Search filters

List of works by Nicholas E. Dixon

A complex mechanism determines polarity of DNA replication fork arrest by the replication terminator complex of Bacillus subtilis.

scientific article

A direct proofreader-clamp interaction stabilizes the Pol III replicase in the polymerization mode

scientific article published on 22 February 2013

A gatekeeping function of the replicative polymerase controls pathway choice in the resolution of lesion-stalled replisomes

scientific article published on 03 December 2019

A molecular mousetrap determines polarity of termination of DNA replication in E. coli

scientific article

A novel zinc-binding fold in the helicase interaction domain of the Bacillus subtilis DnaI helicase loader

scientific article

A processed multidomain mycoplasma hyopneumoniae adhesin binds fibronectin, plasminogen, and swine respiratory cilia

scientific article published on 2 September 2010

A single subunit directs the assembly of the Escherichia coli DNA sliding clamp loader.

scientific article published on March 2010

A structural model for the Escherichia coli DnaB helicase based on electron microscopy data.

scientific article published on May 1995

A universal protein-protein interaction motif in the eubacterial DNA replication and repair systems.

scientific article

Amino-acid type identification in 15N-HSQC spectra by combinatorial selective 15N-labelling.

scientific article

An investigation into the interactions of gold nanoparticles and anti-arthritic drugs with macrophages, and their reactivity towards thioredoxin reductase

scientific article published on 28 September 2014

Application of electrospray ionization mass spectrometry to study the hydrophobic interaction between the epsilon and theta subunits of DNA polymerase III

scientific article published on 30 September 2004

Architecture and conservation of the bacterial DNA replication machinery, an underexploited drug target

scientific article published on March 2012

Assignment of paramagnetic (15)N-HSQC spectra by heteronuclear exchange spectroscopy

scientific article published on 10 November 2006

AtfA, a new factor in global regulation of transcription in Acinetobacter spp.

scientific article published on 31 July 2014

Backbone NMR assignments and secondary structure of the N-terminal domain of DnaB helicase from E. coli.

scientific article published in February 1998

Backbone assignment of fully protonated solid proteins by 1H detection and ultrafast magic-angle-spinning NMR spectroscopy.

scientific article

Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs

scientific article

Bacterial replisomes

article

Binding inhibitors of the bacterial sliding clamp by design

scientific article published on 14 July 2011

Bound or free: interaction of the C-terminal domain of Escherichia coli single-stranded DNA-binding protein (SSB) with the tetrameric core of SSB.

scientific article published on 18 March 2014

Cell-free protein synthesis for analysis by NMR spectroscopy

scientific article published on 01 January 2008

Cell-free protein synthesis in an autoinduction system for NMR studies of protein-protein interactions.

scientific article

Cell-free synthesis and combinatorial selective 15N-labeling of the cytotoxic protein amoebapore A from Entamoeba histolytica.

scientific article

Cell-free synthesis of 15N-labeled proteins for NMR studies

scientific article published in September 2005

Cell-free transcription/translation from PCR-amplified DNA for high-throughput NMR studies

scientific article published in January 2007

Chaperonin-encapsulation of proteins for NMR.

scientific article

Characterization of cleavage events in the multifunctional cilium adhesin Mhp684 (P146) reveals a mechanism by which Mycoplasma hyopneumoniae regulates surface topography

scientific article

Characterization of gibberellin receptor mutants of barley (Hordeum vulgare L.).

scientific article published on 11 February 2008

Chromium(V)-induced cleavage of DNA: are chromium(V) complexes the active carcinogens in chromium(VI)-induced cancers?

scientific article published on 01 July 1989

Conservation of eubacterial replicases

scientific article

Corrigendum to "Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens" [J. Struct. Biol. 204 (3) (2018) 396-405]

scientific article published on 13 May 2019

Crystal Structure of Escherichia coli QOR Quinone Oxidoreductase Complexed with NADPH ⬇️

scientific article published on June 16, 1995

Crystal and solution structures of the helicase-binding domain of Escherichia coli primase

scientific article

Crystal structure of cytoplasmic Escherichia coli peptidyl-prolyl isomerase: evidence for decreased mobility of loops upon complexation

scientific article

Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens

scientific article published on 23 October 2018

Crystallization and low temperature diffraction studies of the DNA binding domain of the single-stranded DNA binding protein from Escherichia coli.

scientific article published on July 1994

Crystallization and preliminary X-ray diffraction studies on a soluble Escherichia coli quinone oxidoreductase.

scientific article

Crystallization and preliminary X-ray investigation of the Escherichia coli molecular chaperone cpn60 (GroEL).

scientific article

DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs

scientific article

Defining the structural basis of human plasminogen binding by streptococcal surface enolase

scientific article published on 10 April 2009

Design of DNA rolling-circle templates with controlled fork topology to study mechanisms of DNA replication

scientific article published on 18 July 2018

Development of a single-stranded DNA-binding protein fluorescent fusion toolbox

scientific article published on 06 May 2020

Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach

scientific article

Disproportionation and Nuclease Activity of Bis[2-ethyl-2-hydroxybutanoato(2−)]oxochromate(V) in Neutral Aqueous Solutions1

scientific article published on 01 February 2000

Disproportionation of a model chromium(V) complex causes extensive chromium(III)-DNA binding in vitro.

scientific article published in August 2001

Distribution of the flavohaemoglobin, HMP, between periplasm and cytoplasm in Escherichia coli

scientific article published on 01 January 1995

Dynamics of Proofreading by the E. coli Pol III Replicase.

scientific article published on 16 October 2017

E. coli DNA replication in the absence of free β clamps

scientific article

Effect of protein stabilization on charge state distribution in positive- and negative-ion electrospray ionization mass spectra.

scientific article published on 19 June 2007

Efficient chi-tensor determination and NH assignment of paramagnetic proteins

scientific article published on 10 June 2006

Enriched sources of Escherichia coli replication proteins. The dnaG primase is a zinc metalloprotein

scientific article published on August 17, 1992

Escherichia coli PII protein: purification, crystallization and oligomeric structure.

scientific article published on January 1994

Escherichia coli single-stranded DNA-binding protein: nanoESI-MS studies of salt-modulated subunit exchange and DNA binding transactions

scientific article

Essential biological processes of an emerging pathogen: DNA replication, transcription, and cell division in Acinetobacter spp

scientific article

Exchange between Escherichia coli polymerases II and III on a processivity clamp

scientific article published on 10 December 2015

Expression, purification, crystallization, and NMR studies of the helicase interaction domain of Escherichia coli DnaG primase

scientific article published in February 2004

Fast structure-based assignment of 15N HSQC spectra of selectively 15N-labeled paramagnetic proteins

scientific article published in March 2004

Flexibility revealed by the 1.85 A crystal structure of the beta sliding-clamp subunit of Escherichia coli DNA polymerase III

scientific article

Fragment-Based Discovery of Inhibitors of the Bacterial DnaG-SSB Interaction

scientific article published on 22 February 2018

Helicase binding to DnaI exposes a cryptic DNA-binding site during helicase loading in Bacillus subtilis

scientific article

High-yield cell-free protein synthesis for site-specific incorporation of unnatural amino acids at two sites.

scientific article

Hydrolysis of the 5'-p-nitrophenyl ester of TMP by the proofreading exonuclease (epsilon) subunit of Escherichia coli DNA polymerase III.

scientific article published in April 2002

Improving a natural enzyme activity through incorporation of unnatural amino acids.

scientific article published on 16 December 2010

In Vitro Plasmid DNA Cleavage by Chromium(V) and -(IV) 2-Hydroxycarboxylato Complexes

scientific article published on 01 April 1999

In VivoProtein Cyclization Promoted by a Circularly PermutedSynechocystissp. PCC6803 DnaB Mini-intein

scientific article published in Journal of Biological Chemistry

Incorporation of chlorinated analogues of aliphatic amino acids during cell-free protein synthesis.

scientific article published on 22 November 2010

Inhibition of Jack Bean urease (EC 3.5.1.5) by acetohydroxamic acid and by phosphoramidate. An equivalent weight for urease.

scientific article published in July 1975

Inhibition of protein interactions with the beta 2 sliding clamp of Escherichia coli DNA polymerase III by peptides from beta 2-binding proteins

scientific article

Integron-associated mobile gene cassettes code for folded proteins: the structure of Bal32a, a new member of the adaptable alpha+beta barrel family.

scientific article

Internal symmetry of the molecular chaperone cpn60 (GroEL) determined by X-ray crystallography.

scientific article

Intramolecular binding mode of the C-terminus of Escherichia coli single-stranded DNA binding protein determined by nuclear magnetic resonance spectroscopy

scientific article

Kinetic and crystallographic analysis of mutant Escherichia coli aminopeptidase P: insights into substrate recognition and the mechanism of catalysis

scientific article

Lanthanide labeling offers fast NMR approach to 3D structure determinations of protein-protein complexes.

scientific article

Letter: Jack bean urease (EC 3.5.1.5). A metalloenzyme. A simple biological role for nickel?

scientific article published on 01 July 1975

Loading dynamics of a sliding DNA clamp

scientific article

Measurement of dissociation constants of high-molecular weight protein-protein complexes by transferred 15N-relaxation

scientific article

Metal ions in enzymes using ammonia or amides

scientific article published on March 19, 1976

Mhp107 is a member of the multifunctional adhesin family of Mycoplasma hyopneumoniae.

scientific article published on 18 January 2011

Mhp182 (P102) binds fibronectin and contributes to the recruitment of plasmin(ogen) to the Mycoplasma hyopneumoniae cell surface

scientific article published on 09 November 2011

Molecular cloning of the phosphate (inorganic) transport (pit) gene of Escherichia coli K12. Identification of the pit+ gene product and physical mapping of the pit-gor region of the chromosome.

scientific article

Monomeric solution structure of the helicase-binding domain of Escherichia coli DnaG primase.

scientific article

Multiple classes and isoforms of the RNA polymerase recycling motor protein HelD

scientific article published on 01 November 2021

Multiple oligomeric forms of Escherichia coli DnaB helicase revealed by electrospray ionisation mass spectrometry.

scientific article

N-Labelled proteins by cell-free protein synthesis. Strategies for high-throughput NMR studies of proteins and protein-ligand complexes

scientific article published on 23 August 2006

NMR Spectroscopic Assignment of Backbone and Side-Chain Protons in Fully Protonated Proteins: Microcrystals, Sedimented Assemblies, and Amyloid Fibrils

scientific article published on 16 November 2016

NMR analysis of in vitro-synthesized proteins without purification: a high-throughput approach.

scientific article

NMR detection of protein 15N spins near paramagnetic lanthanide ions

scientific article published on 01 January 2007

Nanometer-scale distance measurements in proteins using Gd3+ spin labeling

scientific article published in July 2010

Nuclease dead Cas9 is a programmable roadblock for DNA replication

scientific article published on 16 September 2019

Optimization of an Escherichia coli system for cell-free synthesis of selectively N-labelled proteins for rapid analysis by NMR spectroscopy

scientific article published in October 2004

Polymerase exchange on single DNA molecules reveals processivity clamp control of translesion synthesis

scientific article

Precise limits of the N-terminal domain of DnaB helicase determined by NMR spectroscopy

scientific article published on 01 February 1997

Preliminary X-ray crystallographic and NMR studies on the exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III

scientific article published on 01 August 2000

Prime-time looping

scientific article published in Nature

Priming the engine of DNA synthesis.

scientific article

Probing molecular choreography through single-molecule biochemistry

scientific article published in December 2015

Proofreading exonuclease on a tether: the complex between the E. coli DNA polymerase III subunits α, epsilon, θ and β reveals a highly flexible arrangement of the proofreading domain

scientific article

Protein residue linking in a single spectrum for magic-angle spinning NMR assignment

scientific article

Protein--protein interactions in the eubacterial replisome

scientific article

Proteomic dissection of DNA polymerization

scientific article

Rational Design of a 310 -Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp

scientific article published on 19 July 2018

Real-time single-molecule observation of rolling-circle DNA replication

scientific article

Recycling of single-stranded DNA-binding protein by the bacterial replisome

scientific article published on 01 May 2019

Repeat regions R1 and R2 in the P97 paralogue Mhp271 of Mycoplasma hyopneumoniae bind heparin, fibronectin and porcine cilia

scientific article

Replication termination in Escherichia coli: structure and antihelicase activity of the Tus-Ter complex

scientific article

Replicative DNA polymerases

scientific article published on June 2013

Replisome speed determines the efficiency of the Tus-Ter replication termination barrier

scientific article

Roquin binds microRNA-146a and Argonaute2 to regulate microRNA homeostasis

scientific journal article

Sequence-specific and stereospecific assignment of methyl groups using paramagnetic lanthanides.

scientific article published on 12 October 2007

Single-molecule studies of fork dynamics in Escherichia coli DNA replication

scientific article published on 27 January 2008

Single-molecule studies of fork dynamics in Escherichia coli DNA replication

scientific article published on 01 September 2008

Single-molecule visualization of fast polymerase turnover in the bacterial replisome

scientific article published on 22 April 2017

Site-specific covalent attachment of DNA to proteins using a photoactivatable Tus-Ter complex

scientific article

Site-specific labelling of proteins with a rigid lanthanide-binding tag.

scientific article

Solution structure of Domains IVa and V of the   subunit of Escherichia coli DNA polymerase III and interaction with the   subunit

scientific article

Stabilization of native protein fold by intein-mediated covalent cyclization

scientific article published on 18 January 2005

Stable high-copy-number bacteriophage lambda promoter vectors for overproduction of proteins in Escherichia coli.

scientific article

Strand separation establishes a sustained lock at the Tus-Ter replication fork barrier.

scientific article

Strand switching of a replicative DNA helicase promoted by the E. coli primosome.

scientific article

Structural basis for proofreading during replication of the Escherichia coli chromosome

scientific article

Structure and function of a spectrin-like regulator of bacterial cytokinesis

scientific article

Structure and mechanism of a proline-specific aminopeptidase from Escherichia coli

scientific article

Structure determination of protein-ligand complexes by transferred paramagnetic shifts.

scientific article

Structure of the Escherichia coli signal transducing protein PII

scientific article

Structure of the theta subunit of Escherichia coli DNA polymerase III in complex with the epsilon subunit

scientific article

Structure-activity relationships of pyrazole-4-carbodithioates as antibacterials against methicillin-resistant Staphylococcus aureus

scientific article published on 03 October 2018

Synthesis and properties of crosslinked recombinant pro-resilin

scientific article

The 92-min region of the Escherichia coli chromosome: location and cloning of the ubiA and alr genes.

scientific article published on July 1993

The DnaB.DnaC complex: a structure based on dimers assembled around an occluded channel.

scientific article

The E. coli DNA Replication Fork

scientific article published on 13 May 2016

The ROQUIN family of proteins localizes to stress granules via the ROQ domain and binds target mRNAs

scientific article

The proofreading exonuclease subunit epsilon of Escherichia coli DNA polymerase III is tethered to the polymerase subunit alpha via a flexible linker

scientific article published on 28 July 2008

The symmetry of Escherichia coli cpn60 (GroEL) determined by X-ray crystallography.

scientific article

The unstructured C-terminus of the tau subunit of Escherichia coli DNA polymerase III holoenzyme is the site of interaction with the alpha subunit

scientific article published on 13 March 2007

Translational incorporation of L-3,4-dihydroxyphenylalanine into proteins

scientific article published in June 2005

Two mechanisms coordinate replication termination by the Escherichia coli Tus-Ter complex

scientific article published on 24 May 2015

Ultrasensitive detection of antibodies using a new Tus-Ter-lock immunoPCR system

scientific article published in July 2010

Use of electrospray ionization mass spectrometry to study binding interactions between a replication terminator protein and DNA

scientific article

Weak alignment of paramagnetic proteins warrants correction for residual CSA effects in measurements of pseudocontact shifts

scientific article published on 01 December 2005

Weak and Transient Protein Interactions Determined by Solid-State NMR.

scientific article

What is all this fuss about Tus? Comparison of recent findings from biophysical and biochemical experiments

scientific article published on 6 November 2017

pH-controlled quaternary states of hexameric DnaB helicase

scientific article published on 01 October 2000

Paulina is supported by:

About Paulina

Help