List of works - Ana Lucia Nascimento

A newly identified leptospiral adhesin mediates attachment to laminin

scientific article

A newly identified protein of Leptospira interrogans mediates binding to laminin.

scientific article

A novel leptospiral protein increases ICAM-1 and E-selectin expression in human umbilical vein endothelial cells.

scientific article published on November 2007

Adhesins of Leptospira interrogans mediate the interaction to fibrinogen and inhibit fibrin clot formation in vitro

scientific article

Adjuvant activity of Mycobacterium bovis BCG expressing CRM197 on the immune response induced by BCG expressing tetanus toxin fragment C.

scientific article published in January 2004

Binding of human plasminogen by the lipoprotein LipL46 of Leptospira interrogans

scientific article published on 3 November 2017

CHEMIEXCITATION IN THE ARACHIDONIC ACID CASCADE

scientific article published on 01 March 1991

Cells transfected with transferrin receptor cDNA lacking the iron regulatory domain become more sensitive to the DNA-damaging action of oxidative stress.

scientific article

Characterization of LIC11207, a novel leptospiral protein that is recognized by human convalescent sera and prevents apoptosis of polymorphonuclear leukocytes.

scientific article published on 22 October 2012

Characterization of a novel protein of Leptospira interrogans exhibiting plasminogen, vitronectin and complement binding properties

scientific article published on 06 January 2019

Characterization of novel OmpA-like protein of Leptospira interrogans that binds extracellular matrix molecules and plasminogen

scientific article

Characterization of three novel adhesins of Leptospira interrogans.

scientific article published on 19 August 2013

Chimeras could help in the fight against leptospirosis.

scientific article

Decrease in antithrombin III and prothrombin serum levels contribute to coagulation disorders during leptospirosis

scientific article published on 2 June 2016

Development of transcriptional fusions to assess Leptospira interrogans promoter activity.

scientific article published on 18 March 2011

Evaluation of Lsa46 and Lsa77 Leptospiral Proteins for Their Immunoprotective Activities in Hamster Model of Leptospirosis.

scientific article published on 10 June 2018

Evaluation of leptospiral recombinant antigens MPL17 and MPL21 for serological diagnosis of leptospirosis by enzyme-linked immunosorbent assays.

scientific article published on 17 September 2008

Evaluation of two novel leptospiral proteins for their interaction with human host components.

scientific article

Features of two new proteins with OmpA-like domains identified in the genome sequences of Leptospira interrogans

scientific article published on 7 April 2015

Features of two proteins of Leptospira interrogans with potential role in host-pathogen interactions

scientific article

Functional and immunological evaluation of two novel proteins of Leptospira spp.

scientific article

GENERATION OF ELECTRONICALLY EXCITED STATES IN SITU. POLYMORPHONUCLEAR LEUKOCYTES TREATED WITH PHENYLACETALDEHYDE

scientific article published on 01 July 1987

Gene silencing based on RNA-guided catalytically inactive Cas9 (dCas9): a new tool for genetic engineering in Leptospira

scientific article published in Scientific Reports

Generation of electronically excited triplet species at the cellular level: a potential source of genotoxicity.

scientific article

Genome sequence of Aedes aegypti, a major arbovirus vector

scientific article

Heparin-binding protein release is strongly induced by Leptospira spp. and is a candidate for an early diagnostic marker of human leptospirosis

scientific article published on 01 February 2019

Heterologous Expression of the Pathogen-Specific LIC11711 Gene in the Saprophyte L. biflexa Increases Bacterial Binding to Laminin and Plasminogen

scientific article published on 22 July 2020

High-level expression of tetanus toxin fragment C‒thioredoxin fusion protein in Escherichia coli

scientific article published on 01 April 2000

Identification of a novel protein in the genome sequences of Leptospira interrogans with the ability to interact with host's components

scientific article published on 22 January 2019

Immune response and protective profile elicited by a multi-epitope chimeric protein derived from Leptospira interrogans.

scientific article published on February 2017

In Silico Structural and Functional Characterization of HtrA Proteins of <i>Leptospira</i> spp.: Possible Implications in Pathogenesis

scientific article published on 28 November 2020

In vitro evidence for immune evasion activity by human plasmin associated to pathogenic Leptospira interrogans

article

Induction of boosted immune response in mice by leptospiral surface proteins expressed in fusion with DnaK.

scientific article

Induction of neutralizing antibodies against diphtheria toxin by priming with recombinant Mycobacterium bovis BCG expressing CRM(197), a mutant diphtheria toxin.

scientific article published on February 2001

Interaction of Leptospira interrogans with human proteolytic systems enhances dissemination through endothelial cells and protease levels.

scientific article published on 11 March 2013

Interaction of spirochetes with the host fibrinolytic system and potential roles in pathogenesis

scientific article published on 27 April 2015

Intermediate and C-terminal regions of leptospiral adhesin Lsa66 are responsible for binding with plasminogen and extracellular matrix components.

scientific article

Intracellular generation of electronically excited states. Polymorphonuclear leukocytes challenged with a precursor of triplet acetone

scientific article published on 01 May 1986

Leptospira Infection Interferes with the Prothrombinase Complex Assembly during Experimental Leptospirosis.

scientific article published on 28 March 2017

Leptospira interrogans Lsa23 protein recruits plasminogen, factor H and C4BP from normal human serum and mediates C3b and C4b degradation.

scientific article published on 27 November 2015

Leptospira interrogans outer membrane protein LipL21 is a potent inhibitor of neutrophil myeloperoxidase.

scientific article published on 13 December 2017

Leptospira interrogans reduces fibrin clot formation by modulating human thrombin activity via exosite I.

scientific article

Leptospira spp.: Novel insights into host-pathogen interactions

scientific article published on 14 December 2015

Leptospiral extracellular matrix adhesins as mediators of pathogen-host interactions

scientific article published on 11 December 2013

Lp95, a novel leptospiral protein that binds extracellular matrix components and activates e-selectin on endothelial cells.

scientific article

Lsa21, a novel leptospiral protein binding adhesive matrix molecules and present during human infection.

scientific article published on 29 April 2008

Lsa63, a newly identified surface protein of Leptospira interrogans binds laminin and collagen IV.

scientific article published on 30 October 2009

Mammalian cell entry (Mce) protein of Leptospira interrogans binds extracellular matrix components, plasminogen and β2 integrin.

scientific article published on 28 July 2016

Modulation of Hemostatic and Inflammatory Responses by Leptospira Spp

scientific article

Multifunctional and Redundant Roles of Leptospira interrogans Proteins in Bacterial-Adhesion and fibrin clotting inhibition.

scientific article published on 31 May 2017

Novel Leptospira interrogans protein Lsa32 is expressed during infection and binds laminin and plasminogen.

scientific article published on 27 January 2015

OmpL1 is an extracellular matrix- and plasminogen-interacting protein of Leptospira spp

scientific article

Overexpression of a synthetic gene encoding human alpha interferon in Escherichia coli.

scientific article

Plasminogen binding proteins and plasmin generation on the surface of Leptospira spp.: the contribution to the bacteria-host interactions

scientific article

Proteomics as a tool to understand Leptospira physiology and virulence: Recent advances, challenges and clinical implications.

scientific article published in March 2018

Putative outer membrane proteins of Leptospira interrogans stimulate human umbilical vein endothelial cells (HUVECS) and express during infection.

scientific article published on 20 August 2008

Research on bacterial virulence in the developing countries

scientific article published on 2 February 2015

Schiff base formation with amino acids enhances light emission and damage induced in neutrophils by phenylacetaldehyde

scientific article published on 01 April 1989

Schistosoma mansoni venom allergen-like protein 18 (SmVAL18) is a plasminogen-binding protein secreted during the early stages of mammalian-host infection.

scientific article published on 22 February 2018

Sm14 of Schistosoma mansoni in fusion with tetanus toxin fragment C induces immunoprotection against tetanus and schistosomiasis in mice.

scientific article published on October 2004

THE PEROXIDATIVE METABOLISM OF TENOXICAM PRODUCES EXCITED SPECIES

scientific article published on 01 February 1993

The contribution of 700,000 ORF sequence tags to the definition of the human transcriptome.

scientific article

The crystal structure of the leptospiral hypothetical protein LIC12922 reveals homology with the periplasmic chaperone SurA

scientific article

The generation and utilization of a cancer-oriented representation of the human transcriptome by using expressed sequence tags

scientific article published on 30 October 2003

The genome sequence of the plant pathogen Xylella fastidiosa. The Xylella fastidiosa Consortium of the Organization for Nucleotide Sequencing and Analysis

scientific article published in July 2000

The recombinant LIC10508 is a plasma fibronectin, plasminogen, fibrinogen and C4BP-binding protein of Leptospira interrogans.

scientific article

The role of Lsa23 to mediate the interaction of Leptospira interrogans with the terminal complement components pathway.

scientific article published on 28 September 2017

Transcriptome analysis of the acoelomate human parasite Schistosoma mansoni

scientific article published on 14 September 2003

Whole-genome analysis of Leptospira interrogans to identify potential vaccine candidates against leptospirosis.

scientific article published in March 2005

List of works by Ana Lucia Nascimento

A newly identified leptospiral adhesin mediates attachment to laminin

A newly identified protein of Leptospira interrogans mediates binding to laminin.

A novel leptospiral protein increases ICAM-1 and E-selectin expression in human umbilical vein endothelial cells.

Adhesins of Leptospira interrogans mediate the interaction to fibrinogen and inhibit fibrin clot formation in vitro

Adjuvant activity of Mycobacterium bovis BCG expressing CRM197 on the immune response induced by BCG expressing tetanus toxin fragment C.

Binding of human plasminogen by the lipoprotein LipL46 of Leptospira interrogans

CHEMIEXCITATION IN THE ARACHIDONIC ACID CASCADE

Cells transfected with transferrin receptor cDNA lacking the iron regulatory domain become more sensitive to the DNA-damaging action of oxidative stress.

Characterization of LIC11207, a novel leptospiral protein that is recognized by human convalescent sera and prevents apoptosis of polymorphonuclear leukocytes.

Characterization of a novel protein of Leptospira interrogans exhibiting plasminogen, vitronectin and complement binding properties

Characterization of novel OmpA-like protein of Leptospira interrogans that binds extracellular matrix molecules and plasminogen

Characterization of three novel adhesins of Leptospira interrogans.

Chimeras could help in the fight against leptospirosis.

Decrease in antithrombin III and prothrombin serum levels contribute to coagulation disorders during leptospirosis

Development of transcriptional fusions to assess Leptospira interrogans promoter activity.

Evaluation of Lsa46 and Lsa77 Leptospiral Proteins for Their Immunoprotective Activities in Hamster Model of Leptospirosis.

Evaluation of leptospiral recombinant antigens MPL17 and MPL21 for serological diagnosis of leptospirosis by enzyme-linked immunosorbent assays.

Evaluation of two novel leptospiral proteins for their interaction with human host components.

Features of two new proteins with OmpA-like domains identified in the genome sequences of Leptospira interrogans

Features of two proteins of Leptospira interrogans with potential role in host-pathogen interactions

Functional and immunological evaluation of two novel proteins of Leptospira spp.

GENERATION OF ELECTRONICALLY EXCITED STATES IN SITU. POLYMORPHONUCLEAR LEUKOCYTES TREATED WITH PHENYLACETALDEHYDE

Gene silencing based on RNA-guided catalytically inactive Cas9 (dCas9): a new tool for genetic engineering in Leptospira

Generation of electronically excited triplet species at the cellular level: a potential source of genotoxicity.

Genome sequence of Aedes aegypti, a major arbovirus vector

Heparin-binding protein release is strongly induced by Leptospira spp. and is a candidate for an early diagnostic marker of human leptospirosis

Heterologous Expression of the Pathogen-Specific LIC11711 Gene in the Saprophyte L. biflexa Increases Bacterial Binding to Laminin and Plasminogen

High-level expression of tetanus toxin fragment C‒thioredoxin fusion protein in Escherichia coli

Identification of a novel protein in the genome sequences of Leptospira interrogans with the ability to interact with host's components

Immune response and protective profile elicited by a multi-epitope chimeric protein derived from Leptospira interrogans.

In Silico Structural and Functional Characterization of HtrA Proteins of <i>Leptospira</i> spp.: Possible Implications in Pathogenesis

In vitro evidence for immune evasion activity by human plasmin associated to pathogenic Leptospira interrogans

Induction of boosted immune response in mice by leptospiral surface proteins expressed in fusion with DnaK.

Induction of neutralizing antibodies against diphtheria toxin by priming with recombinant Mycobacterium bovis BCG expressing CRM(197), a mutant diphtheria toxin.

Interaction of Leptospira interrogans with human proteolytic systems enhances dissemination through endothelial cells and protease levels.

Interaction of spirochetes with the host fibrinolytic system and potential roles in pathogenesis

Intermediate and C-terminal regions of leptospiral adhesin Lsa66 are responsible for binding with plasminogen and extracellular matrix components.

Intracellular generation of electronically excited states. Polymorphonuclear leukocytes challenged with a precursor of triplet acetone

Leptospira Infection Interferes with the Prothrombinase Complex Assembly during Experimental Leptospirosis.

Leptospira interrogans Lsa23 protein recruits plasminogen, factor H and C4BP from normal human serum and mediates C3b and C4b degradation.

Leptospira interrogans outer membrane protein LipL21 is a potent inhibitor of neutrophil myeloperoxidase.

Leptospira interrogans reduces fibrin clot formation by modulating human thrombin activity via exosite I.

Leptospira spp.: Novel insights into host-pathogen interactions

Leptospiral extracellular matrix adhesins as mediators of pathogen-host interactions

Lp95, a novel leptospiral protein that binds extracellular matrix components and activates e-selectin on endothelial cells.

Lsa21, a novel leptospiral protein binding adhesive matrix molecules and present during human infection.

Lsa63, a newly identified surface protein of Leptospira interrogans binds laminin and collagen IV.

Mammalian cell entry (Mce) protein of Leptospira interrogans binds extracellular matrix components, plasminogen and β2 integrin.

Modulation of Hemostatic and Inflammatory Responses by Leptospira Spp

Multifunctional and Redundant Roles of Leptospira interrogans Proteins in Bacterial-Adhesion and fibrin clotting inhibition.

Novel Leptospira interrogans protein Lsa32 is expressed during infection and binds laminin and plasminogen.

OmpL1 is an extracellular matrix- and plasminogen-interacting protein of Leptospira spp

Overexpression of a synthetic gene encoding human alpha interferon in Escherichia coli.

Plasminogen binding proteins and plasmin generation on the surface of Leptospira spp.: the contribution to the bacteria-host interactions

Proteomics as a tool to understand Leptospira physiology and virulence: Recent advances, challenges and clinical implications.

Putative outer membrane proteins of Leptospira interrogans stimulate human umbilical vein endothelial cells (HUVECS) and express during infection.

Research on bacterial virulence in the developing countries

Schiff base formation with amino acids enhances light emission and damage induced in neutrophils by phenylacetaldehyde

Schistosoma mansoni venom allergen-like protein 18 (SmVAL18) is a plasminogen-binding protein secreted during the early stages of mammalian-host infection.

Sm14 of Schistosoma mansoni in fusion with tetanus toxin fragment C induces immunoprotection against tetanus and schistosomiasis in mice.

THE PEROXIDATIVE METABOLISM OF TENOXICAM PRODUCES EXCITED SPECIES

The contribution of 700,000 ORF sequence tags to the definition of the human transcriptome.

The crystal structure of the leptospiral hypothetical protein LIC12922 reveals homology with the periplasmic chaperone SurA

The generation and utilization of a cancer-oriented representation of the human transcriptome by using expressed sequence tags

The genome sequence of the plant pathogen Xylella fastidiosa. The Xylella fastidiosa Consortium of the Organization for Nucleotide Sequencing and Analysis

The recombinant LIC10508 is a plasma fibronectin, plasminogen, fibrinogen and C4BP-binding protein of Leptospira interrogans.

The role of Lsa23 to mediate the interaction of Leptospira interrogans with the terminal complement components pathway.

Transcriptome analysis of the acoelomate human parasite Schistosoma mansoni

Whole-genome analysis of Leptospira interrogans to identify potential vaccine candidates against leptospirosis.