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List of works by Daniel Christ

A Subset of Interleukin-21+ Chemokine Receptor CCR9+ T Helper Cells Target Accessory Organs of the Digestive System in Autoimmunity

scientific article published on 01 April 2011

Aggregation, stability, and formulation of human antibody therapeutics

scientific article published on January 2011

Bispecific antibodies with native chain structure.

scientific article

CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan

scientific article published on 12 August 2019

Cancer-associated noncoding mutations affect RNA G-quadruplex-mediated regulation of gene expression

scientific article

Challenges and opportunities for non-antibody scaffold drugs

scientific article

Circumventing the stability-function trade-off in an engineered FN3 domain

scientific article published on 29 August 2016

Clonal redemption and clonal anergy as mechanisms to balance B cell tolerance and immunity

scientific article published on 26 September 2019

Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization.

scientific article published on 13 June 2016

Cofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasis

scientific article

Crystal structure of duck egg lysozyme isoform II (DEL-II)

scientific article published on 22 August 2018

Cytosolic Recognition of RNA Drives the Immune Response to Heterologous Erythrocytes.

scientific article published in November 2017

DNA G-Quadruplex and i-Motif Structure Formation Is Interdependent in Human Cells

scientific article published on 30 November 2020

Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity

scientific article published on 18 September 2019

Differentiation of germinal center B cells into plasma cells is initiated by high-affinity antigen and completed by Tfh cells

scientific article published on 31 March 2017

Efficient Intracellular Delivery of CRISPR-Cas Ribonucleoproteins through Receptor Mediated Endocytosis

scientific article published on 21 February 2019

Engineering Escherichia coli heat-resistance by synthetic gene amplification

scientific article

Erratum: The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells

article

Expression of Human VH Single Domains as Fc Fusions in Mammalian Cells

scientific article published on 01 January 2019

Expression of IgG Monoclonals with Engineered Immune Effector Functions

scientific article published on 01 January 2018

Expression of high-affinity human antibody fragments in bacteria.

scientific article

Expression, purification and characterization of recombinant interleukin-21.

scientific article published on 25 August 2010

FAS Inactivation Releases Unconventional Germinal Center B Cells that Escape Antigen Control and Drive IgE and Autoantibody Production

scientific article published on 12 May 2015

Fully Human VH Single Domains That Rival the Stability and Cleft Recognition of Camelid Antibodies

scientific article

GDF15 mediates adiposity resistance through actions on GFRAL neurons in the hindbrain AP/NTS

scientific article published on 31 May 2019

General strategy for the generation of human antibody variable domains with increased aggregation resistance

scientific article

Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination.

scientific article published in April 2018

Hedgehog overexpression is associated with stromal interactions and predicts for poor outcome in breast cancer.

scientific article

Human Antibody Bispecifics through Phage Display Selection

scientific article published on 22 March 2019

I-motif DNA structures are formed in the nuclei of human cells.

scientific article published on 23 April 2018

IL-2 Shapes the Survival and Plasticity of IL-17-Producing γδ T Cells.

scientific article

IL-21 restricts virus-driven Treg cell expansion in chronic LCMV infection.

scientific article

Identification of aggregation inhibitors of the human antibody light chain repertoire by phage display

scientific article

Identification of functional similarities between proteins using directed evolution

scientific article published on 22 October 2003

Identification of protein domains by shotgun proteolysis

scientific article

Interleukin-21 is critically required in autoimmune and allogeneic responses to islet tissue in murine models.

scientific article

NSG-Pro mouse model for uncovering resistance mechanisms and unique vulnerabilities in human luminal breast cancers

scientific article published on 15 September 2021

Next-Generation Sequencing of Antibody Display Repertoires.

scientific article published on 2 February 2018

Potent antitumour activity of interleukin-2-Fc fusion proteins requires Fc-mediated depletion of regulatory T-cells

scientific article

Rapid prediction of expression and refolding yields using phage display.

scientific article

Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity.

scientific article

Repertoires of aggregation-resistant human antibody domains

scientific article

Selection of Antibody Fragments Against Structured DNA by Phage Display

scientific article published on 01 January 2018

Selection of human antibody fragments by phage display

scientific article

Sequence determinants of protein aggregation in human VH domains

scientific article

Sequencing and Affinity Determination of Antigen-Specific B Lymphocytes from Peripheral Blood

scientific article published on 01 January 2018

Solution structure of a soluble fragment derived from a membrane protein by shotgun proteolysis

scientific article

Stability engineering of the human antibody repertoire

scientific article

Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate

scientific article published on 12 May 2015

Structural basis of antigen recognition: crystal structure of duck egg lysozyme

scientific article published on 25 October 2017

Structural reconstruction of protein ancestry

scientific article

Structure and Characterisation of a Key Epitope in the Conserved C-Terminal Domain of the Malaria Vaccine Candidate MSP2.

scientific article published on 8 February 2017

Subcellular relocalization and nuclear redistribution of the RNA methyltransferases TRMT1 and TRMT1L upon neuronal activation

scientific article published on 15 February 2021

Subcellular relocalization and nuclear redistribution of the RNA methyltransferases TRMT1 and TRMT1L upon neuronal activation

Systematic functional identification of cancer multi-drug resistance genes

scientific article published on 07 February 2020

Tapping diversity lost in transformations--in vitro amplification of ligation reactions

scientific article (publication date: 2006)

The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells

scientific journal article

Thermodynamically stable aggregation-resistant antibody domains through directed evolution

scientific article published on 4 November 2007

Transient expression of human antibodies in mammalian cells.

scientific article