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List of works by Pirjo Laakkonen

A Novel Anti-HER2 Antibody-Drug Conjugate XMT-1522 for HER2-Positive Breast and Gastric Cancers Resistant to Trastuzumab Emtansine

scientific article published on 10 July 2019

A fragment of the HMGN2 protein homes to the nuclei of tumor cells and tumor endothelial cells in vivo

scientific article

A heparan sulfate-targeted conditionally replicative adenovirus, Ad5.pk7-Delta24, for the treatment of advanced breast cancer.

scientific article

A tumor-homing peptide with a targeting specificity related to lymphatic vessels

scientific article

ARX788, a novel anti-HER2 antibody-drug conjugate, shows anti-tumor effects in preclinical models of trastuzumab emtansine-resistant HER2-positive breast cancer and gastric cancer

scientific article published on 02 January 2020

An optimized isolation of biotinylated cell surface proteins reveals novel players in cancer metastasis

scientific article

Anagrelide for Gastrointestinal Stromal Tumor

scientific article published on 07 December 2018

Antiangiogenic properties of prostate-specific antigen (PSA).

scientific article published on January 2009

Antitumor activity of a homing peptide that targets tumor lymphatics and tumor cells

scientific article

Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

scientific article

Development of peptides specifically modulating the activity of KLK2 and KLK3.

scientific article published on June 2008

Gene expression analyses of primary melanomas reveal CTHRC1 as an important player in melanoma progression.

scientific article published on 23 February 2016

Gene expression changes associated with the anti-angiogenic activity of kallikrein-related peptidase 3 (KLK3) on human umbilical vein endothelial cells

scientific article published on 01 June 2008

Glycodelin reduces breast cancer xenograft growth in vivo.

scientific article

Hepsin regulates TGFβ signaling via fibronectin proteolysis

scientific article published on 4 November 2021

Homing peptides as targeted delivery vehicles.

scientific article published on 26 July 2010

Identification and Characterization of Homing Peptides Using In Vivo Peptide Phage Display.

scientific article published on January 2015

Identification of homing peptides using the in vivo phage display technology.

scientific article

Identification of novel p53 pathway activating small-molecule compounds reveals unexpected similarities with known therapeutic agents

scientific article

In vivo SPECT/CT imaging of human orthotopic ovarian carcinoma xenografts with 111In-labeled monoclonal antibodies

scientific article published on November 2010

Kaposi's sarcoma herpesvirus lytic replication compromises apoptotic response to p53 reactivation in virus-induced lymphomas.

scientific article published on 2 April 2012

Loss of endothelial Tie1 receptor impairs lymphatic vessel development-brief report

scientific article published on 12 November 2009

Lymphatic Microvessels in the Rat Remnant Kidney Model of Renal Fibrosis: Aminopeptidase P and Podoplanin Are Discriminatory Markers for Endothelial Cells of Blood and Lymphatic Vessels

article

Motility of glioblastoma cells is driven by netrin-1 induced gain of stemness

scientific article

Multifunctional porous silicon nanoparticles for cancer theranostics.

scientific article

Nanocrystal targeting in vivo

scientific article

Novel target for peptide-based imaging and treatment of brain tumors

scientific article

Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels

scientific article

Octreotide Conjugates for Tumor Targeting and Imaging

scientific article published on 07 May 2019

PP2A Inhibitor PME-1 Drives Kinase Inhibitor Resistance in Glioma Cells

scientific article published on 26 September 2016

Peptide targeting of tumor lymph vessels

scientific article published on January 2008

Predicting In Vivo Payloads Delivery using a Blood-brain Tumor-barrier in a Dish

scientific article published on 16 April 2019

Prostate-specific membrane antigen expression in the vasculature of primary lung carcinomas associates with faster metastatic dissemination to the brain

scientific article published on 11 May 2020

Reactivation of the p53 pathway as a treatment modality for KSHV-induced lymphomas.

scientific article published on 15 March 2007

Seek & Destroy, use of targeting peptides for cancer detection and drug delivery.

scientific article published in September 2017

Structural characterization and anti-angiogenic properties of prostate-specific antigen isoforms in seminal fluid.

scientific article

Transforming growth factor beta-induced (TGFBI) is an anti-adhesive protein regulating the invasive growth of melanoma cells.

scientific article published on 9 February 2012

Tumor targeting of baculovirus displaying a lymphatic homing peptide

scientific article

Tumor-Targeting Peptides: The Functional Screen of Glioblastoma Homing Peptides to the Target Protein FABP3 (MDGI)

scientific article published on 08 July 2020

Tumour homing peptide-functionalized porous silicon nanovectors for cancer therapy.

scientific article published on 3 September 2013

VEGFR-3 expression is restricted to blood and lymphatic vessels in solid tumors.

scientific article published in June 2008

Vascular Endothelial Growth Factor Receptor 3 Is Involved in Tumor Angiogenesis and Growth

article

Vulnerability of invasive glioblastoma cells to lysosomal membrane destabilization.

scientific article