Th2 in a mouse model of systemic sclerosis

scientific article published on 29 September 2019

Immunomodulation by lipid emulsions in pulmonary inflammation: a randomized controlled trial

scientific article

Impact of atomization technique on the stability and transport efficiency of nebulized liposomes harboring different surface characteristics

scientific article published on November 2014

Increased Expression of p22phox Mediates Airway Hyperresponsiveness in an Experimental Model of Asthma.

scientific article

Interleukin 13- and interleukin 17A-induced pulmonary hypertension phenotype due to inhalation of antigen and fine particles from air pollution

scientific article

Lessons from Transcriptomics in Hypoxia Induced Pulmonary Hypertension: Does the Mouse Strain Matter?

scientific article published on 01 January 2019

Liposomal nanoparticles encapsulating iloprost exhibit enhanced vasodilation in pulmonary arteries

scientific article

Long non-coding RNAs influence the transcriptome in pulmonary arterial hypertension: the role of PAXIP1-AS1

scientific article published on 16 January 2019

Lung dendritic cells elicited by Fms-like tyrosine 3-kinase ligand amplify the lung inflammatory response to lipopolysaccharide

scientific article published on 9 August 2007

Macrophage tumor necrosis factor-alpha induces epithelial expression of granulocyte-macrophage colony-stimulating factor: impact on alveolar epithelial repair.

scientific article

Maternal signals for progeny prevention against allergy and asthma

scientific article published on 03 March 2011

Meprin β contributes to collagen deposition in lung fibrosis

scientific article published on 6 January 2017

Meprinβ, a novel mediator of vascular remodelling underlying pulmonary hypertension

scientific article published on 31 January 2014

Modification of hemodynamic and immune responses to exposure with a weak antigen by the expression of a hypomorphic BMPR2 gene

scientific article

NPY/Y₁ receptor-mediated vasoconstrictory and proliferative effects in pulmonary hypertension

scientific article

Neurotrophic tyrosine kinase receptor B/neurotrophin 4 signaling axis is perturbed in clinical and experimental pulmonary fibrosis.

scientific article

Origin of neomuscularized vessels in mice exposed to chronic hypoxia.

scientific article

PAR-2 inhibition reverses experimental pulmonary hypertension.

scientific article

PDGFRα and αSMA mark two distinct mesenchymal cell populations involved in parenchymal and vascular remodeling in pulmonary fibrosis

scientific article published on 05 February 2020

PKR regulates TLR2/TLR4-dependent signaling in murine alveolar macrophages

scientific article published on 9 August 2007

Paxillin regulates pulmonary arterial smooth muscle cell function in pulmonary hypertension

scientific article

Perspective: ambient air pollution: inflammatory response and effects on the lung's vasculature

scientific article

Pressure Overload Creates Right Ventricular Diastolic Dysfunction in a Mouse Model: Assessment by Echocardiography

scientific article published in April 2015

Receptor for Activated C-Kinase 1, a Novel Interaction Partner of Type II Bone Morphogenetic Protein Receptor, Regulates Smooth Muscle Cell Proliferation in Pulmonary Arterial Hypertension

scientific article published on 21 May 2007

Resident cell lineages are preserved in pulmonary vascular remodeling

scientific article

Rho-Kinase Inhibition Ameliorates Dasatinib-Induced Endothelial Dysfunction and Pulmonary Hypertension.

scientific article

Single-cell transcriptomics reveals skewed cellular communication and phenotypic shift in pulmonary artery remodeling

scientific article published in 2022

Suppression of adrenomedullin contributes to vascular leakage and altered epithelial repair during asthma

scientific article published on 12 June 2012

Surface expression of CD74 by type II alveolar epithelial cells: a potential mechanism for macrophage migration inhibitory factor-induced epithelial repair

scientific article

Targeting TMEM16A to reverse vasoconstriction and remodelling in idiopathic PAH

scientific article published on 25 April 2019

The inflammatory cell landscape in the lungs of patients with idiopathic pulmonary arterial hypertension.

scientific article published on 25 January 2018

Transcription factor Fra-2 and its emerging role in matrix deposition, proliferation and inflammation in chronic lung diseases

scientific article published on 29 August 2019

Transcriptome profiling of primary murine monocytes, lung macrophages and lung dendritic cells reveals a distinct expression of genes involved in cell trafficking

scientific article published on 16 January 2009

Transcriptome profiling reveals the complexity of pirfenidone effects in idiopathic pulmonary fibrosis

scientific article published on 22 November 2018

Visualization of intrapulmonary lymph vessels in healthy and inflamed murine lung using CD90/Thy-1 as a marker

scientific article

List of works by Leigh M Marsh

Activation of EP4 receptors prevents endotoxin-induced neutrophil infiltration into the airways and enhances microvascular barrier function

Antihistone Properties of C1 Esterase Inhibitor Protect against Lung Injury

Autofluorescence multiphoton microscopy for visualization of tissue morphology and cellular dynamics in murine and human airways

BDNF/TrkB signaling augments smooth muscle cell proliferation in pulmonary hypertension

Butyrate ameliorates allergic airway inflammation by limiting eosinophil trafficking and survival

CD133+ cells in pulmonary arterial hypertension

Clara cells drive eosinophil accumulation in allergic asthma

Compartment-specific expression of collagens and their processing enzymes in intrapulmonary arteries of IPAH patients

Compartmental and temporal dynamics of chronic inflammation and airway remodelling in a chronic asthma mouse model

Disconnect between Fibrotic Response and Right Ventricular Dysfunction

Distinct differences in gene expression patterns in pulmonary arteries of patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis with pulmonary hypertension.

Docosahexaenoic acid causes rapid pulmonary arterial relaxation via KCa channel-mediated hyperpolarisation in pulmonary hypertension

Dysregulation of the IL-13 receptor system: a novel pathomechanism in pulmonary arterial hypertension.

Echocardiographic Measurement of Right Ventricular Diastolic Parameters in Mouse

Endothelin-1 driven proliferation of pulmonary arterial smooth muscle cells is c-fos dependent.

Enolase-1 promotes plasminogen-mediated recruitment of monocytes to the acutely inflamed lung

Fhl-1, a new key protein in pulmonary hypertension.

Flow Cytometry-Based Cell Type-Specific Assessment of Target Regulation by Pulmonary siRNA Delivery

Flow cytometry-based cell type-specific assessment of target regulation by pulmonary siRNA delivery.

Fra2 Overexpression in Mice Leads to Non-allergic Asthma Development in an IL-13 Dependent Manner

Functional and molecular factors associated with TAPSE in hypoxic pulmonary hypertension

High-mobility group box-1 induces vascular remodelling processes via c-Jun activation

Hyperoxia modulates TGF-beta/BMP signaling in a mouse model of bronchopulmonary dysplasia

Hypoxic vascular response and ventilation/perfusion matching in end-stage COPD may depend on p22phox.

IL-1 receptor blockade skews inflammation towards Th2 in a mouse model of systemic sclerosis

Immunomodulation by lipid emulsions in pulmonary inflammation: a randomized controlled trial

Impact of atomization technique on the stability and transport efficiency of nebulized liposomes harboring different surface characteristics

Increased Expression of p22phox Mediates Airway Hyperresponsiveness in an Experimental Model of Asthma.

Interleukin 13- and interleukin 17A-induced pulmonary hypertension phenotype due to inhalation of antigen and fine particles from air pollution

Lessons from Transcriptomics in Hypoxia Induced Pulmonary Hypertension: Does the Mouse Strain Matter?

Liposomal nanoparticles encapsulating iloprost exhibit enhanced vasodilation in pulmonary arteries

Long non-coding RNAs influence the transcriptome in pulmonary arterial hypertension: the role of PAXIP1-AS1

Lung dendritic cells elicited by Fms-like tyrosine 3-kinase ligand amplify the lung inflammatory response to lipopolysaccharide

Macrophage tumor necrosis factor-alpha induces epithelial expression of granulocyte-macrophage colony-stimulating factor: impact on alveolar epithelial repair.

Maternal signals for progeny prevention against allergy and asthma

Meprin β contributes to collagen deposition in lung fibrosis

Meprinβ, a novel mediator of vascular remodelling underlying pulmonary hypertension

Modification of hemodynamic and immune responses to exposure with a weak antigen by the expression of a hypomorphic BMPR2 gene

NPY/Y₁ receptor-mediated vasoconstrictory and proliferative effects in pulmonary hypertension

Neurotrophic tyrosine kinase receptor B/neurotrophin 4 signaling axis is perturbed in clinical and experimental pulmonary fibrosis.

Origin of neomuscularized vessels in mice exposed to chronic hypoxia.

PAR-2 inhibition reverses experimental pulmonary hypertension.

PDGFRα and αSMA mark two distinct mesenchymal cell populations involved in parenchymal and vascular remodeling in pulmonary fibrosis

PKR regulates TLR2/TLR4-dependent signaling in murine alveolar macrophages

Paxillin regulates pulmonary arterial smooth muscle cell function in pulmonary hypertension

Perspective: ambient air pollution: inflammatory response and effects on the lung's vasculature

Pressure Overload Creates Right Ventricular Diastolic Dysfunction in a Mouse Model: Assessment by Echocardiography

Receptor for Activated C-Kinase 1, a Novel Interaction Partner of Type II Bone Morphogenetic Protein Receptor, Regulates Smooth Muscle Cell Proliferation in Pulmonary Arterial Hypertension

Resident cell lineages are preserved in pulmonary vascular remodeling

Rho-Kinase Inhibition Ameliorates Dasatinib-Induced Endothelial Dysfunction and Pulmonary Hypertension.

Single-cell transcriptomics reveals skewed cellular communication and phenotypic shift in pulmonary artery remodeling

Suppression of adrenomedullin contributes to vascular leakage and altered epithelial repair during asthma

Surface expression of CD74 by type II alveolar epithelial cells: a potential mechanism for macrophage migration inhibitory factor-induced epithelial repair

Targeting TMEM16A to reverse vasoconstriction and remodelling in idiopathic PAH

The inflammatory cell landscape in the lungs of patients with idiopathic pulmonary arterial hypertension.

Transcription factor Fra-2 and its emerging role in matrix deposition, proliferation and inflammation in chronic lung diseases

Transcriptome profiling of primary murine monocytes, lung macrophages and lung dendritic cells reveals a distinct expression of genes involved in cell trafficking

Transcriptome profiling reveals the complexity of pirfenidone effects in idiopathic pulmonary fibrosis

Visualization of intrapulmonary lymph vessels in healthy and inflamed murine lung using CD90/Thy-1 as a marker