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List of works by Stuart M. Brierley

5-HT(3) and 5-HT(4) receptors contribute to the anti-motility effects of Garcinia buchananii bark extract in the guinea-pig distal colon

scientific article published on 10 November 2011

888 α-Conotoxin Vc1.1 Targets GABAB Receptors Modulating CaV2.2 and CaV2.3 Calcium Channels in Sensory Pathways Mediating Chronic Visceral Pain

A novel role for TRPM8 in visceral afferent function.

scientific article

Acid sensing ion channels 2 and 3 are required for inhibition of visceral nociceptors by benzamil.

scientific article

Activation of colo-rectal high-threshold afferent nerves by Interleukin-2 is tetrodotoxin-sensitive and upregulated in a mouse model of chronic visceral hypersensitivity.

scientific article published on 14 October 2015

Acute colitis chronically alters immune infiltration mechanisms and sensory neuro-immune interactions

scientific article published on 15 November 2016

All ahead stop! How intestinal motility adapts to cope with inflammation induced ulceration

scientific article published on 01 March 2010

Altered Ion Channel/Receptor Expression and Function in Extrinsic Sensory Neurons: The Cause of and Solution to Chronic Visceral Pain?

scientific article

Apelin targets gut contraction to control glucose metabolism via the brain

scientific article

CO-EXPRESSION OF μ AND ∂ OPIOID RECEPTORS BY MOUSE COLONIC NOCICEPTORS.

scientific article published on 26 March 2018

Chronic linaclotide treatment reduces colitis-induced neuroplasticity and reverses persistent bladder dysfunction

article

Colonic afferent input and dorsal horn neuron activation differs between the thoracolumbar and lumbosacral spinal cord

scientific article published on 12 June 2019

Conopeptide-Derived κ-Opioid Agonists (Conorphins): Potent, Selective, and Metabolic Stable Dynorphin A Mimetics with Antinociceptive Properties.

scientific article published on 9 February 2016

Contribution of membrane receptor signalling to chronic visceral pain

scientific article published on 22 February 2018

Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain

scientific article

Deletion of interleukin-6 signal transducer gp130 in small sensory neurons attenuates mechanonociception and down-regulates TRPA1 expression.

scientific article

Differential chemosensory function and receptor expression of splanchnic and pelvic colonic afferents in mice.

scientific article published on 9 June 2005

Emerging receptor target in the pharmacotherapy of irritable bowel syndrome with constipation.

scientific article published on July 2013

Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways.

scientific article published on 21 June 2017

Expression of taste molecules in the upper gastrointestinal tract in humans with and without type 2 diabetes.

scientific article published on 27 November 2008

G-CSF Receptor Blockade Ameliorates Arthritic Pain and Disease.

scientific article

Garcinia buchananii bark extract is an effective anti-diarrheal remedy for lactose-induced diarrhea

scientific article published on 27 May 2012

Gastric vagal afferent modulation by leptin is influenced by food intake status.

scientific article published on 24 December 2012

Ghrelin selectively reduces mechanosensitivity of upper gastrointestinal vagal afferents.

scientific article

Guanylate cyclase-C receptor activation: unexpected biology ⬇️

scientific article published on November 3, 2012

Gut nociceptors: sentinels promoting host defense

scientific article published on 01 April 2020

Identifying the Ion Channels Responsible for Signaling Gastro-Intestinal Based Pain

scientific article

Identifying unique subtypes of spinal afferent nerve endings within the urinary bladder of mice

scientific article

Immune derived opioidergic inhibition of viscerosensory afferents is decreased in Irritable Bowel Syndrome patients

scientific article published on 23 July 2014

Increased κ-opioid receptor expression and function during chronic visceral hypersensitivity

scientific article

Innate immune response to bacterial urinary tract infection sensitises high-threshold bladder afferents and recruits silent nociceptors

scientific article published on 01 January 2020

Involvement of galanin receptors 1 and 2 in the modulation of mouse vagal afferent mechanosensitivity

scientific article published on 12 July 2007

Involvement of metabotropic glutamate 5 receptor in visceral pain.

scientific article published on 15 October 2007

Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3',5'-monophosphate

scientific article

Linaclotide treatment reduces endometriosis-associated vaginal hyperalgesia and mechanical allodynia through viscerovisceral cross-talk

scientific article published on 01 November 2019

Localization and comparative analysis of acid-sensing ion channel (ASIC1, 2, and 3) mRNA expression in mouse colonic sensory neurons within thoracolumbar dorsal root ganglia.

scientific article published in February 2007

Mechanisms Underlying Overactive Bladder and Interstitial Cystitis/Painful Bladder Syndrome

scientific article published on 12 December 2018

Molecular basis of mechanosensitivity.

scientific article published on 15 August 2009

Multiple sodium channel isoforms mediate the pathological effects of Pacific ciguatoxin-1.

scientific article

NKA enhances bladder-afferent mechanosensitivity via urothelial and detrusor activation

article published in 2018

NaV 1.6 regulates excitability of mechanosensitive sensory neurons

scientific article published on 13 May 2019

NaV1.1 inhibition can reduce visceral hypersensitivity

scientific article published on 07 June 2018

Neuroplasticity and dysfunction after gastrointestinal inflammation

scientific article published on 08 July 2014

Pain-Causing Venom Peptides: Insights into Sensory Neuron Pharmacology

scientific article published on 27 December 2017

Potentiation of mouse vagal afferent mechanosensitivity by ionotropic and metabotropic glutamate receptors

scientific article published on 31 August 2006

Protease-Activated Receptor 1 is Implicated in Irritable Bowel Syndrome Mediators-Induced Signalling to Thoracic Human Sensory Neurons

scientific article published on 15 March 2018

Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome

article published in the Proceedings of the National Academy of Sciences of the United States of America

Purinergic receptor mediated calcium signalling in urothelial cells

scientific article published on 06 November 2019

Selective role for TRPV4 ion channels in visceral sensory pathways.

scientific article published on 31 January 2008

Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain

scientific journal article

Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain

scientific article published in Nature Communications

Sensory neuro-immune interactions differ between irritable bowel syndrome subtypes

scientific article

Serotonin exerts a direct modulatory role on bladder afferent firing in mice

scientific article published on 13 October 2019

Small bowel homing T cells are associated with symptoms and delayed gastric emptying in functional dyspepsia

scientific article

Spinal Afferent Innervation of the Colon and Rectum

scientific article published on 04 December 2018

Splanchnic and pelvic mechanosensory afferents signal different qualities of colonic stimuli in mice

scientific article published on 01 July 2004

Sprouting of colonic afferent central terminals and increased spinal mitogen-activated protein kinase expression in a mouse model of chronic visceral hypersensitivity

article

Structure-Activity Studies of Cysteine-Rich α-Conotoxins that Inhibit High-Voltage-Activated Calcium Channels via GABA(B) Receptor Activation Reveal a Minimal Functional Motif.

scientific article

Structure–Activity Studies Reveal the Molecular Basis for GABAB-Receptor Mediated Inhibition of High Voltage-Activated Calcium Channels by α-Conotoxin Vc1.1

scientific article published on 25 May 2018

TRPA1 contributes to specific mechanically activated currents and sensory neuron mechanical hypersensitivity.

scientific article published on 9 May 2011

Tetrodotoxin-sensitive voltage-gated sodium channels regulate bladder afferent responses to distension

article

The Hot Mustard Receptor's Role in Gut Motor Function

scientific article published on 22 June 2011

The ion channel ASIC1 contributes to visceral but not cutaneous mechanoreceptor function.

scientific article published in December 2004

The ion channel TRPA1 is required for normal mechanosensation and is modulated by algesic stimuli

scientific article published on 24 July 2009

Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia.

scientific article published on 6 March 2008

Translating peripheral bladder afferent mechanosensitivity to neuronal activation within the lumbosacral spinal cord of mice

scientific article published on 01 April 2019

Trefoil Factor Family: Unresolved Questions and Clinical Perspectives.

scientific article published on 18 February 2019

Use of natural products in gastrointestinal therapies

scientific article published on October 11, 2011

Visceral Pain

scientific article published on 31 October 2018

Visualising vagal afferent neurons and their terminals whilst silencing TRPV1.

scientific article published in November 2010

Voltage-gated sodium channels: (NaV )igating the field to determine their contribution to visceral nociception.

scientific article published on 9 January 2018

α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABAB receptors.

scientific article published on 17 February 2016

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