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List of works by Leroy F. Liu

2,3,5,4'-Tetrahydroxystilbene-2-O-β-glucoside Isolated from Polygoni Multiflori Ameliorates the Development of Periodontitis

scientific article published on 18 July 2016

2,3-Dimethoxybenzo[i]phenanthridines: topoisomerase I-targeting anticancer agents

scientific article published on February 2003

26 S proteasome-mediated degradation of topoisomerase II cleavable complexes.

scientific article

A G-quadruplex stabilizer induces M-phase cell cycle arrest

scientific article published on 16 June 2009

A cruciform-dumbbell model for inverted dimer formation mediated by inverted repeats

scientific article published on August 1997

A novel role for ATM in regulating proteasome-mediated protein degradation through suppression of the ISG15 conjugation pathway

scientific article

A novel synthetic bipartite carrier protein for developing glycotope-based vaccines

scientific article published on October 22, 2012

A protease pathway for the repair of topoisomerase II-DNA covalent complexes

scientific article published on 13 September 2006

A protein factor from Xenopus oocytes with simian virus 40 large tumor antigen-like DNA supercoiling activity

scientific article

A replicational model for DNA recombination between direct repeats.

scientific article

A structure-activity relationship study of batracylin analogues

scientific article published on 01 June 1993

A terbenzimidazole that preferentially binds and conformationally alters structurally distinct DNA duplex domains: A potential mechanism for topoisomerase I poisoning

scientific article published on December 9, 1997

A ubiquitin-proteasome pathway for the repair of topoisomerase I-DNA covalent complexes.

scientific article

A vaccine targeted at CETP alleviates high fat and high cholesterol diet-induced atherosclerosis and non-alcoholic steatohepatitis in rabbit.

scientific article

ATP-dependent partitioning of the DNA template into supercoiled domains by Escherichia coli UvrAB

scientific article published on February 15, 1991

Acidic pH induces topoisomerase II-mediated DNA damage.

scientific article

Activation of topoisomerase II-mediated excision of chromosomal DNA loops during oxidative stress.

scientific article

Anti-proliferative and gene expression actions of resveratrol in breast cancer cells in vitro

scientific article

Antineoplastic activity of benzimidazo[1,2-b]-isoquinolines, indolo[2,3-b]quinolines, and pyridocarbazoles

scientific article published on 01 August 1994

Assembly of a polymeric chain of SUMO1 on human topoisomerase I in vitro

scientific article published on 20 January 2006

Association of eukaryotic DNA topoisomerase I with nucleosomes and chromosomal proteins.

scientific article

Autophagy regulates ageing in C. elegans.

scientific article published on 30 March 2007

Cell cycle-specific and transcription-related phosphorylation of mammalian topoisomerase I.

scientific article published on March 1995

Chemotherapeutics and radiation stimulate MHC class I expression through elevated interferon-beta signaling in breast cancer cells

scientific article

Correction: Novel leptin OB3 peptide-induced signaling and progression in thyroid cancers: Comparison with leptin.

scientific article published on May 2017

Crosstalk between integrin αvβ3 and ERα contributes to thyroid hormone-induced proliferation of ovarian cancer cells

scientific article

DNA damage-mediated apoptosis induced by selenium compounds.

scientific article published on 24 May 2003

DNA looping alters local DNA conformation during transcription

scientific article published on 01 June 1991

DNA minor groove binding-directed poisoning of human DNA topoisomerase I by terbenzimidazoles

scientific article published on 01 March 1998

DNA minor groove-binding ligands: a different class of mammalian DNA topoisomerase I inhibitors.

scientific article published on September 1993

DNA rearrangement mediated by inverted repeats.

scientific article

DNA topoisomerase I--targeted chemotherapy of human colon cancer in xenografts

scientific article published on 01 November 1989

DNA-DNA gyrase complex: the wrapping of the DNA duplex outside the enzyme

scientific article published on November 1, 1978

Design of antineoplastic agents based on the "2-phenylnaphthalene-type" structural pattern. 4. Synthesis and biological activity of 2-chloro-3-(substituted phenoxy)-1, 4-naphthoquinones and related 5,8-dihydroxy-1,4-naphthoquinones

scientific article published on 01 February 1999

Dietary isothiocyanate-induced apoptosis via thiol modification of DNA topoisomerase IIα.

scientific article

Differential poisoning of human and Aspergillus nidulans DNA topoisomerase I by bi- and terbenzimidazoles

scientific article published on 01 May 1997

Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation

scientific article

Eukaryotic DNA topoisomerases: two forms of type I DNA topoisomerases from HeLa cell nuclei

scientific article published on June 1, 1981

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

scientific article

ISG15 as a novel tumor biomarker for drug sensitivity.

scientific article published on June 2008

ISG15 disrupts cytoskeletal architecture and promotes motility in human breast cancer cells.

scientific article

Identification of a DNA supercoiling activity in Saccharomyces cerevisiae

scientific article published on October 11, 1992

In vivo mapping of DNA topoisomerase II-specific cleavage sites on SV40 chromatin.

scientific article

Inactivation of Cdc13p triggers MEC1-dependent apoptotic signals in yeast.

scientific article

Incompatibility of Escherichia coli rho mutants with plasmids is mediated by plasmid-specific transcription.

scientific article

Integration of simian virus 40 into cellular DNA occurs at or near topoisomerase II cleavage hot spots induced by VM-26 (teniposide).

scientific article published on October 1993

Interferon-β Signaling Contributes to Ras Transformation

scientific article published on August 29, 2011

Interlocking of plasmid DNAs due to Lac repressor-operator interaction.

scientific article

Inversion/dimerization of plasmids mediated by inverted repeats

scientific article published on 01 January 1999

Involvement of DNA topoisomerase I in transcription of human ribosomal RNA genes.

scientific article

Involvement of amino acids 361 to 364 of human topoisomerase I in camptothecin resistance and enzyme catalysis

scientific article published on 01 April 1997

Isodiospyrin as a novel human DNA topoisomerase I inhibitor.

scientific article published in November 2003

Knotted single-stranded DNA rings: a novel topological isomer of circular single-stranded DNA formed by treatment with Escherichia coli omega protein

scientific article published on 01 September 1976

Mechanism of action of camptothecin

scientific article published on 01 December 1996

Mechanisms of dihydrotestosterone action on resveratrol-induced anti-proliferation in breast cancer cells with different ERα status

scientific article published on 6 October 2015

Micrococcus luteus DNA gyrase: active components and a model for its supercoiling of DNA

scientific article published on May 1, 1978

Minor groove-directed and intercalative ligand-DNA interactions in the poisoning of human DNA topoisomerase I by protoberberine analogs

scientific article published on 01 October 1997

Newly replicated DNA is associated with DNA topoisomerase II in cultured rat prostatic adenocarcinoma cells

scientific article published on 01 July 1986

Nonhistone proteins HMG1and HMG2unwind DNA double helix

scientific article published on August 10, 1979

Novel leptin OB3 peptide-induced signaling and progression in thyroid cancers: Comparison with leptin.

scientific article published on 30 March 2016

Novel topologically knotted DNA from bacteriophage P4 capsids: studies with DNA topoisomerases

scientific article published on August 25, 1981

Nuclear translocation of cytochrome c during apoptosis.

scientific article published on 8 April 2004

Nucleolytic cleavage of the mixed lineage leukemia breakpoint cluster region during apoptosis.

scientific article published on 13 June 2001

Overexpression of RNase H partially complements the growth defect of an Escherichia coli delta topA mutant: R-loop formation is a major problem in the absence of DNA topoisomerase I

scientific article

Phosphorylation of Ubc9 by Cdk1 enhances SUMOylation activity

scientific article

Polygonum multiflorum Decreases Airway Allergic Symptoms in a Murine Model of Asthma

scientific article published in February 2016

Potent antitumor 9-anilinoacridines and acridines bearing an alkylating N-mustard residue on the acridine chromophore: synthesis and biological activity.

scientific article published on June 2006

Processing of topoisomerase I cleavable complexes into DNA damage by transcription.

scientific article

Protection of DNA ends by telomeric 3' G-tail sequences

scientific article published on 04 May 2007

Recognition sites of eukaryotic DNA topoisomerase I: DNA nucleotide sequencing analysis of topo I cleavage sites on SV40 DNA.

scientific article published on April 1982

Role of DNA topoisomerase IIbeta in neurite outgrowth.

scientific article

Role of topoisomerase IIbeta in the expression of developmentally regulated genes.

scientific article published on 21 August 2006

Roles of DNA topoisomerase II isozymes in chemotherapy and secondary malignancies.

scholarly article

SUMO-1 conjugation to topoisomerase I: A possible repair response to topoisomerase-mediated DNA damage

scientific article

Single-stranded DNA induces ataxia telangiectasia mutant (ATM)/p53-dependent DNA damage and apoptotic signals.

scientific article

Site-specific topoisomerase I-mediated DNA cleavage induced by nogalamycin: a potential role of ligand-induced DNA bending at a distal site

scientific article published on 01 August 2000

Specific stimulation of recA-independent plasmid recombination by a DNA sequence at a distance.

scientific article

Syntheses and biological evaluation of topoisomerase I-targeting agents related to 11-[2-(N,N-dimethylamino)ethyl]-2,3-dimethoxy-8,9-methylenedioxy-11H-isoquino[4,3-c]cinnolin-12-one (ARC-31).

scientific article

Synthesis and pharmacological evaluation of isoindolo[1,2-b]quinazolinone and isoindolo[2,1-a]benzimidazole derivatives related to the antitumor agent batracylin

scientific article published on 01 September 1994

TOR regulates cell death induced by telomere dysfunction in budding yeast

scientific article

Targeting mammalian target of rapamycin (mTOR) for health and diseases.

scientific article published on 15 December 2006

Tetrac downregulates β-catenin and HMGA2 to promote the effect of resveratrol in colon cancer

scientific article published on 18 December 2017

The combination of tetraiodothyroacetic acid and cetuximab inhibits cell proliferation in colorectal cancers with different K-ras status

scientific article published on 12 March 2016

The cytokine-cosmc signaling axis upregulates the tumor-associated carbohydrate antigen Tn.

scientific article published on 17 August 2016

The role of autophagy in mitochondria maintenance: characterization of mitochondrial functions in autophagy-deficient S. cerevisiae strains

scientific article published on 09 July 2007

The topoisomerase IIbeta circular clamp arrests transcription and signals a 26S proteasome pathway

scholarly article

Therapeutic applications of resveratrol and its derivatives on periodontitis.

scientific article published on 30 August 2017

Topoisomerase II is a structural component of mitotic chromosome scaffolds.

scientific article

Topoisomerase IIbeta is required for proper retinal development and survival of postmitotic cells

scientific article published on 15 February 2014

Topoisomerases: novel therapeutic targets in cancer chemotherapy

scientific article published on 01 May 1988

Topological approaches to studies of protein-mediated looping of DNA in vivo

scientific article published on January 1, 1992

Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53

scientific article

Transcription generates positively and negatively supercoiled domains in the template.

scientific article

Transcription-driven supercoiling of DNA: direct biochemical evidence from in vitro studies

scientific article published on 01 January 1989

Tumor cell death induced by topoisomerase-targeting drugs.

scientific article

Ubiquitin-dependent destruction of topoisomerase I is stimulated by the antitumor drug camptothecin

scientific article published on 01 September 1997

recA-independent and recA-dependent intramolecular plasmid recombination. Differential homology requirement and distance effect

scientific article