List of works - Christopher T Lohans

13C-Carbamylation as a mechanistic probe for the inhibition of class D β-lactamases by avibactam and halide ions

scientific article published on 5 July 2017

19 F NMR Monitoring of Reversible Protein Post-Translational Modifications: Class D β-Lactamase Carbamylation and Inhibition

scientific article published on 20 August 2019

A Fluorescence-Based Assay for Screening β-Lactams Targeting the Mycobacterium tuberculosis Transpeptidase LdtMt2

scientific article published on 08 November 2019

A New Mechanism for β-Lactamases: Class D Enzymes Degrade 1β-Methyl Carbapenems through Lactone Formation.

scientific article

Biochemical and biophysical analyses of hypoxia sensing prolyl hydroxylases from Dictyostelium discoideum and Toxoplasma gondii

scientific article published on 15 September 2020

Biochemical, structural, and genetic characterization of tridecaptin A₁, an antagonist of Campylobacter jejuni.

scientific article

Correction to "Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library"

scientific article published on 28 October 2019

Crystallographic analyses of isoquinoline complexes reveal a new mode of metallo-β-lactamase inhibition.

scientific article published in May 2017

Cyclic Boronates Inhibit All Classes of β-Lactamases ⬇️

scientific article published on 23 January 2017

Development of Class IIa Bacteriocins as Therapeutic Agents

scientific article

Draft Genome Sequence of the Bacteriocin-Producing Strain Enterococcus faecium M3K31, Isolated from Griffon Vultures (Gyps fulvus subsp. fulvus).

scientific article

Draft Genome Sequences of Paenibacillus polymyxa NRRL B-30509 and Paenibacillus terrae NRRL B-30644, Strains from a Poultry Environment That Produce Tridecaptin A and Paenicidins

scientific article

Expansion of base excision repair compensates for a lack of DNA repair by oxidative dealkylation in budding yeast

scientific article published on 18 July 2019

Genetic determinants of reutericyclin biosynthesis in Lactobacillus reuteri

scientific article published on 9 January 2015

IFPTarget: A Customized Virtual Target Identification Method Based on Protein-Ligand Interaction Fingerprinting Analyses.

scientific article

Identification and three-dimensional structure of carnobacteriocin XY, a class IIb bacteriocin produced by Carnobacteria.

scientific article published on 9 April 2017

Inhibition of a viral prolyl hydroxylase

scientific article published on 23 January 2019

Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials

scientific article published on 11 September 2017

NMR-filtered virtual screening leads to non-metal chelating metallo-β-lactamase inhibitors

scientific article published on 14 December 2016

New Delhi Metallo-β-Lactamase 1 Catalyzes Avibactam and Aztreonam Hydrolysis.

scientific article published on 2 October 2017

Non-Hydrolytic β-Lactam Antibiotic Fragmentation by l,d-Transpeptidases and Serine β-Lactamase Cysteine Variants

scientific article published on 21 January 2019

Nuclear Magnetic Resonance Solution Structures of Lacticin Q and Aureocin A53 Reveal a Structural Motif Conserved among Leaderless Bacteriocins with Broad-Spectrum Activity

scientific article

Purification and characterization of antimicrobial peptides from fish isolate Carnobacterium maltaromaticum C2: Carnobacteriocin X and carnolysins A1 and A2.

scientific article

Roles of 2-oxoglutarate oxygenases and isopenicillin N synthase in β-lactam biosynthesis

scientific article published on 01 August 2018

Selective Inhibitors of a Human Prolyl Hydroxylase (OGFOD1) Involved in Ribosomal Decoding

scientific article published on 08 January 2019

Solution Structure of Enterocin HF, an Antilisterial Bacteriocin Produced by Enterococcus faecium M3K31

scientific article

Solution Structures of Phenol-Soluble Modulins α1, α3, and β2, Virulence Factors from Staphylococcus aureus

scientific article

Solution structure of acidocin B, a circular bacteriocin produced by Lactobacillus acidophilus M46.

scientific article published on 13 February 2015

Solution structures of the linear leaderless bacteriocins enterocin 7A and 7B resemble carnocyclin A, a circular antimicrobial peptide

scientific article

Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate.

scientific article published on 18 April 2017

Structural characterization of the highly cyclized lantibiotic paenicidin A via a partial desulfurization/reduction strategy

scientific article

Structural characterization of thioether-bridged bacteriocins

scientific article published on 11 September 2013

Structural/mechanistic insights into the efficacy of non-classical β-lactamase inhibitors against extensively drug resistant Stenotrophomonas maltophilia clinical isolates. ⬇️

scientific article published on 6 September 2017

Structure and biosynthesis of carnolysin, a homologue of enterococcal cytolysin with D-amino acids.

scientific article

Structure-Activity Relationship and Crystallographic Studies on 4-Hydroxypyrimidine HIF Prolyl Hydroxylase Domain Inhibitors

scientific article published on 03 December 2019

Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library

article

Studies on enmetazobactam clarify mechanisms of widely used β-lactamase inhibitors

scientific article published on 29 April 2022

Studies on the inhibition of AmpC and other β-lactamases by cyclic boronates

scientific article published in April 2019

Studies on tridecaptin B(1), a lipopeptide with activity against multidrug resistant Gram-negative bacteria

scientific article published on June 2015

Substitution of a conserved disulfide in the type IIa bacteriocin, leucocin A, with L-leucine and L-serine residues: effects on activity and three-dimensional structure

scientific article

Synthesis and Structure–Activity Relationship Studies of N-Terminal Analogues of the Antimicrobial Peptide Tridecaptin A1

scientific article published on 30 January 2014

Targeting the Mycobacterium tuberculosis transpeptidase LdtMt2 with cysteine-reactive inhibitors including ebselen

scientific article published on 01 August 2019

The activity of bacteriocins from Carnobacterium maltaromaticum UAL307 against gram-negative bacteria in combination with EDTA treatment

scientific article published on 7 February 2011

List of works by Christopher T Lohans

13C-Carbamylation as a mechanistic probe for the inhibition of class D β-lactamases by avibactam and halide ions

19 F NMR Monitoring of Reversible Protein Post-Translational Modifications: Class D β-Lactamase Carbamylation and Inhibition

A Fluorescence-Based Assay for Screening β-Lactams Targeting the Mycobacterium tuberculosis Transpeptidase LdtMt2

A New Mechanism for β-Lactamases: Class D Enzymes Degrade 1β-Methyl Carbapenems through Lactone Formation.

Biochemical and biophysical analyses of hypoxia sensing prolyl hydroxylases from Dictyostelium discoideum and Toxoplasma gondii

Biochemical, structural, and genetic characterization of tridecaptin A₁, an antagonist of Campylobacter jejuni.

Correction to "Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library"

Crystallographic analyses of isoquinoline complexes reveal a new mode of metallo-β-lactamase inhibition.

Cyclic Boronates Inhibit All Classes of β-Lactamases ⬇️

Development of Class IIa Bacteriocins as Therapeutic Agents

Draft Genome Sequence of the Bacteriocin-Producing Strain Enterococcus faecium M3K31, Isolated from Griffon Vultures (Gyps fulvus subsp. fulvus).

Draft Genome Sequences of Paenibacillus polymyxa NRRL B-30509 and Paenibacillus terrae NRRL B-30644, Strains from a Poultry Environment That Produce Tridecaptin A and Paenicidins

Expansion of base excision repair compensates for a lack of DNA repair by oxidative dealkylation in budding yeast

Genetic determinants of reutericyclin biosynthesis in Lactobacillus reuteri

IFPTarget: A Customized Virtual Target Identification Method Based on Protein-Ligand Interaction Fingerprinting Analyses.

Identification and three-dimensional structure of carnobacteriocin XY, a class IIb bacteriocin produced by Carnobacteria.

Inhibition of a viral prolyl hydroxylase

Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials

NMR-filtered virtual screening leads to non-metal chelating metallo-β-lactamase inhibitors

New Delhi Metallo-β-Lactamase 1 Catalyzes Avibactam and Aztreonam Hydrolysis.

Non-Hydrolytic β-Lactam Antibiotic Fragmentation by l,d-Transpeptidases and Serine β-Lactamase Cysteine Variants

Nuclear Magnetic Resonance Solution Structures of Lacticin Q and Aureocin A53 Reveal a Structural Motif Conserved among Leaderless Bacteriocins with Broad-Spectrum Activity

Purification and characterization of antimicrobial peptides from fish isolate Carnobacterium maltaromaticum C2: Carnobacteriocin X and carnolysins A1 and A2.

Roles of 2-oxoglutarate oxygenases and isopenicillin N synthase in β-lactam biosynthesis

Selective Inhibitors of a Human Prolyl Hydroxylase (OGFOD1) Involved in Ribosomal Decoding

Solution Structure of Enterocin HF, an Antilisterial Bacteriocin Produced by Enterococcus faecium M3K31

Solution Structures of Phenol-Soluble Modulins α1, α3, and β2, Virulence Factors from Staphylococcus aureus

Solution structure of acidocin B, a circular bacteriocin produced by Lactobacillus acidophilus M46.

Solution structures of the linear leaderless bacteriocins enterocin 7A and 7B resemble carnocyclin A, a circular antimicrobial peptide

Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate.

Structural characterization of the highly cyclized lantibiotic paenicidin A via a partial desulfurization/reduction strategy

Structural characterization of thioether-bridged bacteriocins

Structural/mechanistic insights into the efficacy of non-classical β-lactamase inhibitors against extensively drug resistant Stenotrophomonas maltophilia clinical isolates. ⬇️

Structure and biosynthesis of carnolysin, a homologue of enterococcal cytolysin with D-amino acids.

Structure-Activity Relationship and Crystallographic Studies on 4-Hydroxypyrimidine HIF Prolyl Hydroxylase Domain Inhibitors

Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library

Studies on enmetazobactam clarify mechanisms of widely used β-lactamase inhibitors

Studies on the inhibition of AmpC and other β-lactamases by cyclic boronates

Studies on tridecaptin B(1), a lipopeptide with activity against multidrug resistant Gram-negative bacteria

Substitution of a conserved disulfide in the type IIa bacteriocin, leucocin A, with L-leucine and L-serine residues: effects on activity and three-dimensional structure

Synthesis and Structure–Activity Relationship Studies of N-Terminal Analogues of the Antimicrobial Peptide Tridecaptin A1

Targeting the Mycobacterium tuberculosis transpeptidase LdtMt2 with cysteine-reactive inhibitors including ebselen

The activity of bacteriocins from Carnobacterium maltaromaticum UAL307 against gram-negative bacteria in combination with EDTA treatment