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List of works by Dirk Arnold

(Neo-)adjuvant treatments in colorectal cancer.

scientific article

A meta-analysis comparing the efficacy of four 5-HT3-receptor antagonists for acute chemotherapy-induced emesis

scientific article

A phase II study of catumaxomab administered intra- and postoperatively as part of a multimodal approach in primarily resectable gastric cancer

scientific article published on 12 September 2014

A phase II trial of gemcitabine in combination with 5-fluorouracil (24-hour) and folinic acid in patients with chemonaive advanced pancreatic cancer

scientific article published on 01 October 2000

A prospective multicenter phase II study evaluating multimodality treatment of patients with peritoneal carcinomatosis arising from appendiceal and colorectal cancer: the COMBATAC trial

scientific article

A randomised phase II study of irinotecan in combination with 5-FU/FA compared with irinotecan alone as second-line treatment of patients with metastatic colorectal carcinoma

scientific article

Adjuvant chemotherapy with gemcitabine and cisplatin compared to observation after curative intent resection of cholangiocarcinoma and muscle invasive gallbladder carcinoma (ACTICCA-1 trial) - a randomized, multidisciplinary, multinational phase III

scientific article published on 31 July 2015

Adjuvant therapy in colon cancer

scientific article published on 23 April 2010

Administration of chemotherapy by an arteriovenous fistula in a patient with metastatic rectal cancer after life-threatening, port thrombosis-associated cava superior syndrome. An option for patients without possibility of peripheral or central veno

scientific article published on 12 July 2012

Aflibercept Plus FOLFIRI vs. Placebo Plus FOLFIRI in Second-Line Metastatic Colorectal Cancer: a Post Hoc Analysis of Survival from the Phase III VELOUR Study Subsequent to Exclusion of Patients who had Recurrence During or Within 6 Months of Comple

scientific article

Anal cancer: ESMO-ESSO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

scientific article published on 6 July 2014

Anal cancer: ESMO-ESSO-ESTRO clinical practice guidelines for diagnosis, treatment and follow-up.

scientific article published on October 2014

Anal cancer: ESMO-ESSO-ESTRO clinical practice guidelines for diagnosis, treatment and follow-up.

scientific article published on 16 June 2014

Analysis of bevacizumab-based preoperative radiochemotherapy in patients with locally advanced rectal cancer on surgery-associated spectrum of complications

scientific article published on 04 December 2013

Baseline and On-Treatment Markers Determining Prognosis of First-Line Chemotherapy in Combination with Bevacizumab in Patients with Metastatic Colorectal Cancer.

scientific article published on 18 January 2017

Bevacizumab in combination with sequential high-dose chemotherapy in solid cancer, a feasibility study.

scientific article published on 15 March 2010

Bevacizumab in first-line treatment of elderly patients with metastatic colorectal cancer: German community-based observational cohort study results

scientific article

Bevacizumab plus chemotherapy as first-line treatment for patients with metastatic colorectal cancer: results from a large German community-based observational cohort study

scientific article published on 13 October 2014

Bevacizumab plus chemotherapy continued beyond first progression in patients with metastatic colorectal cancer previously treated with bevacizumab plus chemotherapy: ML18147 study KRAS subgroup findings

scientific article

Biliary cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published on 01 September 2016

Biomarkers for Cetuximab-Based Neoadjuvant Radiochemotherapy in Locally Advanced Rectal Cancer

scientific article published on 10 May 2011

Breast plasmacytoma

Capecitabine and bevacizumab for non-resectable metastatic colorectal cancer patients: final results from phase II AIO KRK 0105 trial

scientific article

Capecitabine in the routine first-line treatment of elderly patients with advanced colorectal cancer--results from a non-interventional observation study.

scientific article published in January 2015

Capecitabine/irinotecan or capecitabine/oxaliplatin in combination with bevacizumab is effective and safe as first-line therapy for metastatic colorectal cancer: a randomized phase II study of the AIO colorectal study group.

scientific article

Central venous catheter complications during home parenteral nutrition: a prospective pilot study of 481 patients with more than 30,000 catheter days

scientific article published on 23 October 2008

Cetuximab in combination with weekly 5-fluorouracil/folinic acid and oxaliplatin (FUFOX) in untreated patients with advanced colorectal cancer: a phase Ib/II study of the AIO GI Group.

scientific article published on 25 April 2008

Challenges in the multidisciplinary management of stage IV colon and rectal cancer.

scientific article published on 05 September 2014

Clinical management of localized colon cancer with capecitabine

scientific article

Clinical trial designs for rare diseases: studies developed and discussed by the International Rare Cancers Initiative ⬇️

scientific article

Clinicopathological factors influencing outcome in metastatic colorectal cancer patients treated with fluoropyrimidine and bevacizumab maintenance treatment vs observation: an individual patient data meta-analysis of two phase 3 trials.

scientific article published on 9 November 2017

Colorectal carcinoma: the management of polyps, (neo)adjuvant therapy, and the treatment of metastases

scientific article

Complete remission in a colon cancer patient with a large, irresectable liver metastasis after XELOX/cetuximab/bevacizumab treatment.

scientific article

Concurrent chemoradiation of metastases with capecitabine and oxaliplatin and 3D-CRT in patients with oligometastatic colorectal cancer: results of a phase I study

scientific article

Continuation of bevacizumab after first progression in metastatic colorectal cancer (ML18147): a randomised phase 3 trial

scientific article

Continuation of regional chemotherapy of hepatic neoplasms despite occlusion of the hepatic artery-report of four cases

scientific article published in July 2002

Corrigendum to "2nd St. Gallen EORTC Gastrointestinal Cancer Conference: Consensus recommendations on controversial issues in the primary treatment of rectal cancer" [Eur J Cancer 63 (August 2016) 11-24].

scientific article published on 4 October 2016

Critical evaluation of the scientific content in clinical practice guidelines

scientific article published on 29 January 2015

Current challenges in optimizing systemic therapy for patients with pancreatic cancer: expert perspectives from the Australasian Gastrointestinal Trials Group (AGITG) with invited international faculty.

scientific article published on 18 August 2017

Current opinion on optimal systemic treatment for metastatic colorectal cancer: outcome of the ACTG/AGITG expert meeting ECCO 2013.

scientific article

Delivering precision medicine in oncology today and in future-the promise and challenges of personalised cancer medicine: a position paper by the European Society for Medical Oncology (ESMO).

scientific article

Diagnosis and treatment of liver metastases from primary colorectal tumour

scientific article

Docetaxel, oxaliplatin and capecitabine (TEX regimen) in patients with metastatic gastric or gastro-esophageal cancer: results of a multicenter phase I/II study.

scientific article published on 12 September 2013

ECCO Essential Requirements for Quality Cancer Care: Colorectal Cancer. A critical review ⬇️

scientific article published on 08 December 2016

EGF61 polymorphism predicts complete pathologic response to cetuximab-based chemoradiation independent of KRAS status in locally advanced rectal cancer patients

scientific article

ESMO Consensus Guidelines for management of patients with colon and rectal cancer. A personalized approach to clinical decision making

scientific article published on 01 October 2012

ESMO consensus guidelines for the management of patients with metastatic colorectal cancer.

scientific article published on 5 July 2016

Early colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

scientific article

Economic outcomes of sequences which include monoclonal antibodies against vascular endothelial growth factor and/or epidermal growth factor receptor for the treatment of unresectable metastatic colorectal cancer.

scientific article published on 3 December 2013

Effect of Application and Intensity of Bevacizumab-based Maintenance After Induction Chemotherapy With Bevacizumab for Metastatic Colorectal Cancer: A Meta-analysis

scientific article published on 18 December 2015

Effect of KRAS codon13 mutations in patients with advanced colorectal cancer (advanced CRC) under oxaliplatin containing chemotherapy. Results from a translational study of the AIO colorectal study group

scientific article

Effect of Neoadjuvant Chemotherapy Followed by Surgical Resection on Survival in Patients With Limited Metastatic Gastric or Gastroesophageal Junction Cancer: The AIO-FLOT3 Trial

scientific article published on 27 April 2017

Efficacy of oxaliplatin plus capecitabine or infusional fluorouracil/leucovorin in patients with metastatic colorectal cancer: a pooled analysis of randomized trials

scientific article

Epidermal growth factor receptor tyrosine kinase inhibitors: present and future role in gastrointestinal cancer treatment: a review.

scientific article published on June 2006

Familial risk-colorectal cancer: ESMO Clinical Practice Guidelines

scientific article

First-line treatment of pancreatic cancer patients with the combination of 5-fluorouracil/folinic acid plus gemcitabine: a multicenter phase II trial by the CONKO-study group

scientific article published on 15 March 2011

Gastric cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†

scientific article published in September 2016

Gastric cancer: ESMO-ESSO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article

Gastric cancer: ESMO–ESSO–ESTRO clinical practice guidelines for diagnosis, treatment and follow-up

scientific article published in May 2014

Gastric cancer†: ESMO–ESSO–ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published in January 2014

Gefitinib in Combination with 5-Fluorouracil (5-FU)/Folinic Acid and Irinotecan in Patients with 5-FU/Oxaliplatin- Refractory Colorectal Cancer: A Phase I/II Study of the Arbeitsgemeinschaft für Internistische Onkologie (AIO)

German S3-guideline "Diagnosis and treatment of esophagogastric cancer"

scientific article

Improving patient outcomes with regorafenib for metastatic colorectal cancer - patient selection, dosing, patient education, prophylaxis, and management of adverse events

scientific article published on 12 May 2015

Inflammatory lesions of the peritoneum mimic carcinomatosis after treatment with intravenous chemotherapy and intraperitoneal catumaxomab.

scientific article published on 23 May 2011

Integrating patient reported measures as predictive parameters into decisionmaking about palliative chemotherapy: a pilot study.

scientific article

Intramuscular manifestation of non-Hodgkin lymphoma and myeloma: prevalence, clinical signs, and computed tomography features

scientific article published in February 2010

Intraperitoneal bevacizumab for control of malignant ascites due to advanced-stage gastrointestinal cancers: A multicentre double-blind, placebo-controlled phase II study - AIO SUP-0108.

scientific article

Maintenance strategies after first-line oxaliplatin plus fluoropyrimidine plus bevacizumab for patients with metastatic colorectal cancer (AIO 0207): a randomised, non-inferiority, open-label, phase 3 trial

scientific article

Maintenance treatment in metastatic colorectal cancer - Authors' reply.

scientific article published in December 2015

Maintenance treatment with the immunomodulator MGN1703, a Toll-like receptor 9 (TLR9) agonist, in patients with metastatic colorectal carcinoma and disease control after chemotherapy: a randomised, double-blind, placebo-controlled trial.

scientific article

Metastatic colorectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article

Methylated free-circulating HPP1 DNA is an early response marker in patients with metastatic colorectal cancer.

scientific article published on 25 January 2017

Multicenter phase II trial of chemoradiation with oxaliplatin for rectal cancer

scientific article published on 01 January 2007

New Developments in the Second-Line Treatment of Metastatic Colorectal Cancer: Potential Place in Therapy ⬇️

scientific article published on June 1, 2013

Oesophageal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published on 01 September 2016

Oesophageal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

scientific article

Optimizing the use of sunitinib in metastatic renal cell carcinoma: an update from clinical practice

scientific article published on October 2010

Outcome according to KRAS-, NRAS- and BRAF-mutation as well as KRAS mutation variants: pooled analysis of five randomized trials in metastatic colorectal cancer by the AIO colorectal cancer study group

scientific article

Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial

scientific article published on 15 July 2015

Oxaliplatin-based first-line chemotherapy is associated with improved overall survival compared to first-line treatment with irinotecan-based chemotherapy in patients with metastatic colorectal cancer - Results from a prospective cohort study

scientific article published on 20 April 2015

Oxaliplatin: a review of approved uses.

scientific article published on January 2012

PTEN deletion is rare but often homogeneous in gastric cancer

scientific article published on 25 May 2012

Paclitaxel as weekly second-line therapy in patients with advanced pancreatic carcinoma

scientific article published in September 2000

Parenteral nutrition support for patients with pancreatic cancer. Results of a phase II study

scientific article

Pathologic response to bevacizumab-containing chemotherapy in patients with colorectal liver metastases and its correlation with survival ⬇️

scientific article published on 09 August 2012

Peri-operative chemotherapy for the treatment of resectable liver metastases from colorectal cancer: A systematic review and meta-analysis of randomized trials

scientific article

Phase I study of gemcitabine in combination with cisplatin, 5-fluorouracil and folinic acid in patients with advanced esophageal cancer

scientific article

Phase I-II trial of cetuximab, capecitabine, oxaliplatin, and radiotherapy as preoperative treatment in rectal cancer

scientific article published on 19 September 2007

Phase I/II trial of capecitabine and oxaliplatin in combination with bevacizumab and imatinib in patients with metastatic colorectal cancer: AIO KRK 0205.

scientific article published on 20 August 2013

Phase II study of cetuximab in combination with docetaxel in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck after platinum-containing therapy: a multicenter study of the Arbeitsgemeinschaft Internistische Onko

scientific article published on 26 February 2013

Phase II trial of preoperative radiochemotherapy with concurrent bevacizumab, capecitabine and oxaliplatin in patients with locally advanced rectal cancer

scientific article published on 15 April 2013

Port Catheter Insufficiency: Incidence and Clinical-Radiological Correlations

article

Preclinical evaluation of ZD1839 alone or in combination with oxaliplatin in a panel of human tumor cell lines -- implications for clinical use.

scientific article published on 9 September 2005

Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial

scientific article

Prevalence and patterns of renal involvement in imaging of malignant lymphoproliferative diseases

scientific article published on 27 January 2012

Primary and secondary breast lymphoma: prevalence, clinical signs and radiological features

scientific article

Prognostic and predictive value of primary tumour side in patients with RAS wild-type metastatic colorectal cancer treated with chemotherapy and EGFR directed antibodies in six randomized trials.

scientific article published on 12 April 2017

Prospective, open, multi-centre phase I/II trial to assess safety and efficacy of neoadjuvant radiochemotherapy with docetaxel and oxaliplatin in patients with adenocarcinoma of the oesophagogastric junction.

scientific article

Quality of life assessment in patients with metastatic colorectal cancer receiving maintenance therapy after first-line induction treatment: a preplanned analysis of the phase III AIO KRK 0207 trial

scientific article

Rectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published on 01 July 2017

Review article: panitumumab--a fully human anti-EGFR monoclonal antibody for treatment of metastatic colorectal cancer.

scientific article published on August 2008

S3 guidelines for colorectal carcinoma: results of an evidence-based consensus conference on February 6/7, 2004 and June 8/9, 2007 (for the topics IV, VI and VII).

scientific article published on 13 January 2010

Safety and efficacy of weekly 5-fluorouracil/folinic acid/oxaliplatin/irinotecan in the first-line treatment of gastrointestinal cancer.

scientific article

Second St. Gallen European Organisation for Research and Treatment of Cancer Gastrointestinal Cancer Conference: consensus recommendations on controversial issues in the primary treatment of rectal cancer

scientific article

Sequential neoadjuvant chemoradiotherapy (CRT) followed by curative surgery vs. primary surgery alone for resectable, non-metastasized pancreatic adenocarcinoma: NEOPA- a randomized multicenter phase III study (NCT01900327, DRKS00003893, ISRCTN82191

scientific article

Sequential or combination chemotherapy for a patient with mCRC?

scientific article published in January 2008

Skeletal muscle metastases: primary tumours, prevalence, and radiological features

scientific article published on 26 August 2009

Specific treatment situations in metastatic colorectal cancer

scientific article

The integration of targeted agents into systemic therapy of metastatic colorectal cancer.

scientific article published on September 2006

The role of biological agents in the resection of colorectal liver metastases.

scientific article published on August 2012

The role of gemcitabine alone and in combination in the treatment of pancreatic cancer

scientific article

The role of peri-operative treatment in resectable liver metastases of colorectal cancer

scientific article

The role of relative lymphocyte count as a biomarker for the effect of catumaxomab on survival in malignant ascites patients: results from a phase II/III study

scientific article published on 08 April 2014

Time course of safety and efficacy of aflibercept in combination with FOLFIRI in patients with metastatic colorectal cancer who progressed on previous oxaliplatin-based therapy.

scientific article published on 14 November 2014

Treatment approach in patients with hyperbilirubinemia secondary to liver metastases in gastrointestinal malignancies: a case series and review of literature.

scientific article published on 17 March 2016

Treatment decisions in metastatic colorectal cancer - Beyond first and second line combination therapies.

scientific article

Treatment of rectal cancer

scientific article published on 23 April 2010

Treatment with bevacizumab and FOLFOXIRI in patients with advanced colorectal cancer: presentation of two novel trials (CHARTA and PERIMAX) and review of the literature

scientific article

Update on capecitabine in colorectal cancer

scientific article published on October 2006

Update on optimal treatment for metastatic colorectal cancer from the ACTG/AGITG expert meeting: ECCO 2015.

scientific article published on 24 March 2016

Weekly administration of sagopilone (ZK-EPO), a fully synthetic epothilone, in patients with refractory solid tumours: results of a phase I trial.

scientific article published on 22 September 2009

When wishful thinking leads to a misty-eyed appraisal: the story of the adjuvant colon cancer trials with edrecolomab.

scientific article published on 9 March 2009

[ASCO-update 2015 - highlights of the 51. meeting of the american society of clinical oncology/ASCO 2015]

scientific article published on 08 February 2016

[Capecitabine plus oxaliplatin compared with fluorouracil and folinic acid as adjuvant therapy for stage III colon cancer]

scientific article published on 01 February 2012

[Clinical trials and personalized medicine in oncology?]

scientific article published on 16 September 2010

[Colorectal carcinoma--primary treatment in case of advanced metastization].

scientific article

[Gastrointestinal tumors--interdisciplinary discussion over new data].

scientific article published on 27 April 2011

[Long-term sequelae of cancer survivors]

scientific article published on 01 April 2012

[Palliative treatment for colorectal cancer].

scientific article published on 22 June 2009

[Surgical and perioperative therapy of liver metastases]

scientific article published on 14 November 2008

[Systemic treatment of peritoneal metastases].

scientific article

[Treatment of nonresectable liver metastases]

scientific article published on 14 November 2008

[Update S3-guideline "colorectal cancer" 2008]

scientific article published on 01 August 2008

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