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List of works by Rick L. Tarleton

A Heuristic method for assigning a false-discovery rate for protein identifications from Mascot database search results

scientific article

A combined shotgun and multidimensional proteomic analysis of the insoluble subproteome of the obligate thermophile, Geobacillus thermoleovorans T80.

scientific article published in September 2006

A framework for ontology-based question answering with application to parasite immunology

scientific article

A modified drug regimen clears active and dormant trypanosomes in mouse models of Chagas disease

scientific article published on 01 October 2020

A monoclonal antibody to alpha tubulin recognizes host cell and Trypanosoma cruzi tubulins.

scientific article

A new liquid chromatography/tandem mass spectrometric approach for the identification of class I major histocompatibility complex associated peptides that eliminates the need for bioassays

scientific article published on 01 January 1999

A semantic problem solving environment for integrative parasite research: identification of intervention targets for Trypanosoma cruzi.

scientific article

A semi-quantitative GeLC-MS analysis of temporal proteome expression in the emerging nosocomial pathogen Ochrobactrum anthropi

scientific article published on January 2007

A systematic review of high quality diagnostic tests for Chagas disease

scientific article

Analysis of the Trypanosoma cruzi cyclophilin gene family and identification of Cyclosporin A binding proteins.

scientific article

Biology of tegument associated IgG-Fc and C3 receptors inSchistosoma mansoni

scientific article published on 01 August 1986

CD8+ T cells in Trypanosoma cruzi infection

scientific article

CD8+ T cells in Trypanosoma cruzi infection

scientific article published on 29 July 2009

CD8+ T cells specific for immunodominant trans-sialidase epitopes contribute to control of Trypanosoma cruzi infection but are not required for resistance

scientific article published on 07 June 2010

CD8+ T-Cell responses to Trypanosoma cruzi are highly focused on strain-variant trans-sialidase epitopes

scientific article

CRISPR-Cas9-mediated single-gene and gene family disruption in Trypanosoma cruzi

scientific article

Chagas Disease: A Solvable Problem, Ignored

scientific article published on 11 August 2016

Chagas disease and the london declaration on neglected tropical diseases

scientific article published on 9 October 2014

Chagas disease: a role for autoimmunity? ⬇️

scientific article published on October 1, 2003

Changes in Trypanosoma cruzi-specific immune responses after treatment: surrogate markers of treatment efficacy

scientific article

Characterization of cytokine production in murine Trypanosoma cruzi infection by in situ immunocytochemistry: lack of association between susceptibility and type 2 cytokine production.

scientific article

Chemokine receptor 7 (CCR7)-expression and IFNγ production define vaccine-specific canine T-cell subsets

scientific article published on 7 February 2015

Chromosome level assembly of the hybrid Trypanosoma cruzi genome

scientific article

Chronic human infection with Trypanosoma cruzi drives CD4+ T cells to immune senescence

scientific article published on 19 August 2009

Construction and use of a multi-competitor gene for quantitative RT-PCR using existing primer sets

article

Correction for Ekanayake et al., "Epigenetic Regulation of Transcription and Virulence in Trypanosoma cruzi by O-Linked Thymine Glucosylation of DNA".

scientific article

Cutting Edge: Augmenting Muscle MHC Expression Enhances Systemic Pathogen Control at the Expense of T Cell Exhaustion

scientific article published on 26 June 2020

Differentiation of trypanosomatid species by hybridization to selected rRNA probes.

scientific article published on April 1993

Drug-induced cure drives conversion to a stable and protective CD8+ T central memory response in chronic Chagas disease

scientific article

Eliminating Chagas disease: challenges and a roadmap

scientific article

Endogenous CD4(+) CD25(+) regulatory T cells have a limited role in the control of Trypanosoma cruzi infection in mice

scientific article published on 13 November 2006

Epigenetic regulation of transcription and virulence in Trypanosoma cruzi by O-linked thymine glucosylation of DNA.

scientific article

Evaluation of high efficiency gene knockout strategies for Trypanosoma cruzi

scientific article

Evidence for the role of vacuolar soluble pyrophosphatase and inorganic polyphosphate in Trypanosoma cruzi persistence

scientific article published on 30 September 2013

Frequency of IFNγ-producing T cells correlates with seroreactivity and activated T cells during canine Trypanosoma cruzi infection

scientific article published on 23 January 2014

Frequency of interferon- gamma -producing T cells specific for Trypanosoma cruzi inversely correlates with disease severity in chronic human Chagas disease

scientific article published on 17 February 2004

Generation of Trypanosoma cruzi-specific CD8+ T-cell immunity is unaffected by the absence of type I interferon signaling

scientific article

Generation, specificity, and function of CD8+ T cells in Trypanosoma cruzi infection

scientific article published in October 2004

Genetic immunization elicits antigen-specific protective immune responses and decreases disease severity in Trypanosoma cruzi infection

scientific article

Genetic immunization with LYT1 or a pool of trans-sialidase genes protects mice from lethal Trypanosoma cruzi infection

scientific article

Glycoproteomics ofTrypanosoma cruziTrypomastigotes Using Subcellular Fractionation, Lectin Affinity, and Stable Isotope Labeling

High throughput selection of effective serodiagnostics for Trypanosoma cruzi infection

scientific article

High variation in immune responses and parasite phenotypes in naturally acquired Trypanosoma cruzi infection in a captive non-human primate breeding colony in Texas, USA

scientific article published on 31 March 2021

Highly competent, non-exhausted CD8+ T cells continue to tightly control pathogen load throughout chronic Trypanosoma cruzi infection

scientific article published on 12 November 2018

Identification of contractile vacuole proteins in Trypanosoma cruzi

scientific article (publication date: 2011)

Immune system recognition of Trypanosoma cruzi

scientific article published on 24 July 2007

Impact of aetiological treatment on conventional and multiplex serology in chronic Chagas disease

scientific article

In vitro and in vivo high-throughput assays for the testing of anti-Trypanosoma cruzi compounds

scientific article

Inducible nitric oxide synthase is not essential for control of Trypanosoma cruzi infection in mice

scientific article

Inhibitory receptors are expressed by Trypanosoma cruzi-specific effector T cells and in hearts of subjects with chronic Chagas disease

scientific article

Initial induction of immunity, followed by suppression of responses to parasite antigens during Trypanosoma cruzi infection of mice.

scientific article

Insufficient TLR activation contributes to the slow development of CD8+ T cell responses in Trypanosoma cruzi infection

scientific article

Is Chagas disease really the "new HIV/AIDS of the Americas"?

scientific article

Kinetoplastids: Trypanosoma cruzi (Chagas disease)

Kinetoplastids: related protozoan pathogens, different diseases

scientific article published on April 2008

Knockout of the dhfr-ts gene in Trypanosoma cruzi generates attenuated parasites able to confer protection against a virulent challenge

scientific article

Limited role for CD4+ T-cell help in the initial priming of Trypanosoma cruzi-specific CD8+ T cells

scientific article published on 16 October 2006

Measurement of parasite-specific immune responsesin vitro: evidence for suppression of the antibody response toTrypanosoma cruzi

article

Methodological advances in drug discovery for Chagas disease

scientific article

Microarray profiling of gene expression during trypomastigote to amastigote transition in Trypanosoma cruzi

scientific article

Multidimensional analysis of the insoluble sub-proteome of Oceanobacillus iheyensis HTE831, an alkaliphilic and halotolerant deep-sea bacterium isolated from the Iheya ridge

article

Multidimensional proteomic analysis of the soluble subproteome of the emerging nosocomial pathogen Ochrobactrum anthropi

article

New approaches in vaccine development for parasitic infections

scientific article

New, combined, and reduced dosing treatment protocols cure Trypanosoma cruzi infection in mice

scientific article published on 14 August 2013

Oral exposure to Trypanosoma cruzi elicits a systemic CD8⁺ T cell response and protection against heterotopic challenge

scientific article

Perpetual expression of PAMPs necessary for optimal immune control and clearance of a persistent pathogen

scientific article

Persistent production of inflammatory and anti-inflammatory cytokines and associated MHC and adhesion molecule expression at the site of infection and disease in experimental Trypanosoma cruzi infections.

scientific article published in November 1996

Perturbed T cell IL-7 receptor signaling in chronic Chagas disease.

scientific article

Polyfunctional T cell responses in children in early stages of chronic Trypanosoma cruzi infection contrast with monofunctional responses of long-term infected adults

scientific article

Potential new clinical therapies for Chagas disease

scientific article published on 09 April 2014

Proteins with Glycosylphosphatidylinositol (GPI) Signal Sequences Have Divergent Fates during a GPI Deficiency

scientific article published in Journal of Biological Chemistry

Proteomic analysis of the Trypanosoma cruzi ribosomal proteins

scientific article published on 24 February 2009

Protozoan persister-like cells and drug treatment failure

scientific article published on 23 August 2019

Rapid quantitation of Trypanosoma cruzi in host tissue by real-time PCR.

scientific article published on June 2003

Reaching for the Holy Grail: insights from infection/cure models on the prospects for vaccines for Trypanosoma cruzi infection

scientific article published on 28 April 2015

Recombination-driven generation of the largest pathogen repository of antigen variants in the protozoan Trypanosoma cruzi

scientific article

Report of the 2nd Chagas Drug Discovery Consortium meeting, held on 3 November 2010; Atlanta GA, USA.

scientific article published on 19 July 2011

Spontaneous dormancy protects Trypanosoma cruzi during extended drug exposure.

scientific article

Strain-specific genome evolution in Trypanosoma cruzi, the agent of Chagas disease

scientific article published on 28 January 2021

TGF-beta regulates pathology but not tissue CD8+ T cell dysfunction during experimental Trypanosoma cruzi infection

scientific article

The Genome Sequence of Trypanosoma cruzi, Etiologic Agent of Chagas Disease

scientific article

The Significance of Discordant Serology in Chagas Disease: Enhanced T-Cell Immunity to Trypanosoma cruzi in Serodiscordant Subjects

scientific article published on 15 September 2017

The Trypanosoma cruzi flagellum is discarded via asymmetric cell division following invasion and provides early targets for protective CD8⁺ T cells ⬇️

scientific article

The Trypanosoma cruzi proteome.

scientific article

The challenges of Chagas Disease-- grim outlook or glimmer of hope

scientific article

The role of T cells in Trypanosoma cruzi infections

scientific article published on 01 January 1995

The steady-state transcriptome of the four major life-cycle stages of Trypanosoma cruzi

scientific article

Transgenic parasites accelerate drug discovery

scientific article published on 23 January 2012

Treatment Success in Trypanosoma cruzi Infection Is Predicted by Early Changes in Serially Monitored Parasite-Specific T and B Cell Responses

scientific article published on 29 April 2016

Trypanoside, anti-tuberculosis, leishmanicidal, and cytotoxic activities of tetrahydrobenzothienopyrimidines

scientific article

Trypanosoma cruzi infection in MHC-deficient mice: further evidence for the role of both class I- and class II-restricted T cells in immune resistance and disease

Trypanosoma cruzi modulates the profile of memory CD8+ T cells in chronic Chagas' disease patients

scientific article published on 23 January 2006

Trypanosoma cruzi-specific immune responses in subjects from endemic areas of Chagas disease of Argentina

scientific article

Widespread, focal copy number variations (CNV) and whole chromosome aneuploidies in Trypanosoma cruzi strains revealed by array comparative genomic hybridization

scientific article

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