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List of works by Michel Bernier

(R,R')-4'-methoxy-1-naphthylfenoterol targets GPR55-mediated ligand internalization and impairs cancer cell motility

scientific article published on 16 December 2013

(R,S)-Ketamine metabolites (R,S)-norketamine and (2S,6S)-hydroxynorketamine increase the mammalian target of rapamycin function.

scientific article

A chemical cross-linking method for the analysis of binding partners of heat shock protein-90 in intact cells.

scientific article

A peptide-based protein-tyrosine phosphatase inhibitor specifically enhances insulin receptor function in intact cells

scientific article published on 01 June 1996

A time to fast

scientific article published on 01 November 2018

Activation of heat shock factor 1 plays a role in pyrrolidine dithiocarbamate-mediated expression of the co-chaperone BAG3.

scientific article

Adipogenic signaling in rat white adipose tissue: modulation by aging and calorie restriction.

scientific article

Antitumor activity of (R,R')-4-methoxy-1-naphthylfenoterol in a rat C6 glioma xenograft model in the mouse

scientific article

Binding of manumycin A inhibits IkappaB kinase beta activity

scientific article

Breast cancer resistance protein (BCRP/ABCG2) localises to the nucleus in glioblastoma multiforme cells ⬇️

scientific article published on March 8, 2012

Cannabinoid receptor activation correlates with the proapoptotic action of the β2-adrenergic agonist (R,R')-4-methoxy-1-naphthylfenoterol in HepG2 hepatocarcinoma cells

scientific article

Capillary electrophoresis-laser-induced fluorescence (CE-LIF) assay for measurement of intracellular D-serine and serine racemase activity

scientific article

D-serine plasma concentration is a potential biomarker of (R,S)-ketamine antidepressant response in subjects with treatment-resistant depression

scientific article

Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance

scientific article published on 01 July 2021

Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β<sub>2</sub> adrenergic agonist

scientific article published on 07 March 2022

Determination of free and protein-bound glutathione in HepG2 cells using capillary electrophoresis with laser-induced fluorescence detection

scientific article

Differential expression of a novel seven transmembrane domain protein in epididymal fat from aged and diabetic mice

scientific article

Discrete region of the insulin receptor carboxyl terminus plays key role in insulin action

scientific article published on 01 April 2000

Elucidating the mechanisms by which disulfiram protects against obesity and metabolic syndrome

scientific article published on 21 July 2020

Endocrine regulation of G-protein subunit production in an animal model of type 2 diabetes mellitus.

scientific article

Exendin-4 improves glycemic control, ameliorates brain and pancreatic pathologies, and extends survival in a mouse model of Huntington's disease

scientific article

Filamin A expression correlates with proliferation and invasive properties of human metastatic melanoma tumors: implications for survival in patients.

scientific article

Filamin A-mediated down-regulation of the exchange factor Ras-GRF1 correlates with decreased matrix metalloproteinase-9 expression in human melanoma cells.

scientific article published on 27 March 2007

Glucagon-like peptide-1(7-36) amide (GLP-1) enhances insulin-stimulated glucose metabolism in 3T3-L1 adipocytes: one of several potential extrapancreatic sites of GLP-1 action.

scientific article

Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1

scientific article

Identification and characterization of estrogen receptor-related receptor alpha and gamma in human glioma and astrocytoma cells.

scientific article

Impact of pyrrolidine dithiocarbamate and interleukin-6 on mammalian target of rapamycin complex 1 regulation and global protein translation

scientific article

Initial synthesis and characterization of an alpha7 nicotinic receptor cellular membrane affinity chromatography column: effect of receptor subtype and cell type

scientific article

Initial synthesis and characterization of an immobilized heat shock protein 90 column for online determination of binding affinities

scientific article

Insertion of an N-terminal 6-aminohexanoic acid after the 7 amino acid position of glucagon-like peptide-1 produces a long-acting hypoglycemic agent.

scientific article

Interaction of filamin A with the insulin receptor alters insulin-dependent activation of the mitogen-activated protein kinase pathway.

scientific article published on 6 May 2003

Krüppel-like factor 4 inhibits proliferation by platelet-derived growth factor receptor beta-mediated, not by retinoic acid receptor alpha-mediated, phosphatidylinositol 3-kinase and ERK signaling in vascular smooth muscle cells

scientific journal article

Krüppel-like factor 4 promotes differentiation by transforming growth factor-beta receptor-mediated Smad and p38 MAPK signaling in vascular smooth muscle cells

scientific article

Ligand and protein fishing with heat shock protein 90 coated magnetic beads.

scientific article published on 12 August 2008

Membrane-bound CYB5R3 is a common effector of nutritional and oxidative stress response through FOXO3a and Nrf2.

scientific article

Metabolic remodelling of glucose, fatty acid and redox pathways in the heart of type 2 diabetic mice

scientific article published on 30 December 2018

Metformin improves healthspan and lifespan in mice

scientific article

Negative regulation of STAT3 protein-mediated cellular respiration by SIRT1 protein

scientific article

Nicotinic acetylcholine receptor antagonists alter the function and expression of serine racemase in PC-12 and 1321N1 cells

scientific article published on 04 September 2013

Nucleotide Excision Repair Is Not Required for the Antiapoptotic Function of Insulin-like Growth Factor 1 ⬇️

scientific article published on June 15, 1998

Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer's disease.

scientific article

Phosphatidylinositol 3-kinase requirement in activation of the ras/C-raf-1/MEK/ERK and p70(s6k) signaling cascade by the insulinomimetic agent vanadyl sulfate

scientific article published on 01 November 1999

Processing of human choriogonadotropin and its receptors by cultured pig Leydig cells. Role of cyclic AMP and protein synthesis

scientific article published on 01 March 1986

Pyrrolidine Dithiocarbamate Inhibits Interleukin-6 Signaling through Impaired STAT3 Activation and Association with Transcriptional Coactivators in Hepatocytes

scientific article published in Journal of Biological Chemistry

Pyrrolidine dithiocarbamate enhances hepatic glycogen synthesis and reduces FoxO1-mediated gene transcription in type 2 diabetic rats ⬇️

scientific article published on November 29, 2011

Regulation of glucose transporters and hexose uptake in 3T3-L1 adipocytes: glucagon-like peptide-1 and insulin interactions ⬇️

scientific article published on December 1, 1997

Regulation of gonadotropin receptors on cultured porcine Leydig and Sertoli cells: effect of potassium depletion

scientific article published on 01 June 1986

Resveratrol and Its Metabolites Bind to PPARs

scientific article

Resveratrol improves adipose insulin signaling and reduces the inflammatory response in adipose tissue of rhesus monkeys on high-fat, high-sugar diet.

scientific article published on October 2013

Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates.

scientific article

Resveratrol supplementation: Where are we now and where should we go?

scientific article

Reversible change in thiol redox status of the insulin receptor alpha-subunit in intact cells

scientific article published on 01 May 1999

Role of the pleckstrin homology domain of PLCgamma1 in its interaction with the insulin receptor

scientific article

S-glutathionylation impairs signal transducer and activator of transcription 3 activation and signaling.

scientific article published on 6 November 2008

S-glutathionylation of cysteine 99 in the APE1 protein impairs abasic endonuclease activity.

scientific article

SIRT1 synchs satellite cell metabolism with stem cell fate.

scientific article

SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass

scientific article

Sensing the insulin signaling pathway with an antibody array ⬇️

scientific article published on October 13, 2009

The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet

scientific article

The biarylpyrazole compound AM251 alters mitochondrial physiology via proteolytic degradation of ERRα

scientific article

The cannabinoid receptor inverse agonist AM251 regulates the expression of the EGF receptor and its ligands via destabilization of oestrogen-related receptor α protein

scientific article

The importance of the nine-amino acid C-terminal sequence of exendin-4 for binding to the GLP-1 receptor and for biological activity.

scientific article published in July 2003

The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma

scientific article

The search for antiaging interventions: from elixirs to fasting regimens

scientific article

Thiol-specific biotinylation of the insulin receptor in permeabilized cells enhances receptor function.

scientific article published on July 1995

Tyrosine 308 is necessary for ligand-directed Gs protein-biased signaling of β2-adrenoceptor

scientific article

What is hydroxynorketamine and what can it bring to neurotherapeutics?

scientific article

Wnt5A activates the calpain-mediated cleavage of filamin A

scientific article

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