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List of works by Laurence Lafanechère

A quantitative proteomic analysis of cofilin phosphorylation in myeloid cells and its modulation using the LIM kinase inhibitor Pyr1

scientific article published in PLoS ONE

A revised nomenclature for the human and rodent alpha-tubulin gene family

scientific article published in June 2007

Acacetin and chrysin, two polyphenolic compounds, alleviate telomeric position effect in human cells.

scientific article published on 20 August 2013

Antitumor activity of pyridocarbazole and benzopyridoindole derivatives that inhibit protein kinase CK2

scientific article

Azaindole derivatives are inhibitors of microtubule dynamics, with anti-cancer and anti-angiogenic activities.

scientific article

BCIRG 001 molecular analysis: prognostic factors in node-positive breast cancer patients receiving adjuvant chemotherapy.

scientific article published on 24 June 2010

Benzo[e]pyridoindoles, novel inhibitors of the aurora kinases.

scientific article

Control-Plate Regression (CPR) Normalization for High-Throughput Screens with Many Active Features.

scientific article

Expanding the chemical diversity of CK2 inhibitors.

scientific article

Expression of class III {beta}-tubulin is predictive of patient outcome in patients with non-small cell lung cancer receiving vinorelbine-based chemotherapy.

scientific article published in August 2005

High-content screening for the discovery of pharmacological compounds: advantages, challenges and potential benefits of recent technological developments.

scientific article published on 09 January 2010

Identification of proteins binding the native tubulin dimer

scientific article

Identification of pyrrolopyrimidine derivative PP-13 as a novel microtubule-destabilizing agent with promising anticancer properties

scientific article published on 31 August 2017

Improving detection of rare biological events in high-throughput screens

scientific article

Intensity quantile estimation and mapping--a novel algorithm for the correction of image non-uniformity bias in HCS data.

scientific article

LIM Kinase Inhibitor Pyr1 Reduces the Growth and Metastatic Load of Breast Cancers

scientific article published on 23 May 2016

LIM kinases: cofilin and beyond.

scientific article published on 9 April 2017

LIMK Regulates Tumor-Cell Invasion and Matrix Degradation Through Tyrosine Phosphorylation of MT1-MMP.

scientific article published on 27 April 2016

LKB1 specifies neural crest cell fates through pyruvate-alanine cycling

scientific article published on 17 July 2019

Les années 2010

Miniaturization and validation of a sensitive multiparametric cell-based assay for the concomitant detection of microtubule-destabilizing and microtubule-stabilizing agents

scientific article published on 28 April 2006

New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights

scientific article

Novel in silico-designed estradiol analogues are cytotoxic to a multidrug-resistant cell line at nanomolar concentrations

scientific article

Novel synthetic pharmacophores inducing a stabilization of cellular microtubules.

scientific article published in January 2015

Parthenolide inhibits tubulin carboxypeptidase activity

scientific article published on 01 April 2007

Pharmacological inhibition of LIM kinase stabilizes microtubules and inhibits neoplastic growth

scientific article

Phenotypic screens or one stone to kill two birds: discover the target and its pharmacological regulator

scientific article

Preliminary crystallographic study of a complex formed between the alpha/beta-tubulin heterodimer and the neuronal growth-associated protein SCG10

scientific article published on 01 August 2000

Preparation of pure tyrosinated or detyrosinated tubulin isoforms

scientific article published on 01 January 2011

Pyr1-Mediated Pharmacological Inhibition of LIM Kinase Restores Synaptic Plasticity and Normal Behavior in a Mouse Model of Schizophrenia

scientific article published on 12 March 2021

Salicylaldehyde derivatives as new protein kinase CK2 inhibitors.

scientific article

Separation of tubulin subunits under nondenaturing conditions.

scientific article published in June 1998

Single assay-wide variance experimental (SAVE) design for high-throughput screening

scientific article

Specific Targeting of Plant and Apicomplexa Parasite Tubulin through Differential Screening Using In Silico and Assay-Based Approaches

article

Sulphamoylated 2-methoxyestradiol analogues induce apoptosis in adenocarcinoma cell lines.

scientific article

Suppression of nuclear oscillations in Saccharomyces cerevisiae expressing Glu tubulin.

scholarly article

Targeting LIM kinases in taxane resistant tumors

scientific article published on 24 July 2016

The pyrrolopyrimidine colchicine-binding site agent PP-13 reduces the metastatic dissemination of invasive cancer cells in vitro and in vivo

scientific article published on 07 December 2018

The third tubulin pool.

scientific article

Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends.

scientific article

Two Antagonistic Microtubule Targeting Drugs Act Synergistically to Kill Cancer Cells

scientific article published on 06 August 2020

Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation.

scientific article

[Chemical biology: cross-border strategies]

scientific article published on 24 December 2014

[On the road to deciphering the tubulin code: focus on acetylation and detyrosination]

scientific article published on 01 December 2018

β3 integrin-mediated spreading induced by matrix-bound BMP-2 controls Smad signaling in a stiffness-independent manner

scientific article published on 7 March 2016

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