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List of works by Ronald Vale

A 6-nm ultra-photostable DNA FluoroCube for fluorescence imaging

scientific article published on 16 March 2020

A DNA-Based T Cell Receptor Reveals a Role for Receptor Clustering in Ligand Discrimination.

scientific article

A Ras-like domain in the light intermediate chain bridges the dynein motor to a cargo-binding region

scientific journal article

A composition-dependent molecular clutch between T cell signaling condensates and actin

scientific article published on 3 July 2019

A genome-wide screen identifies conserved protein hubs required for cadherin-mediated cell-cell adhesion

scientific article published on January 2014

A lever-arm rotation drives motility of the minus-end-directed kinesin Ncd.

scientific article

A new cap for kinetochore fibre minus ends

scientific article published on 13 November 2011

A protein-tagging system for signal amplification in gene expression and fluorescence imaging

scientific article

A standardized kinesin nomenclature

scientific article

A tribute to Shinya Inoue and innovation in light microscopy

scientific article published on April 2004

A whole genome RNAi screen of Drosophila S2 cell spreading performed using automated computational image analysis ⬇️

scientific article published on November 1, 2010

Accelerating scientific publication in biology

scientific article

Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes

scientific article

Advanced methods of microscope control using μManager software

scientific article published on January 2014

Allosteric communication in the dynein motor domain

scientific article

Altered actin centripetal retrograde flow in physically restricted immunological synapses

scientific article (publication date: 2010)

An acquisition and analysis pipeline for scanning angle interference microscopy

scientific article published on October 2016

Architectures of Lipid Transport Systems for the Bacterial Outer Membrane

scientific article published on April 2017

Architectures of a lipid transport systems for the bacterial outer membrane

Assembly and activation of dynein-dynactin by the cargo adaptor protein Hook3

scientific article

Augmin promotes meiotic spindle formation and bipolarity in Xenopus egg extracts ⬇️

scientific article published on August 15, 2011

Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle

scientific article published on 28 April 2008

Autoinhibition regulates the motility of the C. elegans intraflagellar transport motor OSM-3

scientific article

Autophagy genes function sequentially to promote apoptotic cell corpse degradation in the engulfing cell ⬇️

scientific article published on March 26, 2012

Autophagy genes promote apoptotic cell corpse clearance

article

Biophysical mechanism of T-cell receptor triggering in a reconstituted system

scientific article

Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2.

scientific article

CD47 Ligation Repositions the Inhibitory Receptor SIRPA to Suppress Integrin Activation and Phagocytosis

scientific article published on 04 August 2020

CRACR2a is a calcium-activated dynein adaptor protein that regulates endocytic traffic

scientific article published on 27 February 2019

Cell Sorting in Hydra vulgaris Arises from Differing Capacities for Epithelialization between Cell Types

scientific article published on 06 August 2020

Cell cycle-dependent dynamics and regulation of mitotic kinesins in Drosophila S2 cells

scientific article

Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia.

scientific article

Chimeric antigen receptors that trigger phagocytosis.

scientific article published on 4 June 2018

Closing of the Nucleotide Pocket of Kinesin-Family Motors upon Binding to Microtubules ⬇️

scientific article published on May 2, 2003

Clustering of a kinesin-14 motor enables processive retrograde microtubule-based transport in plants

scientific article

Communication between the AAA+ ring and microtubule-binding domain of dynein

scientific article

Conversion of Unc104/KIF1A kinesin into a processive motor after dimerization

scientific article

Cortical dynein controls microtubule dynamics to generate pulling forces that position microtubule asters

scientific article

Coupled Membrane Lipid Miscibility and Phosphotyrosine-Driven Protein Condensation Phase Transitions

scientific article published on 24 September 2020

Coupling of ATPase activity, microtubule binding, and mechanics in the dynein motor domain

scientific article published on 31 May 2019

Creating opportunities for science PhDs to pursue careers in high school education

scientific article

Crystal structure of the dynein motor domain

scientific article

Cytoplasmic dynein crosslinks and slides anti-parallel microtubules using its two motor domains

scientific article published on 03 September 2013

De novo mutations in KIF1A cause progressive encephalopathy and brain atrophy

scientific article published on May 2015

Determinants of myosin II cortical localization during cytokinesis

scientific article published on 10 June 2010

Direct detection of SARS-CoV-2 RNA using high-contrast pH-sensitive dyes

scientific article published on 01 September 2021

Disease-associated mutations in human BICD2 hyperactivate motility of dynein-dynactin

scientific article

Distinct conformations of the kinesin Unc104 neck regulate a monomer to dimer motor transition

scientific article

Distinct mechanisms govern the localisation of Drosophila CLIP-190 to unattached kinetochores and microtubule plus-ends.

scientific article published in August 2005

Distinct pathways control recruitment and maintenance of myosin II at the cleavage furrow during cytokinesis.

scientific article

Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle

scientific article

Drosophila RhoGEF2 associates with microtubule plus ends in an EB1-dependent manner

scientific article

Drosophila pod-1 crosslinks both actin and microtubules and controls the targeting of axons

scientific article published in August 2003

Dynamics of Translation of Single mRNA Molecules In Vivo

scientific article published on May 2016

Dynamics of myosin, microtubules, and Kinesin-6 at the cortex during cytokinesis in Drosophila S2 cells.

scientific article published on 31 August 2009

EPR Spectroscopy Shows a Microtubule-Dependent Conformational Change in the Kinesin Switch 1 Domain ⬇️

scientific article published on May 1, 2003

Electron cryotomography of intact motile cilia defines the basal body to axoneme transition

scientific article published on 01 January 2020

Erratum

Evaluating how we evaluate

scientific article

Force-induced bidirectional stepping of cytoplasmic dynein

scientific article

Functional genomic screen reveals genes involved in lipid-droplet formation and utilization

scientific article

Functionally distinct kinesin-13 family members cooperate to regulate microtubule dynamics during interphase.

scientific article published on 20 February 2005

Genes involved in centrosome-independent mitotic spindle assembly in Drosophila S2 cells

scientific article

Genes required for mitotic spindle assembly in Drosophila S2 cells

scientific article

Graduate education. Interdisciplinary graduate training in teaching labs

scientific article published on December 2012

High accuracy measurements of nanometer-scale distances between fluorophores at the single-molecule level

HkRP3 is a microtubule-binding protein regulating lytic granule clustering and NK cell killing

scientific article published on 11 March 2015

How Dynein Moves Along Microtubules

scientific article

How kinesin waits between steps

scientific article

How lucky can one be? A perspective from a young scientist at the right place at the right time ⬇️

scientific article published on October 1, 2012

Imaging T-cell receptor activation reveals accumulation of tyrosine-phosphorylated CD3ζ in the endosomal compartment.

scientific article

Impact of New Camera Technologies on Discoveries in Cell Biology

scientific article published on August 2016

In vitro membrane reconstitution of the T-cell receptor proximal signaling network

scientific article

In vitro reconstitution of T cell receptor-mediated segregation of the CD45 phosphatase.

scientific article published on 17 October 2017

Induction of focal adhesions and motility in Drosophila S2 cells

scientific article

Insights into centriole geometry revealed by cryotomography of doublet and triplet centrioles

scientific article published on 06 August 2018

Intramolecular strain coordinates kinesin stepping behavior along microtubules

scientific article published on September 2008

Introducing simulated cellular architecture to the quantitative analysis of fluorescent microscopy

scientific article

Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding

article

It's a wonderful life: a career as an academic scientist

scientific article

Keep Your Eyes on the Prize

scientific article published on 02 April 2019

Kinesin motors and microtubule-based organelle transport in Dictyostelium discoideum

scientific article

Kinesin walks hand-over-hand

scientific article

Kinesin-73 Is a Processive Motor That Localizes to Rab5-containing Organelles ⬇️

scientific article published on December 18, 2010

Length control of the metaphase spindle

scientific article published on November 2005

Making microtubules and mitotic spindles in cells without functional centrosomes

scientific article published in March 2006

Making more microtubules by severing: a common theme of noncentrosomal microtubule arrays?

scientific article published on December 2006

Mechanism of prion propagation: amyloid growth occurs by monomer addition

scientific article

Mechanism of transport of IFT particles in C. elegans cilia by the concerted action of kinesin-II and OSM-3 motors

scientific article

Mechanisms for focusing mitotic spindle poles by minus end-directed motor proteins

scientific article published on October 2005

Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells

scientific article

Micro-Magellan: open-source, sample-adaptive, acquisition software for optical microscopy.

scientific article published on September 2013

Microscopes for fluorimeters: the era of single molecule measurements

scientific article

Microtubule nucleation at the centrosome and beyond

scientific article published on August 2015

Mitochondrial positioning in fission yeast is driven by association with dynamic microtubules and mitotic spindle poles

scientific article

Mob4 plays a role in spindle focusing in Drosophila S2 cells

scientific article

Molecular dissection of the roles of nucleotide binding and hydrolysis in dynein's AAA domains in Saccharomyces cerevisiae

scientific article

Molecular dissection of the roles of nucleotide binding and hydrolysis in dynein's AAA domains in Saccharomyces cerevisiae

scholarly article

Molecular requirements for actin-based lamella formation in Drosophila S2 cells

scientific article

Molecular signatures of cell migration in C. elegans Q neuroblasts

scientific article published on April 2009

Myosin V motor proteins: marching stepwise towards a mechanism

scientific article published on November 2003

Nanometer-accuracy distance measurements between fluorophores at the single-molecule level

scientific article published on 15 February 2019

New cytoskeletal liaisons

scientific article published in Nature

Not just Salk

scientific article published in September 2017

Patronin regulates the microtubule network by protecting microtubule minus ends.

scientific article published on October 2010

Phase separation of signaling molecules promotes T cell receptor signal transduction

scientific article published on 7 April 2016

Phosphorylation of β-Tubulin by the Down Syndrome Kinase, Minibrain/DYRK1a, Regulates Microtubule Dynamics and Dendrite Morphogenesis

scientific article

Polarized myosin produces unequal-size daughters during asymmetric cell division.

scientific article

Preface: the role of reconstitution in cytoskeleton research.

scientific article published in January 2014

Preprints for the life sciences ⬇️

scientific article

Priority of discovery in the life sciences

scientific article

Publish peer reviews

scientific article published in Nature

Publisher Correction: The cytoplasmic dynein transport machinery and its many cargoes

scientific article published on 01 July 2018

Quantification and modeling of tripartite CD2-, CD58FC chimera (alefacept)-, and CD16-mediated cell adhesion

scientific article published on 2 October 2007

RNA phase transitions in repeat expansion disorders

scientific article

Reconstitution of TCR Signaling Using Supported Lipid Bilayers

scientific article published in January 2017

Regulation of mRNA translation during mitosis

scientific article

Regulation of microtubule minus-end dynamics by CAMSAPs and Patronin

scientific article published on 26 March 2014

Regulation of microtubule motors by tubulin isotypes and post-translational modifications

scientific article published on 16 March 2014

Regulation of the processivity and intracellular localization of Saccharomyces cerevisiae dynein by dynactin

scientific article

Regulators of the cytoplasmic dynein motor

scientific article

Regulatory ATPase sites of cytoplasmic dynein affect processivity and force generation

scientific article published on 23 July 2008

Rewired signaling network in T cells expressing the chimeric antigen receptor (CAR)

scientific article published on 09 July 2020

Role of phosphatidylinositol(4,5)bisphosphate organization in membrane transport by the Unc104 kinesin motor

scientific article

Single-molecule analysis of dynein processivity and stepping behavior

scientific article

Single-molecule imaging of fluorescent proteins

scientific article

Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells

scientific article

Single-molecule observations of neck linker conformational changes in the kinesin motor protein.

scientific article published on October 2006

Spatial control of Draper receptor signaling initiates apoptotic cell engulfment.

scientific article published on 23 August 2018

Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochore

scientific article

Structural basis of microtubule plus end tracking by XMAP215, CLIP-170, and EB1

scientific article

Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin

scientific article

Structural determinants for EB1-mediated recruitment of APC and spectraplakins to the microtubule plus end.

scientific article

Structure and Functional Role of Dynein's Microtubule-Binding Domain

scientific article

Structure of the radial spoke head and insights into its role in mechanoregulation of ciliary beating

scientific article published on 14 December 2020

T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition.

scientific article

Ten simple rules for considering preprints

Ten simple rules to consider regarding preprint submission

scientific article (publication date: 4 May 2017)

The Arf GAP CNT-2 Regulates the Apoptotic Fate in C. elegans Asymmetric Neuroblast Divisions ⬇️

scientific article published on May 19, 2011

The Drosophila homologue of the hereditary spastic paraplegia protein, spastin, severs and disassembles microtubules

scientific article

The Khd1 protein, which has three KH RNA-binding motifs, is required for proper localization of ASH1 mRNA in yeast

scientific article

The affinity of the dynein microtubule-binding domain is modulated by the conformation of its coiled-coil stalk

scientific article

The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells

scientific article

The biological sciences in India: aiming high for the future

scientific article published on February 2009

The coreceptor CD2 uses plasma membrane microdomains to transduce signals in T cells

scientific article published on 27 April 2009

The cytoplasmic dynein transport machinery and its many cargoes.

scientific article published on 16 April 2018

The lipid binding pleckstrin homology domain in UNC-104 kinesin is necessary for synaptic vesicle transport in Caenorhabditis elegans

scientific article

The mechanism of dynein motility: insight from crystal structures of the motor domain

scientific article published on 28 October 2011

The molecular motor toolbox for intracellular transport

scientific article (publication date: 21 February 2003)

The roles of microtubule-based motor proteins in mitosis: comprehensive RNAi analysis in the Drosophila S2 cell line

scientific article

The value of asking questions

scientific article

Total Internal Reflection Fluorescence Microscopy

scientific article published on 01 September 2015

Tracking Movements of the Microtubule Motors Kinesin and Dynein Using Total Internal Reflection Fluorescence Microscopy

scientific article published in September 2015

Tuning the Antigen Density Requirement for CAR T Cell Activity

scientific article published on 19 March 2020

Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase

scientific article (publication date: 22 January 2004)

Unbiased selection of localization elements reveals cis-acting determinants of mRNA bud localization in Saccharomyces cerevisiae

scientific article published on 2 December 2005

Use of RNA interference in Drosophila S2 cells to identify host pathways controlling compartmentalization of an intracellular pathogen

scientific article

Walking the walk: how kinesin and dynein coordinate their steps

scientific article published on 27 January 2009

Young Leaders for Biology in India ⬇️

scientific article published on September 17, 2010

iBioChina and iBiology: spreading scientific knowledge together

scientific article published in October 2015

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