List of works - Ernst R Tamm

Abnormal vessel formation in the choroid of mice lacking tissue inhibitor of metalloprotease-3.

scientific article

Age changes in rhesus monkey ciliary muscle: light and electron microscopy

scientific article published on 01 December 1988

Age-related changes of the ciliary muscle in comparison with changes induced by treatment with prostaglandin F2 alpha. An ultrastructural study in rhesus and cynomolgus monkeys.

scientific article published on February 1990

Age-related loss of ciliary muscle mobility in the rhesus monkey. Role of the choroid.

scientific article published in June 1992

Age-related loss of morphologic responses to pilocarpine in rhesus monkey ciliary muscle

scientific article published on 01 November 1988

AlphaB-crystallin in lens development and muscle integrity: a gene knockout approach ⬇️

scientific article published on November 1, 2001

Ambiguous role of glucocorticoids on survival of retinal neurons.

scientific article published on January 2014

Bone morphogenetic protein-7 is an antagonist of transforming growth factor-beta2 in human trabecular meshwork cells.

scientific article published in February 2007

Carbonic anhydrase activity is increased in retinal pigmented epithelium and choriocapillaris of RCS rats

scientific article published on 01 April 1996

Cell cultures of human ciliary muscle: growth, ultrastructural and immunocytochemical characteristics

scientific article published on 01 September 1991

Characterization of muscarinic receptor involvement in human ciliary muscle cell function

scientific article published on 01 January 1994

Characterization of the mouse Myoc/Tigr gene.

scientific article published on April 1998

Chromatin-remodeling factor Brg1 is required for Schwann cell differentiation and myelination

scientific article

Connective tissue growth factor causes glaucoma by modifying the actin cytoskeleton of the trabecular meshwork.

scientific article

Connective tissue growth factor induces extracellular matrix deposition in human trabecular meshwork cells.

scientific article published on 7 February 2009

Connective tissue growth factor modulates podocyte actin cytoskeleton and extracellular matrix synthesis and is induced in podocytes upon injury

scientific article published on 04 August 2011

Constitutive overexpression of Norrin activates Wnt/β-catenin and endothelin-2 signaling to protect photoreceptors from light damage

scientific article

Contractile cells in the human scleral spur ⬇️

scientific article published on April 1, 1992

Correction: Identification of Pax6-Dependent Gene Regulatory Networks in the Mouse Lens.

scientific article published on 26 March 2009

Correction: Progressive Retinal Degeneration and Glial Activation in the CLN6nclf Mouse Model of Neuronal Ceroid Lipofuscinosis: A Beneficial Effect of DHA and Curcumin Supplementation.

scientific article published on 9 October 2013

Cre recombinase expression or topical tamoxifen treatment do not affect retinal structure and function, neuronal vulnerability or glial reactivity in the mouse eye.

scientific article published on 26 March 2016

Current aspects of aqueous humor dynamics and glaucoma

scientific article published on 27 February 2009

Deletion of ocular transforming growth factor β signaling mimics essential characteristics of diabetic retinopathy

scientific article published on 7 April 2015

Development of the human eye ⬇️

scientific article published on 01 September 2012

Different cell populations in bovine trabecular meshwork: An ultrastructural and immunocytochemical study ⬇️

scientific article published on June 1, 1991

Different collagen types define two types of idiopathic epiretinal membranes

scientific article published on 12 April 2011

Differential angiogenic properties of lithium chloride in vitro and in vivo.

scientific article

Disruption of the retinitis pigmentosa 28 gene Fam161a in mice affects photoreceptor ciliary structure and leads to progressive retinal degeneration

scientific journal article

Donor corneoscleral buttons: a new source of trabecular meshwork for research.

scientific article published in December 2003

Ectopic norrin induces growth of ocular capillaries and restores normal retinal angiogenesis in Norrie disease mutant mice.

scientific article

Effect of heparin II domain of fibronectin on aqueous outflow in cultured anterior segments of human eyes.

scientific article published in November 2003

Effects of elevated intraocular pressure on outflow facility and TIGR/MYOC expression in perfused human anterior segments.

scientific article

Effects of transforming growth factor-beta1 and basic fibroblast growth factor on proliferation of cell cultures derived from human vestibular nerve schwannoma.

scientific article published in June 1998

Electrogenic sodium-bicarbonate cotransport in human ciliary muscle cells.

scientific article published on February 1992

Epithelial-mesenchymal transition of the retinal pigment epithelium causes choriocapillaris atrophy

scientific article published on 2 July 2016

Establishment of myelinating Schwann cells and barrier integrity between central and peripheral nervous systems depend on Sox10.

scientific article published on 15 February 2012

Focus on Molecules: Myocilin/TIGR.

scientific article published on 28 July 2005

Focus on molecules: Norrin

scientific article published on 30 June 2011

Formation of fenestrae in murine liver sinusoids depends on plasmalemma vesicle-associated protein and is required for lipoprotein passage.

scientific article

Gap junctions are found between iris sphincter smooth muscle cells but not in the ciliary muscle of human and monkey eyes

scientific article published on 01 August 1996

Gene expression profiling of TGFbeta2- and/or BMP7-treated trabecular meshwork cells: Identification of Smad7 as a critical inhibitor of TGF-beta2 signaling.

scientific article published on 18 January 2009

Gene targeting reveals a widespread role for the high-mobility-group transcription factor Sox11 in tissue remodeling

scientific journal article

Genetic dissection of Pax6 dosage requirements in the developing mouse eye

scientific article published on 29 June 2005

Heterozygote Wdr36-deficient mice do not develop glaucoma

scientific article published on 26 September 2014

Heterozygous modulation of TGF-β signaling does not influence Müller glia cell reactivity or proliferation following NMDA-induced damage

scientific article published on 28 July 2015

Identification of adult stem cells in Schwalbe's line region of the primate eye.

scientific article

Identification of pax6-dependent gene regulatory networks in the mouse lens

scientific article

Immunohistochemical characterization of the 'intimal proliferation' phenomenon in Sneddon's syndrome and essential thrombocythaemia.

scientific article

Immunohistochemical localization of neuropeptides in the human ciliary ganglion

scientific article published on 01 May 1995

Inactivation of the murine X-linked juvenile retinoschisis gene, Rs1h, suggests a role of retinoschisin in retinal cell layer organization and synaptic structure

scientific article

Increase in types IV and VI collagen in cherry haemangiomas

scientific article published on 01 January 1992

Increased expression of olfactomedin-1 and myocilin in podocytes during puromycin aminonucleoside nephrosis.

scientific article

Innervation of myofibroblast-like scleral spur cells in human monkey eyes

scientific article published on 01 July 1995

Intraocular Pressure and the Mechanisms Involved in Resistance of the Aqueous Humor Flow in the Trabecular Meshwork Outflow Pathways.

scientific article published on 09 July 2015

Kidney podocytes as specific targets for cyclo(RGDfC)-modified nanoparticles.

scientific article published on 8 August 2012

Lack of WDR36 leads to preimplantation embryonic lethality in mice and delays the formation of small subunit ribosomal RNA in human cells in vitro.

scientific article

Lack of endothelial diaphragms in fenestrae and caveolae of mutant Plvap-deficient mice

scientific article published on 11 July 2012

Laminin Promotes Differentiation, Adhesion and Proliferation of Cell Cultures Derived from Human Acoustic Nerve Schwannoma

article

Latanoprost induces matrix metalloproteinase-1 expression in human nonpigmented ciliary epithelial cells through a cyclooxygenase-2-dependent mechanism.

scientific article

Localization of myocilin/trabecular meshwork--inducible glucocorticoid response protein in the human eye

scientific article published on 01 March 2000

MicroRNAs are essential for differentiation of the retinal pigmented epithelium and maturation of adjacent photoreceptors

scientific article published on 10 June 2015

Modulation of myocilin/TIGR expression in human trabecular meshwork.

scientific article published on October 1999

Morphological study of the anterior segment of cynomolgus monkey eyes following treatment with prostaglandin F2 alpha

scientific article published on 01 November 1988

Multivalent nanoparticles bind the retinal and choroidal vasculature.

scientific article published on 19 October 2015

Mutated olfactomedin 1 in the interphotoreceptor matrix of the mouse retina causes functional deficits and vulnerability to light damage

scientific article published on 27 October 2016

Myocilin and glaucoma: facts and ideas.

scientific article

Myocilin in the trabecular meshwork of eyes with primary open-angle glaucoma

scientific article published on 07 August 2009

Myocilin is expressed in the glomerulus of the kidney and induced in mesangioproliferative glomerulonephritis

scientific journal article

Myocilin modulates programmed cell death during retinal development

scientific article published on 15 May 2014

Müller cells and microglia of the mouse eye react throughout the entire retina in response to the procedure of an intravitreal injection

scientific article published on 01 January 2014

N-methyl-D-aspartate (NMDA)-mediated excitotoxic damage: a mouse model of acute retinal ganglion cell damage

scientific article published on 01 January 2013

Nerve cells in the human ciliary muscle: ultrastructural and immunocytochemical characterization

scientific article published on 01 February 1995

Nerve endings with structural characteristics of mechanoreceptors in the human scleral spur

scientific article published on 01 March 1994

Neuroprotection in glaucoma

scientific article published on 28 June 2013

Nitrergic nerve cells in the primate ciliary muscle are only present in species with a fovea centralis

scientific article published on 01 January 1997

Norrin Protects Retinal Ganglion Cells from Excitotoxic Damage via the Induction of Leukemia Inhibitory Factor

scientific article published on 23 January 2020

Norrin mediates angiogenic properties via the induction of insulin-like growth factor-1.

scientific article

Norrin mediates neuroprotective effects on retinal ganglion cells via activation of the Wnt/beta-catenin signaling pathway and the induction of neuroprotective growth factors in Muller cells.

scientific article

Norrin promotes vascular regrowth after oxygen-induced retinal vessel loss and suppresses retinopathy in mice.

scientific article

Norrin: molecular and functional properties of an angiogenic and neuroprotective growth factor.

scientific article published on 21 February 2012

Ocular adenovirus gene transfer varies in efficiency and inflammatory response.

scientific article published on June 1996

Omega -crystallin of the scallop lens. A dimeric aldehyde dehydrogenase class 1/2 enzyme-crystallin.

scientific article

On the use of immortalized ocular cell lines in vision research: the unfortunate story of RGC-5.

scientific article published on 7 September 2013

Optineurin associates with the podocyte Golgi complex to maintain its structure

scientific article

Overexpression and properties of wild-type and Tyr437His mutated myocilin in the eyes of transgenic mice

scientific article published in January 2005

Pax6 dosage requirements in iris and ciliary body differentiation

scientific article published on 27 June 2009

Pax6 heterozygous eyes show defects in chamber angle differentiation that are associated with a wide spectrum of other anterior eye segment abnormalities

scientific article published on 01 October 2002

Perfusion with the Olfactomedin Domain of Myocilin Does Not Affect Outflow Facility ⬇️

scientific article published on May 1, 2003

Posterior attachment of ciliary muscle in young, accommodating old, presbyopic monkeys

scientific article published on 01 April 1991

Programmed cell death during retinal development of the mouse eye.

scientific article published on January 2014

Progressive retinal degeneration and glial activation in the CLN6 (nclf) mouse model of neuronal ceroid lipofuscinosis: a beneficial effect of DHA and curcumin supplementation

scientific article

Reduced expression of Pax6 in lens and cornea of mutant mice leads to failure of chamber angle development and juvenile glaucoma.

scientific article published on 10 June 2010

Role of bestrophin-1 in store-operated calcium entry in retinal pigment epithelium.

scientific article

Rybp, a polycomb complex-associated protein, is required for mouse eye development

scientific article

Secreted glycoprotein myocilin is a component of the myelin sheath in peripheral nerves

scientific journal article

Short-term psychosocial stress protects photoreceptors from damage via corticosterone-mediated activation of the AKT pathway.

scientific article

Single-cell contraction assay for human ciliary muscle cells. Effect of carbachol

scientific article published on 01 April 1993

Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage

scientific article published on 10 May 2010

Sox10 is required for Schwann-cell homeostasis and myelin maintenance in the adult peripheral nerve

scientific article published on 12 April 2011

Species differences in choroidal vasodilative innervation: evidence for specific intrinsic nitrergic and VIP-positive neurons in the human eye

scientific article published on 01 February 1994

Status and perspectives of neuroprotective therapies in glaucoma: the European Glaucoma Society White Paper

scientific article

Superior cervical ganglionectomy in monkeys: effects on refraction and intraocular pressure

scientific article published on 01 May 1999

Superior cervical ganglionectomy in monkeys: light and electron microscopy of the anterior eye segment

scientific article published on 01 July 1997

Synthesis of extracellular matrix components by human ciliary muscle cells in culture

scientific article published on April 1, 1992

TGF-β signaling protects retinal neurons from programmed cell death during the development of the mammalian eye.

scientific article

Tamoxifen-Containing Eye Drops Successfully Trigger Cre-Mediated Recombination in the Entire Eye

scientific article published on 01 January 2016

Tg(Grm1) transgenic mice: a murine model that mimics spontaneous uveal melanoma in humans?

scientific article

The aqueous humor outflow pathways in glaucoma: A unifying concept of disease mechanisms and causative treatment

scientific article published on 06 May 2015

The class III POU domain protein Brn-1 can fully replace the related Oct-6 during schwann cell development and myelination

scientific journal article

The different functions of Norrin.

scientific article published on January 2012

The effect of temperature on gene silencing by siRNAs: implications for silencing in the anterior chamber of the eye.

scientific article

The expression of myocilin during murine eye development.

scientific article published on 29 January 2004

The origin of extrinsic nitrergic axons supplying the human eye.

scientific article published in March 2005

The presence and properties of myocilin in the aqueous humor

scientific article published on 01 April 2001

The prostaglandin f2α analog fluprostenol attenuates the fibrotic effects of connective tissue growth factor on human trabecular meshwork cells.

scientific article

The regulation of connective tissue growth factor expression influences the viability of human trabecular meshwork cells.

scientific article published on 20 February 2015

The role of Müller glia and microglia in glaucoma ⬇️

scientific article published on June 19, 2013

The role of TGF-β in the pathogenesis of primary open-angle glaucoma.

scientific article

The role of bestrophin-1 in intracellular Ca(2+) signaling

scientific article published on January 2014

The role of plasmalemma vesicle-associated protein (PLVAP) in endothelial cells of Schlemm's canal and ocular capillaries

scientific article published on 09 October 2012

The trabecular meshwork outflow pathways: structural and functional aspects.

scientific article published on 23 February 2009

The transcription factors Sox10 and Myrf define an essential regulatory network module in differentiating oligodendrocytes

scientific article

Thrombospondin-1 in the trabecular meshwork: localization in normal and glaucomatous eyes, and induction by TGF-beta1 and dexamethasone in vitro.

scientific article published in November 2004

Transforming growth factor-beta 1 induces alpha-smooth muscle-actin expression in cultured human and monkey trabecular meshwork

scientific article published on 01 April 1996

Transgenic lysyl oxidase homolog 1 overexpression in the mouse eye results in the formation and release of protein aggregates

scientific article published on 03 November 2018

Viscocanalostomy in rhesus monkeys.

scientific article

Visualization of hyaluronic acid in the anterior segment of rabbit and monkey eyes

scientific article published on 01 July 1990

What is the nature of the RGC-5 cell line?

scientific article published on January 2014

[Development of the iridocorneal angle and congenital glaucoma]

scientific article published on 01 July 2011

[Electron microscopy and immunohistochemical studies of the intraocular pressure lowering effect of prostaglandin F2 alpha]

scientific article published on 01 January 1990

[Functional morphology of the outflow pathways of aqueous humor and their changes in open angle glaucoma].

scientific article

[Immunocytochemical and ultrastructural studies of human scleral spur. Characterization of a contractile cell population]

scientific article published on 01 February 1993

[Morphologic studies of the anterior eye segment of the rat following long-term treatment with timolol]

scientific article published on 01 January 1988

List of works by Ernst R Tamm

Abnormal vessel formation in the choroid of mice lacking tissue inhibitor of metalloprotease-3.

Age changes in rhesus monkey ciliary muscle: light and electron microscopy

Age-related changes of the ciliary muscle in comparison with changes induced by treatment with prostaglandin F2 alpha. An ultrastructural study in rhesus and cynomolgus monkeys.

Age-related loss of ciliary muscle mobility in the rhesus monkey. Role of the choroid.

Age-related loss of morphologic responses to pilocarpine in rhesus monkey ciliary muscle

AlphaB-crystallin in lens development and muscle integrity: a gene knockout approach ⬇️

Ambiguous role of glucocorticoids on survival of retinal neurons.

Bone morphogenetic protein-7 is an antagonist of transforming growth factor-beta2 in human trabecular meshwork cells.

Carbonic anhydrase activity is increased in retinal pigmented epithelium and choriocapillaris of RCS rats

Cell cultures of human ciliary muscle: growth, ultrastructural and immunocytochemical characteristics

Characterization of muscarinic receptor involvement in human ciliary muscle cell function

Characterization of the mouse Myoc/Tigr gene.

Chromatin-remodeling factor Brg1 is required for Schwann cell differentiation and myelination

Connective tissue growth factor causes glaucoma by modifying the actin cytoskeleton of the trabecular meshwork.

Connective tissue growth factor induces extracellular matrix deposition in human trabecular meshwork cells.

Connective tissue growth factor modulates podocyte actin cytoskeleton and extracellular matrix synthesis and is induced in podocytes upon injury

Constitutive overexpression of Norrin activates Wnt/β-catenin and endothelin-2 signaling to protect photoreceptors from light damage

Contractile cells in the human scleral spur ⬇️

Correction: Identification of Pax6-Dependent Gene Regulatory Networks in the Mouse Lens.

Correction: Progressive Retinal Degeneration and Glial Activation in the CLN6nclf Mouse Model of Neuronal Ceroid Lipofuscinosis: A Beneficial Effect of DHA and Curcumin Supplementation.

Cre recombinase expression or topical tamoxifen treatment do not affect retinal structure and function, neuronal vulnerability or glial reactivity in the mouse eye.

Current aspects of aqueous humor dynamics and glaucoma

Deletion of ocular transforming growth factor β signaling mimics essential characteristics of diabetic retinopathy

Development of the human eye ⬇️

Different cell populations in bovine trabecular meshwork: An ultrastructural and immunocytochemical study ⬇️

Different collagen types define two types of idiopathic epiretinal membranes

Differential angiogenic properties of lithium chloride in vitro and in vivo.

Disruption of the retinitis pigmentosa 28 gene Fam161a in mice affects photoreceptor ciliary structure and leads to progressive retinal degeneration

Donor corneoscleral buttons: a new source of trabecular meshwork for research.

Ectopic norrin induces growth of ocular capillaries and restores normal retinal angiogenesis in Norrie disease mutant mice.

Effect of heparin II domain of fibronectin on aqueous outflow in cultured anterior segments of human eyes.

Effects of elevated intraocular pressure on outflow facility and TIGR/MYOC expression in perfused human anterior segments.

Effects of transforming growth factor-beta1 and basic fibroblast growth factor on proliferation of cell cultures derived from human vestibular nerve schwannoma.

Electrogenic sodium-bicarbonate cotransport in human ciliary muscle cells.

Epithelial-mesenchymal transition of the retinal pigment epithelium causes choriocapillaris atrophy

Establishment of myelinating Schwann cells and barrier integrity between central and peripheral nervous systems depend on Sox10.

Focus on Molecules: Myocilin/TIGR.

Focus on molecules: Norrin

Formation of fenestrae in murine liver sinusoids depends on plasmalemma vesicle-associated protein and is required for lipoprotein passage.

Gap junctions are found between iris sphincter smooth muscle cells but not in the ciliary muscle of human and monkey eyes

Gene expression profiling of TGFbeta2- and/or BMP7-treated trabecular meshwork cells: Identification of Smad7 as a critical inhibitor of TGF-beta2 signaling.

Gene targeting reveals a widespread role for the high-mobility-group transcription factor Sox11 in tissue remodeling

Genetic dissection of Pax6 dosage requirements in the developing mouse eye

Heterozygote Wdr36-deficient mice do not develop glaucoma

Heterozygous modulation of TGF-β signaling does not influence Müller glia cell reactivity or proliferation following NMDA-induced damage

Identification of adult stem cells in Schwalbe's line region of the primate eye.

Identification of pax6-dependent gene regulatory networks in the mouse lens

Immunohistochemical characterization of the 'intimal proliferation' phenomenon in Sneddon's syndrome and essential thrombocythaemia.

Immunohistochemical localization of neuropeptides in the human ciliary ganglion

Inactivation of the murine X-linked juvenile retinoschisis gene, Rs1h, suggests a role of retinoschisin in retinal cell layer organization and synaptic structure

Increase in types IV and VI collagen in cherry haemangiomas

Increased expression of olfactomedin-1 and myocilin in podocytes during puromycin aminonucleoside nephrosis.

Innervation of myofibroblast-like scleral spur cells in human monkey eyes

Intraocular Pressure and the Mechanisms Involved in Resistance of the Aqueous Humor Flow in the Trabecular Meshwork Outflow Pathways.

Kidney podocytes as specific targets for cyclo(RGDfC)-modified nanoparticles.

Lack of WDR36 leads to preimplantation embryonic lethality in mice and delays the formation of small subunit ribosomal RNA in human cells in vitro.

Lack of endothelial diaphragms in fenestrae and caveolae of mutant Plvap-deficient mice

Laminin Promotes Differentiation, Adhesion and Proliferation of Cell Cultures Derived from Human Acoustic Nerve Schwannoma

Latanoprost induces matrix metalloproteinase-1 expression in human nonpigmented ciliary epithelial cells through a cyclooxygenase-2-dependent mechanism.

Localization of myocilin/trabecular meshwork--inducible glucocorticoid response protein in the human eye

MicroRNAs are essential for differentiation of the retinal pigmented epithelium and maturation of adjacent photoreceptors

Modulation of myocilin/TIGR expression in human trabecular meshwork.

Morphological study of the anterior segment of cynomolgus monkey eyes following treatment with prostaglandin F2 alpha

Multivalent nanoparticles bind the retinal and choroidal vasculature.

Mutated olfactomedin 1 in the interphotoreceptor matrix of the mouse retina causes functional deficits and vulnerability to light damage

Myocilin and glaucoma: facts and ideas.

Myocilin in the trabecular meshwork of eyes with primary open-angle glaucoma

Myocilin is expressed in the glomerulus of the kidney and induced in mesangioproliferative glomerulonephritis

Myocilin modulates programmed cell death during retinal development

Müller cells and microglia of the mouse eye react throughout the entire retina in response to the procedure of an intravitreal injection

N-methyl-D-aspartate (NMDA)-mediated excitotoxic damage: a mouse model of acute retinal ganglion cell damage

Nerve cells in the human ciliary muscle: ultrastructural and immunocytochemical characterization

Nerve endings with structural characteristics of mechanoreceptors in the human scleral spur

Neuroprotection in glaucoma

Nitrergic nerve cells in the primate ciliary muscle are only present in species with a fovea centralis

Norrin Protects Retinal Ganglion Cells from Excitotoxic Damage via the Induction of Leukemia Inhibitory Factor

Norrin mediates angiogenic properties via the induction of insulin-like growth factor-1.

Norrin mediates neuroprotective effects on retinal ganglion cells via activation of the Wnt/beta-catenin signaling pathway and the induction of neuroprotective growth factors in Muller cells.

Norrin promotes vascular regrowth after oxygen-induced retinal vessel loss and suppresses retinopathy in mice.