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List of works by Jo Van Damme

"Reverse degradomics", monitoring of proteolytic trimming by multi-CE and confocal detection of fluorescent substrates and reaction products

scientific article published in July 2009

A monoclonal antibody inhibits gelatinase B/MMP-9 by selective binding to part of the catalytic domain and not to the fibronectin or zinc binding domains

scientific article published on 26 October 2006

Amine-reactive OVA multimers for auto-vaccination against cytokines and other mediators: perspectives illustrated for GCP-2 in L. major infection

scientific article

Angiostatic and chemotactic activities of the CXC chemokine CXCL4L1 (platelet factor-4 variant) are mediated by CXCR3.

scientific article

Angiostatic, tumor inflammatory and anti-tumor effects of CXCL4(47-70) and CXCL4L1(47-70) in an EGF-dependent breast cancer model

scientific article

Assays for chemotaxis.

scientific article published on January 2004

Bacterial lipopolysaccharide selectively up-regulates the function of the chemotactic peptide receptor formyl peptide receptor 2 in murine microglial cells.

scientific article

Basic chemokine-derived glycosaminoglycan binding peptides exert antiviral properties against dengue virus serotype 2, herpes simplex virus-1 and respiratory syncytial virus.

scientific article published on 6 November 2015

Biological activity of CXCL8 forms generated by alternative cleavage of the signal peptide or by aminopeptidase-mediated truncation.

scientific article

CC chemokine ligand-2 synergizes with the nonchemokine G protein-coupled receptor ligand fMLP in monocyte chemotaxis, and it cooperates with the TLR ligand LPS via induction of CXCL8.

scientific article published on 18 May 2009

CCR8-dependent activation of the RAS/MAPK pathway mediates anti-apoptotic activity of I-309/ CCL1 and vMIP-I.

scientific article published in February 2003

CD26/dipeptidylpeptidase IV-chemokine interactions: double-edged regulation of inflammation and tumor biology

scientific article

COOH-terminal SAA1 peptides fail to induce chemokines but synergize with CXCL8 and CCL3 to recruit leukocytes via FPR2.

scientific article

CXC chemokine expression profiles in aqueous humor of patients with different clinical entities of endogenous uveitis.

scientific article published on 7 April 2011

CXCL4L1 and CXCL4 signaling in human lymphatic and microvascular endothelial cells and activated lymphocytes: involvement of mitogen-activated protein (MAP) kinases, Src and p70S6 kinase.

scientific article published on 28 January 2014

CXCR3 determines strain susceptibility to murine cerebral malaria by mediating T lymphocyte migration toward IFN-gamma-induced chemokines

scientific article published in April 2008

CXCR3 ligands in disease and therapy.

scientific article

CXCR4 and CCR5 ligands cooperate in monocyte and lymphocyte migration and in inhibition of dual-tropic (R5/X4) HIV-1 infection

scientific article published on 7 March 2011

Capacity of wild-type and chemokine-armed parvovirus H-1PV for inhibiting neo-angiogenesis

scientific article published on 4 October 2013

Carboxyterminal cleavage of the chemokines MIG and IP-10 by gelatinase B and neutrophil collagenase

scientific article published on 01 October 2003

Carcinoma cell-derived chemokines and their presence in oral fluid.

scientific article published in August 2009

Chemoattractants and cytokines in primary ciliary dyskinesia and cystic fibrosis: key players in chronic respiratory diseases

scientific article published on 27 November 2017

Chemokine isoforms and processing in inflammation and immunity

scientific article

Chemokine-Induced Macrophage Polarization in Inflammatory Conditions

scientific article published on 07 September 2018

Chemokine/chemokine receptor nomenclature

scientific article (publication date: October 2002)

Chemokines and gelatinases in the aqueous humor of patients with active uveitis

scientific article published on 01 September 2004

Chemokines and other GPCR ligands synergize in receptor-mediated migration of monocyte-derived immature and mature dendritic cells.

scientific article

Chemokines in proliferative diabetic retinopathy and proliferative vitreoretinopathy

scientific article published in September 2006

Chemokines synergize in the recruitment of circulating neutrophils into inflamed tissue

scientific article published on 01 May 2005

Chemotactic activity of human blood leukocytes in plasma treated with EDTA: chemoattraction of neutrophils about monocytes is mediated by the generation of NAP-2.

scientific article published in July 2002

Circular trimers of gelatinase B/matrix metalloproteinase-9 constitute a distinct population of functional enzyme molecules differentially regulated by tissue inhibitor of metalloproteinases-1.

scientific article

Circulating bone-marrow-derived endothelial precursor cells contribute to neovascularization in diabetic epiretinal membranes

scientific article published on 01 May 2011

Citrullination and proteolytic processing of chemokines by Porphyromonas gingivalis.

scientific article

Citrullination of CXCL10 and CXCL11 by peptidylarginine deiminase: a naturally occurring posttranslational modification of chemokines and new dimension of immunoregulation

scientific article

Citrullination of CXCL12 differentially reduces CXCR4 and CXCR7 binding with loss of inflammatory and anti-HIV-1 activity via CXCR4.

scientific article

Citrullination of CXCL8 increases this chemokine's ability to mobilize neutrophils into the blood circulation.

scientific article published on 16 July 2009

Citrullination of TNF-α by peptidylarginine deiminases reduces its capacity to stimulate the production of inflammatory chemokines.

scientific article

Contribution of intracellular Ca2+ stores to Ca2+ signaling during chemokinesis of human neutrophil granulocytes.

scientific article

Cytokine profiles in aqueous humor of patients with different clinical entities of endogenous uveitis.

scientific article published on 31 January 2011

Detection and quantification of citrullinated chemokines

scientific article

Development by Genetic Immunization of Monovalent Antibodies (Nanobodies) Behaving as Antagonists of the Human ChemR23 Receptor

scientific article published on 10 February 2016

Differential CXC and CX3C Chemokine Expression Profiles in Aqueous Humor of Patients With Specific Endogenous Uveitic Entities

scientific article published on 01 May 2018

Differential recognition and scavenging of native and truncated macrophage-derived chemokine (macrophage-derived chemokine/CC chemokine ligand 22) by the D6 decoy receptor

scientific journal article

Differential regulation of chemokine production by Fcgamma receptor engagement in human monocytes: association of CCL1 with a distinct form of M2 monocyte activation (M2b, Type 2).

scientific article published on 30 May 2006

Effect of posttranslational processing on the in vitro and in vivo activity of chemokines.

scientific article published on 10 December 2010

Effector mechanisms of interleukin-17 in collagen-induced arthritis in the absence of interferon-gamma and counteraction by interferon-gamma.

scientific article published on 17 August 2009

Expression of angiostatic platelet factor-4var/CXCL4L1 counterbalances angiogenic impulses of vascular endothelial growth factor, interleukin-8/CXCL8, and stromal cell-derived factor 1/CXCL12 in esophageal and colorectal cancer.

scientific article published on 23 March 2010

Expression of interleukin (IL)-10 family cytokines in aqueous humour of patients with specific endogenous uveitic entities: elevated levels of IL-19 in human leucocyte antigen-B27-associated uveitis

scientific article published on 13 February 2019

Expression of stem cell factor/c-kit signaling pathway components in diabetic fibrovascular epiretinal membranes.

scientific article

Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation

scientific article (publication date: 11 July 2003)

GCP-2/CXCL6 synergizes with other endothelial cell-derived chemokines in neutrophil mobilization and is associated with angiogenesis in gastrointestinal tumors

scientific article published on 01 February 2005

Gelatinase B/MMP-9 and neutrophil collagenase/MMP-8 process the chemokines human GCP-2/CXCL6, ENA-78/CXCL5 and mouse GCP-2/LIX and modulate their physiological activities.

scientific article

Gelatinase B/matrix metalloproteinase-9 is a phase-specific effector molecule, independent from Fas, in experimental autoimmune encephalomyelitis

scientific article published in PLoS ONE

Glycosaminoglycans Regulate CXCR3 Ligands at Distinct Levels: Protection against Processing by Dipeptidyl Peptidase IV/CD26 and Interference with Receptor Signaling.

scientific article published on 13 July 2017

HIV-1 infection induces a type I IFN response in primary CD4+ T cells.

scientific article published on 19 September 2013

Identification and characterization of MIP-1α/CCL3 isoform 2 from bovine serum as a potent monocyte/dendritic cell chemoattractant.

scientific article published on 7 December 2012

Identification of Biologically Active Chemokine Isoforms from Ascitic Fluid and Elevated Levels of CCL18/Pulmonary and Activation-regulated Chemokine in Ovarian Carcinoma

scientific article published in Journal of Biological Chemistry

Immunomodulation as Rescue for Chronic Atonic Skin Wounds.

scientific article published on 27 February 2018

Immunopathology and Dexamethasone Therapy in a New Model for Malaria-associated Acute Respiratory Distress Syndrome

article

Immunopathology and dexamethasone therapy in a new model for malaria-associated acute respiratory distress syndrome.

scientific article

In vivo regulation of chemokine activity by post-translational modification.

scientific article published on 30 April 2013

Interference with glycosaminoglycan-chemokine interactions with a probe to alter leukocyte recruitment and inflammation in vivo.

scientific article

Interleukin-17 regulates chemokine and gelatinase B expression in fibroblasts to recruit both neutrophils and monocytes

scientific article published on 22 July 2009

Langerhans cell histiocytosis: a cytokine/chemokine-mediated disorder?

scientific article published on September 2011

Local Cytokine Expression Profiling in Patients with Specific Autoimmune Uveitic Entities

scientific article published on 04 June 2019

MCP-3 (CCL7) delivered by parvovirus MVMp reduces tumorigenicity of mouse melanoma cells through activation of T lymphocytes and NK cells

scientific article published in 2007

Macrophage inflammatory protein-1

scientific article (publication date: December 2002)

Matrix Metalloproteinase-9-Generated COOH-, but Not NH2-Terminal Fragments of Serum Amyloid A1 Retain Potentiating Activity in Neutrophil Migration to CXCL8, With Loss of Direct Chemotactic and Cytokine-Inducing Capacity.

scientific article

Microbial Toll-like receptor ligands differentially regulate CXCL10/IP-10 expression in fibroblasts and mononuclear leukocytes in synergy with IFN-γ and provide a mechanism for enhanced synovial chemokine levels in septic arthritis

scientific article published on 01 November 2003

Microbiomic and Posttranslational Modifications as Preludes to Autoimmune Diseases

scientific article

Myeloid cells are tunable by a polyanionic polysaccharide derivative and co-determine host rescue from lethal virus infection.

scientific article published on 13 August 2010

Myofibroblasts in proliferative diabetic retinopathy can originate from infiltrating fibrocytes and through endothelial-to-mesenchymal transition (EndoMT)

scientific article published on 28 January 2015

Natural nitration of CXCL12 reduces its signaling capacity and chemotactic activity in vitro and abrogates intra-articular lymphocyte recruitment in vivo.

scientific article published on 23 August 2016

Neutrophils from Patients with Primary Ciliary Dyskinesia Display Reduced Chemotaxis to CXCR2 Ligands.

scientific article published on 22 September 2017

Obligatory involvement of CD26/dipeptidyl peptidase IV in the activation of the antiretroviral tripeptide glycylprolylglycinamide (GPG-NH(2)).

scientific article

On the structure and functions of gelatinase B/matrix metalloproteinase-9 in neuroinflammation.

scientific article

Overview of the mechanisms regulating chemokine activity and availability.

scientific article published on July 2012

PF-4var/CXCL4L1 predicts outcome in stable coronary artery disease patients with preserved left ventricular function

scientific article

Platelet factor-4 variant chemokine CXCL4L1 inhibits melanoma and lung carcinoma growth and metastasis by preventing angiogenesis.

scientific article

Platelets release CXCL4L1, a nonallelic variant of the chemokine platelet factor-4/CXCL4 and potent inhibitor of angiogenesis.

scientific article published on 30 September 2004

Posttranslational modification of the NH2-terminal region of CXCL5 by proteases or peptidylarginine Deiminases (PAD) differently affects its biological activity

scientific article

Posttranslational processing of chemokines

scientific article published on 01 January 2004

Probing cytokines, chemokines and matrix metalloproteinases towards better immunotherapies of multiple sclerosis.

scientific article published on October 2011

Protective role of IFN-gamma in collagen-induced arthritis conferred by inhibition of mycobacteria-induced granulocyte chemotactic protein-2 production.

scientific article published on 2 January 2007

Proteolytic processing of CXCL11 by CD13/aminopeptidase N impairs CXCR3 and CXCR7 binding and signaling and reduces lymphocyte and endothelial cell migration

scientific article

Purification, identification, and synthesis of chemokines.

scientific article

Rabbit neutrophil chemotactic protein (NCP) activates both CXCR1 and CXCR2 and is the functional homologue for human CXCL6.

scientific article published in November 2004

Recombinant Parvoviruses Armed to Deliver CXCL4L1 and CXCL10 Are Impaired in Their Antiangiogenic and Antitumoral Effects in a Kaposi Sarcoma Tumor Model Due To the Chemokines' Interference with the Virus Cycle

scientific article published on 2 January 2017

Regulation of Chemokine Activity - A Focus on the Role of Dipeptidyl Peptidase IV/CD26

scientific article

Regulation of TNF-α with a focus on rheumatoid arthritis

scientific article published on 30 April 2013

Regulation of the immune response by the interaction of chemokines and proteases

scientific article (publication date: 2003)

Relative distribution and biological characterization of CXCL4L1 isoforms in platelets from healthy donors.

scientific article published on 28 August 2017

Remnant epitopes, autoimmunity and glycosylation.

scientific article

Role of the autocrine chemokines MIP-1alpha and MIP-1beta in the metastatic behavior of murine T cell lymphoma.

scientific article published on October 2002

Serum amyloid A chemoattracts immature dendritic cells and indirectly provokes monocyte chemotaxis by induction of cooperating CC and CXC chemokines.

scientific article

Serum amyloid A1α induces paracrine IL-8/CXCL8 via TLR2 and directly synergizes with this chemokine via CXCR2 and formyl peptide receptor 2 to recruit neutrophils

scientific article published on 21 August 2015

Structure and Expression of Different Serum Amyloid A (SAA) Variants and their Concentration-Dependent Functions During Host Insults

scientific article

Synergistic induction of CXCL9 and CXCL11 by Toll-like receptor ligands and interferon-gamma in fibroblasts correlates with elevated levels of CXCR3 ligands in septic arthritis synovial fluids.

scientific article published on 2 March 2004

Synergistic up-regulation of MCP-2/CCL8 activity is counteracted by chemokine cleavage, limiting its inflammatory and anti-tumoral effects

scientific article (publication date: March 2009)

Synergy between coproduced CC and CXC chemokines in monocyte chemotaxis through receptor-mediated events.

scientific article

Synergy in cytokine and chemokine networks amplifies the inflammatory response.

scientific article

The CC chemokine CCL20 and its receptor CCR6.

scientific article

The CC chemokines CCL8, CCL13 and CCL20 are local inflammatory biomarkers of HLA-B27-associated uveitis

scientific article published on 21 September 2018

The COOH-terminal peptide of platelet factor-4 variant (CXCL4L1/PF-4var47-70) strongly inhibits angiogenesis and suppresses B16 melanoma growth in vivo.

scientific article published on 9 March 2010

The Chemokine Platelet Factor-4 Variant (PF-4var)/CXCL4L1 Inhibits Diabetes-Induced Blood-Retinal Barrier Breakdown

scientific article

The Cytokine Interleukin-6 and the Chemokines CCL20 and CXCL13 Are Novel Biomarkers of Specific Endogenous Uveitic Entities.

scientific article published in September 2016

The Positively Charged COOH-terminal Glycosaminoglycan-binding CXCL9(74-103) Peptide Inhibits CXCL8-induced Neutrophil Extravasation and Monosodium Urate Crystal-induced Gout in Mice.

scientific article

The activated form of gelatinase B/matrix metalloproteinase-9 is associated with diabetic vitreous hemorrhage

scientific article published on 27 April 2006

The countercurrent principle in invasion and metastasis of cancer cells. Recent insights on the roles of chemokines.

scientific article published in January 2004

The cytokine-serum amyloid A-chemokine network

scientific article

The expression and role of CXC chemokines in colorectal cancer.

scientific article published on 14 October 2011

The role of CXC chemokines and their receptors in cancer.

scientific article published on 24 June 2008

The role of CXC chemokines in the transition of chronic inflammation to esophageal and gastric cancer.

scientific article

The role of the CXC chemokines platelet factor-4 (CXCL4/PF-4) and its variant (CXCL4L1/PF-4var) in inflammation, angiogenesis and cancer

scientific article

The unique property of the CC chemokine regakine-1 to synergize with other plasma-derived inflammatory mediators in neutrophil chemotaxis does not reside in its NH2-terminal structure.

scientific article

Tonic inhibition of chemotaxis in human plasma

scientific article

Truncation of CXCL12 by CD26 reduces its CXC chemokine receptor 4- and atypical chemokine receptor 3-dependent activity on endothelial cells and lymphocytes

scientific article published on 16 March 2017

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