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List of works by Shaun K Olsen

A protein canyon in the FGF-FGF receptor dimer selects from an à la carte menu of heparan sulfate motifs

scientific article

Active site remodelling accompanies thioester bond formation in the SUMO E1

scientific article

Analysis of mutations in fibroblast growth factor (FGF) and a pathogenic mutation in FGF receptor (FGFR) provides direct evidence for the symmetric two-end model for FGFR dimerization

scientific article

Crystal Structure of the Nephila clavipes Major Ampullate Spidroin 1A N-terminal Domain Reveals Plasticity at the Dimer Interface

scientific article

Crystal Structure of the interleukin-15.interleukin-15 receptor alpha complex: insights into trans and cis presentation

scientific article

Crystal structure of a human ubiquitin E1-ubiquitin complex reveals conserved functional elements essential for activity

scientific article published in Journal of Biological Chemistry

Designed semisynthetic protein inhibitors of Ub/Ubl E1 activating enzymes.

scientific article published on February 2010

Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity

scientific article published on 25 November 2021

Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism

scientific article

Domain alternation and active site remodeling are conserved structural features of ubiquitin E1.

scientific article published on June 2017

Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs

scientific article

Homodimerization Controls the Fibroblast Growth Factor 9 Subfamily's Receptor Binding and Heparan Sulfate-Dependent Diffusion in the Extracellular Matrix

scientific article

Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity

scientific article

Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members

scientific article

Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme

scientific article published in Nature Communications

No Requirement of Trans Presentations of IL-15 for Human CD8 T Cell Proliferation ⬇️

scientific article published on October 6, 2010

PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis

scientific article published on 08 June 2021

Plasticity in Interactions of Fibroblast Growth Factor 1 (FGF1) N Terminus with FGF Receptors Underlies Promiscuity of FGF1

scientific article

Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family

scientific article

S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity.

scientific article published on 28 January 2017

Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain

scientific article

Structural basis for adenylation and thioester bond formation in the ubiquitin E1

scientific article published on 24 June 2019

Structural basis for fibroblast growth factor receptor activation

scientific article

Structural insights into E1 recognition and the ubiquitin-conjugating activity of the E2 enzyme Cdc34

scientific article published on 24 July 2019

Structural insights into the mechanism and E2 specificity of the RBR E3 ubiquitin ligase HHARI.

scientific article published on 08 August 2017

Structure of a Ubiquitin E1-E2 Complex: Insights to E1-E2 Thioester Transfer

scientific article

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