List of works by Kelly Chibale

2,4-Diaminothienopyrimidines as orally active antimalarial agents

scientific article published on 28 January 2014

2-Aminopyrimidine based 4-aminoquinoline anti-plasmodial agents. Synthesis, biological activity, structure-activity relationship and mode of action studies

scientific article

3,5-Diaryl-2-aminopyridines as a novel class of orally active antimalarials demonstrating single dose cure in mice and clinical candidate potential

scientific article

A Novel Pyrazolopyridine with in Vivo Activity in Plasmodium berghei- and Plasmodium falciparum-Infected Mouse Models from Structure-Activity Relationship Studies around the Core of Recently Identified Antimalarial Imidazopyridazines

scientific article published on 26 October 2015

A Pharmacokinetic Study of Antimalarial 3,5-Diaryl-2-aminopyridine Derivatives

scientific article

A chemical approach towards understanding the mechanism and reversal of drug resistance in Plasmodium falciparum: is it viable?

scientific article published on April 2002

A new approach for anthelmintic discovery for humans

scientific article

Alternative solid-state forms of a potent antimalarial aminopyridine: X-ray crystallographic, thermal and solubility aspects

Aminopyrazolo[1,5-a]pyrimidines as potential inhibitors of Mycobacterium tuberculosis: Structure activity relationships and ADME characterization

scientific article published on 22 October 2015

Anticancer properties of distinct antimalarial drug classes

scientific article (publication date: 2013)

Antimalarial aminothiazoles and aminopyridines from phenotypic whole-cell screening of a SoftFocus(®) library

scientific article

Antimalarial benzoheterocyclic 4-aminoquinolines: Structure-activity relationship, in vivo evaluation, mechanistic and bioactivation studies

scientific article

Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase.

scientific article

Antimalarial pyrido[1,2-a]benzimidazoles

scientific article published on 16 June 2011

Antimicrobial activity of organometallic isonicotinyl and pyrazinyl ferrocenyl-derived complexes

scientific article published on 17 July 2017

Antiplasmodial activity, in vivo pharmacokinetics and anti-malarial efficacy evaluation of hydroxypyridinone hybrids in a mouse model

scientific article

Antiplasmodial and antitumor activity of dihydroartemisinin analogs derived via the aza-Michael addition reaction

scientific article published on 30 March 2011

Antiplasmodial and cytotoxicity evaluation of 3-functionalized 2-azetidinone derivatives

scientific article published on 12 June 2011

Antiplasmodial drug targets: a patent review (2000 - 2013).

scientific article

Antiplasmodial hirsutinolides from Vernonia staehelinoides and their utilization towards a simplified pharmacophore ⬇️

scientific article published on 3 April 2007

Antiplasmodial, beta-haematin inhibition, antitrypanosomal and cytotoxic activity in vitro of novel 4-aminoquinoline 2-imidazolines

scientific article

Antischistosomal Activity of Pyrido[1,2-a]benzimidazole Derivatives and Correlation with Inhibition of β-Hematin Formation

scientific article published on 25 April 2017

Application of combinatorial and parallel synthesis chemistry methodologies to antiparasitic drug discovery

scientific article

Application of multi-component reactions to antimalarial drug discovery. Part 1: Parallel synthesis and antiplasmodial activity of new 4-aminoquinoline Ugi adducts

scientific article published on August 2004

Application of multicomponent reactions to antimalarial drug discovery. Part 2: New antiplasmodial and antitrypanosomal 4-aminoquinoline gamma- and delta-lactams via a 'catch and release' protocol

scientific article published on 11 May 2006

Application of multicomponent reactions to antimalarial drug discovery. Part 3: discovery of aminoxazole 4-aminoquinolines with potent antiplasmodial activity in vitro

scientific article published on 27 June 2007

Artemisinin derivatives: a patent review (2006 - present).

scientific article published on 13 September 2012

Arylpiperazines displaying preferential potency against chloroquine-resistant strains of the malaria parasite Plasmodium falciparum

scientific article published on 18 November 2005

Benzoheterocyclic amodiaquine analogues with potent antiplasmodial activity: synthesis and pharmacological evaluation

scientific article

Bioisosteric ferrocenyl-containing quinolines with antiplasmodial and antitrichomonal properties

scientific article

Biotransformation and biocatalysis: roles and applications in the discovery of antimalarials

scientific article published on December 2012

CRIMALDDI: a co-ordinated, rational, and integrated effort to set logical priorities in anti-malarial drug discovery initiatives

scientific article

CRIMALDDI: platform technologies and novel anti-malarial drug targets

scientific article

Carbon-14 radiolabeling and tissue distribution evaluation of MMV390048.

scientific article

Cell-based medicinal chemistry optimization of high throughput screening hits for orally active antimalarials. Part 2: hits from SoftFocus kinase and other libraries

scientific article

Characterisation of artemisinin-chloroquinoline hybrids for potential metabolic liabilities

scientific article published on 4 September 2015

Chloroquine resistance: proposed mechanisms and countermeasures

scientific article published on October 2010

Chloroquine-containing compounds: a patent review (2010 - 2014).

scientific article published on 26 May 2015

Comparison of electrospray ionisation, atmospheric pressure chemical ionisation and atmospheric pressure photoionisation for the identification of metabolites from labile artemisinin-based anti-malarial drugs using a QTRAP® mass spectrometer

scientific article

Comparison of the antiplasmodial and falcipain-2 inhibitory activity of beta-amino alcohol thiolactone-chalcone and isatin-chalcone hybrids

scientific article

Computer-Aided Drug Discovery Approaches against the Tropical Infectious Diseases Malaria, Tuberculosis, Trypanosomiasis, and Leishmaniasis

scientific article published on 16 November 2015

Correction: Recent updates in the discovery and development of novel antimalarial drug candidates

article

Corrigendum to “Aminopyrazolo[1,5-a]pyrimidines as potential inhibitors of Mycobacterium tuberculosis: Structure activity relationships and ADME characterization” [Bioorg. Med. Chem. 23 (2015) 7240–7250]

scholarly article by Candice Soares de Melo et al published January 2016 in Bioorganic & Medicinal Chemistry

Corrigendum to “Synthesis and in vitro antitubercular activity of ferrocene-based hydrazones” [Bioorg. Med. Chem. Lett. 21 (2011) 2866–2868]

scholarly article by Aman Mahajan et al published June 2011 in Bioorganic & Medicinal Chemistry Letters

Crystallisation of an Unexpected Trinuclear Heteronuclear Carbosilane Congener of Ferroquine

Current and Future Strategies for Improving Drug Discovery Efficiency

Cycloaddition and one-carbon homologation studies in the synthesis of advanced iridoid precursors

scientific article published on 8 July 2009

Cyclometallated Pd(II) thiosemicarbazone complexes: new catalyst precursors for Suzuki-coupling reactions

Cyclopalladated complexes containing tridentate thiosemicarbazone ligands of biological significance: Synthesis, structure and antimalarial activity

Cyclopalladated organosilane-tethered thiosemicarbazones: novel strategies for improving antiplasmodial activity

scientific article published on 25 February 2016

Design, Synthesis, and Antiplasmodial Activity of Hybrid Compounds Based on (2R,3S)-N-Benzoyl-3-phenylisoserine

scientific article

Design, Synthesis, and Evaluation of Novel Hybrid Efflux Pump Inhibitors for Use against Mycobacterium tuberculosis

scientific article

Design, synthesis and anti-plasmodial evaluation in vitro of new 4-aminoquinoline isatin derivatives

scientific article published on May 2005

Design, synthesis and in vitro antimalarial evaluation of triazole-linked chalcone and dienone hybrid compounds

scientific article published on October 31, 2010

Design, synthesis, and In vitro antituberculosis activity of 2(5H)-Furanone derivatives

scientific article

Design, synthesis, and antimalarial activity of structural chimeras of thiosemicarbazone and ferroquine analogues

scientific article published on 5 October 2007

Designed Hybrid Compounds for Tropical Parasitic Diseases

Di- and Trinuclear Ruthenium-, Rhodium-, and Iridium-Functionalized Pyridyl Aromatic Ethers: A New Class of Antiparasitic Agents

scholarly article by Prinessa Chellan et al published 22 August 2013 in Organometallics

Drug metabolite generation using a laboratory evolved NADPH independent cytochrome P450: application of in vitro and in silico approaches

scientific article published on March 2013

Drug repositioning in the treatment of malaria and TB.

scientific article published on September 2011

Dual-acting diamine antiplasmodial and chloroquine resistance modulating agents

scientific article published on 25 April 2006

Effects of a domain-selective ACE inhibitor in a mouse model of chronic angiotensin II-dependent hypertension

scientific article published on July 2014

Effects of highly active novel artemisinin-chloroquinoline hybrid compounds on β-hematin formation, parasite morphology and endocytosis in Plasmodium falciparum

scientific article published on 8 May 2011

Enone- and chalcone-chloroquinoline hybrid analogues: in silico guided design, synthesis, antiplasmodial activity, in vitro metabolism, and mechanistic studies

scientific article

Esterase phenotyping in human liver in vitro: specificity of carboxylesterase inhibitors

scientific article

Evaluation of Ferrocenyl-Containing Benzothiazoles as Potential Antiplasmodial Agents

Exploiting a basic chemosensitizing pharmacophore hypothesis. Part 1: synthesis and biological evaluation of novel arylbromide and bicyclic chemosensitizers against drug-resistant malaria parasites

scientific article published on June 2005

Exploring the Versatility of Cycloplatinated Thiosemicarbazones as Antitumor and Antiparasitic Agents

Exploring the potential of xanthene derivatives as trypanothione reductase inhibitors and chloroquine potentiating agents

Extracting molecular information from African natural products to facilitate unique African-led drug-discovery efforts

scientific article published in March 2011

Facile transformation of Biginelli pyrimidin-2(1H)-ones to pyrimidines. In vitro evaluation as inhibitors of Mycobacterium tuberculosis and modulators of cytostatic activity

scientific article published on 15 March 2011

Fast in vitro methods to determine the speed of action and the stage-specificity of anti-malarials in Plasmodium falciparum

scientific article

Ferrocene-pyrimidine conjugates: Synthesis, electrochemistry, physicochemical properties and antiplasmodial activities

scientific article published on 30 May 2015

Ferrocenylthiosemicarbazones conjugated to a poly(propyleneimine) dendrimer scaffold: Synthesis and in vitro antimalarial activity

Five Solid Forms of a Potent Imidazopyridazine Antimalarial Drug Lead: A Preformulation Study

Gold(I) derived thiosemicarbazone complexes with rare halogen-halogen interaction-reduction of [Au(damp-C1,N)Cl2].

scientific article published on 29 January 2010

Heterobimetallic ferrocenylthiosemicarbazone palladium(II) complexes: Synthesis, electrochemistry and antiplasmodial evaluation

article by Muneebah Adams et al published September 2013 in Journal of Organometallic Chemistry

How can natural products serve as a viable source of lead compounds for the development of new/novel anti-malarials?

scientific article published on 15 March 2011

Identification and characterization of reactive metabolites in natural products-driven drug discovery

scientific article published on February 2012

Identification of Fast-Acting 2,6-Disubstituted Imidazopyridines That Are Efficacious in the in Vivo Humanized Plasmodium falciparum NODscidIL2Rγ null Mouse Model of Malaria.

scientific article published on 17 April 2018

Identification of New Human Malaria Parasite Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors by Pharmacophore and Structure-Based Virtual Screening

scientific article published on 25 February 2016

Identification of a Potential Antimalarial Drug Candidate from a Series of 2-Aminopyrazines by Optimization of Aqueous Solubility and Potency across the Parasite Life Cycle

scientific article published on 17 October 2016

Improved antiparasitic activity by incorporation of organosilane entities into half-sandwich ruthenium(II) and rhodium(III) thiosemicarbazone complexes

scientific article

Improvement of the chemical inhibition phenotyping assay by cross-reactivity correction

scientific article

Insights into Integrated Lead Generation and Target Identification in Malaria and Tuberculosis Drug Discovery

scientific article

Intestinal Transport Characteristics and Metabolism of C-Glucosyl Dihydrochalcone, Aspalathin

scientific article published on 30 March 2017

Investigating Sulfoxide-to-Sulfone Conversion as a Prodrug Strategy for a Phosphatidylinositol 4-Kinase Inhibitor in a Humanized Mouse Model of Malaria.

scientific article published on 26 November 2018

Kojic acid derived hydroxypyridinone-chloroquine hybrids: synthesis, crystal structure, antiplasmodial activity and β-haematin inhibition

scientific article published on 14 June 2014

Linear free energy relationships predict coordination and π-stacking interactions of small molecules with ferriprotoporphyrin IX.

scientific article published on 26 February 2011

Meclonazepam analogues as potential new antihelmintic agents.

scientific article

Medicinal chemistry optimization of antiplasmodial imidazopyridazine hits from high throughput screening of a SoftFocus kinase library: part 1.

scientific article

Medicinal chemistry optimization of antiplasmodial imidazopyridazine hits from high throughput screening of a softfocus kinase library: part 2.

scientific article published on 23 October 2014

Metallocene antimalarials: the continuing quest

scientific article published on January 2008

Metallocene-based antimalarials: an exploration into the influence of the ferrocenyl moiety on in vitro antimalarial activity in chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum

scientific article published on August 2007

Molecular Structure of an Unexpected Binuclear Salicylaldimine Semicarbazone Palladium(II) Complex

Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box

scientific article published on 11 January 2021

New Verapamil Analogs Inhibit Intracellular Mycobacteria without Affecting the Functions of Mycobacterium-Specific T Cells

scientific article published on 7 December 2015

New developments in antiinfectives research for tropical infectious diseases

scientific article

New homochiral binaphthol-modified organolanthanide reagents for the enantioselective addition to aldehydes

article

New ketomethylene inhibitor analogues: synthesis and assessment of structural determinants for N-domain selective inhibition of angiotensin-converting enzyme

scientific article published on May 2012

Novel anti-plasmodial hits identified by virtual screening of the ZINC database

scientific article

Novel approaches to antimalarial drug discovery

scientific article published on June 2006

Novel inhibitors of the trypanosome alternative oxidase inhibit Trypanosoma brucei brucei growth and respiration

scientific article published on 28 November 2006

Novel ketomethylene inhibitors of angiotensin I-converting enzyme (ACE): inhibition and molecular modelling

scientific article

Novel orally active antimalarial thiazoles

scientific article

Novel tetracyclic structures from the synthesis of thiolactone-isatin hybrids

scientific article

Novel thiolactone-isatin hybrids as potential antimalarial and antitubercular agents

scientific article published on 2 March 2011

Novel web-based tools combining chemistry informatics, biology and social networks for drug discovery

scientific article published on 11 February 2009

Pharmacokinetic evaluation of lisinopril-tryptophan, a novel C-domain ACE inhibitor

scientific article published on 20 February 2014

Pharmacologically active metabolites, combination screening and target identification-driven drug repositioning in antituberculosis drug discovery

scientific article published on 16 June 2014

Physicochemical and drug metabolism characterization of a series of 4-aminoquinoline-3-hydroxypyridin-4-one hybrid molecules with antimalarial activity

scientific article published on October 2014

Plasmodial Kinase Inhibitors: License to Cure?

scientific article

Potent inhibition of CYP1A2 by Frutinone A, an active ingredient of the broad spectrum antimicrobial herbal extract from P. fruticosa

scientific article published on 25 April 2012

Preparation and Physicochemical Characterization of an Inclusion Complex Between Dimethylated β-Cyclodextrin and a Drug Lead From a New Class of Orally Active Antimalarial 3,5-Diaryl-2-Aminopyridines

scientific article published on 15 September 2016

Primaquine-pyrimidine hybrids: synthesis and dual-stage antiplasmodial activity

scientific article

Purification of human malaria parasite hypoxanthine guanine xanthine phosphoribosyltransferase (HGXPRT) using immobilized Reactive Red 120.

scientific article published on 5 October 2006

Pyrimidine-chloroquinoline hybrids: Synthesis and antiplasmodial activity

scientific article published on 9 February 2018

Pyrrolo[3,4-c]pyridine-1,3(2H)-diones: A Novel Antimycobacterial Class Targeting Mycobacterial Respiration

scientific article published on 9 November 2015

Quinoline antimalarials containing a dibemethin group are active against chloroquinone-resistant Plasmodium falciparum and inhibit chloroquine transport via the P. falciparum chloroquine-resistance transporter (PfCRT).

scientific article

Quinoline-pyrimidine hybrids: synthesis, antiplasmodial activity, SAR, and mode of action studies

scientific article published on 31 December 2013

Recent approaches to chemical discovery and development against malaria and the neglected tropical diseases human African trypanosomiasis and schistosomiasis

scientific article published on 11 July 2014

Recent updates in the discovery and development of novel antimalarial drug candidates

article

Reversal of chloroquine resistance in Plasmodium falciparum by 9H-xanthene derivatives

scientific article published on August 2005

Reversed chloroquines based on the 3,4-dihydropyrimidin-2(1H)-one scaffold: synthesis and evaluation for antimalarial, beta-haematin inhibition, and cytotoxic activity

scientific article published on November 2008

Reversed isoniazids: Design, synthesis and evaluation against Mycobacterium tuberculosis

scientific article published on 29 December 2017

Structure-Activity Relationship Studies of Orally Active Antimalarial 2,4-Diamino-thienopyrimidines

scientific article published on 31 August 2015

Structure-activity relationship studies of antiplasmodial aminomethylthiazoles

scientific article published on 2 October 2014

Structure-activity relationship studies of antiplasmodial cyclometallated ruthenium(II), rhodium(III) and iridium(III) complexes of 2-phenylbenzimidazoles

scholarly article by Laa-Iqa Rylands et al published January 2019 in European Journal of Medicinal Chemistry

Structure-activity relationship studies of orally active antimalarial 3,5-substituted 2-aminopyridines

scientific article

Structure-activity relationships for ferriprotoporphyrin IX association and β-hematin inhibition by 4-aminoquinolines using experimental and ab initio methods

scientific article published on 23 April 2013

Structure-activity-relationship studies around the 2-amino group and pyridine core of antimalarial 3,5-diarylaminopyridines lead to a novel series of pyrazine analogues with oral in vivo activity

scientific article published on 29 October 2013

Studies in iridoid synthesis. Chemoselective transformations of cis-1,2,4,6-tetrahydrophthalic anhydride

scientific article published on 20 December 2007

Synthesis and Evaluation of a Carbosilane Congener of Ferroquine and Its Corresponding Half-Sandwich Ruthenium and Rhodium Complexes for Antiplasmodial and β-Hematin Inhibition Activity

Synthesis and antiplasmodial and antimycobacterial evaluation of new nitroimidazole and nitroimidazooxazine derivatives

scientific article

Synthesis and antiplasmodial evaluation of novel (4-aminobutyloxy)quinolines

scientific article published on November 2012

Synthesis and biological characterisation of ester and amide derivatives of fusidic acid as antiplasmodial agents

scientific article published on 25 November 2016

Synthesis and biological evaluation of 2-aminothiazole derivatives as antimycobacterial and antiplasmodial agents

scientific article published on 12 December 2013

Synthesis and biological evaluation of 4 arylcoumarin analogues as tubulin-targeting antitumor agents

scientific article published on 27 January 2017

Synthesis and biological evaluation of aryl-oxadiazoles as inhibitors of Mycobacterium tuberculosis.

scientific article published on 13 April 2018

Synthesis and biological evaluation of phenolic Mannich bases of benzaldehyde and (thio)semicarbazone derivatives against the cysteine protease falcipain-2 and a chloroquine resistant strain of Plasmodium falciparum

scientific article published on 29 September 2006

Synthesis and evaluation of hybrid drugs for a potential HIV/AIDS-malaria combination therapy

scientific article

Synthesis and evaluation of isatins and thiosemicarbazone derivatives against cruzain, falcipain-2 and rhodesain

scientific article published in October 2003

Synthesis and evaluation of new polynuclear organometallic Ru(II), Rh(III) and Ir(III) pyridyl ester complexes as in vitro antiparasitic and antitumor agents

scientific article published on January 2014

Synthesis and evaluation of phenylequine for antimalarial activity in vitro and in vivo

scientific article

Synthesis and in vitro and in vivo pharmacological evaluation of new 4-aminoquinoline-based compounds

scientific article

Synthesis and in vitro antimalarial and antitubercular activity of gold(III) complexes containing thiosemicarbazone ligands

Synthesis and in vitro evaluation of gold(I) thiosemicarbazone complexes for antimalarial activity

scientific article published on July 2010

Synthesis and structure-activity relationships of parasiticidal thiosemicarbazone cysteine protease inhibitors against Plasmodium falciparum, Trypanosoma brucei, and Trypanosoma cruzi

scientific article

Synthesis and structure-activity-relationship studies of thiazolidinediones as antiplasmodial inhibitors of the Plasmodium falciparum cysteine protease falcipain-2.

scientific article published on 2 December 2014

Synthesis and synergistic antimycobacterial screening of chlorpromazine and its metabolites

Synthesis of 2-(aminomethyl)aziridines and their microwave-assisted ring opening to 1,2,3-triaminopropanes as novel antimalarial pharmacophores

scientific article published in December 2010

Synthesis of 2-amino-3-arylpropan-1-ols and 1-(2,3-diaminopropyl)-1,2,3-triazoles and evaluation of their antimalarial activity

scientific article published on 30 December 2011

Synthesis of 2-aminomethyl-4-phenyl-1-azabicyclo[2.2.1]heptanes via LiAlH₄-induced reductive cyclization of 2-(4-chloro-2-cyano-2-phenylbutyl)aziridines and evaluation of their antimalarial activity

scientific article published on 20 December 2012

Synthesis of 4-aminoquinoline-pyrimidine hybrids as potent antimalarials and their mode of action studies

scientific article published on 10 June 2013

Synthesis of aminoquinoline-based aminoalcohols and oxazolidinones and their antiplasmodial activity

scientific article published on 11 January 2012

Synthesis of functionalized 3-, 5-, 6- and 8-aminoquinolines via intermediate (3-pyrrolin-1-yl)- and (2-oxopyrrolidin-1-yl)quinolines and evaluation of their antiplasmodial and antifungal activity

scientific article published on 12 December 2014

Synthesis of fusidic acid bioisosteres as antiplasmodial agents and molecular docking studies in the binding site of elongation factor-G

Synthesis of halogenated 4-quinolones and evaluation of their antiplasmodial activity

scientific article published on 4 January 2014

Synthesis of new 7-chloroquinolinyl thioureas and their biological investigation as potential antimalarial and anticancer agents

scientific article published on 19 August 2007

Synthesis of new verapamil analogues and their evaluation in combination with rifampicin against Mycobacterium tuberculosis and molecular docking studies in the binding site of efflux protein Rv1258c

scientific article published on 16 May 2014

Synthesis of novel 2-alkoxy-3-amino-3-arylpropan-1-ols and 5-alkoxy-4-aryl-1,3-oxazinanes with antimalarial activity

scientific article published on July 2009

Synthesis of novel keto-ACE analogues as domain-selective angiotensin I-converting enzyme inhibitors

scientific article

Synthesis of totarol amino alcohol derivatives and their antiplasmodial activity and cytotoxicity

scientific article published on October 2003

Synthesis, Antiplasmodial Activity, and β-Hematin Inhibition of Hydroxypyridone-Chloroquine Hybrids

scientific article

Synthesis, Characterization, and Pharmacological Evaluation of Silicon-Containing Aminoquinoline Organometallic Complexes As Antiplasmodial, Antitumor, and Antimycobacterial Agents

scholarly article by Yiqun Li et al published 31 December 2012 in Organometallics

Synthesis, Structure and in Vitro Biological Screening of Palladium(II) Complexes of Functionalised Salicylaldimine Thiosemicarbazones as Antimalarial and Anticancer Agents

Synthesis, antimalarial and antitubercular activity of acetylenic chalcones

scientific article published on 23 December 2009

Synthesis, antimycobacterial evaluation and pharmacophore modeling of analogues of the natural product formononetin

scientific article published on 28 April 2015

Synthesis, antiplasmodial activity and mechanistic studies of pyrimidine-5-carbonitrile and quinoline hybrids

scientific article published on 12 June 2015

Synthesis, biological evaluation and mechanistic studies of totarol amino alcohol derivatives as potential antimalarial agents

scientific article published on 3 December 2011

Synthesis, characterization and antiplasmodial evaluation of cyclopalladated thiosemicarbazone complexes

Synthetic medicinal chemistry of selected antimalarial natural products

scientific article

Tetrazole-based deoxyamodiaquines: synthesis, ADME/PK profiling and pharmacological evaluation as potential antimalarial agents

scientific article published on 11 July 2013

The Next Generation Scientist program: capacity-building for future scientific leaders in low- and middle-income countries

scientific article published on 10 October 2018

The Role of Natural Products in Drug Discovery and Development against Neglected Tropical Diseases

scientific article published on 31 December 2016

The design, synthesis, in silico ADME profiling, antiplasmodial and antimycobacterial evaluation of new arylamino quinoline derivatives

scientific article published on 7 September 2012

The development and validation of an LC-MS/MS method for the determination of a new anti-malarial compound (TK900D) in human whole blood and its application to pharmacokinetic studies in mice

scientific article published on 31 January 2014

The new permeability pathways: targets and selective routes for the development of new antimalarial agents

scientific article

The significance of the C(α) substituent in the selective inhibition of matrix metalloproteinases 1 and 9.

scientific article

The state of the art in anti-malarial drug discovery and development

scientific article published on January 2011

The synthesis and antiparasitic activity of aryl- and ferrocenyl-derived thiosemicarbazone ruthenium(II)-arene complexes

scientific article published on April 2013

The synthesis of parasitic cysteine protease and trypanothione reductase inhibitors

scientific article

Thiosemicarbazone Salicylaldiminato-Palladium(II)-Catalyzed Mizoroki-Heck Reactions

article published in 2010

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