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List of works by Emma Jane Dean

A Phase Ib, Dose-Finding Study of Erlotinib in Combination With a Fixed Dose of Pertuzumab in Patients With Advanced Non–Small-Cell Lung Cancer

scientific article published on 19 May 2012

A phase I dose-escalation and bioavailability study of oral and intravenous formulations of erlotinib (Tarceva, OSI-774) in patients with advanced solid tumors of epithelial origin

scientific article published on 3 December 2009

A phase I pharmacokinetic and pharmacodynamic study of the oral mitogen-activated protein kinase kinase (MEK) inhibitor, WX-554, in patients with advanced solid tumours

scientific article published on 28 September 2016

A phase I, dose escalation, pharmacodynamic, pharmacokinetic, and food-effect study of α2 integrin inhibitor E7820 in patients with advanced solid tumors

scientific article published on 2 April 2016

A phase I, dose-escalation study of the multitargeted receptor tyrosine kinase inhibitor, golvatinib, in patients with advanced solid tumors.

scientific article published on 2 October 2014

Advances in the management of melanoma: targeted therapy, immunotherapy and future directions ⬇️

scientific article published on November 1, 2012

An Adaptive Study to Determine the Optimal Dose of the Tablet Formulation of the PARP Inhibitor Olaparib

scientific article

Biomarkers of apoptosis

scientific article published on September 2008

Biomarkers of cell death applicable to early clinical trials

scientific article published on 27 March 2012

Catastrophic lower gastrointestinal complications following spinal surgery

scientific article published on September 2006

Effect of Food on the Pharmacokinetics of Olaparib after Oral Dosing of the Capsule Formulation in Patients with Advanced Solid Tumors

scientific article published on 6 June 2015

Erlotinib in combination with pemetrexed for patients with advanced non-small-cell lung cancer (NSCLC): a phase I dose-finding study

scientific article published on 5 May 2010

Favorable preliminary experience with etanercept in two patients with the hyperimmunoglobulinemia D and periodic fever syndrome

scientific article

First-in-Human Pharmacokinetic and Pharmacodynamic Study of the Dual m-TORC 1/2 Inhibitor AZD2014.

scientific article published on 24 March 2015

IAPs as a target for anticancer therapy.

scientific article published on December 2007

Malignant bowel obstruction in advanced ovarian cancer.

scientific article published on 18 January 2017

Multi-level evidence that circulating CK18 is a biomarker of tumour burden in colorectal cancer ⬇️

scientific article

Novel therapeutic targets in lung cancer: Inhibitor of apoptosis proteins from laboratory to clinic

scientific article published on 8 January 2007

Optimization of circulating biomarkers of obatoclax-induced cell death in patients with small cell lung cancer

scientific article

Phase I study to assess the safety and tolerability of olaparib in combination with bevacizumab in patients with advanced solid tumours

scientific article published on 5 January 2012

Phase I trial of AEG35156 administered as a 7-day and 3-day continuous intravenous infusion in patients with advanced refractory cancer

scientific article

Second-line treatment of postmenopausal women with advanced breast carcinoma

scientific article

Selumetinib in the treatment of non-small-cell lung cancer

scientific article published on 28 July 2016

Specific demonstration of drug-induced tumour cell apoptosis in human xenografts models using a plasma biomarker

scientific article published on January 2009

Targeted therapies in epithelial ovarian cancer

The TNF receptor-associated periodic syndrome (TRAPS): emerging concepts of an autoinflammatory disorder

scientific article

Utility of ctDNA to support patient selection for early phase clinical trials: the TARGET study

scientific article published on 22 April 2019

X-linked inhibitor of apoptosis protein as a therapeutic target

scientific article

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