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List of works by Paul R Young

A broadly protective antibody that targets the flavivirus NS1 protein

scientific article published on 01 January 2021

A chimeric dengue virus vaccine candidate delivered by high density microarray patches protects against infection in mice

scientific article published on 07 May 2021

A dual-purpose synthetic colloidal platform for protease mapping: substrate profiling for Dengue and West Nile virus proteases

scientific article

A portable approach for the surveillance of dengue virus-infected mosquitoes

scientific article published on 3 April 2012

A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses

scientific article published on 01 June 2021

A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses

scientific article published on 08 June 2021

Activity of recombinant dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitors.

scientific article published on October 2001

Assessing the potential of unmanned aerial vehicle spraying of aqueous ozone as an outdoor disinfectant for SARS-CoV-2

scientific article published on 26 February 2021

Biology and evolution of the endogenous koala retrovirus

scientific article

Catalytically active Dengue virus NS3 protease forms aggregates that are separable by size exclusion chromatography.

scientific article published on July 2002

Characterization of Nugget virus, a serotype of the Kemerovo group of orbiviruses ⬇️

scientific article published on February 1, 1984

Colourimetric PCR-based detection of monodon baculovirus in whole Penaeus monodon postlarvae.

scientific article published in September 1998

Comparison between polyethylene glycol and zwitterionic polymers as antifouling coatings on wearable devices for selective antigen capture from biological tissue

scientific article published on 7 December 2015

Dengue

article

Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity

scientific article published on September 2015

Determination of the disulfide bond arrangement of dengue virus NS1 protein

scientific article published on 23 February 2004

Discovery of a novel retrovirus sequence in an Australian native rodent (Melomys burtoni): a putative link between gibbon ape leukemia virus and koala retrovirus ⬇️

scientific article

Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency

scientific article

Enhancement of immunoblot staining using a mixed chromogenic substrate

scientific article published on 01 July 1989

Enzymatic characterization and homology model of a catalytically active recombinant West Nile virus NS3 protease

scientific article published on 18 August 2004

Evaluation of direct versus multi-layer passivation and capture chemistries for nanoparticle-based biosensor applications

scientific article published on 28 September 2014

Expression of recombinant West Nile virus prM protein fused to an affinity tag for use as a diagnostic antigen.

scientific article published on 27 April 2011

Fine structure analysis of Pichinde virus nucleocapsids.

scientific article

Generation and characterization of proteolytically active and highly stable truncated and full-length recombinant West Nile virus NS3.

scientific article published on 7 November 2006

Hepatitis B surface antigen polypeptide micelles from antigen expressed in Saccharomyces cerevisiae

scientific article published on 01 August 1986

High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever

scientific article (publication date: 15 October 2002)

Histidine protonation and the activation of viral fusion proteins

scientific article

Homology model of the dengue 2 virus NS3 protease: putative interactions with both substrate and NS2B cofactor.

scientific article published on May 1999

Identification of novel target sites and an inhibitor of the dengue virus E protein

scientific article published on 25 February 2009

Immunoaffinity purification of native dimer forms of the flavivirus non-structural glycoprotein, NS1.

scientific article published on December 1990

Immunolocalization of the dengue virus nonstructural glycoprotein NS1 suggests a role in viral RNA replication

scientific article (publication date: June 1996)

Improved membrane preservation of flavivirus-infected cells with cryosectioning.

scientific article published on January 1996

In silico screening of small molecule libraries using the dengue virus envelope E protein has identified compounds with antiviral activity against multiple flaviviruses.

scientific article

Insights to substrate binding and processing by West Nile Virus NS3 protease through combined modeling, protease mutagenesis, and kinetic studies

scientific article published on 19 October 2006

Kinetics of plasma viremia and soluble nonstructural protein 1 concentrations in dengue: differential effects according to serotype and immune status

scientific article

Last 20 aa of the West Nile virus NS1' protein are responsible for its retention in cells and the formation of unique heat-stable dimers

scientific article

Maternal antibody and viral factors in the pathogenesis of dengue virus in infants

scientific article

Maturation of the dengue-2 virus NS1 protein in insect cells: effects of downstream NS2A sequences on baculovirus-expressed gene constructs.

scientific article published on April 1995

Modified influenza virosomes: recent advances and potential in gene delivery.

scientific article

Modular alpha-helical mimetics with antiviral activity against respiratory syncitial virus.

scientific article

Mutagenesis of the West Nile virus NS2B cofactor domain reveals two regions essential for protease activity

scientific article

Potent cationic inhibitors of West Nile virus NS2B/NS3 protease with serum stability, cell permeability and antiviral activity

scientific article published on 26 August 2008

Preparation of hepatitis B polypeptide micelles from human carrier plasma

scientific article published on 01 April 1982

Prevalence of koala retrovirus in geographically diverse populations in Australia.

scientific article

Production of dimer-specific and dengue virus group cross-reactive mouse monoclonal antibodies to the dengue 2 virus non-structural glycoprotein NS1

scientific article published on April 1, 1991

Production of the baculovirus-expressed dengue virus glycoprotein NS1 can be improved dramatically with optimised regimes for fed-batch cultures and the addition of the insect moulting hormone, 20-Hydroxyecdysone

scientific article published on August 2002

Real-time reverse transcriptase PCR for the endogenous koala retrovirus reveals an association between plasma viral load and neoplastic disease in koalas.

scientific article published in March 2005

Residues in domain III of the dengue virus envelope glycoprotein involved in cell-surface glycosaminoglycan binding ⬇️

scientific article published on September 28, 2011

Retroviral invasion of the koala genome

scientific article published in July 2006

Ribonucleoprotein complexes associated with virions of Pichinde virus and Pichinde virus-infected cells.

scientific article published in January 1986

Save the microbes to save the planet. A call to action of the International Union of the Microbiological Societies (IUMS)

scientific article published in 2023

Sequence of the dengue virus type 2 (strain PR-159) NS1 gene and comparison with its vaccine derivative

scientific article

Site-directed mutagenesis and kinetic studies of the West Nile Virus NS3 protease identify key enzyme-substrate interactions.

scientific article published on 19 October 2004

Stable high-level expression of heterologous genes in vitro and in vivo by noncytopathic DNA-based Kunjin virus replicon vectors

scientific article (publication date: May 2000)

Structural characterization of respiratory syncytial virus fusion inhibitor escape mutants: homology model of the F protein and a syncytium formation assay

scientific article published in July 2003

Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation

scientific article

Structure of the dengue virus glycoprotein non-structural protein 1 by electron microscopy and single-particle analysis

scientific article published on 13 January 2012

Surface modified microprojection arrays for the selective extraction of the dengue virus NS1 protein as a marker for disease

scientific article published on 12 March 2012

SwarmPS: rapid, semi-automated single particle selection software

scientific article published on 22 May 2006

The Role of histidine residues in low-pH-mediated viral membrane fusion

scientific article published on October 2006

The diagnostic sensitivity of dengue rapid test assays is significantly enhanced by using a combined antigen and antibody testing approach

scientific article

The discriminative bilateral filter: an enhanced denoising filter for electron microscopy data

scientific article

The flavivirus NS1 protein: molecular and structural biology, immunology, role in pathogenesis and application as a diagnostic biomarker

scientific article published on 21 March 2013

The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity

scientific article published on September 2010

The isolation of recombinants between related orbiviruses

scientific article published on November 1, 1978

Therapeutics for dengue: recommendations for design and conduct of early-phase clinical trials

scientific article

Use of recombinant fusion proteins and monoclonal antibodies to define linear and discontinuous antigenic sites on the dengue virus envelope glycoprotein

scientific article published on April 1, 1992

Variation among new and old world arenaviruses

scientific article published on 01 January 1984

Wolbachia-mediated resistance to dengue virus infection and death at the cellular level

scientific article

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