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List of works by Alastair Peter Greystoke

A Pilot Study Assessing the Prognostic Value of CK18 and nDNA Biomarkers in Severe Sepsis Patients

A phase I pharmacokinetic and pharmacodynamic study of the oral mitogen-activated protein kinase kinase (MEK) inhibitor, WX-554, in patients with advanced solid tumours

scientific article published on 28 September 2016

A phase I study of intravenous TZT-1027 administered on day 1 and day 8 of a three-weekly cycle in combination with carboplatin given on day 1 alone in patients with advanced solid tumours

scientific article published on 25 May 2006

A phase I study of the safety and tolerability of olaparib (AZD2281, KU0059436) and dacarbazine in patients with advanced solid tumours

scientific article

A phase I, dose escalation, pharmacodynamic, pharmacokinetic, and food-effect study of α2 integrin inhibitor E7820 in patients with advanced solid tumors

scientific article published on 2 April 2016

A phase I, dose-escalation study of the multitargeted receptor tyrosine kinase inhibitor, golvatinib, in patients with advanced solid tumors.

scientific article published on 2 October 2014

A study to investigate dose escalation of doxorubicin in ABVD chemotherapy for Hodgkin lymphoma incorporating biomarkers of response and toxicity

scientific article published on 17 October 2013

ASCEND-8: A Randomized Phase 1 Study of Ceritinib, 450 mg or 600 mg, Taken with a Low-Fat Meal versus 750 mg in Fasted State in Patients with Anaplastic Lymphoma Kinase (ALK)-Rearranged Metastatic Non-Small Cell Lung Cancer (NSCLC).

scientific article published on 17 July 2017

An introduction to stratified medicine

scientific article published on 04 August 2015

Assessment of diurnal changes and confounding factors that affect circulating cell death biomarker levels: a short communication.

scientific article published on 21 June 2013

Biomarker method validation in anticancer drug development

scientific article

Biomarkers of cell death applicable to early clinical trials

scientific article published on 27 March 2012

Cardiopulmonary fitness before and after neoadjuvant chemotherapy in patients with oesophagogastric cancer.

scientific article published on 30 March 2018

Clinical Significance and Molecular Characteristics of Circulating Tumor Cells and Circulating Tumor Microemboli in Patients With Small-Cell Lung Cancer

article

Cost-effectiveness of osimertinib in the UK for advanced EGFR-T790M non-small cell lung cancer.

scientific article published on 7 September 2017

Detection of PIK3CA mutations in circulating free DNA in patients with breast cancer

scientific article published on 28 January 2010

Development of a circulating miRNA assay to monitor tumor burden: From mouse to man

scientific article published on 28 October 2015

Evaluation and Prognostic Significance of Circulating Tumor Cells in Patients With Non–Small-Cell Lung Cancer

article

Evaluation of circulating tumor cells and serological cell death biomarkers in small cell lung cancer patients undergoing chemotherapy

scientific article published on 23 July 2009

First-in-Human Pharmacokinetic and Pharmacodynamic Study of the Dual m-TORC 1/2 Inhibitor AZD2014.

scientific article published on 24 March 2015

How many diseases are colorectal cancer?

scientific article

Isolation and Extraction of Circulating Tumor DNA from Patients with Small Cell Lung Cancer

scientific article published on 01 August 2008

Issues on fit-for-purpose validation of a panel of ELISAs for application as biomarkers in clinical trials of anti-Angiogenic drugs.

scientific article

Learning from toxicity patterns in phase I trials during the era of mechanism targeted agents.

scientific article published on 17 April 2012

Management of ceritinib therapy and adverse events in patients with ALK-rearranged non-small cell lung cancer.

scientific article published on 09 June 2017

Metastatic Brain Disease from Non-small Cell Lung Cancer - Getting Back to the Drawing Board.

scientific article

SELECT-3: a phase I study of selumetinib in combination with platinum-doublet chemotherapy for advanced NSCLC in the first-line setting

scientific article published on 24 August 2017

Serum biomarkers of apoptosis

Spindle cell carcinoma of the head and neck region: treatment and outcomes of 15 patients

scientific article

The Effect of Food or Omeprazole on the Pharmacokinetics of Osimertinib in Patients With Non-Small-Cell Lung Cancer and in Healthy Volunteers.

scientific article published on 26 November 2017

The interaction between prognostic and pharmacodynamic biomarkers.

scientific article published on 03 September 2013

The use of circulating biomarkers in early clinical trials in patients with cancer

scientific article published on 06 October 2015

Transfer and Metabolism of Prostaglandin E2in the Dual Perfused Human Placenta

scientific article published on 01 January 2000

Tumorigenicity and genetic profiling of circulating tumor cells in small-cell lung cancer.

scientific article published in June 2014

Update on tubulin-binding agents.

scientific article

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