List of works - Keiryn L Bennett

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

scientific article (publication date: 10 January 2002)

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

scientific article

The CRAPome: a contaminant repository for affinity purification-mass spectrometry data

scientific article

Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets

scientific article published on 24 August 2007

RNase P without RNA: identification and functional reconstitution of the human mitochondrial tRNA processing enzyme

scientific article

Gene essentiality and synthetic lethality in haploid human cells

scientific journal article

IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA

scientific article

SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1

scientific article

An efficient tandem affinity purification procedure for interaction proteomics in mammalian cells

scientific article

A chemical and phosphoproteomic characterization of dasatinib action in lung cancer

scientific article

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS

scientific article

The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib

scholarly article

Viral immune modulators perturb the human molecular network by common and unique strategies

scientific article

Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

scientific article

The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response

scientific article

Charting the molecular network of the drug target Bcr-Abl

scientific article

CD14 is a coreceptor of Toll-like receptors 7 and 9.

scientific article

Human Proteinpedia enables sharing of human protein data

scientific article

A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain

scientific article

SAMHD1 is a nucleic-acid binding protein that is mislocalized due to aicardi-goutières syndrome-associated mutations

scientific article

Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity

scientific article

Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms

scientific article

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia

scientific article

Interactome of two diverse RNA granules links mRNA localization to translational repression in neurons.

scientific article published on 19 December 2013

A reversible gene trap collection empowers haploid genetics in human cells

scientific article published on 25 August 2013

Functional dissection of the TBK1 molecular network

scientific article

General statistical modeling of data from protein relative expression isobaric tags.

scientific article

Proteome-wide drug and metabolite interaction mapping by thermal-stability profiling.

scientific article

Proteomic analysis of human cataract aqueous humour: Comparison of one-dimensional gel LCMS with two-dimensional LCMS of unlabelled and iTRAQ®-labelled specimens.

scientific article published on 16 October 2010

Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML.

scientific article

Initial characterization of the human central proteome

scientific article

Viperin is an iron-sulfur protein that inhibits genome synthesis of tick-borne encephalitis virus via radical SAM domain activity

scientific journal article

JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia

scientific article

Subproteomics: identification of plasma membrane proteins from the yeast Saccharomyces cerevisiae

scientific article

Phosphopeptide detection and sequencing by matrix-assisted laser desorption/ionization quadrupole time-of-flight tandem mass spectrometry.

scientific article

Signaling initiated by overexpression of the fibroblast growth factor receptor-1 investigated by mass spectrometry

scientific article (publication date: 2003)

Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions

scientific article

The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity

scientific journal article

Coincidental loss of DOCK8 function in NLRP10-deficient and C3H/HeJ mice results in defective dendritic cell migration

scientific article

Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action

scientific article published on 9 February 2015

RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics.

scientific article

CD4(+) T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2.

scientific article

An integrated chemical biology approach identifies specific vulnerability of Ewing's sarcoma to combined inhibition of Aurora kinases A and B.

scientific article published on 18 July 2011

LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning.

scientific article

Introduction to computational proteomics

scientific article

Using iTRAQ combined with tandem affinity purification to enhance low-abundance proteins associated with somatically mutated EGFR core complexes in lung cancer.

scientific article

The RNA-binding protein HuR/ELAVL1 regulates IFN-β mRNA abundance and the type I IFN response

scientific article published on 12 March 2015

A Pilot Proteogenomic Study with Data Integration Identifies MCT1 and GLUT1 as Prognostic Markers in Lung Adenocarcinoma

scientific article published on November 5, 2015

Germline RBBP6 mutations in familial myeloproliferative neoplasms.

scientific article published on 16 November 2015

Peptide end sequencing by orthogonal MALDI tandem mass spectrometry

scientific article

List of works by Keiryn L Bennett

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

The CRAPome: a contaminant repository for affinity purification-mass spectrometry data

Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets

RNase P without RNA: identification and functional reconstitution of the human mitochondrial tRNA processing enzyme

Gene essentiality and synthetic lethality in haploid human cells

IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA

SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1

An efficient tandem affinity purification procedure for interaction proteomics in mammalian cells

A chemical and phosphoproteomic characterization of dasatinib action in lung cancer

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS

The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib

Viral immune modulators perturb the human molecular network by common and unique strategies

Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response

Charting the molecular network of the drug target Bcr-Abl

CD14 is a coreceptor of Toll-like receptors 7 and 9.

Human Proteinpedia enables sharing of human protein data

A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain

SAMHD1 is a nucleic-acid binding protein that is mislocalized due to aicardi-goutières syndrome-associated mutations

Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity

Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia

Interactome of two diverse RNA granules links mRNA localization to translational repression in neurons.

A reversible gene trap collection empowers haploid genetics in human cells

Functional dissection of the TBK1 molecular network

General statistical modeling of data from protein relative expression isobaric tags.

Proteome-wide drug and metabolite interaction mapping by thermal-stability profiling.

Proteomic analysis of human cataract aqueous humour: Comparison of one-dimensional gel LCMS with two-dimensional LCMS of unlabelled and iTRAQ®-labelled specimens.

Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML.

Initial characterization of the human central proteome

Viperin is an iron-sulfur protein that inhibits genome synthesis of tick-borne encephalitis virus via radical SAM domain activity

JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia

Subproteomics: identification of plasma membrane proteins from the yeast Saccharomyces cerevisiae

Phosphopeptide detection and sequencing by matrix-assisted laser desorption/ionization quadrupole time-of-flight tandem mass spectrometry.

Signaling initiated by overexpression of the fibroblast growth factor receptor-1 investigated by mass spectrometry

Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions

The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity

Coincidental loss of DOCK8 function in NLRP10-deficient and C3H/HeJ mice results in defective dendritic cell migration

Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action

RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics.

CD4(+) T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2.

An integrated chemical biology approach identifies specific vulnerability of Ewing's sarcoma to combined inhibition of Aurora kinases A and B.

LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning.

Introduction to computational proteomics

Using iTRAQ combined with tandem affinity purification to enhance low-abundance proteins associated with somatically mutated EGFR core complexes in lung cancer.

The RNA-binding protein HuR/ELAVL1 regulates IFN-β mRNA abundance and the type I IFN response

A Pilot Proteogenomic Study with Data Integration Identifies MCT1 and GLUT1 as Prognostic Markers in Lung Adenocarcinoma

Germline RBBP6 mutations in familial myeloproliferative neoplasms.

Peptide end sequencing by orthogonal MALDI tandem mass spectrometry