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List of works by John H. Kehrl

A conserved mechanism of TOR-dependent RCK-mediated mRNA degradation regulates autophagy.

scientific article published on 22 June 2015

A diverged homeobox gene is involved in the proliferation and lineage commitment of human hematopoietic progenitors and highly expressed in acute myelogenous leukemia ⬇️

scientific article published on June 1, 1992

A human homeobox gene, HB24, inhibits development of CD4+ T cells and impairs thymic involution in transgenic mice

scientific article

A novel human homeobox gene distantly related to proboscipedia is expressed in lymphoid and pancreatic tissues

scientific article

A potential role for adrenocorticotropin in regulating human B lymphocyte functions

scientific article published on 01 December 1985

A regulator of G Protein signaling, RGS3, inhibits gonadotropin-releasing hormone (GnRH)-stimulated luteinizing hormone (LH) secretion ⬇️

scientific article published on November 7, 2001

A second human interleukin-2 binding protein that may be a component of high-affinity interleukin-2 receptors

scientific article published in Nature

A vasoactive peptide, endothelin-3, is produced by and specifically binds to primary astrocytes

scientific article

AKT Regulates NLRP3 Inflammasome Activation by Phosphorylating NLRP3 Serine 5

scientific article published on 14 September 2020

Abnormal B-cell responses to chemokines, disturbed plasma cell localization, and distorted immune tissue architecture in Rgs1-/- mice

scientific article published on July 2004

Activated B lymphocytes from human immunodeficiency virus-infected individuals induce virus expression in infected T cells and a promonocytic cell line, U1.

scientific article

Activation and immunoregulation of human B lymphocytes

scientific article published on 01 January 1984

Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction

scientific article

Activation of human B lymphocytes after immunization with pneumococcal polysaccharides

scientific article

Activation of stress-activated protein kinase/c-Jun N-terminal kinase, but not NF-kappaB, by the tumor necrosis factor (TNF) receptor 1 through a TNF receptor-associated factor 2- and germinal center kinase related-dependent pathway

scientific article published in December 1997

Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase

scientific article

Activator of G-Protein Signaling 3-Induced Lysosomal Biogenesis Limits Macrophage Intracellular Bacterial Infection

scientific article published on 14 December 2015

Active suppression of interneuron programs within developing motor neurons revealed by analysis of homeodomain factor HB9.

scientific article published on August 1999

Adaptor proteins CRK and CRKL associate with the serine/threonine protein kinase GCKR promoting GCKR and SAPK activation

scientific article (publication date: February 2000)

Additional 5' exons in the RGS3 locus generate multiple mRNA transcripts, one of which accounts for the origin of human PDZ-RGS3

scientific article (publication date: June 2002)

Alternative cytokines in the immunoregulation of the human B cell cycle

scientific article published on January 1989

An essential role for RGS protein/Gαi2 interactions in B lymphocyte-directed cell migration and trafficking

scientific article

An integrin/MFG-E8 shuttle loads HIV-1 viral-like particles onto follicular dendritic cells in mouse lymph node

scientific article published on 06 December 2019

Analysis of cis-acting elements present in the CD20/B1 antigen promoter ⬇️

scientific article published on December 1, 1991

Analysis of the Bruton's tyrosine kinase gene promoter reveals critical PU.1 and SP1 sites

scientific article published on February 1996

Ascorbic acid transport and distribution in human B lymphocytes

scientific article published on 01 February 1995

Autophagy and inflammasomes

scientific article published on 26 February 2017

Autophagy in macrophages: impacting inflammation and bacterial infection

scientific article published on 09 April 2014

B Lymphocyte-Specific Loss of Ric-8A Results in a Gα Protein Deficit and Severe Humoral Immunodeficiency

scientific article

B cell growth and differentiation factors interact with receptors distinct from the interleukin 2 receptor

scientific article published on 01 July 1986

B cells productively engage soluble antigen-pulsed dendritic cells: visualization of live-cell dynamics of B cell-dendritic cell interactions

scientific article published on 01 December 2005

B lymphocytes exit lymph nodes through cortical lymphatic sinusoids by a mechanism independent of sphingosine-1-phosphate-mediated chemotaxis.

scientific article

Bcl-2 regulates pyroptosis and necroptosis by targeting BH3-like domains in GSDMD and MLKL

scientific article published on 09 December 2019

Bcl-x rather than Bcl-2 mediates CD40-dependent centrocyte survival in the germinal center

scientific article published on August 1996

Beta-agonist-associated reduction in RGS5 expression promotes airway smooth muscle hyper-responsiveness.

scientific article published on 29 January 2011

Biased S1PR1 Signaling in B Cells Subverts Responses to Homeostatic Chemokines, Severely Disorganizing Lymphoid Organ Architecture

scientific article published on 23 September 2019

Binding and functional effects of thyroid stimulating hormone on human immune cells

scientific article published on 01 July 1990

CCL2 deficient mesenchymal stem cells fail to establish long-lasting contact with T cells and no longer ameliorate lupus symptoms

scientific article published on 24 January 2017

CD22 cross-linking generates B-cell antigen receptor-independent signals that activate the JNK/SAPK signaling cascade

scientific article published on August 1999

CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling.

scientific article published on January 1997

Canonical and noncanonical g-protein signaling helps coordinate actin dynamics to promote macrophage phagocytosis of zymosan

scientific article

Cell type- and stage-specific expression of the CD20/B1 antigen correlates with the activity of a diverged octamer DNA motif present in its promoter ⬇️

scientific article published on March 15, 1993

Characterization of GP120 binding to CD4 and an assay that measures ability of sera to inhibit this binding.

scientific article published in December 1988

Characterization of the cellular immune response following in vivo immunization with pneumococcal polysaccharides in man

scientific article published on 01 March 1983

Chemoattract receptor signaling and its role in lymphocyte motility and trafficking

scientific article published on January 2009

Chemoattractant receptor signaling and the control of lymphocyte migration.

scientific article published on January 2006

Cloning of a human homeobox gene that resembles a diverged Drosophila homeobox gene and is expressed in activated lymphocytes

scientific article published on April 1, 1991

Connecting two pathways through Ca 2+ signaling: NLRP3 inflammasome activation induced by a hypermorphic PLCG2 mutation

scientific article

Constitutively active ezrin increases membrane tension, slows migration, and impedes endothelial transmigration of lymphocytes in vivo in mice

scientific article published on 21 November 2011

Contributors

Cutting Edge: Regulator of G protein signaling-1 selectively regulates gut T cell trafficking and colitic potential

scientific article

Cytochrome c Negatively Regulates NLRP3 Inflammasomes

scientific article

Defective chemokine signal integration in leukocytes lacking activator of G protein signaling 3 (AGS3)

scientific article

Differential expression of a novel protein kinase in human B lymphocytes. Preferential localization in the germinal center

scientific article

Differential expression of cell activation markers after stimulation of resting human B lymphocytes

scientific article published on 01 June 1984

Differential sensitivity of human B cell subsets to activation signals delivered by anti-mu antibody and proliferative signals delivered by a monoclonal B cell growth factor

scientific article

Direct activation of human resting T cells by IL 2: the role of an IL 2 receptor distinct from the Tac protein.

scientific article published in September 1987

E-protein-regulated expression of CXCR4 adheres preselection thymocytes to the thymic cortex

scientific article published on 14 June 2019

Effect of tumor necrosis factor alpha on mitogen-activated human B cells

scientific article

Effects of transforming growth factor beta on the functions of natural killer cells: depressed cytolytic activity and blunting of interferon responsiveness

scientific article published on 01 May 1986

Endothelins, peptides with potent vasoactive properties, are produced by human macrophages ⬇️

scientific article published on December 1, 1990

Engagement of the adhesion receptor CD22 triggers a potent stimulatory signal for B cells and blocking CD22/CD22L interactions impairs T-cell proliferation

scientific article published on 01 June 1996

Evidence for a short form of RGS3 preferentially expressed in the human heart

scientific article (publication date: April 2001)

Expression of GTPase-deficient Gialpha2 results in translocation of cytoplasmic RGS4 to the plasma membrane

scientific article

Expression of the HOX-2.3 homeobox gene in human lymphocytes and lymphoid tissues.

scientific article published in July 1991

Further studies of the role of transforming growth factor-beta in human B cell function

scientific article published on September 1989

G-protein-coupled receptor signaling, RGS proteins, and lymphocyte function.

scientific article

G13alpha-mediated PYK2 activation. PYK2 is a mediator of G13alpha -induced serum response element-dependent transcription.

scientific article

GCKR links the Bcr-Abl oncogene and Ras to the stress-activated protein kinase pathway

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Gαi Signaling Promotes Marginal Zone B Cell Development by Enabling Transitional B Cell ADAM10 Expression.

scientific article

Gαi2 Signaling Regulates Inflammasome Priming and Cytokine Production by Biasing Macrophage Phenotype Determination

scientific article published on 25 January 2019

HIV-1 Nef down-modulates C-C and C-X-C chemokine receptors via ubiquitin and ubiquitin-independent mechanism

scientific article published on 29 January 2014

HIV-1 Nef impairs heterotrimeric G-protein signaling by targeting Gα(i2) for degradation through ubiquitination

scientific article

HIV-1 gp120 Impairs B Cell Proliferation by Inducing TGF-β1 Production and FcRL4 Expression

Heterotrimeric G Protein Signaling: Roles in Immune Function and Fine-Tuning by RGS Proteins ⬇️

scientific article published on January 1, 1998

Human B cell activation and cell cycle progression: stimulation with anti-μ andStaphylococcus aureus Cowan strain I ⬇️

scientific article published on 01 February 1984

Human B cell activation, proliferation and differentiation

scientific article

ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation

scientific article published on May 2008

IL-6 and tumor necrosis factor-alpha. Autocrine and paracrine cytokines involved in B cell function

scientific article published on May 1991

IL-7 induces expression and activation of integrin α4β7 promoting naive T-cell homing to the intestinal mucosa

scientific article

Identification of RGS2 and type V adenylyl cyclase interaction sites

scientific article (publication date: 2 May 2003)

Identification of a diverged octamer binding site important in the B cell-specific expression of the CD20 gene

scientific article published on January 1, 1992

Identification, purification, and characterization of antigen-activated and antigen-specific human B lymphocytes

scientific article

Identification, purification, and characterization of antigen-activated and antigen-specific human B lymphocytes

scientific article published on 01 January 1983

Impaired trafficking of Gnai2+/- and Gnai2-/- T lymphocytes: implications for T cell movement within lymph nodes

scientific article published in July 2007

Implications of non-canonical G-protein signaling for the immune system

scientific article

In vitro and in vivo assays of B-lymphocyte migration

scientific article

Induction of nuclear factor-kappa B and the human immunodeficiency virus long terminal repeat by okadaic acid, a specific inhibitor of phosphatases 1 and 2A.

scientific article published on September 1990

Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family

scientific article

Inhibition of human B cell activation by diterpine forskolin: interference with B cell growth factor-induced G1 to S transition of the B cell cycle ⬇️

scientific article published on 01 September 1984

Inhibition of protein phosphatases by okadaic acid induces AP1 in human T cells ⬇️

scientific article published on May 25, 1991

Inhibition of regulator of G protein signaling function by two mutant RGS4 proteins

scientific article published on November 1997

Interleukin 2 receptors on human B cells. Implications for the role of interleukin 2 in human B cell function

scientific article

Intravital Two-Photon Imaging of Lymphocytes Crossing High Endothelial Venules and Cortical Lymphatics in the Inguinal Lymph Node

scientific article

Intravital two-photon imaging of adoptively transferred B lymphocytes in inguinal lymph nodes

scientific article published on January 2009

Involvement of p72syk kinase, p53/56lyn kinase and phosphatidyl inositol-3 kinase in signal transduction via the human B lymphocyte antigen CD22

scientific article

In Vivo F-Actin Filament Organization during Lymphocyte Transendothelial and Interstitial Migration Revealed by Intravital Microscopy

scientific article published on 30 May 2019

Isolation and characterization of TGF-beta 2 and TGF-beta 5 from medium conditioned by Xenopus XTC cells

scientific article published on 01 January 1990

Isolation and characterization of a novel B cell activation gene

scientific article

Key molecules involved in receptor-mediated lymphocyte activation

scientific article

LRRK2 is required for CD38-mediated NAADP-Ca<sup>2+</sup> signaling and the downstream activation of TFEB (transcription factor EB) in immune cells

scientific article published on 27 July 2021

Localization of Gi alpha proteins in the centrosomes and at the midbody: implication for their role in cell division.

scientific article

Long term monitoring of immunoreactive endothelin-1 and endothelin-3 in ventricular cerebrospinal fluid, plasma, and 24-h urine of patients with subarachnoid hemorrhage.

scientific article

Loss of Gαi proteins impairs thymocyte development, disrupts T-cell trafficking, and leads to an expanded population of splenic CD4+PD-1+CXCR5+/- T-cells

scientific article

Lymph node B lymphocyte trafficking is constrained by anatomy and highly dependent upon chemoattractant desensitization.

scientific article published on 28 October 2011

Lymphokine production by B cells from normal and HIV-infected individuals

scientific article

Lymphotoxin is an important T cell-derived growth factor for human B cells

scientific article published on 01 November 1987

Measles virus infection of B lymphocytes permits cellular activation but blocks progression through the cell cycle

scientific article published on November 1987

Millimolar concentrations of ascorbic acid in purified human mononuclear leukocytes. Depletion and reaccumulation.

scientific article published in February 1990

Molecular mechanisms regulating CD19, CD20 and CD22 gene expression

scientific article

MyD88 and Trif target Beclin 1 to trigger autophagy in macrophages.

scientific article published on 04 September 2008

Neutrophil recruitment to lymph nodes limits local humoral response to Staphylococcus aureus

scientific article

Normal Thymocyte Egress, T Cell Trafficking, and CD4+ T Cell Homeostasis Require Interactions between RGS Proteins and Gαi2.

scientific article published on 24 February 2017

Normal autophagic activity in macrophages from mice lacking Gαi3, AGS3, or RGS19.

scientific article

Novel interleukin 2 (IL-2) receptor appears to mediate IL-2-induced activation of natural killer cells

scientific article published on January 1988

Okadaic acid is a potent inducer of AP-1, NF-kappa B, and tumor necrosis factor-alpha in human B lymphocytes

scientific article published in August 1992

Omega-3 free fatty acids suppress macrophage inflammasome activation by inhibiting NF-κB activation and enhancing autophagy

scientific article

PU.1/Pip and basic helix loop helix zipper transcription factors interact with binding sites in the CD20 promoter to help confer lineage- and stage-specific expression of CD20 in B lymphocytes ⬇️

scientific article published on November 15, 1997

PYK2 links G(q)alpha and G(13)alpha signaling to NF-kappa B activation.

scientific article published on 2 July 2001

Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice

scientific article published in September 1999

Pillars Article: production of transforming growth factor β by human T lymphocytes and its potential role in the regulation of T cell growth. J Exp Med. 1986. 163: 1037-1050.

scientific article published in April 2014

Potential role for a regulator of G protein signaling (RGS3) in gonadotropin-releasing hormone (GnRH) stimulated desensitization.

scientific article published on February 1997

Pro- and anti-apoptotic dual functions of the C5a receptor: involvement of regulator of G protein signaling 3 and extracellular signal-regulated kinase

scientific article published on 30 March 2009

Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth

scientific article

Pyk2 amplifies epidermal growth factor and c-Src-induced Stat3 activation

scientific article published on 12 February 2004

RETRACTED: GCK is essential to systemic inflammation and pattern recognition receptor signaling to JNK and p38

scholarly article

RGS family members: GTPase-activating proteins for heterotrimeric G-protein alpha-subunits

scientific article

RGS1 and RGS13 mRNA silencing in a human B lymphoma line enhances responsiveness to chemoattractants and impairs desensitization

scientific article

RGS13 regulates germinal center B lymphocytes responsiveness to CXC chemokine ligand (CXCL)12 and CXCL13

scientific journal article

RGS14 is a centrosomal and nuclear cytoplasmic shuttling protein that traffics to promyelocytic leukemia nuclear bodies following heat shock

scientific journal article

RGS14, a GTPase-activating protein for Gialpha, attenuates Gialpha- and G13alpha-mediated signaling pathways

scientific article

RGS2 regulates signal transduction in olfactory neurons by attenuating activation of adenylyl cyclase III.

scientific article

RGS2: a multifunctional regulator of G-protein signaling

scientific article

RGS3 interacts with 14-3-3 via the N-terminal region distinct from the RGS (regulator of G-protein signalling) domain

scientific article

RGS3 is a GTPase-activating protein for g(ialpha) and g(qalpha) and a potent inhibitor of signaling by GTPase-deficient forms of g(qalpha) and g(11alpha)

scientific article published on 01 October 2000

Recombinant gp120 specifically enhances tumor necrosis factor-alpha production and Ig secretion in B lymphocytes from HIV-infected individuals but not from seronegative donors

scientific article published on 01 November 1991

Regulation of JAK3 expression and activation in human B cells and B cell malignancies ⬇️

scientific article published on December 1, 1995

Regulation of JC virus expression in B lymphocytes

scientific article published on January 1994

Regulation of chemokine-induced lymphocyte migration by RGS proteins

scientific article published in January 2004

Regulation of chemotactic and proadhesive responses to chemoattractant receptors by RGS (regulator of G-protein signaling) family members

scientific article

Regulation of human B-cell activation, proliferation, and differentiation by soluble factors

scientific article published on September 1984

Regulation of immune function by G protein-coupled receptors, trimeric G proteins, and RGS proteins.

scientific article published on 07 October 2009

Regulator of G protein signaling 1 (RGS1) markedly impairs Gi alpha signaling responses of B lymphocytes

scientific article published in February 2000

Regulator of G-protein signaling 3 (RGS3) inhibits Gbeta1gamma 2-induced inositol phosphate production, mitogen-activated protein kinase activation, and Akt activation

scientific article (publication date: 29 June 2001)

Regulator of G-protein signaling 3 isoform 1 (PDZ-RGS3) enhances canonical Wnt signaling and promotes epithelial mesenchymal transition

scientific article

Regulators of G protein signaling exhibit distinct patterns of gene expression and target G protein specificity in human lymphocytes

scientific article (publication date: March 1999)

Regulators of G protein signaling: potential drug targets for controlling cardiovascular and immune function

scientific article published on June 2004

Resistance to inhibitors of cholinesterase (Ric)-8A and Gαi contribute to cytokinesis abscission by controlling vacuolar protein-sorting (Vps)34 activity

scientific article (publication date: 2014)

Retinoic acid mimics transforming growth factor beta in the regulation of human immunodeficiency virus expression in monocytic cells ⬇️

scientific article (publication date: April 1992)

Retraction for Zhong et al. GCK is essential to systemic inflammation and pattern recognition receptor signaling to JNK and p38.

scientific article published on 12 March 2012

Rgs1 and Gnai2 regulate the entrance of B lymphocytes into lymph nodes and B cell motility within lymph node follicles.

scientific article

Rgs13 constrains early B cell responses and limits germinal center sizes

scientific article

Rgs5 targeting leads to chronic low blood pressure and a lean body habitus

scientific article published on 11 February 2008

Ric-8A and Gi alpha recruit LGN, NuMA, and dynein to the cell cortex to help orient the mitotic spindle

scientific article

Role of RGS proteins in regulating the migration of B lymphocytes.

scientific article published on January 2004

Roles for phosphoinositide 3-kinases, Bruton's tyrosine kinase, and Jun kinases in B lymphocyte chemotaxis and homing.

scientific article published on May 2006

SARS-Coronavirus Open Reading Frame-3a drives multimodal necrotic cell death

scholarly article by Yuan Yue published in September 2018

SARS-Coronavirus Open Reading Frame-8b triggers intracellular stress pathways and activates NLRP3 inflammasomes

scientific article published on 05 June 2019

SARS-coronavirus open reading frame-9b suppresses innate immunity by targeting mitochondria and the MAVS/TRAF3/TRAF6 signalosome

scientific article

Selective autoregulation of endothelins in primary astrocyte cultures: endothelin receptor-mediated potentiation of endothelin-1 secretion

article

Selective suppression of an early step in human B cell activation by cyclosporin A ⬇️

scientific article published on September 1, 1983

Sequential requirements for cell cycle progression of resting human B cells after activation by anti-Ig

scientific article published on 01 January 1984

Stable expression of HB24, a diverged human homeobox gene, in T lymphocytes induces genes involved in T cell activation and growth ⬇️

scientific article published on April 25, 1992

TLR4 signaling augments B lymphocyte migration and overcomes the restriction that limits access to germinal center dark zones

scientific article

TNF-mediated activation of the stress-activated protein kinase pathway: TNF receptor-associated factor 2 recruits and activates germinal center kinase related

scientific article (publication date: 15 September 1999)

TOR-dependent post-transcriptional regulation of autophagy

scientific article published on 16 November 2015

TRAF6 and A20 regulate lysine 63-linked ubiquitination of Beclin-1 to control TLR4-induced autophagy

scientific journal article

The G12 family of heterotrimeric G proteins and Rho GTPase mediate Sonic hedgehog signalling

scientific article published on 01 January 2004

The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression

scientific article published on 27 October 2013

The HIV-1 envelope protein gp120 is captured and displayed for B cell recognition by SIGN-R1(+) lymph node macrophages

scientific article

The Use of Intravital Two-Photon and Thick Section Confocal Imaging to Analyze B Lymphocyte Trafficking in Lymph Nodes and Spleen

scientific article published in January 2018

The aorta and heart differentially express RGS (regulators of G-protein signalling) proteins that selectively regulate sphingosine 1-phosphate, angiotensin II and endothelin-1 signalling

scientific article

The clinical use of glucocorticoids

scientific article published on 01 January 1983

The direct effects of interleukin 1, interleukin 2, interferon-alpha, interferon-gamma, B-cell growth factor, and a B-cell differentiation factor on resting and activated human B cells

scientific article

The effects of interleukin-1, interleukin-2, alpha-interferon, and gamma-interferon on human B lymphocytes

scientific article published on 01 January 1984

The influence of sphingosine-1-phosphate receptor signaling on lymphocyte trafficking: how a bioactive lipid mediator grew up from an "immature" vascular maturation factor to a "mature" mediator of lymphocyte behavior and function.

scientific article published on January 2009

The loss of Gnai2 and Gnai3 in B cells eliminates B lymphocyte compartments and leads to a hyper-IgM like syndrome

scientific article

The loss of RGS protein-Gα(i2) interactions results in markedly impaired mouse neutrophil trafficking to inflammatory sites

scientific article

The mitogen-activated protein kinase kinase kinase kinase GCKR positively regulates canonical and noncanonical Wnt signaling in B lymphocytes.

scientific article

The modulation of membrane Ia on human B lymphocytes

scientific article published on 01 May 1985

The role of transcriptional 'futile cycles' in autophagy and microbial pathogenesis

scientific article published on 30 July 2015

The same epitope on CD22 of B lymphocytes mediates the adhesion of erythrocytes, T and B lymphocytes, neutrophils, and monocytes.

scientific article published on June 1993

Toll-like receptor signaling alters the expression of regulator of G protein signaling proteins in dendritic cells: implications for G protein-coupled receptor signaling

scientific article published in May 2004

Tor-dependent post-transcriptional regulation of autophagy: Implications for cancer therapeutics

scientific article published on 16 September 2015

Traf6 and A20 differentially regulate TLR4-induced autophagy by affecting the ubiquitination of Beclin 1.

scientific article

Transactivation of the transforming growth factor beta 1 (TGF-beta 1) gene by human T lymphotropic virus type 1 tax: a potential mechanism for the increased production of TGF-beta 1 in adult T cell leukemia

scientific article

Transforming growth factor beta is an important immunomodulatory protein for human B lymphocytes

scientific article published on 01 December 1986

Transforming growth factor beta suppresses human immunodeficiency virus expression and replication in infected cells of the monocyte/macrophage lineage

scientific article

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro

scientific article published on June 1986

Transforming growth factor-beta is a potent negative regulator of human lymphocytes

scientific article

Transforming growth factor-beta suppresses human B lymphocyte Ig production by inhibiting synthesis and the switch from the membrane form to the secreted form of Ig mRNA

scientific article published on 01 June 1991

Tumor necrosis factor (TNF)-induced germinal center kinase-related (GCKR) and stress-activated protein kinase (SAPK) activation depends upon the E2/E3 complex Ubc13-Uev1A/TNF receptor-associated factor 2 (TRAF2).

scientific article

Tumor necrosis factor alpha functions in an autocrine manner in the induction of human immunodeficiency virus expression

scientific article published on January 1990

Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone

scientific article

Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38. Germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting [...]

scientific article

Tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) in B-lymphocyte function.

scientific article

Two diverged human homeobox genes involved in the differentiation of human hematopoietic progenitors map to chromosome 1, bands q41-42.1

scientific article published on November 1, 1992

Virion incorporation of integrin α4β7 facilitates HIV-1 infection and intestinal homing

scientific article published on May 2017

cDNA cloning of the B cell membrane protein CD22: a mediator of B-B cell interactions

scientific article

β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway

scientific article published on 27 October 2020

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