List of works - Athi N. Naganathan

A Disordered Loop Mediates Heterogeneous Unfolding of an Ordered Protein by Altering the Native Ensemble

scientific article published on 06 August 2020

A General Mechanism for the Propagation of Mutational Effects in Proteins

scientific article published on 13 December 2016

A Universal Pattern in the Percolation and Dissipation of Protein Structural Perturbations.

scientific article

A binding cooperativity switch driven by synergistic structural swelling of an osmo-regulatory protein pair

scientific article published on 30 April 2019

A disorder-induced domino-like destabilization mechanism governs the folding and functional dynamics of the repeat protein IκBα

scientific article

A rapid, ensemble and free energy based method for engineering protein stabilities

scientific article published on 11 April 2013

A self-consistent structural perturbation approach for determining the magnitude and extent of allosteric coupling in proteins

scientific article

Are Protein Folding Intermediates the Evolutionary Consequence of Functional Constraints?

scientific article published on 07 January 2015

Bridging Experiments and Native-Centric Simulations of a Downhill Folding Protein

scientific article published on 16 November 2015

Coarse-grained models of protein folding as detailed tools to connect with experiments

Coarse-grained representation of protein flexibility. Foundations, successes, and shortcomings.

scientific article published on January 2011

Controlling Structure and Dimensions of a Disordered Protein via Mutations

scientific article published on 26 September 2019

Determining denaturation midpoints in multiprobe equilibrium protein folding experiments

scientific article published on 10 June 2008

Direct Measurement of Barrier Heights in Protein Folding

scientific article published on 01 December 2005

Direct observation of downhill folding of lambda-repressor in a microfluidic mixer

scientific article published on September 2009

Dynamics of one-state downhill protein folding

scholarly article

Dynamics, energetics, and structure in protein folding

scientific article

Energetic and topological determinants of a phosphorylation-induced disorder-to-order protein conformational switch

scientific article published on 01 November 2015

Engineering Order and Cooperativity in a Disordered Protein

scientific article published on 30 April 2019

Entropic Control of an Excited Folded-Like Conformation in a Disordered Protein Ensemble

Estimation of protein folding free energy barriers from calorimetric data by multi-model Bayesian analysis.

scientific article published on 19 July 2011

Evidence for the sequential folding mechanism in RNase H from an ensemble-based model.

scientific article

Exploiting the downhill folding regime via experiment

scientific article published on 13 October 2008

Extracting the Hidden Distributions Underlying the Mean Transition State Structures in Protein Folding

scientific article published on 22 March 2018

Folding RaCe: a robust method for predicting changes in protein folding rates upon point mutations

scientific article published on 16 February 2015

Graded Structural Polymorphism in a Bacterial Thermosensor Protein

scientific article

Imprints of function on the folding landscape: functional role for an intermediate in a conserved eukaryotic binding protein

scientific article published on April 2015

Insight into the specificity and severity of pathogenic mechanisms associated with missense mutations through experimental and structural perturbation analyses

Insights into protein folding mechanisms from large scale analysis of mutational effects

scientific article

Modern Analysis of Protein Folding by Differential Scanning Calorimetry.

scientific article

Modulation of allosteric coupling by mutations: from protein dynamics and packing to altered native ensembles and function

scientific article published on 28 September 2018

Navigating the downhill protein folding regime via structural homologues

scientific article published on August 2010

Non-specific DNA-driven quinary interactions promote structural transitions in proteins

scientific article published on 27 May 2020

Prediction of change in protein unfolding rates upon point mutations in two state proteins

scientific article

Predictions from an Ising-like Statistical Mechanical Model on the Dynamic and Thermodynamic Effects of Protein Surface Electrostatics

scientific article published on 22 October 2012

Predictive Modeling of Protein Folding Thermodynamics, Mutational Effects and Free-Energy Landscapes

Protein folding kinetics: barrier effects in chemical and thermal denaturation experiments

scientific article published on 10 April 2007

Protein plasticity driven by disorder and collapse governs the heterogeneous binding of CytR to DNA.

scientific article

Quantifying Protein Disorder through Measures of Excess Conformational Entropy

scientific article

Quantitative prediction of protein folding behaviors from a simple statistical model

scientific article

Robustness of downhill folding: guidelines for the analysis of equilibrium folding experiments on small proteins.

scientific article published in May 2005

Scaling of folding times with protein size

scientific article published in January 2005

Switching Protein Conformational Substates by Protonation and Mutation

The conformational landscape of an intrinsically disordered DNA-binding domain of a transcription regulator

The native ensemble and folding of a protein molten-globule: functional consequence of downhill folding

scientific article

The protein folding transition-state ensemble from a Gō-like model.

scientific article published on 21 July 2011

Thermally versus Chemically Denatured Protein States

scientific article published on 16 May 2019

Thermodynamics of downhill folding: multi-probe analysis of PDD, a protein that folds over a marginal free energy barrier

scientific article published on 21 July 2014

Toward a quantitative description of microscopic pathway heterogeneity in protein folding

scientific article published on 26 July 2017

Tunable order-disorder continuum in protein-DNA interactions

Tuning the Continuum of Structural States in the Native Ensemble of a Regulatory Protein

scientific article published on 27 March 2017

pStab: Prediction of Stable Mutants, Unfolding Curves, Stability Maps and Protein Electrostatic Frustration

scientific article published on 28 October 2017

List of works by Athi N. Naganathan

A Disordered Loop Mediates Heterogeneous Unfolding of an Ordered Protein by Altering the Native Ensemble

A General Mechanism for the Propagation of Mutational Effects in Proteins

A Universal Pattern in the Percolation and Dissipation of Protein Structural Perturbations.

A binding cooperativity switch driven by synergistic structural swelling of an osmo-regulatory protein pair

A disorder-induced domino-like destabilization mechanism governs the folding and functional dynamics of the repeat protein IκBα

A rapid, ensemble and free energy based method for engineering protein stabilities

A self-consistent structural perturbation approach for determining the magnitude and extent of allosteric coupling in proteins

Are Protein Folding Intermediates the Evolutionary Consequence of Functional Constraints?

Bridging Experiments and Native-Centric Simulations of a Downhill Folding Protein

Coarse-grained models of protein folding as detailed tools to connect with experiments

Coarse-grained representation of protein flexibility. Foundations, successes, and shortcomings.

Controlling Structure and Dimensions of a Disordered Protein via Mutations

Determining denaturation midpoints in multiprobe equilibrium protein folding experiments

Direct Measurement of Barrier Heights in Protein Folding

Direct observation of downhill folding of lambda-repressor in a microfluidic mixer

Dynamics of one-state downhill protein folding

Dynamics, energetics, and structure in protein folding

Energetic and topological determinants of a phosphorylation-induced disorder-to-order protein conformational switch

Engineering Order and Cooperativity in a Disordered Protein

Entropic Control of an Excited Folded-Like Conformation in a Disordered Protein Ensemble

Estimation of protein folding free energy barriers from calorimetric data by multi-model Bayesian analysis.

Evidence for the sequential folding mechanism in RNase H from an ensemble-based model.

Exploiting the downhill folding regime via experiment

Extracting the Hidden Distributions Underlying the Mean Transition State Structures in Protein Folding

Folding RaCe: a robust method for predicting changes in protein folding rates upon point mutations

Graded Structural Polymorphism in a Bacterial Thermosensor Protein

Imprints of function on the folding landscape: functional role for an intermediate in a conserved eukaryotic binding protein

Insight into the specificity and severity of pathogenic mechanisms associated with missense mutations through experimental and structural perturbation analyses

Insights into protein folding mechanisms from large scale analysis of mutational effects

Modern Analysis of Protein Folding by Differential Scanning Calorimetry.

Modulation of allosteric coupling by mutations: from protein dynamics and packing to altered native ensembles and function

Navigating the downhill protein folding regime via structural homologues

Non-specific DNA-driven quinary interactions promote structural transitions in proteins

Prediction of change in protein unfolding rates upon point mutations in two state proteins

Predictions from an Ising-like Statistical Mechanical Model on the Dynamic and Thermodynamic Effects of Protein Surface Electrostatics

Predictive Modeling of Protein Folding Thermodynamics, Mutational Effects and Free-Energy Landscapes

Protein folding kinetics: barrier effects in chemical and thermal denaturation experiments

Protein plasticity driven by disorder and collapse governs the heterogeneous binding of CytR to DNA.

Quantifying Protein Disorder through Measures of Excess Conformational Entropy

Quantitative prediction of protein folding behaviors from a simple statistical model

Robustness of downhill folding: guidelines for the analysis of equilibrium folding experiments on small proteins.

Scaling of folding times with protein size

Switching Protein Conformational Substates by Protonation and Mutation

The conformational landscape of an intrinsically disordered DNA-binding domain of a transcription regulator

The native ensemble and folding of a protein molten-globule: functional consequence of downhill folding

The protein folding transition-state ensemble from a Gō-like model.

Thermally versus Chemically Denatured Protein States

Thermodynamics of downhill folding: multi-probe analysis of PDD, a protein that folds over a marginal free energy barrier

Toward a quantitative description of microscopic pathway heterogeneity in protein folding

Tunable order-disorder continuum in protein-DNA interactions

Tuning the Continuum of Structural States in the Native Ensemble of a Regulatory Protein

pStab: Prediction of Stable Mutants, Unfolding Curves, Stability Maps and Protein Electrostatic Frustration