Search filters

List of works by Will Fischer

A multiple-alignment based primer design algorithm for genetically highly variable DNA targets

scientific article

Comparative analysis of hepatitis C virus phylogenies from coding and non-coding regions: the 5' untranslated region (UTR) fails to classify subtypes

scientific article (publication date: 14 December 2006)

Coping with viral diversity in HIV vaccine design: a response to Nickle et al.

scientific article published on January 2008

Correction: Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection

scientific article published on 14 September 2017

Designing and testing broadly-protective filoviral vaccines optimized for cytotoxic T-lymphocyte epitope coverage

scientific article

Distinct evolutionary pressures underlie diversity in simian immunodeficiency virus and human immunodeficiency virus lineages

scientific article

Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells

scientific article published on 31 May 2016

Epitope-specific CD8+ T lymphocytes cross-recognize mutant simian immunodeficiency virus (SIV) sequences but fail to contain very early evolution and eventual fixation of epitope escape mutations during SIV infection

scientific article

Erratum for Smith et al., Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells

scientific article published on 12 July 2016

Evidence from small-subunit ribosomal RNA sequences for a fungal origin of Microsporidia.

scientific article

Expanded breadth of the T-cell response to mosaic human immunodeficiency virus type 1 envelope DNA vaccination

scientific article published on 24 December 2008

GenBank: current status and future directions

scientific article

Genotype 1 and global hepatitis C T-cell vaccines designed to optimize coverage of genetic diversity.

scientific article published on 6 January 2010

Hepatitis C genotype 1 mosaic vaccines are immunogenic in mice and induce stronger T-cell responses than natural strains

scientific article published on 5 December 2012

Human APOBEC3 induced mutation of human immunodeficiency virus type-1 contributes to adaptation and evolution in natural infection

scientific article

Human leukocyte antigen-associated sequence polymorphisms in hepatitis C virus reveal reproducible immune responses and constraints on viral evolution

scientific article published in August 2007

Immunological and virological mechanisms of vaccine-mediated protection against SIV and HIV.

scientific article published on 18 December 2013

Increased sequence diversity coverage improves detection of HIV-specific T cell responses

scientific article published in November 2007

Integrated sequence and immunology filovirus database at Los Alamos

scientific article published on 21 April 2016

Molecular evidence for the early evolution of photosynthesis.

scientific article published on September 2000

Mosaic HIV-1 vaccines expand the breadth and depth of cellular immune responses in rhesus monkeys

scientific article

Mosaic vaccines elicit CD8+ T lymphocyte responses that confer enhanced immune coverage of diverse HIV strains in monkeys

scientific article published on 21 February 2010

P09-21 LB. Deep sequencing of HIV-1 from acute infection: low initial diversity, and rapid but variable CTL escape

article

P16-13. A greater breadth of HIV-1-specific T cell responses detected using mosaic peptides compare to consensus peptides.

scientific article published on 22 October 2009

P20-21 LB. Gene-to-gene differences in evolutionary rate between HIV-1 and natural SIV from sooty mangabeys: implications for vaccine tests in non-human primates.

scientific article published on 22 October 2009

Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants

scientific article published on 24 December 2006

Protection against a mixed SHIV challenge by a broadly neutralizing antibody cocktail.

scientific article published on September 2017

Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection

scientific article published on 31 July 2017

Sparse coding of pathology slides compared to transfer learning with deep neural networks

scholarly article by Will Fischer et al published 21 December 2018 in BMC Bioinformatics

Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2

scientific article published on 01 May 2020

Structural Transition and Antibody Binding of EBOV GP and ZIKV E Proteins from Pre-Fusion to Fusion-Initiation State.

scientific article

T cell-based strategies for HIV-1 vaccines

scientific article published on 25 October 2019

Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing

scientific article

Vaccine Advances against Venezuelan, Eastern, and Western Equine Encephalitis Viruses

scientific article published on 03 June 2020

Web-based design and evaluation of T-cell vaccine candidates

scientific article published on 29 May 2008