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List of works by Giovanna Cutrona

A non-invasive approach to monitor chronic lymphocytic leukemia engraftment in a xenograft mouse model using ultra-small superparamagnetic iron oxide-magnetic resonance imaging (USPIO-MRI).

scientific article published on 15 July 2016

A progression-risk score to predict treatment-free survival for early stage chronic lymphocytic leukemia patients.

scientific article published on 9 December 2015

A retinoic acid resistant HL-60 cell clone sensitive to N-(4-hydroxyphenyl) retinamide-mediated clonal growth inhibition

scientific article published on 01 March 1995

A reversible carnitine palmitoyltransferase (CPT1) inhibitor offsets the proliferation of chronic lymphocytic leukemia cells

scientific article published on 21 June 2018

A seven-gene expression panel distinguishing clonal expansions of pre-leukemic and chronic lymphocytic leukemia B cells from normal B lymphocytes.

scientific article published on 30 August 2015

An in-depth evaluation of acalabrutinib for the treatment of mantle-cell lymphoma

scientific article published on 18 November 2019

Association between gene and miRNA expression profiles and stereotyped subset #4 B-cell receptor in chronic lymphocytic leukemia

scientific article published on 10 April 2015

B cell chronic lymphocytic leukaemia/small lymphocytic lymphoma: role of ZAP70 determination on bone marrow biopsy specimens

scientific article

B lymphocytes in humans express ZAP-70 when activated in vivo.

scientific article published in March 2006

Baff serum level predicts time to first treatment in early chronic lymphocytic leukemia

scientific article

Biological and clinical relevance of quantitative global methylation of repetitive DNA sequences in chronic lymphocytic leukemia

scientific article published on February 2011

CD38 and chronic lymphocytic leukemia: a decade later ⬇️

scientific article published on July 15, 2011

CD5+ B cells with the features of subepithelial B cells found in human tonsils

scientific article published on 01 August 2007

Cellular and Molecular Characterization of Two Cases of Castleman's Disease, Plasma Cell Variant

scientific article published on 01 January 1991

Chromosome 2p gain in monoclonal B-cell lymphocytosis and in early stage chronic lymphocytic leukemia.

scientific article published on 9 October 2012

Chronic lymphocytic leukemia nurse-like cells express hepatocyte growth factor receptor (c-MET) and indoleamine 2,3-dioxygenase and display features of immunosuppressive type 2 skewed macrophages

scientific article

Clinical categories identified by a new prognostic index reflect biological characteristics of patients in early chronic lymphocytic leukemia: The Gruppo Italiano Studio Linfomi (GISL) experience

scientific article published on 31 March 2010

Clinical monoclonal B lymphocytosis versus Rai 0 chronic lymphocytic leukemia: A comparison of cellular, cytogenetic, molecular, and clinical features.

scientific article

Clonal heterogeneity in chronic lymphocytic leukemia cells: superior response to surface IgM cross-linking in CD38, ZAP-70-positive cells

scientific article

Comparison between the CLL-IPI and the Barcelona-Brno prognostic model: Analysis of 1299 newly diagnosed cases.

scientific article published on 3 November 2017

Comparison of ibrutinib and idelalisib plus rituximab in real-life relapsed/resistant chronic lymphocytic leukemia cases

scientific article published on 30 December 2020

Constitutive expression of IL-12R beta 2 on human multiple myeloma cells delineates a novel therapeutic target.

scientific article published on 12 May 2008

Corrigendum to “Lack of mutagenicity and clastogenicity of PNAEμ-NLS targeted to a regulatory sequence of the translocated c-myc oncogene in Burkitt's lymphoma” [Mutat. Res. 628 (2007) 129–137]

scholarly article published in Mutation Research

Definition of progression risk based on combinations of cellular and molecular markers in patients with Binet stage A chronic lymphocytic leukaemia

scientific article published on 6 May 2009

Distinct patterns of global promoter methylation in early stage chronic lymphocytic leukemia

scientific article published on 18 December 2013

Effects in live cells of a c-myc anti-gene PNA linked to a nuclear localization signal

scientific article published on 01 March 2000

Effects of miRNA-15 and miRNA-16 expression replacement in chronic lymphocytic leukemia: implication for therapy

scientific article published on 5 January 2017

Epigenetic mechanisms regulate ΔNP73 promoter function in human tonsil B cells ⬇️

scientific article published on December 3, 2010

Expanding the repertoire of miRNAs and miRNA-offset RNAs expressed in multiple myeloma by small RNA deep sequencing

scientific article published on 19 February 2019

Expression of CD10 by human T cells that undergo apoptosis both in vitro and in vivo

scientific article published on 01 April 2001

Expression of immunoglobulin receptors with distinctive features indicating antigen selection by marginal zone B cells from human spleen.

scientific article published on 17 September 2013

External validation on a prospective basis of a nomogram for predicting the time to first treatment in patients with chronic lymphocytic leukemia

scientific article published on 7 December 2012

Frequency and clinical relevance of coding and noncoding NOTCH1 mutations in early stage Binet A chronic lymphocytic leukemia patients

scientific article published on 25 February 2020

Functional Activation of Osteoclast Commitment in Chronic Lymphocytic Leukaemia: a Possible Role for RANK/RANKL Pathway.

scientific article published on 26 October 2017

H and L ferritin gene expression in U937 cells induced to macrophage differentiation.

scientific article published on December 1993

Hepatocyte Growth Factor: A Microenvironmental Resource for Leukemic Cell Growth ⬇️

scientific article published on 12 January 2019

Heterogeneity of TP53 Mutations and P53 Protein Residual Function in Cancer: Does It Matter?

scientific article published on 28 October 2020

Heterogeneous expression and function of IL-21R and susceptibility to IL-21-mediated apoptosis in follicular lymphoma cells

scientific article

Heterogeneous expression of the collagen receptor DDR1 in chronic lymphocytic leukaemia and correlation with progression.

scientific article published on 06 January 2017

Heterogeneousp53 mutations in a Burkitt lymphoma from an AIDS patient with monoclonalc-myc andVDJ rearrangements ⬇️

scientific article published on December 10, 1997

High-throughput sequencing for the identification of NOTCH1 mutations in early stage chronic lymphocytic leukaemia: biological and clinical implications

scientific article

Identification of HSP-60 as the specific antigen of IgM produced by BRG-lymphoma cells

scientific article published on 01 April 1999

Igs expressed by chronic lymphocytic leukemia B cells show limited binding-site structure variability.

scientific article published in May 2013

Immunoglobulin heavy chain variable region gene and prediction of time to first treatment in patients with chronic lymphocytic leukemia: Mutational load or mutational status? Analysis of 1003 cases

scientific article published on 30 July 2018

Increased serum BAFF (B-cell activating factor of the TNF family) level is a peculiar feature associated with familial chronic lymphocytic leukemia

scientific article

Inhibition of Burkitt's lymphoma cells growth in SCID mice by a PNA specific for a regulatory sequence of the translocated c-myc

scientific article published on 20 October 2006

Insulin growth factor 1 receptor expression is associated with NOTCH1 mutation, trisomy 12 and aggressive clinical course in chronic lymphocytic leukaemia

scientific article

Integrative genomics analyses reveal molecularly distinct subgroups of B-cell chronic lymphocytic leukemia patients with 13q14 deletion.

scientific article published on 14 October 2010

Interleukin 21 Controls mRNA and MicroRNA Expression in CD40-Activated Chronic Lymphocytic Leukemia Cells

scientific article published on 25 August 2015

Interleukin-21 receptor (IL-21R) is up-regulated by CD40 triggering and mediates proapoptotic signals in chronic lymphocytic leukemia B cells

scientific article

Intraclonal cell expansion and selection driven by B cell receptor in chronic lymphocytic leukemia

scientific article

Is ZAP70 still a key prognostic factor in early stage chronic lymphocytic leukaemia? Results of the analysis from a prospective multicentre observational study.

scientific article published on 11 September 2014

Lack of mutagenicity and clastogenicity of PNAEmu-NLS targeted to a regulatory sequence of the translocated c-myc oncogene in Burkitt's lymphoma.

scientific article published on 8 January 2007

Markers of increased angiogenesis and their correlation with biological parameters identifying high-risk patients in early B-cell chronic lymphocytic leukemia

scientific article published on 07 May 2007

Microenvironmental regulation of the IL-23R/IL-23 axis overrides chronic lymphocytic leukemia indolence.

scientific article published in February 2018

Molecular and transcriptional characterization of 17p loss in B-cell chronic lymphocytic leukemia

scientific article published on 01 September 2008

More on the determination of Ki-67 as a novel potential prognostic marker in B-cell chronic lymphocytic leukemia

scientific article published in December 2010

Multiplex ligation-dependent probe amplification and fluorescence in situ hybridization to detect chromosomal abnormalities in Chronic lymphocytic leukemia: A comparative study

scientific article published on 02 June 2011

Mutation pattern of paired immunoglobulin heavy and light variable domains in chronic lymphocytic leukemia B cells

scientific article (publication date: 2011)

NEAT1 Long Isoform Is Highly Expressed in Chronic Lymphocytic Leukemia Irrespectively of Cytogenetic Groups or Clinical Outcome

scientific article published on 13 March 2020

PNAEmu can significantly reduce Burkitt's lymphoma tumor burden in a SCID mice model: cells dissemination similar to the human disease.

scientific article published on 10 April 2009

Predictive value of the CLL-IPI in CLL patients receiving chemo-immunotherapy as first-line treatment

scientific article published on 24 July 2018

Production of inflammatory cytokines by Epstein-Barr virus (EBV)-infected lymphoblastoid cell lines spontaneously originated from the peripheral blood of patients with human immunodeficiency virus (HIV) infection.

scientific article published on November 1995

Prognostic relevance of serum levels and cellular expression of adiponectin in B-cell chronic lymphocytic leukemia

scientific article published on 27 September 2008

Prognostic relevance ofin vitroresponse to cell stimulation via surface IgD in binet stage a CLL

scientific article published on 08 December 2009

Prospective validation of a risk score based on biological markers for predicting progression free survival in Binet stage A chronic lymphocytic leukemia patients: Results of the multicenter O-CLL1-GISL study

scientific article published on 18 April 2014

Prospective validation of predictive value of abdominal computed tomography scan on time to first treatment in Rai 0 chronic lymphocytic leukemia patients: results of the multicenter O-CLL1-GISL study

scientific article published on 31 March 2015

Redefining the prognostic likelihood of chronic lymphocytic leukaemia patients with borderline percentage of immunoglobulin variable heavy chain region mutations

scientific article published on 16 February 2020

Relevance of stereotyped B-cell receptors in the context of the molecular, cytogenetic and clinical features of chronic lymphocytic leukemia

scientific article

Relevance of telomere/telomerase system impairment in early stage chronic lymphocytic leukemia

scientific article

Role of surface IgM and IgD on survival of the cells from B-cell chronic lymphocytic leukemia

scientific article (publication date: 15 March 2002)

Serum level of CD26 predicts time to first treatment in early B-chronic lymphocytic leukemia

scientific article

Serum thrombopoietin compared with ZAP-70 and immunoglobulin heavy-chain gene mutation status as a predictor of time to first treatment in early chronic lymphocytic leukemia

article

Small nucleolar RNAs as new biomarkers in chronic lymphocytic leukemia

scientific article

Surrogate molecular markers for IGHV mutational status in chronic lymphocytic leukemia for predicting time to first treatment

scientific article published on 19 May 2015

Survival and Immunosuppression Induced by Hepatocyte Growth Factor in Chronic Lymphocytic Leukemia.

scientific article

The chronic lymphocytic leukemia international prognostic index predicts time to first treatment in early CLL: Independent validation in a prospective cohort of early stage patients.

scientific article published on 27 July 2016

The cumulative amount of serum-free light chain is a strong prognosticator in chronic lymphocytic leukemia

scientific article published on 13 October 2011

The opposite effects of IL-15 and IL-21 on CLL B cells correlate with differential activation of the JAK/STAT and ERK1/2 pathways

scientific article

The peptide nucleic acid targeted to a regulatory sequence of the translocated c-myc oncogene in Burkitt's lymphoma lacks immunogenicity: follow-up characterization of PNAEmu-NLS

scientific article published on 01 January 2007

The propensity to apoptosis of centrocytes and centroblasts correlates with elevated levels of intracellular myc protein

scientific article published on 01 January 1997

The utility of two prognostic models for predicting time to first treatment in early chronic lymphocytic leukemia patients: results of a comparative analysis.

scientific article published on 15 March 2013

Therapeutically promising PNA complementary to a regulatory sequence for c-myc: pharmacokinetics in an animal model of human Burkitt's lymphoma.

scientific article published on January 2005

Time to first treatment and P53 dysfunction in chronic lymphocytic leukaemia: results of the O-CLL1 study in early stage patients

scientific article published on 28 October 2020

Toll-like receptor 9 stimulation can induce IκBζ expression and IgM secretion in chronic lymphocytic leukemia cells.

scientific article

Toll-like receptor stimulation in splenic marginal zone lymphoma can modulate cell signaling, activation and proliferation

scientific article published on 20 August 2015

Total body computed tomography scan in the initial work-up of Binet stage A chronic lymphocytic leukemia patients: Results of the prospective, multicenter O-CLL1-GISL study

scientific article published on 12 June 2013

Transfection of the c-myc oncogene into normal Epstein-Barr virus-harboring B cells results in new phenotypic and functional features resembling those of Burkitt lymphoma cells and normal centroblasts

scientific article

Transforming growth factor beta-1 (TGF-beta 1) released by an Epstein-Barr virus (EBV) positive spontaneous lymphoblastoid cell line from a patient with Kostmann's congenital neutropenia inhibits the growth of normal committed haemopoietic progenito

scientific article published on December 1993

Validation of a biological score to predict response in chronic lymphocytic leukemia patients treated front-line with bendamustine and rituximab

scientific article published on 20 March 2018

Validation of a survival-risk score (SRS) in relapsed/refractory CLL patients treated with idelalisib-rituximab

scientific article published on 16 September 2020

Validation of the CLL-IPI and comparison with the MDACC prognostic index in newly diagnosed patients.

scientific article published on 22 August 2016

c-myc proto-oncogene expression by germinal center B cells isolated from human tonsils

scientific article published on 01 April 1997

lncRNA profiling in early-stage chronic lymphocytic leukemia identifies transcriptional fingerprints with relevance in clinical outcome

scientific article published on 9 September 2016

microRNAome Expression in Chronic Lymphocytic Leukemia: Comparison with Normal B-cell Subsets and Correlations with Prognostic and Clinical Parameters

scientific article published on 10 June 2014

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