List of works - Tracy G. Anthony

ATF4-dependent regulation of the JMJD3 gene during amino acid deprivation can be rescued in Atf4-deficient cells by inhibition of deacetylation.

scientific article

Age modulates liver responses to asparaginase-induced amino acid stress in mice

scientific article published on 14 August 2019

Ascorbic acid supplementation does not alter oxidative stress markers in healthy volunteers engaged in a supervised exercise program

scientific article published on 26 October 2015

Coping with stress: eIF2 kinases and translational control

scientific article (publication date: February 2006)

Defining meal requirements for protein to optimize metabolic roles of amino acids

scientific article published on 29 April 2015

Detection of amino acid deprivation in the central nervous system ⬇️

scientific article published on January 1, 2013

Dietary Methionine Restriction Regulates Liver Protein Synthesis and Gene Expression Independently of Eukaryotic Initiation Factor 2 Phosphorylation in Mice

scientific article published on 26 April 2017

Dietary Sulfur Amino Acid Restriction and the Integrated Stress Response: Mechanistic Insights

scientific article published on 15 June 2019

EXtENDINg beta cell survival by UPRegulating ATF4 translation

scientific article

Evaluating the effect of 20-hydroxyecdysone (20HE) on mechanistic target of rapamycin complex 1 (mTORC1) signaling in the skeletal muscle and liver of rats.

scientific article

Feeding meals containing soy or whey protein after exercise stimulates protein synthesis and translation initiation in the skeletal muscle of male rats

scientific article published on 01 February 2007

Fragmented population structure of plasmodium falciparum in a region of declining endemicity.

scientific article published on 25 March 2005

GCN2 is required to increase fibroblast growth factor 21 and maintain hepatic triglyceride homeostasis during asparaginase treatment.

scientific article

GCN2 protein kinase is required to activate amino acid deprivation responses in mice treated with the anti-cancer agent L-asparaginase.

scientific article published on 25 September 2009

General control nonderepressible 2 (GCN2) kinase protects oligodendrocytes and white matter during branched-chain amino acid deficiency in mice

scientific article published on 09 September 2013

General control nonderepressible 2 deletion predisposes to asparaginase-associated pancreatitis in mice

scientific article published on 11 March 2016

Homeostatic responses to amino acid insufficiency.

scientific article

Identification of domains within the epsilon-subunit of the translation initiation factor eIF2B that are necessary for guanine nucleotide exchange activity and eIF2B holoprotein formation

scientific article (publication date: 21 June 2000)

Intensity-dependent and sex-specific alterations in hepatic triglyceride metabolism in mice following acute exercise.

scientific article published on 25 September 2014

Leucine or carbohydrate supplementation reduces AMPK and eEF2 phosphorylation and extends postprandial muscle protein synthesis in rats

scientific article published on 13 September 2011

Leucine reduces the duration of insulin-induced PI 3-kinase activity in rat skeletal muscle.

scientific article published on 31 August 2004

Measuring the Ability of Mice to Sense Dietary Essential Amino Acid Deficiency: The Importance of Amino Acid Status and Timing.

scientific article published in August 2016

Mechanisms of protein balance in skeletal muscle.

scientific article

Obesity challenges the hepatoprotective function of the integrated stress response to asparaginase exposure in mice.

scientific article

Post-meal responses of elongation factor 2 (eEF2) and adenosine monophosphate-activated protein kinase (AMPK) to leucine and carbohydrate supplements for regulating protein synthesis duration and energy homeostasis in rat skeletal muscle.

scientific article published on 13 November 2012

Preservation of liver protein synthesis during dietary leucine deprivation occurs at the expense of skeletal muscle mass in mice deleted for eIF2 kinase GCN2.

scientific article

Reduced amino acid availability inhibits muscle protein synthesis and decreases activity of initiation factor eIF2B

scientific article

Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity

scientific article published on 19 March 2013

Remodeling of lipid metabolism by dietary restriction of essential amino acids

scientific article published on August 2013

Role of GCN2-Independent Signaling Through a Noncanonical PERK/NRF2 Pathway in the Physiological Responses to Dietary Methionine Restriction.

scientific article published on 02 March 2016

Role of activating transcription factor 4 in the hepatic response to amino acid depletion by asparaginase

scientific article

Role of glutamine depletion in directing tissue-specific nutrient stress responses to L-asparaginase.

scientific article

Selective mRNA translation during eIF2 phosphorylation induces expression of IBTKα.

scientific article

TXNIP switches tracks toward a terminal UPR

scientific article published on 01 August 2012

The eIF2 Kinase GCN2 Is Essential for the Murine Immune System to Adapt to Amino Acid Deprivation by Asparaginase ⬇️

scientific article published on September 22, 2010

The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress.

scientific article published on 14 September 2011

The eukaryotic initiation factor 2 kinase GCN2 protects against hepatotoxicity during asparaginase treatment.

scientific article published on 03 September 2013

The leucine content of a complete meal directs peak activation but not duration of skeletal muscle protein synthesis and mammalian target of rapamycin signaling in rats

scientific article published on 29 April 2009

The role of leucine and its metabolites in protein and energy metabolism

scientific article

Transcription factor ATF4 directs basal and stress-induced gene expression in the unfolded protein response and cholesterol metabolism in the liver.

scientific article published on 9 March 2016

Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex.

scientific article

List of works by Tracy G. Anthony

ATF4-dependent regulation of the JMJD3 gene during amino acid deprivation can be rescued in Atf4-deficient cells by inhibition of deacetylation.

Age modulates liver responses to asparaginase-induced amino acid stress in mice

Ascorbic acid supplementation does not alter oxidative stress markers in healthy volunteers engaged in a supervised exercise program

Coping with stress: eIF2 kinases and translational control

Defining meal requirements for protein to optimize metabolic roles of amino acids

Detection of amino acid deprivation in the central nervous system ⬇️

Dietary Methionine Restriction Regulates Liver Protein Synthesis and Gene Expression Independently of Eukaryotic Initiation Factor 2 Phosphorylation in Mice

Dietary Sulfur Amino Acid Restriction and the Integrated Stress Response: Mechanistic Insights

EXtENDINg beta cell survival by UPRegulating ATF4 translation

Evaluating the effect of 20-hydroxyecdysone (20HE) on mechanistic target of rapamycin complex 1 (mTORC1) signaling in the skeletal muscle and liver of rats.

Feeding meals containing soy or whey protein after exercise stimulates protein synthesis and translation initiation in the skeletal muscle of male rats

Fragmented population structure of plasmodium falciparum in a region of declining endemicity.

GCN2 is required to increase fibroblast growth factor 21 and maintain hepatic triglyceride homeostasis during asparaginase treatment.

GCN2 protein kinase is required to activate amino acid deprivation responses in mice treated with the anti-cancer agent L-asparaginase.

General control nonderepressible 2 (GCN2) kinase protects oligodendrocytes and white matter during branched-chain amino acid deficiency in mice

General control nonderepressible 2 deletion predisposes to asparaginase-associated pancreatitis in mice

Homeostatic responses to amino acid insufficiency.

Identification of domains within the epsilon-subunit of the translation initiation factor eIF2B that are necessary for guanine nucleotide exchange activity and eIF2B holoprotein formation

Intensity-dependent and sex-specific alterations in hepatic triglyceride metabolism in mice following acute exercise.

Leucine or carbohydrate supplementation reduces AMPK and eEF2 phosphorylation and extends postprandial muscle protein synthesis in rats

Leucine reduces the duration of insulin-induced PI 3-kinase activity in rat skeletal muscle.

Measuring the Ability of Mice to Sense Dietary Essential Amino Acid Deficiency: The Importance of Amino Acid Status and Timing.

Mechanisms of protein balance in skeletal muscle.

Obesity challenges the hepatoprotective function of the integrated stress response to asparaginase exposure in mice.

Post-meal responses of elongation factor 2 (eEF2) and adenosine monophosphate-activated protein kinase (AMPK) to leucine and carbohydrate supplements for regulating protein synthesis duration and energy homeostasis in rat skeletal muscle.

Preservation of liver protein synthesis during dietary leucine deprivation occurs at the expense of skeletal muscle mass in mice deleted for eIF2 kinase GCN2.

Reduced amino acid availability inhibits muscle protein synthesis and decreases activity of initiation factor eIF2B

Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity

Remodeling of lipid metabolism by dietary restriction of essential amino acids

Role of GCN2-Independent Signaling Through a Noncanonical PERK/NRF2 Pathway in the Physiological Responses to Dietary Methionine Restriction.

Role of activating transcription factor 4 in the hepatic response to amino acid depletion by asparaginase

Role of glutamine depletion in directing tissue-specific nutrient stress responses to L-asparaginase.

Selective mRNA translation during eIF2 phosphorylation induces expression of IBTKα.

TXNIP switches tracks toward a terminal UPR

The eIF2 Kinase GCN2 Is Essential for the Murine Immune System to Adapt to Amino Acid Deprivation by Asparaginase ⬇️

The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress.

The eukaryotic initiation factor 2 kinase GCN2 protects against hepatotoxicity during asparaginase treatment.

The leucine content of a complete meal directs peak activation but not duration of skeletal muscle protein synthesis and mammalian target of rapamycin signaling in rats

The role of leucine and its metabolites in protein and energy metabolism

Transcription factor ATF4 directs basal and stress-induced gene expression in the unfolded protein response and cholesterol metabolism in the liver.

Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex.