List of works - Ernesto Moreno

A shift from N-glycolyl- to N-acetyl-sialic acid in the GM3 ganglioside impairs tumor development in mouse lymphocytic leukemia cells.

scientific article published on 2 April 2013

A view on EGFR-targeted therapies from the oncogene-addiction perspective.

scientific article published on 26 April 2013

AMDock: a versatile graphical tool for assisting molecular docking with Autodock Vina and Autodock4

scientific article published on 16 September 2020

An interferon gamma release assay specific for Histoplasma capsulatum to detect asymptomatic infected individuals: A proof of concept study

scientific article published on 01 August 2019

Blocking IL-2 Signal In Vivo with an IL-2 Antagonist Reduces Tumor Growth through the Control of Regulatory T Cells

scientific article published on 04 April 2018

Crystal structure of an anti-ganglioside antibody, and modelling of the functional mimicry of its NeuGc-GM3 antigen by an anti-idiotypic antibody

scientific article

Delineation of the epitope recognized by an antibody specific for N-glycolylneuraminic acid-containing gangliosides.

scientific article published in 1998

Do rotamer libraries reproduce the side-chain conformations of peptidic ligands from the PDB?

scientific article

EGFR-Targeting as a Biological Therapy: Understanding Nimotuzumab's Clinical Effects

scientific article published on 18 April 2011

EGFR-targeting therapy as an evolving concept: learning from nimotuzumab clinical development.

scientific article

Engineering the binding site of an antibody against N-glycolyl GM3: from functional mapping to novel anti-ganglioside specificities.

scientific article

Gangliosides, Ab1 and Ab2 antibodies I. Towards a molecular dissection of an idiotype-anti-idiotype system

scientific article

Gangliosides, Ab1 and Ab2 antibodies II. Light versus heavy chain: An idiotype-anti-idiotype case study.

scientific article published on 18 April 2006

Geometric and chemical patterns of interaction in protein--ligand complexes and their application in docking

scientific article published on 01 April 2002

Human IL-2 mutein with higher antitumor efficacy than wild type IL-2.

scientific article published on 15 May 2013

KBE009: An antimalarial bestatin-like inhibitor of the Plasmodium falciparum M1 aminopeptidase discovered in an Ugi multicomponent reaction-derived peptidomimetic library.

scientific article

Light-chain shuffling results in successful phage display selection of functional prokaryotic-expressed antibody fragments to N-glycolyl GM3 ganglioside

scientific article

Nimotuzumab and cetuximab block ligand-independent EGF receptor signaling efficiently at different concentrations.

scientific article published on September 2011

Nimotuzumab, an antitumor antibody that targets the epidermal growth factor receptor, blocks ligand binding while permitting the active receptor conformation

scientific article

Non-classical binding of a polyreactive α-type anti-idiotypic antibody to B cells.

scientific article published on 16 October 2010

Predicting the right spacing between protein immobilization sites on self-assembled monolayers to optimize ligand binding

scientific article

Redefinition of the carbohydrate specificity of Erythrina corallodendron lectin based on solid-phase binding assays and molecular modeling of native and recombinant forms obtained by site-directed mutagenesis

scientific article published on 01 April 1997

Setting up a large set of protein-ligand PDB complexes for the development and validation of knowledge-based docking algorithms

scientific article

Structure and molecular interactions of a unique antitumor antibody specific for N-glycolyl GM3

scientific article

Structure of the Fab fragment of the anti-murine EGFR antibody 7A7 and exploration of its receptor binding site

scientific article

Switching on cytotoxicity by a single mutation at the heavy chain variable region of an anti-ganglioside antibody ⬇️

scientific article published on April 1, 2011

The anti-CD6 antibody itolizumab provides clinical benefit without lymphopenia in rheumatoid arthritis patients: results from a 6-month, open-label Phase I clinical trial.

scientific article published on 30 September 2017

gmx_MMPBSA: A New Tool to Perform End-State Free Energy Calculations with GROMACS

scientific article published on 29 September 2021

List of works by Ernesto Moreno

A shift from N-glycolyl- to N-acetyl-sialic acid in the GM3 ganglioside impairs tumor development in mouse lymphocytic leukemia cells.

A view on EGFR-targeted therapies from the oncogene-addiction perspective.

AMDock: a versatile graphical tool for assisting molecular docking with Autodock Vina and Autodock4

An interferon gamma release assay specific for Histoplasma capsulatum to detect asymptomatic infected individuals: A proof of concept study

Blocking IL-2 Signal In Vivo with an IL-2 Antagonist Reduces Tumor Growth through the Control of Regulatory T Cells

Crystal structure of an anti-ganglioside antibody, and modelling of the functional mimicry of its NeuGc-GM3 antigen by an anti-idiotypic antibody

Delineation of the epitope recognized by an antibody specific for N-glycolylneuraminic acid-containing gangliosides.

Do rotamer libraries reproduce the side-chain conformations of peptidic ligands from the PDB?

EGFR-Targeting as a Biological Therapy: Understanding Nimotuzumab's Clinical Effects

EGFR-targeting therapy as an evolving concept: learning from nimotuzumab clinical development.

Engineering the binding site of an antibody against N-glycolyl GM3: from functional mapping to novel anti-ganglioside specificities.

Gangliosides, Ab1 and Ab2 antibodies I. Towards a molecular dissection of an idiotype-anti-idiotype system

Gangliosides, Ab1 and Ab2 antibodies II. Light versus heavy chain: An idiotype-anti-idiotype case study.

Geometric and chemical patterns of interaction in protein--ligand complexes and their application in docking

Human IL-2 mutein with higher antitumor efficacy than wild type IL-2.

KBE009: An antimalarial bestatin-like inhibitor of the Plasmodium falciparum M1 aminopeptidase discovered in an Ugi multicomponent reaction-derived peptidomimetic library.

Light-chain shuffling results in successful phage display selection of functional prokaryotic-expressed antibody fragments to N-glycolyl GM3 ganglioside

Nimotuzumab and cetuximab block ligand-independent EGF receptor signaling efficiently at different concentrations.

Nimotuzumab, an antitumor antibody that targets the epidermal growth factor receptor, blocks ligand binding while permitting the active receptor conformation

Non-classical binding of a polyreactive α-type anti-idiotypic antibody to B cells.

Predicting the right spacing between protein immobilization sites on self-assembled monolayers to optimize ligand binding

Redefinition of the carbohydrate specificity of Erythrina corallodendron lectin based on solid-phase binding assays and molecular modeling of native and recombinant forms obtained by site-directed mutagenesis

Setting up a large set of protein-ligand PDB complexes for the development and validation of knowledge-based docking algorithms

Structure and molecular interactions of a unique antitumor antibody specific for N-glycolyl GM3

Structure of the Fab fragment of the anti-murine EGFR antibody 7A7 and exploration of its receptor binding site

Switching on cytotoxicity by a single mutation at the heavy chain variable region of an anti-ganglioside antibody ⬇️

The anti-CD6 antibody itolizumab provides clinical benefit without lymphopenia in rheumatoid arthritis patients: results from a 6-month, open-label Phase I clinical trial.

gmx_MMPBSA: A New Tool to Perform End-State Free Energy Calculations with GROMACS