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List of works by José E. Piñero

A Fluorometric Assay for the <i>In Vitro</i> Evaluation of Activity against Naegleria fowleri Cysts

scientific article published on 31 August 2022

A multisystemic Acanthamoeba infection in a dog in Tenerife, Canary Islands, Spain

scientific article published on 26 August 2014

Acanthamoeba belonging to T3, T4, and T11: genotypes isolated from air-conditioning units in Santiago, Chile

scientific article

Acanthamoeba genotypes T2, T4, and T11 in soil sources from El Hierro island, Canary Islands, Spain.

scientific article

Acanthamoeba keratitis: an emerging disease gathering importance worldwide?

scientific article published on 21 February 2013

Acanthamoeba spp.: efficacy of Bioclen FR One Step, a povidone-iodine based system for the disinfection of contact lenses.

scientific article

Acanthamoeba spp.: in vitro effects of clinical isolates on murine macrophages, osteosarcoma and HeLa cells.

scientific article

Activity assessment of Tunisian olive leaf extracts against the trophozoite stage of Acanthamoeba

scientific article published on 17 May 2013

Activity of olive leaf extracts against the promastigote stage of Leishmania species and their correlation with the antioxidant activity.

scientific article published on 21 March 2014

Ammoides pusilla (Apiaceae) essential oil: Activity against Acanthamoeba castellanii Neff.

scientific article

Amoebicidal Activity of Caffeine and Maslinic Acid by the Induction of Programmed Cell Death in Acanthamoeba

scientific article

Amoebicidal Effect of COVID Box Molecules against Acanthamoeba: A Study of Cell Death

scientific article published on 20 June 2024

Amoebicidal activity of α-bisabolol, the main sesquiterpene in chamomile (Matricaria recutita L.) essential oil against the trophozoite stage of Acanthamoeba castellani Neff.

scientific article

Amoebicidal effect of synthetic indoles against <i>Acanthamoeba</i> spp.: a study of cell death

scientific article published on 3 April 2024

Amoebicidal, antimicrobial and in vitro ROS scavenging activities of Tunisian Rubus ulmifolius Schott, methanolic extract

scientific article

Analysis of NLS and rRNA binding motifs in the L25 ribosomal protein from Leishmania (viannia) braziliensis: investigation of its diagnostic capabilities.

scientific article

Anti- Activity of Brominated Sesquiterpenes from ⬇️

scientific article published on 11 November 2018

Anti-Acanthamoeba activity of Tunisian Thymus capitatus essential oil and organic extracts.

scientific article

Anti-COVID Drugs (MMV COVID Box) as Leishmanicidal Agents: Unveiling New Therapeutic Horizons

scientific article published on 20 February 2024

Antiamoebic Activities of Indolocarbazole Metabolites Isolated from Streptomyces sanyensis Cultures ⬇️

scientific article published on 17 October 2019

Antiamoeboid activity of squamins C-F, cyclooctapeptides from Annona globifora

scientific article published on 11 August 2021

Antikinetoplastid Activity of Indolocarbazoles from Streptomyces sanyensis

scientific article published on 24 April 2020

Antikinetoplastid Activity of Sesquiterpenes Isolated from the Zoanthid Palythoa aff. clavata

scientific article published in 2021

Antileishmanial activities of dihydrochalcones from piper elongatum and synthetic related compounds. Structural requirements for activity.

scientific article published in September 2003

Antioxidant and Leishmanicidal Evaluation of Pulicaria Inuloides Root Extracts: A Bioguided Fractionation

scientific article published on 23 October 2019

Antiprotozoal activities of marine polyether triterpenoids

scientific article published on 11 September 2019

Antiprotozoan lead discovery by aligning dry and wet screening: prediction, synthesis, and biological assay of novel quinoxalinones.

scientific article

Apoptosis-like cell death upon kinetoplastid induction by compounds isolated from the brown algae Dictyota spiralis

scientific article published on 12 April 2021

Apoptotic protein profile in Leishmania donovani after treatment with hexaazatrinaphthylenes derivatives

scientific article

Assessment of the antiprotozoal activity of Pulicaria inuloides extracts, an Algerian medicinal plant: leishmanicidal bioguided fractionation.

scientific article published on 6 January 2018

Balamuthia mandrillaris in South America: an emerging potential hidden pathogen in Perú.

scientific article published on 21 May 2014

Balamuthia mandrillaris therapeutic mud bath in Jamaica.

scientific article published on 22 October 2014

Bioassay guided isolation and identification of anti-Acanthamoeba compounds from Tunisian olive leaf extracts.

scientific article published on 12 April 2014

Chamigrane-Type Sesquiterpenes from Laurencia dendroidea as Lead Compounds against Naegleria fowleri ⬇️

scientific article published on 31 March 2023

Chemical composition and anti-Acanthamoeba activity of Melaleuca styphelioides essential oil.

scientific article published on 2 November 2017

Co-isolation of Vahlkampfia and acanthamoeba in acanthamoeba-like keratitis in a Spanish population.

scientific article published on May 2013

Combined Amoebicidal Effect of Atorvastatin and Commercial Eye Drops against Acanthamoeba castellanii Neff: In Vitro Assay Based on Mixture Design

scientific article published on 17 March 2020

Combined effect of carnosol, rosmarinic acid and thymol on the oxidative stability of soybean oil using a simplex centroid mixture design

scientific article

Correlation of radical-scavenging capacity and amoebicidal activity of Matricaria recutita L. (Asteraceae).

scientific article published on 14 September 2017

Design, synthesis and evaluation of amino-substituted 1H-phenalen-1-ones as anti-leishmanial agents

scientific article published on 14 October 2017

Detection and molecular characterization of Acanthamoeba spp. in stray cats from Madrid, Spain.

scientific article published in March 2018

Detection of Acanthamoeba on the ocular surface in a Spanish population using the Schirmer strip test: pathogenic potential, molecular classification and evaluation of the sensitivity to chlorhexidine and voriconazole of the isolated Acanthamoeba st

scientific article published on August 2015

Development of a rapid polymerase chain reaction-ELISA assay using polystyrene beads for the detection of Toxoplasma gondii DNA

scientific article published on 01 January 2003

Discovery of Amoebicidal Compounds by Combining Computational and Experimental Approaches

scientific article published on 23 November 2020

Effects of Ozone Treatment on Personal Protective Equipment Contaminated with SARS-CoV-2

scientific article published on 03 December 2020

Emerging Parasitic Protozoa ⬇️

scientific article published on 27 August 2020

Endosymbiotic Mycobacterium chelonae in a Vermamoeba vermiformis strain isolated from the nasal mucosa of an HIV patient in Lima, Peru

scientific article published on March 2014

Evaluation of Acanthamoeba myosin-IC as a potential therapeutic target

scientific article

Evaluation of Indolocarbazoles from Streptomyces sanyensis as a Novel Source of Therapeutic Agents against the Brain-Eating Amoeba Naegleria fowleri

scientific article published on 25 May 2020

Evaluation of Oxasqualenoids from the Red Alga Laurencia viridis against Acanthamoeba

scientific article published on 19 July 2019

Evaluation of the anti-Acanthamoeba activity of two commercial eye drops commonly used to lower eye pressure.

scientific article published on August 2017

Evaluation of the sensitivity to chlorhexidine, voriconazole and itraconazole of T4 genotype Acanthamoeba isolated from Mexico

scientific article published on 12 January 2019

Exploring therapeutic approaches against Naegleria fowleri infections through the COVID box

scientific article published in August 2024

First Report of Acanthamoeba Genotype T4 from the Newly Formed Tajogaite Volcano Tephra (La Palma, Canary Islands)

scientific article published on 27 July 2024

Fungus-elicited metabolites from plants as an enriched source for new leishmanicidal agents: antifungal phenyl-phenalenone phytoalexins from the banana plant (Musa acuminata) target mitochondria of Leishmania donovani promastigotes

scientific article published on May 2004

Genotyping of clinical isolates of Acanthamoeba genus in Venezuela.

scientific article

Genotyping of potentially pathogenic Acanthamoeba strains isolated from nasal swabs of healthy individuals in Peru

scientific article published on 17 October 2013

Global Health Priority Box: Discovering Flucofuron as a Promising Antikinetoplastid Compound

scientific article published on 25 April 2024

High occurrence of Acanthamoeba genotype T4 in soil sources from Bolívar State, Venezuela.

scientific article

In Vitro Activity of Statins against Naegleria fowleri

scientific article published on 08 August 2019

In Vitro Evaluation of Combined Commercialized Ophthalmic Solutions Against Acanthamoeba Strains

scientific article published on 25 July 2019

In vitro activities of hexaazatrinaphthylenes against Leishmania spp

scientific article published on 9 March 2015

In vitro activity of perifosine: a novel alkylphospholipid against the promastigote stage of Leishmania species

article

In vitro amoebicidal effects of arabinogalactan-based ophthalmic solution

scientific article published on 20 April 2021

In vitro effects of triterpenic acids from olive leaf extracts on the mitochondrial membrane potential of promastigote stage of Leishmania spp.

scientific article published on 17 September 2014

In vitro validation of the amoebicidal activity of commercial eye drops as second activity

scientific article published on 04 March 2021

Induction of Programmed Cell Death in Acanthamoeba culbertsoni by the Repurposed Compound Nitroxoline

scientific article published on 6 December 2023

Inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and application of statins as a novel effective therapeutic approach against Acanthamoeba infections

scientific article published on 31 October 2012

In vitro activity of 1H-phenalen-1-one derivatives against Acanthamoeba castellanii Neff and their mechanisms of cell death

scientific article published on 12 September 2017

In vitro amoebicidal and antioxidant activities of some Tunisian seaweeds

scientific article

In vitro interactions of Acanthamoeba castellanii Neff and Vibrio harveyi

scientific article published on 13 September 2017

Is Balamuthia mandrillaris a public health concern worldwide?

scientific article published on 26 August 2013

Isolation and Molecular Identification of Naegleria australiensis in Irrigation Water of Fuerteventura Island, Spain

scientific article published on 02 April 2019

Isolation and Molecular Identification of Vermamoeba vermiformis Strains from Soil Sources in El Hierro Island, Canary Islands, Spain.

scientific article

Isolation and characterization of Acanthamoeba strains from soil samples in Gran Canaria, Canary Islands, Spain.

scientific article

Isolation and genotyping of acanthamoeba strains from soil sources from Jamaica, West Indies

scientific article published on 10 December 2014

Isolation and molecular characterization of Acanthamoeba and Balamuthia mandrillaris from combination shower units in Costa Rica.

scientific article published on 19 August 2014

Isolation and molecular characterization of Acanthamoeba genotypes in recreational and domestic water sources from Jamaica, West Indies

scientific article published on September 2015

Isolation and molecular characterization of a Naegleria strain from a recreational water fountain in Tenerife, Canary Islands, Spain

scientific article published on June 2017

Isolation and molecular identification of free-living amoebae from dishcloths in Tenerife, Canary Islands, Spain

scientific article published on 01 February 2019

Isolation of thermotolerant Vermamoeba vermiformis strains from water sources in Lanzarote Island, Canary Islands, Spain.

scientific article

Leishmanicidal Constituents from the Leaves of Piper rusbyi

Leishmanicidal activity of α-bisabolol from Tunisian chamomile essential oil

scientific article published on 28 June 2018

Leishmanicidal and Reversal Multidrug Resistance Constituents fromAeonium lindleyi

scientific article published on 21 July 2010

Marine Meroterpenoids Isolated from Gongolaria abies-marina Induce Programmed Cell Death in Naegleria fowleri

scientific article published on 17 July 2023

Molecular characterization of Acanthamoeba strains isolated from domestic dogs in Tenerife, Canary Islands, Spain

scientific article published on 26 February 2015

Naegleria fowleri

scientific article published on 09 July 2019

Natural infection of Lutzomyia neivai with Leishmania spp. in northwestern Argentina.

scientific article published on 10 March 2006

New administration model of trans-chalcone biodegradable polymers for the treatment of experimental leishmaniasis.

scientific article published on 9 March 2006

PCR-ELISA for diagnosis of mucocutaneous leishmaniasis

scientific article published on 01 May 1999

Parasitic helminths of the wild rabbit, Oryctolagus cuniculus, in different bioclimatic zones in Tenerife, Canary Islands

scientific article published on 01 December 2003

Perifosine Mechanisms of Action in Leishmania Species.

scientific article published on 17 January 2017

Presence of Acanthamoeba in the ocular surface in a Spanish population of contact lens wearers.

scientific article published in June 2018

Presence of potentially pathogenic free-living amoebae strains from well water samples in Guinea-Bissau

scientific article published on 17 June 2014

PrestoBlue® and AlamarBlue® are equally useful as agents to determine the viability of Acanthamoeba trophozoites.

scientific article

Programmed cell death in Acanthamoeba castellanii Neff induced by several molecules present in olive leaf extracts.

scientific article published on 31 August 2017

RAPD method useful for distinguishing Leishmania species: design of specific primers for L. braziliensis.

scientific article

Repurposing of Nitroxoline as an Alternative Primary Amoebic Meningoencephalitis Treatment

scientific article published on 3 August 2023

Salvadoran Celastraceae Species as a Source of Antikinetoplastid Quinonemethide Triterpenoids

scientific article published on 25 January 2024

Screening of the pathogen box for the identification of anti-Acanthamoeba agents

scientific article published on 04 May 2019

Spiralyde A, an Antikinetoplastid Dolabellane from the Brown Alga

scientific article published on 25 March 2019

Statins and voriconazole induce programmed cell death in Acanthamoeba castellanii

scientific article

Staurosporine from Streptomyces sanyensis activates Programmed Cell Death in Acanthamoeba via the mitochondrial pathway and presents low in vitro cytotoxicity levels in a macrophage cell line ⬇️

scientific article published on 12 August 2019

Structure elucidation, total assignment of the 1 H and 13 C chemical shifts, and absolute configuration by NMR techniques of dammarane-type triterpenes from Hippocratea volubilis

scientific article published on 14 August 2017

Successful Monitoring and Treatment of Intraocular Dissemination of Acanthamoeba

scientific article published on 01 November 2012

Synthesis and in vitro antiprotozoal evaluation of substituted phenalenone analogues.

scientific article

The isolation of Balamuthia mandrillaris from environmental sources from Peru.

scientific article published on 30 April 2014

The potential pathogenicity of chlorhexidine-sensitive Acanthamoeba strains isolated from contact lens cases from asymptomatic individuals in Tenerife, Canary Islands, Spain

scientific article

The therapeutic potential of novel isobenzofuranones against Naegleria fowleri

scientific article published on 02 October 2021

Toxic effects of selected proprietary dry eye drops on Acanthamoeba.

scientific article published on 4 June 2018

Ursolic Acid Derivatives as Potential Agents Against Acanthamoeba Spp

scientific article published on 23 August 2019

Validation of a rapid method for extraction of total RNA applied to Leishmania promastigotes

scientific article published on 01 August 1999

Variation in Campylobacter jejuni culturability in presence of Acanthamoeba castellanii Neff

scientific article

Voriconazole as a first-line treatment against potentially pathogenic Acanthamoeba strains from Peru

scientific article published on 22 November 2013

Withanolides from Withania aristata as Antikinetoplastid Agents through Induction of Programmed Cell Death

scientific article published on 01 October 2019

[Detection by nested-PCR of Toxoplasma gondii in patients infected with human immunodeficiency virus]

scientific article published on 01 March 2002

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