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List of works by Ilva D. Rupenthal

3-Dimensionally ordered macroporous PEDOT ion-exchange resins prepared by vapor phase polymerization for triggered drug delivery: Fabrication and characterization

Brinzolamide-loaded nanoemulsions: ex vivo transcorneal permeation, cell viability and ocular irritation tests

scientific article published on 15 January 2019

Characterization and evaluation of β-glucan formulations as injectable implants for protein and peptide delivery.

scientific article

Characterization of NLRP3 Inflammasome Activation in the Onset of Diabetic Retinopathy

scientific article published in 2022

Comparison of ion-activated in situ gelling systems for ocular drug delivery. Part 1: Physicochemical characterisation and in vitro release ⬇️

scientific article published on March 29, 2011

Comparison of ion-activated in situ gelling systems for ocular drug delivery. Part 2: Precorneal retention and in vivo pharmacodynamic study ⬇️

scientific article published on March 29, 2011

Connexin Hemichannel Block Using Orally Delivered Tonabersat Improves Outcomes in Animal Models of Retinal Disease

scientific article published on 01 January 2020

Connexin43 hemichannel block inhibits NLRP3 inflammasome activation in a human retinal explant model of diabetic retinopathy

scientific article published on 04 December 2020

Connexin43 hemichannel block protects against retinal pigment epithelial cell barrier breakdown

scientific article published on 27 April 2019

Connexin43 hemichannel block protects against the development of diabetic retinopathy signs in a mouse model of the disease

scientific article published on 08 December 2018

Connexin43 hemichannels: A potential drug target for the treatment of diabetic retinopathy

scientific article published on 25 January 2019

Connexin43 in retinal injury and disease

scientific article published on 30 September 2015

Corrigendum to "Overcoming ocular drug delivery barriers through the use of physical forces" [Advanced Drug Delivery Reviews 126 (2018) 96-112]

scientific article published on 01 January 2019

Cytotoxicity and vitreous stability of chemically modified connexin43 mimetic peptides for the treatment of optic neuropathy.

scientific article published on 20 May 2013

Cytotoxicity considerations and electrically tunable release of dexamethasone from polypyrrole for the treatment of back-of-the-eye conditions.

scientific article

Dendrimers for gene delivery--a potential approach for ocular therapy?

scientific article published on 19 July 2013

Depot formulations to sustain periocular drug delivery to the posterior eye segment

scientific article published on 28 March 2019

Development of a novel stability indicating RP-HPLC method for quantification of Connexin43 mimetic peptide and determination of its degradation kinetics in biological fluids

scientific article published on 23 June 2017

Development of gatifloxacin-loaded cationic polymeric nanoparticles for ocular drug delivery

scientific article published on 12 October 2015

Differential Action of Connexin Hemichannel and Pannexin Channel Therapeutics for Potential Treatment of Retinal Diseases

scientific article published in 2021

Drug delivery to the lens for the management of cataracts

scientific article published on 28 March 2018

Drug-device combination approaches for delivery to the eye.

scientific article

Effects of enzymatic degradation on dynamic mechanical properties of the vitreous and intravitreal nanoparticle mobility

scientific article published on 21 March 2018

Electro-responsive macroporous polypyrrole scaffolds for triggered dexamethasone delivery.

scientific article published on 30 June 2015

Erratum to "Ultrasound-mediated nanoparticle delivery across ex vivo bovine retina after intravitreal injection" [Eur. J. Pharm. Biopharm. 119 (2017) 125-136].

scientific article published on 5 December 2017

Evaluation of 2 ex vivo Bovine Cornea Storage Protocols for Drug Delivery Applications

scientific article published on 22 November 2018

Evaluation of Fluorescence Resonance Energy Transfer Approaches as a Tool to Quantify the Stability of Antisense Oligodeoxynucleotides

scientific article published in February 2012

Ex vivo and In vivo Evaluation of Chitosan Coated Nanostructured Lipid Carriers for Ocular Delivery of Acyclovir

scientific article

Ex vivo evaluation of the influence of pH on the ophthalmic safety, antibacterial efficacy and storage stability of povidone-iodine

scientific article published on 03 June 2020

Ex vivo evaluation of the stability, safety and antibacterial efficacy of an extemporaneous povidone-iodine preparation for ophthalmic applications

scientific article published on 28 March 2019

Ex vivo investigation of ocular tissue distribution following intravitreal administration of connexin43 mimetic peptide using the microdialysis technique and LC-MS/MS.

scientific article published in July 2016

Extracellular Vesicles as Biomarkers and Therapeutics for Inflammatory Eye Diseases

article published in 2022

Formulation Considerations for the Management of Dry Eye Disease

Formulation Development and Evaluation of the Therapeutic Efficacy of Brinzolamide Containing Nanoemulsions

scientific article published in January 2017

Hyaluronic Acid Coated Albumin Nanoparticles for Targeted Peptide Delivery to the Retina.

scientific article published on 20 December 2016

Hyaluronic acid coated albumin nanoparticles for targeted peptide delivery in the treatment of retinal ischaemia

scientific article published on 20 March 2018

Imaging Techniques and their Role in Dosage form Design and Drug Delivery Research

scholarly article by Susanne Franke et al published 1 August 2008 in Current Pharmaceutical Analysis

Immunohistochemical Characterization of Connexin43 Expression in a Mouse Model of Diabetic Retinopathy and in Human Donor Retinas

scientific article published on 29 November 2017

Implants for drug delivery to the posterior segment of the eye: a focus on stimuli-responsive and tunable release systems

scientific article

Improved corneal wound healing through modulation of gap junction communication using connexin43-specific antisense oligodeoxynucleotides.

scientific article

In vitro and ex vivo corneal penetration and absorption models.

scientific article

In vitro release characteristics and cellular uptake of poly(D,L-lactic-co-glycolic acid) nanoparticles for topical delivery of antisense oligodeoxynucleotides

scientific article published on 22 June 2011

Incorporation of ion exchange functionalized-montmorillonite into solid lipid nanoparticles with low irritation enhances drug bioavailability for glaucoma treatment

scientific article published on 01 December 2020

Injectable implants for the sustained release of protein and peptide drugs.

scientific article published on 11 February 2013

Intracellular oligonucleotide delivery using the cell penetrating peptide Xentry

scientific article published on 26 July 2018

Intravitreal injection of lipoamino acid-modified connexin43 mimetic peptide enhances neuroprotection after retinal ischemia.

scientific article published on 4 August 2015

Intravitreal pro-inflammatory cytokines in non-obese diabetic mice: Modelling signs of diabetic retinopathy

scientific article published in PLoS ONE

Ion-Activated In Situ Gelling Systems for Antisense Oligodeoxynucleotide Delivery to the Ocular Surface ⬇️

scientific article published on November 3, 2011

Light-responsive in situ forming injectable implants for effective drug delivery to the posterior segment of the eye.

scientific article published on 11 March 2016

Medicated ocular bandages and corneal health: potential excipients and active pharmaceutical ingredients

scientific article published on 6 September 2017

Micelle directed chemical polymerization of polypyrrole particles for the electrically triggered release of dexamethasone base and dexamethasone phosphate.

scientific article published on 23 March 2018

Modern approaches to the ocular delivery of cyclosporine A.

scientific article published on 11 April 2016

Nanocarrier mediated retinal drug delivery: overcoming ocular barriers to treat posterior eye diseases.

scientific article published on 20 April 2017

Nanoparticle cross-linked collagen shields for sustained delivery of pilocarpine hydrochloride

scientific article published on 29 January 2016

Nanoparticle-loaded biodegradable light-responsive in situ forming injectable implants for effective peptide delivery to the posterior segment of the eye.

scientific article published on April 2017

Neuroprotection in the treatment of glaucoma--A focus on connexin43 gap junction channel blockers.

scientific article

Ocular Distribution of Papaverine Using Non-aqueous Vehicles

Ocular Drug Delivery

Ocular delivery of antisense oligonucleotides using colloidal Carriers: improving the wound repair after corneal surgery ⬇️

2008 doctoral thesis by Ilva Dana Rupenthal at University of Auckland

Ocular delivery systems for topical application of anti-infective agents

scientific article published on September 2015

Ocular drug delivery-eye on innovation

scientific article published on 01 December 2016

Ocular drugs and drug delivery systems - Current trends and future perspectives

scientific article published on 19 July 2019

Orally Delivered Connexin43 Hemichannel Blocker, Tonabersat, Inhibits Vascular Breakdown and Inflammasome Activation in a Mouse Model of Diabetic Retinopathy

scientific article published in 2023

Overcoming ocular drug delivery barriers through the use of physical forces.

scientific article published on 12 September 2017

PLGA nanoparticles for intravitreal peptide delivery: statistical optimization, characterization and toxicity evaluation.

scientific article

Phase transition of a microemulsion upon addition of cyclodextrin - applications in drug delivery.

scientific article published on 22 August 2017

Polymeric micelles for ocular drug delivery: From structural frameworks to recent preclinical studies.

scientific article published on 10 January 2017

Preclinical development of MGO Manuka Honey microemulsion for blepharitis management

article

Preclinical studies evaluating the effect of semifluorinated alkanes on ocular surface and tear fluid dynamics

scientific article published on 02 March 2019

Preparation and Characterisation of a Cyclodextrin-Complexed Mānuka Honey Microemulsion for Eyelid Application

Randomised masked trial of the clinical safety and tolerability of MGO Manuka Honey eye cream for the management of blepharitis

scientific article published on 04 August 2017

Relationship between rheological properties and transverse relaxation time (T2) of artificial and porcine vitreous humour

scientific article published on 17 March 2020

Role of gap junctions in chronic pain

scientific article published on 04 October 2011

Semifluorinated alkane based systems for enhanced corneal penetration of poorly soluble drugs

scientific article published on 12 January 2018

Sustained Connexin43 Mimetic Peptide Release From Loaded Nanoparticles Reduces Retinal and Choroidal Photodamage

scientific article published on 01 July 2018

Sustained intravitreal delivery of connexin43 mimetic peptide by poly(D,L-lactide-co-glycolide) acid micro- and nanoparticles--Closing the gap in retinal ischaemia

scientific article published on 9 December 2014

Synergistic effect of chemical penetration enhancer and iontophoresis on transappendageal transport of oligodeoxynucleotides

scientific article published on 23 October 2012

Targeting connexin hemichannels to control the inflammasome: the correlation between connexin43 and NLRP3 expression in chronic eye disease

scientific article published on 11 October 2019

The inflammasome pathway is amplified and perpetuated in an autocrine manner through connexin43 hemichannel mediated ATP release

scientific article published on 17 November 2017

The influence of hyperglycaemia on the safety of ultrasound in retinal pigment epithelial cells

scientific article published on 13 October 2020

Tonabersat Inhibits Connexin43 Hemichannel Opening and Inflammasome Activation in an In Vitro Retinal Epithelial Cell Model of Diabetic Retinopathy

scientific article published on 30 December 2020

Tonabersat Prevents Inflammatory Damage in the Central Nervous System by Blocking Connexin43 Hemichannels.

scientific article published on 30 May 2017

Topical semifluorinated alkane-based azithromycin suspension for the management of ocular infections

scientific article published on 11 June 2019

Ultrasound-mediated nanoparticle delivery across ex vivo bovine retina after intravitreal injection.

scientific article

Ultrasound-responsive nanobubbles for enhanced intravitreal drug migration: An ex vivo evaluation

scientific article published on 17 January 2019

Validation of hyaluronic acid-agar-based hydrogels as vitreous humor mimetics for in vitro drug and particle migration evaluations

scientific article published on 22 January 2020

Xentry-Gap19 inhibits Connexin43 hemichannel opening especially during hypoxic injury

scientific article published on 21 April 2020

ZnO/PVP nanoparticles induce gelation in type I collagen

scientific article published in February 2016

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