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List of works by Erkki Ruoslahti

(64)Cu-labeled LyP-1-dendrimer for PET-CT imaging of atherosclerotic plaque

scientific article

A fragment of the HMGN2 protein homes to the nuclei of tumor cells and tumor endothelial cells in vivo

scientific article

A free cysteine prolongs the half-life of a homing peptide and improves its tumor-penetrating activity

scientific article published on 15 December 2013

A high-throughput label-free nanoparticle analyser ⬇️

scientific article published on March 6, 2011

A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors

scientific article

A novel vascular homing peptide strategy to selectively enhance pulmonary drug efficacy in pulmonary arterial hypertension

scientific article published on 6 January 2014

A surface-charge study on cellular-uptake behavior of F3-peptide-conjugated iron oxide nanoparticles

scientific article

A tumor-homing peptide with a targeting specificity related to lymphatic vessels

scientific article

A tumor-penetrating peptide enhances circulation-independent targeting of peritoneal carcinomatosis

scientific article published on 11 June 2015

Access granted: iRGD helps silicasome-encased drugs breach the tumor barrier.

scientific article published on 17 April 2017

Activated Src Oncogene Phosphorylates R-Ras and Suppresses Integrin Activity ⬇️

scientific article published on October 26, 2001

An endocytosis pathway initiated through neuropilin-1 and regulated by nutrient availability

scientific article

Anastellin, an FN3 fragment with fibronectin polymerization activity, resembles amyloid fibril precursors

scientific article

Angiostatic peptides use plasma fibronectin to home to angiogenic vasculature

scientific article

Anoikis effector Bit1 negatively regulates Erk activity

scholarly article

Antiangiogenic proteins require plasma fibronectin or vitronectin for in vivo activity

scientific article

Antiangiogenics meet nanotechnology

scientific article published in August 2002

Antitumor activity of a homing peptide that targets tumor lymphatics and tumor cells

scientific article

Application of a Proapoptotic Peptide to Intratumorally Spreading Cancer Therapy ⬇️

scientific article published on December 17, 2012

Binding of a C-end rule peptide to the neuropilin-1 receptor: a molecular modeling approach

scientific article

Biodegradable luminescent porous silicon nanoparticles for in vivo applications

scientific article

Biomimetic amplification of nanoparticle homing to tumors

scientific article

Bit1 in anoikis resistance and tumor metastasis ⬇️

scientific article published on January 31, 2013

C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration

scientific article

Cell spreading controls endoplasmic and nuclear calcium: a physical gene regulation pathway from the cell surface to the nucleus

scholarly article

Cell surface nucleolin antagonist causes endothelial cell apoptosis and normalization of tumor vasculature

scientific article

Clot-targeted micellar formulation improves anticoagulation efficacy of bivalirudin

scientific article

Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs

scientific article

Composite Porous Silicon-Silver Nanoparticles as Theranostic Antibacterial Agents

scientific article

Contact activation of kallikrein-kinin system by superparamagnetic iron oxide nanoparticles in vitro and in vivo

scientific article published on 07 June 2009

Cooperative nanomaterial system to sensitize, target, and treat tumors

scientific article

Cooperative nanoparticles for tumor detection and photothermally triggered drug delivery

scientific article

Correction for Fogal et al., "Mitochondrial p32 Protein Is a Critical Regulator of Tumor Metabolism via Maintenance of Oxidative Phosphorylation".

scientific article published on 29 June 2017

Crystal structure of a human peptidyl-tRNA hydrolase reveals a new fold and suggests basis for a bifunctional activity

scientific article

De novo design of a tumor-penetrating peptide

scientific article published on 14 November 2012

Different Effect of Hydrogelation on Antifouling and Circulation Properties of Dextran–Iron Oxide Nanoparticles ⬇️

scientific article published on February 2, 2012

Differential proteomics analysis of the surface heterogeneity of dextran iron oxide nanoparticles and the implications for their in vivo clearance

scientific article published on 26 April 2009

Drug identification through in vivo screening of chemical libraries

scientific article published in June 2004

Drug targeting to specific vascular sites

scientific article

Dynamic imaging of arginine-rich heart-targeted vehicles in a mouse model

scientific article

Effect of the lipid chain melting transition on the stability of DSPE-PEG(2000) micelles

scientific article published on July 2009

Engineering strategy to improve peptide analogs: from structure-based computational design to tumor homing

scientific article published on 14 December 2012

Enhanced baculovirus-mediated transduction of human cancer cells by tumor-homing peptides

scientific article published in July 2006

Enhanced magnetic resonance contrast of Fe₃O₄ nanoparticles trapped in a porous silicon nanoparticle host

scientific article published on 15 August 2011

Etchable plasmonic nanoparticle probes to image and quantify cellular internalization

scientific article

Gated Luminescence Imaging of Silicon Nanoparticles

scientific article published on 9 June 2015

Identification of a peptide recognizing cerebrovascular changes in mouse models of Alzheimer's disease

scientific article published on 10 November 2017

In silico molecular engineering for a targeted replacement in a tumor-homing peptide

scientific article published on June 2009

In vivo cation exchange in quantum dots for tumor-specific imaging

scientific article published on 24 August 2017

In vivo selection of tumor-specific antibodies

scientific article published on October 2013

In vivo tumor cell targeting with "click" nanoparticles

scientific article

Increasing Tumor Accessibility with Conjugatable Disulfide-Bridged Tumor-Penetrating Peptides for Cancer Diagnosis and Treatment.

scientific article

Integrin signaling and matrix assembly

scientific article

Ligand-modified vesicular stomatitis virus glycoprotein displays a temperature-sensitive intracellular trafficking and virus assembly phenotype

scientific article published on January 2004

Lymphangiogenesis and Cancer: Fig. 1

Lymphatic zip codes in premalignant lesions and tumors

scientific article published in June 2006

Magnetic Iron Oxide Nanoworms for Tumor Targeting and Imaging

scientific article

Magnetic luminescent porous silicon microparticles for localized delivery of molecular drug payloads

scientific article

Mapping of Vascular ZIP Codes by Phage Display ⬇️

scientific article published on January 1, 2012

Mechanisms and Barriers in Cancer Nanomedicine: Addressing Challenges, Looking for Solutions

scientific article

Metadherin, a cell surface protein in breast tumors that mediates lung metastasis

scientific article

Metastasis of tumor cells is enhanced by downregulation of Bit1.

scientific article

Micellar hybrid nanoparticles for simultaneous magnetofluorescent imaging and drug delivery

scientific article published on January 2008

Mitochondrial p32 protein is a critical regulator of tumor metabolism via maintenance of oxidative phosphorylation

scientific article

Mitochondrial/cell-surface protein p32/gC1qR as a molecular target in tumor cells and tumor stroma

scientific article

Molecular changes in the vasculature of injured tissues

scientific article

Molecular profiling of heart endothelial cells

scientific article

Molecular specialization of breast vasculature: a breast-homing phage-displayed peptide binds to aminopeptidase P in breast vasculature

scientific article

Nanocrystal targeting in vivo

scientific article

Nanoparticle amplification via photothermal unveiling of cryptic collagen binding sites

scientific article published on 14 June 2013

Nanoparticle-induced vascular blockade in human prostate cancer

scientific article

Nanoparticles coated with the tumor-penetrating peptide iRGD reduce experimental breast cancer metastasis in the brain

scientific article published on 14 April 2015

Nanoparticles that communicate in vivo to amplify tumour targeting ⬇️

scientific article published on June 19, 2011

Neuropilin-1 and heparan sulfate proteoglycans cooperate in cellular uptake of nanoparticles functionalized by cationic cell-penetrating peptides

scientific article

New Insights into "Permeability" as in the Enhanced Permeability and Retention Effect of Cancer Nanotherapeutics

scientific article

New p32/gC1qR Ligands for Targeted Tumor Drug Delivery

scientific article

New way to activate caspases

scientific article published in Nature

Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels

scientific article

Paclitaxel-Loaded Polymersomes for Enhanced Intraperitoneal Chemotherapy

scientific article published on 15 February 2016

Peptide targeting of tumor lymph vessels

scientific article published on January 2008

Peptide-directed highly selective targeting of pulmonary arterial hypertension

scientific article

Peptides as Targeting Elements and Tissue Penetration Devices for Nanoparticles ⬇️

scientific article published on 02 May 2012

Peptides selected for binding to clotted plasma accumulate in tumor stroma and wounds

scientific article

Peptides targeting inflamed synovial vasculature attenuate autoimmune arthritis ⬇️

scientific article published on July 18, 2011

Plaque-penetrating peptide inhibits development of hypoxic atherosclerotic plaque

scientific article published on 13 July 2016

Plasma fibronectin promotes lung metastasis by contributions to fibrin clots and tumor cell invasion

scientific article

Porous Silicon Nanoparticle Delivery of Tandem Peptide Anti-Infectives for the Treatment of Pseudomonas aeruginosa Lung Infections

scientific article published on 12 July 2017

Proapoptotic peptide-mediated cancer therapy targeted to cell surface p32.

scientific article published on 20 August 2013

Progressive vascular changes in a transgenic mouse model of squamous cell carcinoma

scientific article published in November 2003

Proteasome activator complex PA28 identified as an accessible target in prostate cancer by in vivo selection of human antibodies

scientific article

Protein kinase D is a positive regulator of Bit1 apoptotic function

scientific article

Proteolytic actuation of nanoparticle self-assembly

scientific article published on May 2006

Quantity and accessibility for specific targeting of receptors in tumours

scientific article

R-Ras is a global regulator of vascular regeneration that suppresses intimal hyperplasia and tumor angiogenesis

scientific article

Ratiometric in vivo auditioning of targeted silver nanoparticles

scientific article published on 11 July 2017

Recognition of dextran-superparamagnetic iron oxide nanoparticle conjugates (Feridex) via macrophage scavenger receptor charged domains

scientific article published on 26 April 2012

Reprogramming human retinal pigmented epithelial cells to neurons using recombinant proteins

scientific article published on 8 October 2014

Selection of phage-displayed peptides on live adherent cells in microfluidic channels

scientific article

Selection strategies for anticancer antibody discovery: searching off the beaten path

scientific article published on 26 March 2015

Selective Targeting of a Novel Vasodilator to the Uterine Vasculature to Treat Impaired Uteroplacental Perfusion in Pregnancy

scientific article published on 29 August 2017

Self-Sealing Porous Silicon-Calcium Silicate Core-Shell Nanoparticles for Targeted siRNA Delivery to the Injured Brain.

scientific article published on 6 July 2016

Site-specific targeting of antibody activity in vivo mediated by disease-associated proteases

scientific article published on 23 May 2012

Small GTPase R-Ras Regulates Integrity and Functionality of Tumor Blood Vessels ⬇️

scientific article published on August 14, 2012

Specialization of tumour vasculature

scientific article

Specific penetration and accumulation of a homing peptide within atherosclerotic plaques of apolipoprotein E-deficient mice

scientific article

Stage-specific vascular markers revealed by phage display in a mouse model of pancreatic islet tumorigenesis

scientific article published in November 2003

Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1

scientific article published in Nature

Supramolecular nanoparticles that target phosphoinositide-3-kinase overcome insulin resistance and exert pronounced antitumor efficacy

scientific article published on 11 October 2013

Synthesis of linear and cyclic peptide-PEG-lipids for stabilization and targeting of cationic liposome-DNA complexes

scientific article published on 4 February 2016

Synthetic surfaces for human embryonic stem cell culture

scientific article published on 2 February 2010

Systematic surface engineering of magnetic nanoworms for in vivo tumor targeting

scientific article

TLE1 is an anoikis regulator and is downregulated by Bit1 in breast cancer cells

scientific article

Target-seeking antifibrotic compound enhances wound healing and suppresses scar formation in mice ⬇️

scientific article published on November 24, 2010

Targeted Antiscarring Therapy for Tissue Injuries

scientific article published in March 2013

Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma

scientific article

Targeted quantum dot conjugates for siRNA delivery

scientific article published on 14 July 2007

Targeted silver nanoparticles for ratiometric cell phenotyping

scientific article published on 8 December 2015

Targeted tumor-penetrating siRNA nanocomplexes for credentialing the ovarian cancer oncogene ID4

scientific article published on August 2012

Targeting atherosclerosis by using modular, multifunctional micelles

scholarly article

Targeting bladder tumor cells in vivo and in the urine with a peptide identified by phage display

scientific article published in January 2007

Targeting of albumin-embedded paclitaxel nanoparticles to tumors

scientific article

Targeting of drugs and nanoparticles to tumors

scientific article

Targeting the prostate for destruction through a vascular address

scientific article

The RGD story: a personal account

scientific article

The anti-angiogenic peptide anginex disrupts the cell membrane

scientific article

The multicompartmental p32/gClqR as a new target for antibody-based tumor targeting strategies

scientific article

The multicompartmental p32/gClqR as a new target for antibody-based tumor targeting strategies.

scientific article published in June 2011

Tissue-penetrating delivery of compounds and nanoparticles into tumors

scientific article

Trophoblast cell activation by trophinin ligation is implicated in human embryo implantation

scientific article published on 26 February 2007

Tumor penetrating peptides for improved drug delivery

scientific article

Tumor-Penetrating Nanosystem Strongly Suppresses Breast Tumor Growth.

scientific article published on 8 February 2017

Tumor-Targeted Multimodal Optical Imaging with Versatile Cadmium-Free Quantum Dots

scientific article published on 02 December 2015

Tumor-homing peptides as tools for targeted delivery of payloads to the placenta.

scientific article published on 06 May 2016

Tumor-penetrating iRGD peptide inhibits metastasis

scientific article

Tumor-penetrating peptides

scientific article

Urokinase-controlled tumor penetrating peptide

scientific article published on 19 April 2016

Using shape effects to target antibody-coated nanoparticles to lung and brain endothelium

scientific article published on 10 June 2013

Vascular Histomolecular Analysis by Sequential Endoarterial Biopsy in a Shunt Model of Pulmonary Hypertension ⬇️

scientific article published on January 1, 2013

Vascular changes in tumors resistant to a vascular disrupting nanoparticle treatment.

scientific article published on 10 October 2017

X-ray computed tomography imaging of breast cancer by using targeted peptide-labeled bismuth sulfide nanoparticles

scientific article

alpha5beta1 integrin stimulates Bcl-2 expression and cell survival through Akt, focal adhesion kinase, and Ca2+/calmodulin-dependent protein kinase IV.

scientific article

iRGD peptide conjugation potentiates intraperitoneal tumor delivery of paclitaxel with polymersomes

scientific article published on 20 July 2016

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