List of works - Hongmin Li

5'-Silylated 3'-1,2,3-triazolyl Thymidine Analogues as Inhibitors of West Nile Virus and Dengue Virus

scientific article published on 4 May 2015

A Mutational Analysis of Binding Interactions in an Antigen−Antibody Protein−Protein Complex ⬇️

scientific article published on June 2, 1998

A conformational switch high-throughput screening assay and allosteric inhibition of the flavivirus NS2B-NS3 protease

scientific article

A mutational analysis of the binding of staphylococcal enterotoxins B and C3 to the T cell receptor beta chain and major histocompatibility complex class II.

scientific article

A single point mutation changes the crystallization behavior of Mycoplasma arthritidis-derived mitogen

scientific article

Analysing the visible conformational substates of the FK506-binding protein FKBP12

scientific article

Broad Spectrum Antiviral Agent Niclosamide and Its Therapeutic Potential

scientific article published on 10 March 2020

Cisplatin protects mice from challenge of by targeting the Prp8 intein

scientific article published in 2019

Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor Proteins

scientific article published on 7 May 2015

Crystal Structure of the Mycoplasma arthritidis-Derived Mitogen in Apo Form Reveals a 3D Domain-Swapped Dimer

scientific article

Crystal structure and conformational flexibility of the unligated FK506-binding protein FKBP12.6

scientific article

Crystal structure of a T-cell receptor beta-chain complexed with a superantigen

scientific article

Crystal structure of a complete ternary complex of TCR, superantigen and peptide-MHC

scientific article

Crystal structure of an acidic neurotoxin from scorpion Buthus martensii Karsch at 1.85 A resolution

scientific article

Crystal structure of pokeweed antiviral protein with well-defined sugars from seeds at 1.8A resolution

scientific article (publication date: February 2003)

Crystal structures of T cell receptor (beta) chains related to rheumatoid arthritis

scientific article

Crystal structures of two alpha-like scorpion toxins: non-proline cis peptide bonds and implications for new binding site selectivity on the sodium channel

scientific article

Crystallization and preliminary crystallographic analyses of pokeweed antiviral protein from seeds

scientific article published on 01 January 1998

Crystallization and preliminary crystallographic analysis of Mycoplasma arthritidis-derived mitogen complexed with peptide/MHC class II antigen

scientific article published on 23 January 2004

Distinct RNA Elements Confer Specificity to Flavivirus RNA Cap Methylation Events

scientific article

Dual conformations of a T cell receptor V alpha homodimer: implications for variability in V alpha V beta domain association

scientific article

Erythrosin B is a potent and broad-spectrum orthosteric inhibitor of the flavivirus NS2B-NS3 protease

scientific article published on 27 December 2017

Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction

scientific article published on 07 July 2017

Exploring Intein Inhibition by Platinum Compounds as an Antimicrobial Strategy

scientific article published on 8 September 2016

Flavivirus RNA cap methyltransferase: structure, function, and inhibition ⬇️

scientific article published on August 1, 2010

Functional interaction of CD154 protein with α5β1 integrin is totally independent from its binding to αIIbβ3 integrin and CD40 molecules

scientific article

General Base Swap Preserves Activity and Expands Substrate Tolerance in Hedgehog Autoprocessing

scientific article published on 07 November 2019

Hectd3 promotes pathogenic Th17 lineage through Stat3 activation and Malt1 signaling in neuroinflammation

scientific article published in Nature Communications

Identification and Characterization of Novel Broad-Spectrum Inhibitors of the Flavivirus Methyltransferase

scientific article

Immunoassay Targeting Nonstructural Protein 5 To Differentiate West Nile Virus Infection from Dengue and St. Louis Encephalitis Virus Infections and from Flavivirus Vaccination

scientific article (publication date: September 2003)

Imperfect interfaces.

scientific article published in June 1998

Inexpensive electronics and software for photon statistics and correlation spectroscopy

scientific article

JMX0207, a Niclosamide Derivative with Improved Pharmacokinetics, Suppresses Zika Virus Infection Both In Vitro and In Vivo

scientific article published on 21 September 2020

Methylene blue is a potent and broad-spectrum inhibitor against Zika virus in vitro and in vivo

scientific article published on 20 October 2020

Mutagenesis, biochemical, and biophysical characterization of Mycoplasma arthritidis-derived mitogen

scientific article published on 5 June 2006

Mycobacterial DnaB helicase intein as oxidative stress sensor

scientific article published in Nature Communications

NMR and X-ray analysis of structural additivity in metal binding site-swapped hybrids of rubredoxin

scientific article

Novel Broad Spectrum Inhibitors Targeting the Flavivirus Methyltransferase

scientific article

Pfit Is a Structurally Novel Crohn's Disease-Associated Superantigen

scientific article

Refolding of a fully functional flavivirus methyltransferase revealed that S-adenosyl methionine but not S-adenosyl homocysteine is copurified with flavivirus methyltransferase

scientific article published on 11 December 2014

S-adenosyl-homocysteine is a weakly bound inhibitor for a flaviviral methyltransferase

scientific article

Selective inhibition of the West Nile virus methyltransferase by nucleoside analogs

scientific article published on 22 December 2012

Separate molecules of West Nile virus methyltransferase can independently catalyze the N7 and 2′-O methylations of viral RNA cap

scientific article

Spliceosomal Prp8 intein at the crossroads of protein and RNA splicing

scientific article published on 10 October 2019

Structural and Functional Analyses of a Conserved Hydrophobic Pocket of Flavivirus Methyltransferase

scientific article

Structural basis for the binding of an immunodominant peptide from myelin basic protein in different registers by two HLA-DR2 proteins

scientific article

Structural basis of conformational transitions in the active site and 80′s loop in the FK506-binding protein FKBP12

scientific article

Structure and Function of Flavivirus NS5 Methyltransferase

scientific article (publication date: April 2007)

Structure of an engineered intein reveals thiazoline ring and provides mechanistic insight

scientific article published on 08 January 2019

Structure of the Vdelta domain of a human gammadelta T-cell antigen receptor

scientific article

Structure-function studies of T-cell receptor-superantigen interactions.

scientific article published in June 1998

Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes

scientific article

Targeting Crucial Host Factors of SARS-CoV-2

scientific article published on 28 October 2020

The HECTD3 E3 ubiquitin ligase facilitates cancer cell survival by promoting K63-linked polyubiquitination of caspase-8

scientific article

The HECTD3 E3 ubiquitin ligase suppresses cisplatin-induced apoptosis via stabilizing MALT1.

scientific article published on January 2013

The flavivirus protease as a target for drug discovery

scientific article

The human polymeric immunoglobulin receptor binds to Streptococcus pneumoniae via domains 3 and 4.

scientific article

The structural basis of T cell activation by superantigens.

scientific article

The structure of the Candida albicans Ess1 prolyl isomerase reveals a well-ordered linker that restricts domain mobility

scientific article published on April 2005

Three-dimensional structure of H-2Dd complexed with an immunodominant peptide from human immunodeficiency virus envelope glycoprotein 120

scientific article

Three-dimensional structure of human gamma -glutamyl hydrolase. A class I glatamine amidotransferase adapted for a complex substate

scientific article

Three-dimensional structures of the free and antigen-bound Fab from monoclonal antilysozyme antibody HyHEL-63(,)

scientific article

Transcription Factor Bcl11b Controls Identity and Function of Mature Type 2 Innate Lymphoid Cells

scientific article

West Nile Virus 5'-Cap Structure Is Formed by Sequential Guanine N-7 and Ribose 2'-O Methylations by Nonstructural Protein 5

scientific article

West Nile Virus Methyltransferase Catalyzes Two Methylations of the Viral RNA Cap through a Substrate-Repositioning Mechanism

scientific article

X-ray snapshots of the maturation of an antibody response to a protein antigen ⬇️

scientific article (publication date: June 2003)

Zinc Induces Dimerization of the Class II Major Histocompatibility Complex Molecule That Leads to Cooperative Binding to a Superantigen

scientific article

Zinc inhibits Hedgehog autoprocessing: linking zinc deficiency with Hedgehog activation

scientific article published on 18 March 2015

List of works by Hongmin Li

5'-Silylated 3'-1,2,3-triazolyl Thymidine Analogues as Inhibitors of West Nile Virus and Dengue Virus

A Mutational Analysis of Binding Interactions in an Antigen−Antibody Protein−Protein Complex ⬇️

A conformational switch high-throughput screening assay and allosteric inhibition of the flavivirus NS2B-NS3 protease

A mutational analysis of the binding of staphylococcal enterotoxins B and C3 to the T cell receptor beta chain and major histocompatibility complex class II.

A single point mutation changes the crystallization behavior of Mycoplasma arthritidis-derived mitogen

Analysing the visible conformational substates of the FK506-binding protein FKBP12

Broad Spectrum Antiviral Agent Niclosamide and Its Therapeutic Potential

Cisplatin protects mice from challenge of by targeting the Prp8 intein

Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor Proteins

Crystal Structure of the Mycoplasma arthritidis-Derived Mitogen in Apo Form Reveals a 3D Domain-Swapped Dimer

Crystal structure and conformational flexibility of the unligated FK506-binding protein FKBP12.6

Crystal structure of a T-cell receptor beta-chain complexed with a superantigen

Crystal structure of a complete ternary complex of TCR, superantigen and peptide-MHC

Crystal structure of an acidic neurotoxin from scorpion Buthus martensii Karsch at 1.85 A resolution

Crystal structure of pokeweed antiviral protein with well-defined sugars from seeds at 1.8A resolution

Crystal structures of T cell receptor (beta) chains related to rheumatoid arthritis

Crystal structures of two alpha-like scorpion toxins: non-proline cis peptide bonds and implications for new binding site selectivity on the sodium channel

Crystallization and preliminary crystallographic analyses of pokeweed antiviral protein from seeds

Crystallization and preliminary crystallographic analysis of Mycoplasma arthritidis-derived mitogen complexed with peptide/MHC class II antigen

Distinct RNA Elements Confer Specificity to Flavivirus RNA Cap Methylation Events

Dual conformations of a T cell receptor V alpha homodimer: implications for variability in V alpha V beta domain association

Erythrosin B is a potent and broad-spectrum orthosteric inhibitor of the flavivirus NS2B-NS3 protease

Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction

Exploring Intein Inhibition by Platinum Compounds as an Antimicrobial Strategy

Flavivirus RNA cap methyltransferase: structure, function, and inhibition ⬇️

Functional interaction of CD154 protein with α5β1 integrin is totally independent from its binding to αIIbβ3 integrin and CD40 molecules

General Base Swap Preserves Activity and Expands Substrate Tolerance in Hedgehog Autoprocessing

Hectd3 promotes pathogenic Th17 lineage through Stat3 activation and Malt1 signaling in neuroinflammation

Identification and Characterization of Novel Broad-Spectrum Inhibitors of the Flavivirus Methyltransferase

Immunoassay Targeting Nonstructural Protein 5 To Differentiate West Nile Virus Infection from Dengue and St. Louis Encephalitis Virus Infections and from Flavivirus Vaccination

Imperfect interfaces.

Inexpensive electronics and software for photon statistics and correlation spectroscopy

JMX0207, a Niclosamide Derivative with Improved Pharmacokinetics, Suppresses Zika Virus Infection Both In Vitro and In Vivo

Methylene blue is a potent and broad-spectrum inhibitor against Zika virus in vitro and in vivo

Mutagenesis, biochemical, and biophysical characterization of Mycoplasma arthritidis-derived mitogen

Mycobacterial DnaB helicase intein as oxidative stress sensor

NMR and X-ray analysis of structural additivity in metal binding site-swapped hybrids of rubredoxin

Novel Broad Spectrum Inhibitors Targeting the Flavivirus Methyltransferase

Pfit Is a Structurally Novel Crohn's Disease-Associated Superantigen

Refolding of a fully functional flavivirus methyltransferase revealed that S-adenosyl methionine but not S-adenosyl homocysteine is copurified with flavivirus methyltransferase

S-adenosyl-homocysteine is a weakly bound inhibitor for a flaviviral methyltransferase

Selective inhibition of the West Nile virus methyltransferase by nucleoside analogs

Separate molecules of West Nile virus methyltransferase can independently catalyze the N7 and 2′-O methylations of viral RNA cap

Spliceosomal Prp8 intein at the crossroads of protein and RNA splicing

Structural and Functional Analyses of a Conserved Hydrophobic Pocket of Flavivirus Methyltransferase

Structural basis for the binding of an immunodominant peptide from myelin basic protein in different registers by two HLA-DR2 proteins

Structural basis of conformational transitions in the active site and 80′s loop in the FK506-binding protein FKBP12

Structure and Function of Flavivirus NS5 Methyltransferase

Structure of an engineered intein reveals thiazoline ring and provides mechanistic insight

Structure of the Vdelta domain of a human gammadelta T-cell antigen receptor

Structure-function studies of T-cell receptor-superantigen interactions.

Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes

Targeting Crucial Host Factors of SARS-CoV-2

The HECTD3 E3 ubiquitin ligase facilitates cancer cell survival by promoting K63-linked polyubiquitination of caspase-8

The HECTD3 E3 ubiquitin ligase suppresses cisplatin-induced apoptosis via stabilizing MALT1.

The flavivirus protease as a target for drug discovery

The human polymeric immunoglobulin receptor binds to Streptococcus pneumoniae via domains 3 and 4.

The structural basis of T cell activation by superantigens.

The structure of the Candida albicans Ess1 prolyl isomerase reveals a well-ordered linker that restricts domain mobility

Three-dimensional structure of H-2Dd complexed with an immunodominant peptide from human immunodeficiency virus envelope glycoprotein 120

Three-dimensional structure of human gamma -glutamyl hydrolase. A class I glatamine amidotransferase adapted for a complex substate

Three-dimensional structures of the free and antigen-bound Fab from monoclonal antilysozyme antibody HyHEL-63(,)

Transcription Factor Bcl11b Controls Identity and Function of Mature Type 2 Innate Lymphoid Cells

West Nile Virus 5'-Cap Structure Is Formed by Sequential Guanine N-7 and Ribose 2'-O Methylations by Nonstructural Protein 5

West Nile Virus Methyltransferase Catalyzes Two Methylations of the Viral RNA Cap through a Substrate-Repositioning Mechanism

X-ray snapshots of the maturation of an antibody response to a protein antigen ⬇️

Zinc Induces Dimerization of the Class II Major Histocompatibility Complex Molecule That Leads to Cooperative Binding to a Superantigen

Zinc inhibits Hedgehog autoprocessing: linking zinc deficiency with Hedgehog activation