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List of works by Takeshi Nabe

A New Model of Experimental Allergic Rhinitis Using Japanese Cedar Pollen in Guinea Pigs

scientific article published on November 1, 1997

A new CysLT1 and CysLT2 receptors-mediated anaphylaxis guinea pig model.

scientific article published on 8 March 2017

A tiaramide derivative, 5-chloro-3-(4-hydroxypiperadinocarbonylmethyl)benzothiazoline-2-one (HPR-611), a potent inhibitor of anaphylactic chemical mediator release--a distinctive feature from disodium cromoglycate

scientific article published on 01 December 1992

Ability of teicoplanin and vancomycin to induce contraction of, and histamine release from, pulmonary tissue of humans, monkeys and guinea pigs

scientific article published in 1999

Absence of nasal blockage in a Japanese cedar pollen-induced allergic rhinitis model mouse.

scientific article

Acquired nasal hyperresponsiveness aggravates antigen-induced rhinitis in the guinea pig.

scientific article

Analysis of major paralogs encoding the Fra a 1 allergen based on their organ-specificity in Fragaria × ananassa

scientific article published on 25 November 2017

Antigen-specific airway IL-33 production depends on FcγR-mediated incorporation of the antigen by alveolar macrophages in sensitized mice.

scientific article published on 22 March 2018

Arachidonate 5-lipoxygenase and cyclooxygenase metabolites from guinea pig eosinophils and macrophages

scientific article published on 01 July 2000

Augmentation of spontaneous cough by enalapril through up-regulation of bradykinin B1 receptors in guinea pigs.

scientific article published in August 2003

Carrageenans can regulate the pulmonary absorption of antiasthmatic drugs and their retention in the rat lung tissues without any membrane damage.

scientific article published in April 2005

Complement C3a regulates late asthmatic response and airway hyperresponsiveness in mice

scientific article published on 14 August 2009

Complement C3a-induced IL-17 plays a critical role in an IgE-mediated late-phase asthmatic response and airway hyperresponsiveness via neutrophilic inflammation in mice

scientific article published on 25 April 2012

Complete dependence on CD4+ cells in late asthmatic response, but limited contribution of the cells to airway remodeling in sensitized mice

scientific article published on 21 July 2011

CysLT2 receptor activation is involved in LTC4-induced lung air-trapping in guinea pigs.

scientific article published on 22 November 2016

Cysteinyl leukotriene-dependent interleukin-5 production leading to eosinophilia during late asthmatic response in guinea-pigs

scientific article published in April 2002

Deficiency of n-6 polyunsaturated fatty acids is mainly responsible for atopic dermatitis-like pruritic skin inflammation in special diet-fed hairless mice

scientific article published on 01 April 2013

Delayed Type Allergic Itch-Associated Response Induced by Toluene-2,4-diisocyanate in Hairless Mice

scientific article published on September 1, 2003

Delayed-type asthmatic response induced by repeated intratracheal exposure to toluene-2,4-diisocyanate in guinea pigs

scientific article published on 25 April 2005

Detection of new antigenic proteins in Japanese cedar pollen.

scientific article published in June 2006

Development of cigarette smoke solution- and lipopolysaccharide-induced pulmonary emphysema in guinea pigs.

scientific article published in January 2010

Development of numerous nerve fibers in the epidermis of hairless mice with atopic dermatitis-like pruritic skin inflammation

scientific article published on 03 July 2007

Development of pollen-induced allergic rhinitis with early and late phase nasal blockage in guinea pigs

scientific article published on September 1, 1998

Dietary deficiencies of unsaturated fatty acids and starch cause atopic dermatitis-like pruritus in hairless mice.

scientific article published in February 2015

Discovery of Gemilukast (ONO-6950), a Dual CysLT1 and CysLT2 Antagonist As a Therapeutic Agent for Asthma

scientific article

Effect of Ganoderma lucidum on pollen-induced biphasic nasal blockage in a guinea pig model of allergic rhinitis

article

Effect of TA-270, a novel quinolinone derivative, on antigen-induced nasal blockage in a guinea pig model of allergic rhinitis.

scientific article published on 9 November 2008

Effect of a peroxynitrite scavenger, a manganese-porphyrin compound on airway remodeling in a murine asthma.

scientific article published on 25 February 2013

Effect of local nasal immunotherapy on nasal blockage in pollen-induced allergic rhinitis of Guinea pigs.

scientific article published in November 2008

Effect of oral immunotherapy on nasal blockage in experimental allergic rhinitis

scientific article published on 02 August 2005

Effects of KP-496, a novel dual antagonist of leukotriene D(4) and thromboxane A (2) receptors on nasal blockage in guinea pig models of allergic rhinitis.

scientific article published in June 2008

Effects of TAK-427 on acute nasal symptoms and nasal obstruction in guinea pig model of experimental allergic rhinitis.

scientific article published in August 2003

Effects of multiple dexamethasone treatments on aggravation of allergic conjunctivitis associated with mast cell hyperplasia

scientific article

Eicosapentaenoic acid ethyl ester ameliorates atopic dermatitis-like symptoms in special diet-fed hairless mice, partly by restoring covalently bound ceramides in the stratum corneum

scientific article published on 2 February 2018

Endothelin-1 induces release of histamine and leukotriene C4 from mouse bone marrow-derived mast cells

scientific article published on 01 May 1994

Endothelin-1, one of the most potent histamine releasers in mouse peritoneal mast cells

scientific article published on 01 November 1994

Establishment and characterization of a murine model for allergic asthma using allergen-specific IgE monoclonal antibody to study pathological roles of IgE

scientific article published on 20 October 2011

Exposure to multiwalled carbon nanotubes and allergen promotes early- and late-phase increases in airway resistance in mice

scientific article published on 01 January 2012

Expression of CysLT2 receptors in asthma lung, and their possible role in bronchoconstriction.

scientific article published on 3 June 2015

Group IVA phospholipase A2 participates in the progression of hepatic fibrosis.

scientific article

Hypomorphic mutation in the hairless gene accelerates pruritic atopic skin caused by feeding a special diet to mice

scientific article published on 01 June 2016

IL-17A promotes the exacerbation of IL-33-induced airway hyperresponsiveness by enhancing neutrophilic inflammation via CXCR2 signaling in mice

scientific article published on 20 January 2014

IgE/antigen-mediated enhancement of IgE production is a mechanism underlying the exacerbation of airway inflammation and remodelling in mice

scientific article published on 01 January 2015

Immediate inhibition by oral l-ephedrine of passive cutaneous anaphylaxis of rats: indirect inhibition of anaphylactic chemical mediator release from the mast cell

scientific article published on 01 October 2000

Important role of neutrophils in the late asthmatic response in mice

scientific article published on 30 April 2011

Important roles of tachykinins in the development of allergic nasal hyperresponsiveness in guinea-pigs

scientific article published on 04 September 2008

Increased expression of CysLT2 receptors in the lung of asthmatic mice and role in allergic responses

scientific article published on 22 March 2018

Induction of a late asthmatic response associated with airway inflammation in mice

scientific article published on 22 September 2005

Inhibition of hematopoietic prostaglandin D synthase improves allergic nasal blockage in guinea pigs.

scientific article published on 10 May 2011

Inhibitory effect of ONO-1078 on specific binding of peptide leukotrienes to human lung crude membrane

scientific article published on 01 September 1994

Interleukin (IL)-33: new therapeutic target for atopic diseases.

scientific article published on 10 September 2014

Interleukin-33 and alveolar macrophages contribute to the mechanisms underlying the exacerbation of IgE-mediated airway inflammation and remodelling in mice

scientific article published on 01 June 2013

Intratracheal dosing with disodium cromoglycate inhibits late asthmatic response by attenuating eicosanoid production in guinea pigs

scientific article

Intratracheal sensitization/challenge-induced biphasic asthmatic response and airway hyperresponsiveness in guinea pigs

scientific article published on January 2010

Involvement of chymase in allergic conjunctivitis of guinea pigs

scientific article published on May 28, 2013

Involvement of galectin-9 in guinea pig allergic airway inflammation.

scientific article published on May 2007

Longitudinal study of effects of oral dosage of Bifidobacterium bifidum G9-1 on Japanese cedar pollen-induced allergic nasal symptoms in guinea pigs.

scientific article

MCI-826 is a potent and selective antagonist of peptide leukotrienes (p-LTs) and has characteristics distinctive from those of FPL 55712

scientific article published on 01 September 1992

Markedly increased nasal blockage by intranasal leukotriene D4 in an experimental allergic rhinitis model: contribution of dilated mucosal blood vessels.

scientific article published in June 2001

Mast cell hyperplasia induced by multiple challenge with cedar pollen in sensitised guinea pigs.

scientific article

Murine asthma model focusing on IL-33

scientific article published on 01 January 2017

Nanomolar concentrations of neuropeptides induce histamine release from peritoneal mast cells of a substrain of Wistar rats

scientific article published on 01 June 1999

No involvement of interleukin-5 or eosinophils in experimental allergic rhinitis in guinea pigs.

scientific article

Oral beta-stimulants can inhibit passive cutaneous anaphylaxis in rats through an indirect inhibitory mechanism: possible involvement of afferent and efferent nervous system via gastric beta2-adrenoceptor stimulation

scientific article published on 01 December 2000

Participation of neuropeptides in antigen-induced contraction of guinea pig bronchi via NK(2) but not NK(1) receptor stimulation

scientific article published on 01 May 2000

Pharmacokinetic interference of doxorubicin with tolbutamide due to reduced metabolic clearance with increased serum unbound fraction in rats

scientific article published on 16 July 2019

Pharmacological analyses of mechanisms underlying nasal blockage using a guinea-pig model of allergic rhinitis

scientific article published in May 2005

Polycyclic aromatic hydrocarbons aggravate antigen-induced nasal blockage in experimental allergic rhinitis.

scientific article published on 6 November 2007

Preparation of 2- and 4-(2-alkylcarbamoyl-1-methylvinyl)-7-alkyloxybenzo[b]furans having potent antagonistic activity against human leukotriene B4 BLT1 and/or BLT2 receptors

scientific article published in November 2004

Production of interleukin (IL)-33 in the lungs during multiple antigen challenge-induced airway inflammation in mice, and its modulation by a glucocorticoid

scientific article published on 20 March 2015

Regulation of allergic airway inflammation by adoptive transfer of CD4+ T cells preferentially producing IL-10

scientific article published on 29 June 2017

Regulation of macrophage differentiation and polarization by group IVC phospholipase A₂

scientific article published on 15 November 2011

Regulatory role of antigen-induced interleukin-10, produced by CD4(+) T cells, in airway neutrophilia in a murine model for asthma

scientific article published on 23 December 2011

Repeated Antigen Inhalation-Induced Reproducible Early and Late Asthma in Guinea Pigs

scientific article published on 01 September 1997

Repeated antigen inhalations alter chemical mediators that cause asthmatic obstruction in guinea pigs

scientific article published on 01 September 1999

Reproducible biphasic cutaneous edema induced by topical and repeated application of antigen in sensitized mice

scientific article published on 01 April 2000

Roles of basophils and mast cells infiltrating the lung by multiple antigen challenges in asthmatic responses of mice

scientific article published on May 2013

Semaphorin 7A plays a critical role in IgE-mediated airway inflammation in mice

scientific article published on 02 July 2015

Significant role of peptide leukotrienes (p-LTs) in the antigen-induced contractions of human and guinea pig lung parenchymas and bronchi or tracheas in vitro

scientific article published on November 1, 1992

Synergism between cysteinyl leukotrienes and thromboxane A2 to induce allergic late phase nasal blockage in guinea pigs.

scientific article published in October 2004

Synthesis of 2-, 4- and 5-(2-alkylcarbamoyl-1-methylvinyl)-7-alkyloxybenzo[b]furans and their leukotriene B4 receptor antagonistic activity

scientific article published on 16 May 2005

Thymic stromal lymphopoietin-induced interleukin-17A is involved in the development of IgE-mediated atopic dermatitis-like skin lesions in mice

scientific article published on 24 September 2015

Topical ocular treatment with monoclonal antibody Fab fragments targeting Japanese cedar pollen Cry j 1 inhibits Japanese cedar pollen-induced allergic conjunctivitis in mice.

scientific article published on 21 January 2017

Tumor Necrosis Factor Alpha-Mediated Asthma?

scientific article published on September 25, 2012

l-Ephedrine is a major constituent of Mao-Bushi-Saishin-To, one of the formulas of Chinese medicine, which shows immediate inhibition after oral administration of passive cutaneous anaphylaxis in rats.

scientific article published in August 2000