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List of works by Jérome Fagart

11beta-hydroxyprogesterone acts as a mineralocorticoid agonist in stimulating Na+ absorption in mammalian principal cortical collecting duct cells.

scientific article published in December 2002

A New Strategy for Selective Targeting of Progesterone Receptor With Passive Antagonists ⬇️

scientific article published on April 11, 2013

A new model for 20-hydroxyecdysone and dibenzoylhydrazine binding: a homology modeling and docking approach

scientific article published in June 2000

A single amino acid mutation of ala-773 in the mineralocorticoid receptor confers agonist properties to 11beta-substituted spirolactones

scientific article published on 01 October 2000

A structural explanation of the effects of dissociated glucocorticoids on glucocorticoid receptor transactivation.

scientific article

ATG7 and ATG9A loss-of-function variants trigger autophagy impairment and ovarian failure

scientific article published on 19 September 2018

Agonists and antagonists of mineralocorticoids. The relation between structure and activity

scientific article

Antagonism in the human mineralocorticoid receptor.

scientific article

Antagonistic effects of finerenone and spironolactone on the aldosterone-regulated transcriptome of human kidney cells

scientific article published on 01 February 2021

Characterization of seven novel mutations on the HEXB gene in French Sandhoff patients

scientific article published on 06 October 2012

Cistrome of the aldosterone-activated mineralocorticoid receptor in human renal cells.

scientific article published on 8 June 2015

Corticosteroid receptors adopt distinct cyclical transcriptional signatures

scientific article published on 07 May 2018

Crucial role of the H11-H12 loop in stabilizing the active conformation of the human mineralocorticoid receptor

scientific article (publication date: August 2000)

Crystal structure of a mutant mineralocorticoid receptor responsible for hypertension.

scientific article

Familial Multiplicity of Estrogen Insensitivity Associated With a Loss-of-Function ESR1 Mutation

scientific article

Finerenone Impedes Aldosterone-dependent Nuclear Import of the Mineralocorticoid Receptor and Prevents Genomic Recruitment of Steroid Receptor Coactivator-1.

scientific article published on 22 July 2015

Folding Requirements of the Ligand-Binding Domain of the Human Mineralocorticoid Receptor ⬇️

scientific article published on June 1, 1998

Glucocorticoid metabolism by 11-beta hydroxysteroid dehydrogenase type 2 modulates human mineralocorticoid receptor transactivation activity.

scientific article published on February 2003

HuR-Dependent Editing of a New Mineralocorticoid Receptor Splice Variant Reveals an Osmoregulatory Loop for Sodium Homeostasis

scientific article

Identification of Multiple Gene Mutations Accounts for a new Genetic Architecture of Primary Ovarian Insufficiency.

scientific article published on 7 September 2016

Identification of Periplakin as a New Target for Autoreactivity in Idiopathic Pulmonary Fibrosis ⬇️

scientific article published on October 8, 2010

Ligand-induced conformational change in the human mineralocorticoid receptor occurs within its hetero-oligomeric structure.

scientific article

Mechanistic aspects of mineralocorticoid receptor activation

scientific article (publication date: April 2000)

Mineralocorticoid receptor mutations are the principal cause of renal type 1 pseudohypoaldosteronism

scientific article published on 01 January 2007

Mineralocorticoid receptor mutations differentially affect individual gene expression profiles in pseudohypoaldosteronism type 1.

scientific article

Molecular determinants of the recognition of ulipristal acetate by oxo-steroid receptors

scientific article

Nestorone® as a Novel Progestin for Nonoral Contraception: Structure-Activity Relationships and Brain Metabolism Studies.

scientific article published on 8 November 2016

New steroidal diazo ketones as potential photoaffinity labeling reagents for the mineralocorticoid receptor: synthesis and biological activities.

scientific article published on July 1996

Photoaffinity labelling of the human mineralocorticoid receptor with steroids having a reactive group at position 3, 18 or 21.

scientific article published in October 1998

Properties of polyglutamine expansion in vitro and in a cellular model for Huntington's disease.

scientific article

RNA-binding protein HuR enhances mineralocorticoid signaling in renal KC3AC1 cells under hypotonicity.

scientific article

Structural determinants of ligand binding to the mineralocorticoid receptor.

scientific article published on 25 July 2011

Sulfhydryl groups are involved in the binding of agonists and antagonists to the human mineralocorticoid receptor.

scientific article published in March 1996

The Met852 residue is a key organizer of the ligand-binding cavity of the human mineralocorticoid receptor.

scientific article

The severe form of hypertension caused by the activating S810L mutation in the mineralocorticoid receptor is cortisone related.

scientific article published in February 2003

The synthetic androgen methyltrienolone (r1881) acts as a potent antagonist of the mineralocorticoid receptor.

scientific article published on 14 November 2006

Three Novel Heterozygous Point Mutations of NR3C1 Causing Glucocorticoid Resistance

scientific article published on 11 May 2016

[Corticosteroid hormones: mechanisms involved in the recognition of aldosterone by mineralocorticoid receptors]

scientific article published on 01 January 1999

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