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List of works by Alessandro Doria

A Genetic Locus on Chromosome 2q24 Predicting Peripheral Neuropathy Risk in Type 2 Diabetes: Results From the ACCORD and BARI 2D Studies

scientific article published on 24 May 2019

A common haplotype at the CD36 locus is associated with high free fatty acid levels and increased cardiovascular risk in Caucasians

scientific article published on 28 July 2004

A functional variant in the gene 3' untranslated region regulates HSP70 expression and is a potential candidate for insulin resistance-related abnormalities

scientific article published on 21 August 2009

A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples

scientific article

A polymorphism at the IL6ST (gp130) locus is associated with traits of the metabolic syndrome.

scientific article published in January 2008

A visfatin promoter polymorphism is associated with low-grade inflammation and type 2 diabetes.

scientific article published in December 2006

Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance

scientific article published on 6 January 2013

Activation of human brown adipose tissue by a β3-adrenergic receptor agonist.

scientific article

Activity and expression of the Na+/H+ exchanger in human endothelial cells cultured in high glucose

scientific article published on 01 July 1995

Adiponectin genetic variability, plasma adiponectin, and cardiovascular risk in patients with type 2 diabetes

scientific article published in May 2006

An association between NIDDM and a GAA trinucleotide repeat polymorphism in the X25/frataxin (Friedreich's ataxia) gene

article

Angiotensin I-converting enzyme (ACE): estimation of DNA haplotypes in unrelated individuals using denaturing gradient gel blots

scientific article published on 01 August 1994

Angiotensinogen polymorphism M235T, hypertension, and nephropathy in insulin-dependent diabetes

scientific article published on 01 May 1996

Association between a genetic variant related to glutamic acid metabolism and coronary heart disease in individuals with type 2 diabetes

scientific article published on August 2013

Association of circulating levels of nicotinamide phosphoribosyltransferase (NAMPT/Visfatin) and of a frequent polymorphism in the promoter of the NAMPT gene with coronary artery disease in diabetic and non-diabetic subjects ⬇️

scientific article published on August 22, 2013

Association of hGrb10 genetic variations with type 2 diabetes in Caucasian subjects.

scientific article

Association of the Q121 variant of ENPP1 gene with decreased kidney function among patients with type 2 diabetes.

scientific article

CTLA4-Ig in B7-1-positive diabetic and non-diabetic kidney disease

scientific article published on 26 September 2015

Can existing drugs approved for other indications retard renal function decline in patients with type 1 diabetes and nephropathy?

scientific article published on September 2012

Circulating TNF receptors 1 and 2 predict ESRD in type 2 diabetes

scientific article published on 19 January 2012

Circulating high molecular weight adiponectin isoform is heritable and shares a common genetic background with insulin resistance in nondiabetic White Caucasians from Italy: evidence from a family-based study

scientific article

Clinical factors associated with resistance to microvascular complications in diabetic patients of extreme disease duration: the 50-year medalist study

scientific article published on 16 May 2007

Clustering of risk factors in hypertensive insulin-dependent diabetics with high sodium-lithium countertransport

scientific article published on 01 April 1992

Codon 972 polymorphism in the insulin receptor substrate-1 gene, obesity, and risk of noninsulin-dependent diabetes mellitus

scientific article published on 01 April 1996

Common haplotypes at the adiponectin receptor 1 (ADIPOR1) locus are associated with increased risk of coronary artery disease in type 2 diabetes

scientific article published on 01 October 2006

DdeI polymorphism in the AGTR1 gene

scientific article published on 01 August 1994

Diabetes susceptibility at IDDM2 cannot be positively mapped to the VNTR locus of the insulin gene

scientific article published on 01 May 1996

Diabetes: Lowering serum uric acid levels to prevent kidney failure

article published in 2011

Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools

scientific article

Early progressive renal decline precedes the onset of microalbuminuria and its progression to macroalbuminuria.

scientific article published on 12 August 2013

Elevated C-reactive protein levels do not correspond to autoimmunity in type 1 diabetes

scientific article published on 01 November 2004

Examination of PPP1R3B as a candidate gene for the type 2 diabetes and MODY loci on chromosome 8p23.

scientific article

Exclusion of insulin receptor substrate 2 (IRS-2) as a major locus for early-onset autosomal dominant type 2 diabetes

scientific article published on 01 March 1999

Fatty acid translocase (FAT/CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion.

scientific article published on February 2005

GRB10 gene and type 2 diabetes in Whites.

scientific article

Genetic Predictors of Cardiovascular Mortality During Intensive Glycemic Control in Type 2 Diabetes: Findings From the ACCORD Clinical Trial

scientific article

Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial

scientific article published on 27 September 2018

Genetic Variant at the GLUL Locus Predicts All-Cause Mortality in Patients With Type 2 Diabetes

scientific article published on 12 February 2015

Genetic Variants in CPA6 and PRPF31 are Associated with Variation in Response to Metformin in Individuals with Type 2 Diabetes.

scientific article published on 12 April 2018

Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.

scientific article published on 24 July 2017

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice

scientific article published on 26 July 2009

Genetic influences of adiponectin on insulin resistance, type 2 diabetes, and cardiovascular disease.

scientific article published on 15 February 2007

Genetic markers of increased susceptibility to diabetic nephropathy.

scientific article

Genetic modifiers of the age at diagnosis of diabetes (MODY3) in carriers of hepatocyte nuclear factor-1alpha mutations map to chromosomes 5p15, 9q22, and 14q24.

scientific article published in August 2003

Genetic predisposition to diabetic nephropathy. Evidence for a role of the angiotensin I--converting enzyme gene

scientific article published on 01 May 1994

Genetic predisposition to dyslipidemia and type 2 diabetes risk in two prospective cohorts

scientific article published on 7 February 2012

Genetic susceptibility to coronary heart disease in type 2 diabetes: 3 independent studies

scientific article published on December 2011

Genetic variability at the leptin receptor (LEPR) locus is a determinant of plasma fibrinogen and C-reactive protein levels

scientific article published on 03 April 2006

Genetic variants at the resistin locus and risk of type 2 diabetes in Caucasians

scientific article published on 01 September 2002

Genetic variation at the adiponectin locus and risk of type 2 diabetes in women

scientific article published in January 2004

Genetics of Diabetes Complications ⬇️

scientific article published on 01 December 2010

Genetics of Diabetic Micro- and Macrovascular Complications

article

Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes

scientific article

Genome-wide associations and metabolic disease: the big revolution

scientific article published on 01 July 2008

Genome-wide linkage screen for stature and body mass index in 3.032 families: evidence for sex- and population-specific genetic effects

scientific article published on 10 September 2008

Glutamine to arginine substitution at amino acid 84 of mammalian tribbles homolog TRIB3 and CKD in whites with type 2 diabetes

scientific article published in October 2007

Heritability of serum resistin and its genetic correlation with insulin resistance-related features in nondiabetic Caucasians.

scientific article published on 2 May 2006

High-normal serum uric acid increases risk of early progressive renal function loss in type 1 diabetes: results of a 6-year follow-up

scientific article

IRS1 G972R polymorphism and type 2 diabetes: a paradigm for the difficult ascertainment of the contribution to disease susceptibility of 'low-frequency-low-risk' variants.

scientific article published on 26 June 2009

Identification and importance of brown adipose tissue in adult humans

scientific article

Identification of a locus for maturity-onset diabetes of the young on chromosome 8p23

scientific article published on 01 May 2004

Improved clinical trial enrollment criterion to identify patients with diabetes at risk of end-stage renal disease

scientific article published on 07 April 2017

Increased prevalence of proliferative retinopathy in patients with type 1 diabetes who are deficient in glucose-6-phosphate dehydrogenase

scientific article

Infrequent TRIB3 coding variants and coronary artery disease in type 2 diabetes

scientific article published on 17 July 2015

Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation

scientific article

Intensive Risk Factor Management and Cardiovascular Autonomic Neuropathy in Type 2 Diabetes: The ACCORD Trial

scientific article published on 03 November 2020

Joint effect of insulin signaling genes on all-cause mortality

scientific article

Joint effect of insulin signaling genes on cardiovascular events and on whole body and endothelial insulin resistance

scientific article

Joint effect of insulin signaling genes on insulin secretion and glucose homeostasis.

scientific article

Ketone bodies increase glomerular filtration rate in normal man and in patients with type 1 (insulin-dependent) diabetes mellitus

scientific article published on 01 April 1987

Ketone body kinetics in vivo using simultaneous administration of acetoacetate and 3-hydroxybutyrate labelled with stable isotopes.

scientific article published in January 1990

Leveraging Genetics to Improve Cardiovascular Health in Diabetes: The 2018 Edwin Bierman Award Lecture

scientific article published on 01 March 2019

Lipoprotein compositional abnormalities in type 1 (insulin-dependent) diabetic patients

scientific article published on 01 January 1993

Loss-of-Function Mutation in Thiamine Transporter 1 in a Family With Autosomal Dominant Diabetes

scientific article published on 04 March 2019

Loss-of-Function Mutations in APPL1 in Familial Diabetes Mellitus

scientific journal article

Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes

scientific article

Metabolic control of kidney hemodynamics in normal and insulin-dependent diabetic subjects. Effects of acetoacetic, lactic, and acetic acids

scientific article published on 01 September 1987

Modulation of GLP-1 Levels by a Genetic Variant That Regulates the Cardiovascular Effects of Intensive Glycemic Control in ACCORD.

scientific article published on 28 November 2017

Molecular characterization of a DDEI melting polymorphism at the angiotensin I-converting enzyme (ACE) locus

scientific article published on 01 January 1994

Multigenic control of serum adiponectin levels: evidence for a role of the APM1 gene and a locus on 14q13.

scientific article published on 13 July 2004

Mutation screening of the neurogenin-3 gene in autosomal dominant diabetes.

scientific article

Mutations at the BLK locus linked to maturity onset diabetes of the young and beta-cell dysfunction

scientific article

Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus

scientific article

Myocardial metabolism in type 1 diabetic patients without coronary artery disease

scientific article published on 01 January 1991

PAX4 mutations in Thais with maturity onset diabetes of the young

scientific article published on 10 April 2007

PPARA Polymorphism Influences the Cardiovascular Benefit of Fenofibrate in Type 2 Diabetes: Findings From ACCORD-Lipid

scientific article published on 23 January 2020

Phenotypic characteristics of early-onset autosomal-dominant type 2 diabetes unlinked to known maturity-onset diabetes of the young (MODY) genes.

scientific article published in February 1999

Porcine and human insulin absorption from subcutaneous tissues in normal and insulin-dependent diabetic subjects: a deconvolution-based approach

scientific article published on 01 September 1988

Preventing Early Renal Loss in Diabetes (PERL) Study: A Randomized Double-Blinded Trial of Allopurinol-Rationale, Design, and Baseline Data

scientific article published on 11 June 2019

Protection from retinopathy and other complications in patients with type 1 diabetes of extreme duration: the joslin 50-year medalist study.

scientific article

Putting the genes for type II diabetes on the map

scientific article published on 01 March 2001

Residual insulin production and pancreatic ß-cell turnover after 50 years of diabetes: Joslin Medalist Study. ⬇️

scientific article

SerpinB1 Promotes Pancreatic β Cell Proliferation

scientific article

Serum Resistin, Cardiovascular Disease and All-Cause Mortality in Patients with Type 2 Diabetes ⬇️

scientific article published on June 3, 2013

Serum resistin and glomerular filtration rate in patients with type 2 diabetes

scientific article

Serum resistin and kidney function: a family-based study in non-diabetic, untreated individuals

scientific article (publication date: 2012)

Synergistic effect of angiotensin II type 1 receptor genotype and poor glycaemic control on risk of nephropathy in IDDM

scientific article published on 01 November 1997

Tag polymorphisms at the A20 (TNFAIP3) locus are associated with lower gene expression and increased risk of coronary artery disease in type 2 diabetes

scientific article published on 01 February 2007

The +276 G/T single nucleotide polymorphism of the adiponectin gene is associated with coronary artery disease in type 2 diabetic patients

scientific article published on 01 August 2004

The +276 polymorphism of the APM1 gene, plasma adiponectin concentration, and cardiovascular risk in diabetic men

scientific article (publication date: May 2005)

The 9p21 coronary artery disease locus and kidney dysfunction in patients with Type 2 diabetes mellitus.

scientific article published on 23 May 2012

The ENPP1 Q121 variant predicts major cardiovascular events in high-risk individuals: evidence for interaction with obesity in diabetic patients

scientific article

The IRS1 G972R polymorphism and glomerular filtration rate in patients with type 2 diabetes of European ancestry.

scientific article published on 26 September 2013

The K121Q Polymorphism of the ENPP1/PC-1 Gene Is Associated With Insulin Resistance/Atherogenic Phenotypes, Including Earlier Onset of Type 2 Diabetes and Myocardial Infarction

article

The SH2B1 obesity locus and abnormal glucose homeostasis: lack of evidence for association from a meta-analysis in individuals of European ancestry.

scientific article published on 5 October 2013

The SH2B1 obesity locus is associated with myocardial infarction in diabetic patients and with NO synthase activity in endothelial cells

scientific article published on 19 August 2011

The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes

scientific article

The role of HSP70 on ENPP1 expression and insulin-receptor activation.

scientific article published on 16 December 2008

The role of aldose reductase gene in the susceptibility to diabetic nephropathy in Type II (non-insulin-dependent) diabetes mellitus

scientific article published on 01 January 1999

The type 2 diabetes and insulin-resistance locus near IRS1 is a determinant of HDL cholesterol and triglycerides levels among diabetic subjects

scientific article

Type I insulin-dependent diabetic patients show an impaired renal hemodynamic response to protein intake

scientific article published on 01 January 1988

Uric Acid and Diabetic Nephropathy Risk.

scientific article published on 23 January 2018

Uric acid and risk of diabetic kidney disease

scientific article published on 10 July 2020

Uric acid lowering to prevent kidney function loss in diabetes: the preventing early renal function loss (PERL) allopurinol study

scientific article published on August 2013

Variants in the CD36 gene associate with the metabolic syndrome and high-density lipoprotein cholesterol

scientific article published on 27 February 2008

Variations in adiponectin receptor genes and susceptibility to type 2 diabetes in women: a tagging-single nucleotide polymorphism haplotype analysis

scientific article published on 06 April 2007

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