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List of works by Michael D Onken

A surprising cross-species conservation in the genomic landscape of mouse and human oral cancer identifies a transcriptional signature predicting metastatic disease.

scientific article published on 25 March 2014

Association between gene expression profile, proliferation and metastasis in uveal melanoma

scientific article published on September 2010

Association between microarray gene expression signature and extravascular matrix patterns in primary uveal melanomas

scientific article published on 01 October 2005

Chloroquine sensitizes GNAQ/11-mutated melanoma to MEK1/2 inhibition

scientific article published on 15 September 2020

Collaborative Ocular Oncology Group report number 1: prospective validation of a multi-gene prognostic assay in uveal melanoma

scientific article

Endothelial monolayers and transendothelial migration depend on mechanical properties of the substrate

scientific article published on December 2014

Frequent mutation of BAP1 in metastasizing uveal melanomas

scientific article

Functional gene expression analysis uncovers phenotypic switch in aggressive uveal melanomas.

scientific article

Gene Expressing Profiling of Iris Melanomas ⬇️

scientific article published on January 1, 2013

Gene expression profiling in uveal melanoma reveals two molecular classes and predicts metastatic death

scientific article

Genomic analysis to define molecular basis of aggressiveness in a mouse model of oral cancer

scientific article

Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma

scientific article

Impaired cholesterol efflux in senescent macrophages promotes age-related macular degeneration

scientific article

L-Plastin promotes podosome longevity and supports macrophage motility

scientific article published on 7 September 2016

Loss of heterozygosity of chromosome 3 detected with single nucleotide polymorphisms is superior to monosomy 3 for predicting metastasis in uveal melanoma

scientific article published on 15 May 2007

Metastatic model of HPV+ oropharyngeal squamous cell carcinoma demonstrates heterogeneity in tumor metastasis.

scientific article published on 22 March 2016

Micro-RNAs associated with metastasis in uveal melanoma identified by multiplexed microarray profiling.

scientific article

Oncogenic mutations in GNAQ occur early in uveal melanoma

scientific article

Prognostic biomarkers in uveal melanoma: evidence for a stem cell-like phenotype associated with metastasis

scientific article published on 01 June 2008

Recurrent mutations at codon 625 of the splicing factor SF3B1 in uveal melanoma.

scientific article published on 13 January 2013

Targeting nucleotide exchange to inhibit constitutively active G protein α subunits in cancer cells

scientific article published on 04 September 2018

Targeting primary and metastatic uveal melanoma with a G protein inhibitor

scientific article published on 01 January 2021

Technical Advance: New in vitro method for assaying the migration of primary B cells using an endothelial monolayer as substrate

scientific article published on 21 June 2017

The secreted kinase ROP17 promotes Toxoplasma gondii dissemination by hijacking monocyte tissue migration

scientific article published on 22 July 2019

Transcriptomic versus chromosomal prognostic markers and clinical outcome in uveal melanoma

scientific article

Transposase mapping identifies the genomic targets of BAP1 in uveal melanoma

scientific article published on 6 November 2018

Trojan Horse Transit Contributes to Blood-Brain Barrier Crossing of a Eukaryotic Pathogen.

scientific article published on 31 January 2017

Uveal melanoma cells utilize a novel route for transendothelial migration

scientific article (publication date: 2014)

p38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb-Hdm2 interaction and apoptosis

scientific article

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