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List of works by Yoshihiro Tokudome

A new strategy for the passive skin delivery of nanoparticulate, high molecular weight hyaluronic acid prepared by a polyion complex method

scientific article

Antitumor activity of vincristine encapsulated in glucuronide-modified long-circulating liposomes in mice bearing Meth A sarcoma

scientific article published on 01 February 1996

Chimyl Alcohol Suppresses PGE2 Synthesis by Human Epidermal Keratinocytes through the Activation of PPAR-γ.

scientific article published on 9 March 2018

Effect of Zinc-Containing .BETA.-Tricalcium Phosphate Nano Particles Injection on Jawbone Mineral Density and Mechanical Strength of Osteoporosis Model Rats ⬇️

scientific article published on January 1, 2011

Effect of hyaluronan tetrasaccharides on epidermal differentiation in normal human epidermal keratinocytes.

scientific article published on 2 December 2013

Effect of liquid crystals with cyclodextrin on the bioavailability of a poorly water-soluble compound, diosgenin, after its oral administration to rats

scientific article published on 19 June 2014

Effect of serum protein binding on real-time trafficking of liposomes with different charges analyzed by positron emission tomography

scientific article published on 01 April 1996

Effect of topically applied sphingomyelin-based liposomes on the ceramide level in a three-dimensional cultured human skin model

scientific article published on 01 March 2010

Effect of β-cyclodextrin derivatives on the diosgenin absorption in Caco-2 cell monolayer and rats

scientific article published on 01 January 2014

Effects of low molecular weight soybean peptide on mRNA and protein expression levels of differentiation markers in normal human epidermal keratinocytes

scientific article published on 15 May 2014

Effects of solid-state reaction between paracetamol and cloperastine hydrochloride on the pharmaceutical properties of their preparations

scientific article published on 29 October 2006

Effects of soybean peptide and collagen peptide on collagen synthesis in normal human dermal fibroblasts.

scientific article published on 20 January 2012

Efficacy of the injectable calcium phosphate ceramics suspensions containing magnesium, zinc and fluoride on the bone mineral deficiency in ovariectomized rats

scientific article published on 01 January 2008

Enhancement of Diosgenin Distribution in the Skin by Cyclodextrin Complexation Following Oral Administration ⬇️

scientific article published on January 1, 2013

Epidermal permeability barrier function and sphingolipid content in the skin of sphingomyelin synthase 2 deficient mice

scientific article

Esterase Activity and Intracellular Localization in Reconstructed Human Epidermal Cultured Skin Models

scientific article published on 29 May 2015

Evaluation of drug targeting strategies and liposomal trafficking.

scientific article

Glyceraldehyde-Derived Advanced Glycation End Products Accumulate Faster Than Nε-(Carboxymethyl) Lysine.

scientific article published on 21 June 2017

Hyaluronan tetrasaccharides stimulate ceramide production through upregulated mRNA expression of ceramide synthesis-associated enzymes.

scientific article published on 28 December 2015

Increase in ceramide level after application of various sizes of sphingomyelin liposomes to a cultured human skin model

scientific article published on 26 March 2011

Induction of coenzyme A-dependent transacylation activity in rat liver microsomes by administration of clofibrate

scientific article published on 01 March 1994

Liposomal Arg-Gly-Asp analogs effectively inhibit metastatic B16 melanoma colonization in murine lungs

scientific article published on 01 January 1996

Long-term therapeutic effect of novel calcium phosphate-based compounds injected in ovariectomized rats.

scientific article

Mechanism of the synergic effects of calcium chloride and electroporation on the in vitro enhanced skin permeation of drugs.

scientific article published in March 2004

Non-invasive and rapid analysis for observation of internal structure of press-coated tablet using X-ray computed tomography.

scientific article

Permeation Pathway of Macromolecules and Nanospheres through Skin ⬇️

scientific article published on January 1, 2010

Permeation of Hydrophilic Molecules across Glycated Skin Is Differentially Regulated by the Stratum Corneum and Epidermis-Dermis

scientific article published in January 2015

Permeation of hyaluronan tetrasaccharides through hairless mouse skin: an in vitro and in vivo study

scientific article published on 28 June 2012

Possibility and effectiveness of drug delivery to skin by needle-free injector.

scientific article published on 17 February 2010

Possibility of Alveolar Bone Promoting Enhancement by Using Lipophilic and/or Hydrophilic Zinc Related Compounds in Zinc-Deficient Osteoporosis Rats ⬇️

scientific article published on January 1, 2012

Preparation and characterization of ceramide-based liposomes with high fusion activity and high membrane fluidity.

scientific article

Real-time analysis of liposomal trafficking in tumor-bearing mice by use of positron emission tomography

scientific article published on 01 August 1995

Recovery Effects of Oral Administration of Glucosylceramide and Beet Extract on Skin Barrier Destruction by UVB in Hairless Mice.

scientific article published on 27 October 2017

The Effect of Glycation on Epidermal Lipid Content, Its Metabolism and Change in Barrier Function

scientific article published on 23 August 2016

The effects of calcium chloride and sodium chloride on the electroporation-mediated skin permeation of fluorescein isothiocyanate (FITC)-dextrans in vitro.

scientific article published in October 2003

The synergic effects of various electrolytes and electroporation on the in vitro skin permeation of calcein.

scientific article published in September 2003

Upregulation of gene expression levels of ceramide metabolic enzymes after application of sphingomyelin-based liposomes to a three-dimensional cultured human epidermis model.

scientific article published on 16 March 2016

[Improvement of the Skin Barrier Function with Physiologically Active Substances]

scientific article published on 01 January 2019

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