Search filters

List of works by Margarita López-Trascasa

A new case of homozygous C1-inhibitor deficiency suggests a role for Arg378 in the control of kinin pathway activation

scientific article published on 01 December 2010

A novel method for direct measurement of complement convertases activity in human serum.

scientific article

A novel nonsense mutation at Glu-631 in a Spanish family with complement component 7 deficiency

scientific article published on 01 January 1999

A possible common pathogenesis of the mesangial IgA glomerulonephritis in patients with Berger's disease and Schönlein-Henoch syndrome

scientific article published on 01 January 1980

Abstracts from the 10th C1-inhibitor deficiency workshop.

scientific article

Acquired Angioedema With Anti-C1-inhibitor Autoantibodies During Assisted Reproduction Techniques

scientific article published in January 2018

Acquired C1 esterase inhibitor deficiency

scientific article published on 01 November 2000

Acquired partial lipodystrophy and C3 glomerulopathy: Dysregulation of the complement system as a common pathogenic mechanism.

scientific article published on 23 December 2017

An ELISA assay with two monoclonal antibodies allows the estimation of free factor H and identifies patients with acquired deficiency of this complement regulator

scientific article

Analysis of SERPING1 expression on hereditary angioedema patients: quantitative analysis of full-length and exon 3 splicing variants

scientific article

Angioedema and transient acquired C1 inhibitor functional deficiency in HIV infection: case report

article

Anti-IgA antibodies in selective IgA deficiency and in primary immunodeficient patients treated with gamma-globulin

scientific article published on 01 May 1988

Anti-factor H antibody affecting factor H cofactor activity in a patient with dense deposit disease.

scientific article published on 15 March 2012

Anticardiolipin antibodies in patients with primary immunodeficiency diseases.

scientific article

Association of anti-C1 inhibitor and anti-protein S antibodies in a patient with primary antiphospholipid syndrome

scientific article published on 01 February 2009

Atypical hemolytic uremic syndrome in the Tunisian population.

scientific article

Atypical hemolytic uremic syndrome-associated variants and autoantibodies impair binding of factor h and factor h-related protein 1 to pentraxin 3.

scientific article

Autoantibodies Against Perilipin 1 as a Cause of Acquired Generalized Lipodystrophy

scientific article published on 19 September 2018

Autoantibodies against alternative complement pathway proteins in renal pathologies.

scientific article published on 3 June 2016

Autoantibodies against complement receptor 1 (CD35) in SLE, liver cirrhosis and HIV-infected patients

scientific article published on 01 January 2003

Autoantibodies in patients with IgA and IgG2 deficiencies

scientific article published on 01 April 1991

Autoantibodies to complement components in C3 glomerulopathy and atypical hemolytic uremic syndrome.

scientific article

C1 inhibitor function using contact-phase proteases as target: evaluation of an innovative assay.

scientific article published on 26 May 2015

C4 deficiency in chronic angioedema

scientific article published on 01 November 2001

C5 complement deficiency in a Spanish family. Molecular characterization of the double mutation responsible for the defect

scientific article published on 01 January 2005

C7 deficiency and meningococcal infection susceptibility in two spanish families.

scientific article

Case report: lupus nephritis with autoantibodies to complement alternative pathway proteins and C3 gene mutation

scientific article published on 30 March 2015

Cell surface molecules related to factor J in human lymphoid cells and cell lines.

scientific article published on August 1995

Characterization of complement factor H-related (CFHR) proteins in plasma reveals novel genetic variations of CFHR1 associated with atypical hemolytic uremic syndrome

scientific article

Clinical Pattern and Acute and Long-term Management of Hereditary Angioedema Due to C1-Esterase Inhibitor Deficiency

scientific article published on January 2015

Clinical, biochemical, and genetic characterization of type III hereditary angioedema in 13 Northwest Spanish families.

scientific article published on 27 June 2012

Clustering of missense mutations in the C-terminal region of factor H in atypical hemolytic uremic syndrome.

scientific article

Combined total deficiency of C7 and C4B with systemic lupus erythematosus (SLE)

scientific article published on 01 March 1992

Common and rare genetic variants of complement components in human disease

scientific article published on 18 June 2018

Complement Study Versus CINH Gene Testing for the Diagnosis of Type I Hereditary Angioedema in Children

scientific article published on 10 December 2015

Complement as a diagnostic tool in immunopathology.

scientific article published on 29 December 2017

Complement component C7 deficiency in a Spanish family

article

Complement component C7 deficiency in two Spanish families

article

Complement factor H variants I890 and L1007 while commonly associated with atypical hemolytic uremic syndrome are polymorphisms with no functional significance

scientific article

Complement factor H, FHR-3 and FHR-1 variants associate in an extended haplotype conferring increased risk of atypical hemolytic uremic syndrome

scientific article

Complement factor I deficiency associated with recurrent meningitis coinciding with menstruation

scientific article (publication date: November 2001)

Complement mutations in diacylglycerol kinase-ε-associated atypical hemolytic uremic syndrome

scientific article

Consensus statement on the diagnosis, management, and treatment of angioedema mediated by bradykinin. Part I. Classification, epidemiology, pathophysiology, genetics, clinical symptoms, and diagnosis

scientific article

Consensus statement on the diagnosis, management, and treatment of angioedema mediated by bradykinin. Part II. Treatment, follow-up, and special situations.

scientific article published on January 2011

Detection of C1 inhibitor (SERPING1/C1NH) mutations in exon 8 in patients with hereditary angioedema: evidence for 10 novel mutations

scientific article published on 01 November 2002

Determination of C3 nephritic factor activity by a microassay based on the peroxidase-like activity of the heme group.

scientific article published in December 1990

Disease-modifying factors in hereditary angioedema: an RNA expression-based screening.

scientific article published on 20 May 2013

Eculizumab in dense-deposit disease after renal transplantation

scientific article published on 08 June 2014

Eculizumab in the Treatment of Atypical Hemolytic Uremic Syndrome in Infants ⬇️

scientific article published on December 23, 2011

Eculizumab long-term therapy for pediatric renal transplant in aHUS with CFH/CFHR1 hybrid gene

scientific article

Effects of disodium cromoglycate and antihistamines in acute serum sickness of rabbits

scientific article published on January 1, 1977

Elevated factor H-related protein 1 and factor H pathogenic variants decrease complement regulation in IgA nephropathy.

scientific article published on 18 June 2017

Elevated factor J levels in synovial fluid from patients with inflammatory arthropathies

scientific article published on 01 December 1997

Expression of the SERPING1 gene is not regulated by promoter hypermethylation in peripheral blood mononuclear cells from patients with hereditary angioedema due to C1-inhibitor deficiency.

scientific article

Extravascular hemolysis and complement consumption in Paroxysmal Nocturnal Hemoglobinuria patients undergoing eculizumab treatment

scientific article published on 13 September 2016

Factor J, a human inhibitor of complement C1, is a cationic, highly glycosylated protein

scientific article published on 01 October 1994

Factor J, an inhibitor of the classical and alternative complement pathway, does not inhibit esterolysis by factor D

scientific article published on 01 July 1996

Factor J, an inhibitor of the complement classical pathway: the quantitation by an ELISA inhibition assay in normal human serum

scientific article published on 01 June 1994

Factor J: isolation and characterization of a new polypeptide inhibitor of complement C1

scientific article published on 01 September 1989

Familial incidence of C3 nephritic factor

scientific article published on 01 January 1991

First case of homozygous C1 inhibitor deficiency

scientific article published on 18 September 2006

Functional analysis in serum from atypical Hemolytic Uremic Syndrome patients reveals impaired protection of host cells associated with mutations in factor H.

scientific article

Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome

scientific article

HIV-1 induced generation of C5a attracts immature dendriticcells and promotes infection of autologous T cells.

scientific article

Hereditary angioedema caused by the p.Thr309Lys mutation in the F12 gene: a multifactorial disease.

scientific article

Hereditary angioedema with F12 mutation: factors modifying the clinical phenotype

scientific article published on 10 October 2014

Hereditary angioedema: the mutation spectrum of SERPING1/C1NH in a large Spanish cohort.

scientific article published in August 2005

Heterogeneity but individual constancy of epitopes, isotypes and avidity of factor H autoantibodies in atypical hemolytic uremic syndrome

scientific article

High prevalence of anti-C1q antibodies in biopsy-proven active lupus nephritis

scientific article published on 28 July 2006

Human plasma C3 is essential for the development of memory B, but not T, lymphocytes.

scientific article

Incidence of selective IgG2 deficiency in patients with vasculitis

scientific article published on 01 November 1989

Insights into hemolytic uremic syndrome: segregation of three independent predisposition factors in a large, multiple affected pedigree

scientific article

Interaction between C3 nephritic factor and erythrocyte membranes. Presence of nephritic factor in patients' erythrocytes

scientific article published on 01 January 1988

Interaction of C3 nephritic factor (NEF) with erythrocyte membranes complement-independent binding to sheep and patients' erythrocytes

scientific article published on 01 January 1991

Laboratory guidelines for the diagnosis and follow-up of patients with monoclonal gammopathies

scientific article

Laboratory guidelines for the diagnosis of patients with cryoglobulinaemic syndrome

scientific article published on 19 December 2018

Mechanisms Involved in Hypersensitivity Reactions to Polysulfone Hemodialysis Membranes

scientific article

Modulation of C4b-binding protein isoforms during the acute phase response caused by orthopedic surgery.

scientific article published in January 1997

Molecular characterization of Complement Factor I deficiency in two Spanish families

scientific article published on 28 March 2008

Molecular defects of the C7 gene in two patients with complement C7 deficiency.

scientific article

Multimarker risk stratification approach at multiple sclerosis onset.

scientific article published on 31 May 2017

Mutations in proteins of the alternative pathway of complement and the pathogenesis of atypical hemolytic uremic syndrome

scientific article

Nephritic Factors: An Overview of Classification, Diagnostic Tools and Clinical Associations

scientific article published on 24 April 2019

Polyclonal autoantibodies against C1 inhibitor in a case of acquired angioedema

scientific article published on 01 June 2002

Predisposition to atypical hemolytic uremic syndrome involves the concurrence of different susceptibility alleles in the regulators of complement activation gene cluster in 1q32.

scientific article

Quantitation of C2 by rocket immunoelectrophoresis in 120 pathological sera

scientific article published on 01 October 1981

Receptors for complement components in inflammation

scientific article published on 01 August 1983

Requirements for the production of high-titre C3 nephritic factor (NEF) antibody in vitro

scientific article published on 01 June 1992

Rothmund-Thomson syndrome and glomerulonephritis in a homozygous C1q-deficient patient due to a Gly164Ser C1qC mutation

scientific article published on 24 October 2013

SERPING1 mutation update: Mutation spectrum and C1 Inhibitor phenotypes

scientific article published on 22 October 2019

SERPING1 mutations in 59 families with hereditary angioedema

scientific article published on August 23, 2011

Self-Damage Caused by Dysregulation of the Complement Alternative Pathway: Relevance of the Factor H Protein Family

scientific article published on 12 July 2018

Sensitive and specific assays for C3 nephritic factors clarify mechanisms underlying complement dysregulation

scientific article published on August 2012

Serum complexes between C1INH and C1INH autoantibodies for the diagnosis of acquired angioedema

scientific article published on 17 September 2019

Serum properdin consumption as a biomarker of C5 convertase dysregulation in C3 glomerulopathy

scientific article

Structural and functional characterization of factor H mutations associated with atypical hemolytic uremic syndrome

scientific article

Successful renal transplantation in a patient with atypical hemolytic uremic syndrome carrying mutations in both factor I and MCP.

scientific article

Successful use of rituximab in acquired C1 inhibitor deficiency secondary to Sjogren's syndrome

scientific article published on 01 March 2008

Targeted next-generation sequencing for the molecular diagnosis of hereditary angioedema due to C1-inhibitor deficiency

scientific article published on 16 May 2018

Testing the Activity of Complement Convertases in Serum/Plasma for Diagnosis of C4NeF-Mediated C3 Glomerulonephritis.

scientific article published on 05 May 2016

The inhibitory effect of factor J on the alternative complement pathway

scientific article published on 01 October 1994

The mechanism of loss of CR1 during maturation of erythrocytes is different between factor I deficient patients and healthy donors

scientific article published on 01 September 2002

The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome.

scientific article

Treatment of primary immunodeficiencies with intravenous gamma globulin

scientific article published on 01 December 1987

Utility of oligoclonal IgG band detection for MS diagnosis in daily clinical practice.

scientific article published on 17 June 2011

[Cellular receptors for complement components: repertory and functions]

scientific article published on 01 March 1982

[Cold-induced urticaria with activity of C3 nephritic factor]

scientific article published on 01 June 1991

[Deficiencies of C1 inhibitor: hereditary and acquired angioedema]

scientific article published on 01 March 1996

[Genetic factors in the haemolytic uremic syndrome. Diagnostic and therapeutic implications]

scientific article published on 01 January 2004

[Hereditary angioedema of delayed onset]

scientific article published on 01 September 2004

[New indications for gamma globulins]

scientific article published on 01 June 1992

Paulina is supported by:

About Paulina

Help