Search filters

List of works by Rachel E Rigby

Accurate and reliable high-throughput detection of copy number variation in the human genome

scientific article

Deoxyguanosine is a TLR7 agonist

scientific article published on 14 November 2019

Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development.

scientific article

Infection with a Brazilian isolate of Zika virus generates RIG-I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signalling

scientific article published on 23 March 2018

Mammalian mitochondrial DNA replication intermediates are essentially duplex but contain extensive tracts of RNA/DNA hybrid

scientific article

Multi-Modal Characterization of Monocytes in Idiopathic Pulmonary Fibrosis Reveals a Primed Type I Interferon Immune Phenotype

scientific article published on 05 March 2021

Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling

article published in the Proceedings of the National Academy of Sciences of the United States of America

Nucleic acid-mediated inflammatory diseases

scientific article published on September 2008

PA-X antagonises MAVS-dependent accumulation of early type I interferon messenger RNAs during influenza A virus infection

scientific article published on 10 May 2019

RNA degradation in antiviral immunity and autoimmunity

scientific article

RNA:DNA hybrids are a novel molecular pattern sensed by TLR9.

scientific article published on 10 February 2014

Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response

scientific article published on 22 February 2016

SAMHD1-dependent retroviral control and escape in mice.

scientific article published on 19 July 2013

SAMHD1-dependent retroviral control and escape in mice.

scientific article