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List of works by Mario Pazzagli

A chemiluminescent immunoassay for the direct measurement of urinary 5 alpha-androstane-3 alpha, 17 beta-diol-glucuronide in urine

scientific article published on 01 July 1989

A chemiluminescent method for the measurement of pregnanetriol-3 alpha-glucuronide in human diluted urine

scientific article (publication date: July 1989)

A high-resolution melting protocol for rapid and accurate differential diagnosis of thyroid nodules.

scientific article published on 22 June 2012

A novel protein from the serum of Python sebae, structurally homologous with type-γ phospholipase A(2) inhibitor, displays antitumour activity.

scientific article

A solid phase chemiluminescent immunoassay (LIA) for testosterone glicuronide in diluted urines

scientific article published on 01 May 1983

Adenosine triphosphate release by osmotic shock and hemoglobin A1C in diabetic subjects' erythrocytes

scientific article published on 01 April 1994

Age-related changes in serum total antioxidant capacity (TAC), dehydroepiandrosterone sulphate (DHEAS), and insulin-like growth factor-1 (IGF-1): evidence in healthy centenarian subjects.

scientific article published in January 2002

Allele specific Taqman-based real-time PCR assay to quantify circulating BRAFV600E mutated DNA in plasma of melanoma patients

scientific article published on 31 May 2010

An Italian program of external quality control for quantitative assays based on real-time PCR with Taq-Man probes.

scientific article published on January 2005

An assay procedure for plasma progesterone based on antibody-enhanced chemiluminescence

scientific article published on 01 August 1979

An immunoassay for plasma cortisol based on chemiluminescence.

scientific article published on October 1980

Analysis of SAS gene and CDK4 and MDM2 proteins in low-grade osteosarcoma.

scientific article published in January 1999

Association between single nucleotide polymorphisms in the XRCC1 and RAD51 genes and clinical radiosensitivity in head and neck cancer

article

BRAFV600E detection in melanoma is highly improved by COLD-PCR.

scientific article

Bevacizumab plus XELOX as first-line treatment of metastatic colorectal cancer: The OBELIX study

scientific article published on June 2015

Biological parameters for the choice of antiangiogenic therapy and efficacy monitoring.

scientific article

Chemiluminescence immunoassay for somatomedin C in serum.

scientific article published on November 1987

Circulating BRAFV600E in the diagnosis and follow-up of differentiated papillary thyroid carcinoma.

scientific article published on 20 June 2013

Circulating Benign Nevus Cells Detected by ISET Technique

scientific article published on 01 October 2010

Circulating cell-free DNA in cancer

scientific article

Circulating cell-free DNA in plasma of melanoma patients: qualitative and quantitative considerations.

scientific article

Circulating nucleic acids in cancer and pregnancy

scientific article published on 08 February 2010

Circulating tumor cells detection and counting in uveal melanomas by a filtration-based method

scientific article

Combining qualitative and quantitative imaging evaluation for the assessment of genomic DNA integrity: The SPIDIA experience

scientific article

Comparison of pre- and postsurgical concentrations of blood HER-2 mRNA and HER-2 extracellular domain reflects HER-2 status in early breast cancer.

scientific article published in January 2005

Comparison of telomerase activity in bladder carcinoma and exfoliated cells collected in urine and bladder washings, using a quantitative assay

scientific article published on 01 July 2000

Considerations for the development of a reference method for sequencing of haploid DNA – an opinion paper on behalf of the IFCC Committee on Molecular Diagnostics. International Federation of Clinical Chemistry and Laboratory Medicine

article

Current Landscape and New Paradigms of Proficiency Testing and External Quality Assessment for Molecular Genetics ⬇️

scientific article published on July 1, 2013

DNA ploidy, S phase fraction and telomerase activity in gastric cancer

scientific article published on 01 January 1997

Detection of c-erbB-2 amplification in transitional cell bladder carcinoma using competitive PCR technique

scientific article published on 01 December 1996

Development and description of GETT: a genetic testing evidence tracking tool.

scientific article published on 27 July 2010

Developments in quantitative PCR.

scientific article

Diabetes mellitus and subjects' ageing: a study on the ATP content and ATP-related enzyme activities in human erythrocytes

scientific article published on 01 April 1997

EC4 European Syllabus for Post-Graduate Training in Clinical Chemistry and Laboratory Medicine: version 3 – 2005

scientific article published on 01 January 2006

EC4 European syllabus for post-graduate training in clinical chemistry. Version 2--1999. European Communities Confederation of Clinical Chemistry, EC4 Register Commission

scientific article published on 01 November 1999

EQUAL-qual: A European Program for External Quality Assessment of Genomic DNA Extraction and PCR Amplification

scientific article published on 01 July 2007

EQUAL-quant: an international external quality assessment scheme for real-time PCR.

scientific article published in June 2006

Early detection of Biscogniauxia nummularia in symptomless European beech (Fagus sylvatica L.) by TaqMan quantitative real-time PCR.

scientific article

Evaluation of different progesterone-isoluminol conjugates for chemiluminescence immunoassay

scientific article published on 01 September 1981

Evaluation of methotrexate sensitivity in human leukemia cell lines by an adenosine triphosphate bioluminescence assay

scientific article published on 01 September 1997

External quality assessment schemes for real-time PCR: a statistical procedure to corrective actions.

scientific article published in January 2008

External quality assurance program for PCR amplification of genomic DNA: an Italian experience

scientific article published on 01 May 2003

Gene amplification for c-erbB-2, c-myc, epidermal growth factor receptor, int-2, and N-myc measured by quantitative PCR with a multiple competitor template.

scientific article published on June 1995

Genetic and epigenetic factors in regulation of microRNA in colorectal cancers

scientific article published on 16 September 2012

Genetic variants in miR-146a, miR-149, miR-196a2, miR-499 and their influence on relative expression in lung cancers

scientific article

Glycated hemoglobin (HbA1c) measurement in frozen whole blood depends on baseline values of fresh samples.

scientific article published on 20 October 2012

Heterogeneity of PIK3CA mutational status at the single cell level in circulating tumor cells from metastatic breast cancer patients

scientific article published on 9 December 2014

High-Resolution Melting Analysis: a new molecular approach for the early detection of Diplodia pinea in Austrian pine

article

High-resolution melting analysis for rapid detection of KRAS, BRAF, and PIK3CA gene mutations in colorectal cancer

scientific article published on 01 August 2008

Homogeneous luminescence immunoassay for total estrogens in urine

scientific article published on 01 May 1984

Image analysis in quantitative PCR. An application for the measurement of c-erbB-2 oncogene amplification in DNA from human tumours

scientific article published on 01 May 1994

Immunoassays monitored by chemiluminescence

scientific article published on 01 January 1988

Immunometric assay for lutropin (hLH) based on the use of universal reagents for enzymatic labelling and magnetic separation and monitored by enhanced chemiluminescence

scientific article published on 01 November 1988

Implementation of a companion diagnostic in the clinical laboratory: the BRAF example in melanoma.

scientific article published on 23 October 2014

Implementation of a proficiency testing for the assessment of the preanalytical phase of blood samples used for RNA based analysis

scientific article published on 21 January 2012

Improvement of technical and analytical performance in DNA sequencing by external quality assessment-based molecular training

scientific article published on 21 September 2006

Influence of 17q gain and promoter polymorphisms on mRNA expression of somatostatin receptor type 2 in neuroblastoma

scientific article published on 13 July 2007

Influence of pre-analytical procedures on genomic DNA integrity in blood samples: the SPIDIA experience.

scientific article published on 6 December 2014

Influence of storage conditions and extraction methods on the quantity and quality of circulating cell-free DNA (ccfDNA): the SPIDIA-DNAplas External Quality Assessment experience

scientific article published on 01 November 2015

Is laboratory medicine ready for the era of personalized medicine? A survey addressed to laboratory directors of hospitals/academic schools of medicine in Europe

scientific article published on 01 June 2015

Is laboratory medicine ready for the era of personalized medicine? A survey addressed to laboratory directors of hospitals/academic schools of medicine in Europe.

scientific article

Isolation by size of epithelial tumor cells : a new method for the immunomorphological and molecular characterization of circulatingtumor cells

scientific article

Isolation by size of epithelial tumor cells in peripheral blood of patients with breast cancer: correlation with real-time reverse transcriptase-polymerase chain reaction results and feasibility of molecular analysis by laser microdissection

scientific article published in June 2006

Laser-assisted microdissection for real-time PCR sample preparation.

scientific article published on 9 February 2006

Longevity index (LI%) and centenarity index (CI%): new indicators to evaluate the characteristics of aging process in the Italian population

scientific article published on 14 August 2006

Luciferase gene as reporter: comparison with the CAT gene and use in transfection and microinjection of mammalian cells.

scientific article

Luminescent immunoassay (LIA) for progesterone in a heterogeneous system

scientific article published on 01 September 1981

Luminescent immunoassay (LIA) methods for steroid hormones

scientific article published on 01 October 1984

Luminescent immunoassay (LIA) of cortisol--1. Synthesis and evaluation of two chemiluminescent labels of cortisol

scientific article published on 01 October 1981

Luminescent immunoassay (LIA) of cortisol--2. Development and validation of the immunoassay monitored by chemiluminescence

scientific article published on 01 November 1981

Luminescent immunoassay using isoluminol derivatives

scientific article published on 01 July 1989

Measurement of 5 alpha-androstane-3 alpha, 17 beta-diol in human spermatic venous plasma by mass-fragmentography

scientific article published on 01 June 1980

Measurement of estrone-3-glucuronide and pregnanediol-3 alpha-glucuronide in early morning urine samples to monitor ovarian function

scientific article published on 01 July 1989

Measurement of glucuronometabolites of 17 beta-estradiol and progesterone in diluted overnight urine. An approach to the study of luteal insufficiency

scientific article published on 01 January 1987

Measurement of steroids in human plasma and tissues by isotope dilution mass spectrometry

scientific article published on 01 January 1990

Measurement of testosterone and its 5-alfa-reduced metabolites in human prostatic tissue using isotope dilution mass spectrometry

scientific article published on 01 November 1986

Measuring c-erbB-2 oncogene amplification in fresh and paraffin-embedded tumors by competitive polymerase chain reaction

scientific article published on 01 April 1994

Melting temperature analysis as quantitative method for detection of point mutations

scientific article published on 01 June 2001

Methodologic European external quality assurance for DNA sequencing: the EQUALseq program.

scientific article

Multidrug resistance in ovarian cancer: comparing an immunocytochemical study and ATP-tumor chemosensitivity assay.

scientific article published in October 2002

Multiparametric analysis of cell-free DNA in melanoma patients

scientific article

Nucleic acid reference materials (NARMs): definitions and issues ⬇️

scientific article published on October 25, 2010

On-line computer analysis of chemiluminescent reactions, with application to a luminescent immunoassay for free cortisol in urine

scientific article published on 01 October 1984

On-line computer analysis of the kinetics of chemiluminescent reactions: application to luminescent immunoassays

scientific article published on 01 January 1986

Ovarian function in premenopausal women affected by breast cancer: the measurement of glucuronoconjugate metabolites of 17 beta-estradiol and progesterone throughout one entire menstrual cycle

scientific article published on 01 August 1990

Preparation and evaluation of steroid chemiluminescent tracers

scientific article published on 01 July 1983

Prevalence and number of circulating tumour cells and microemboli at diagnosis of advanced NSCLC.

scientific article published on 26 July 2015

Prospective evaluation of RASSF1A cell-free DNA as a biomarker of pre-eclampsia

scientific article

Prostate-specific antigen mRNA and protein levels in laser microdissected cells of human prostate measured by real-time reverse transcriptase-quantitative polymerase chain reaction and immuno-quantitative polymerase chain reaction

scientific article

Quantitation of somatostatin receptor type 2 gene expression in neuroblastoma cell lines and primary tumors using competitive reverse transcription-polymerase chain reaction

scientific article published on 01 October 1996

Quantitative RT-PCR assay for VEGF mRNA in human tumors of the kidney

scientific article published on 01 October 1999

Quantitative analysis of carbonic anhydrase IX mRNA in human non-small cell lung cancer

scientific article published on 28 February 2006

Quantitative determination of sst2 gene expression in neuroblastoma tumor predicts patient outcome

scientific article published on 01 October 2000

Quantitative polymerase chain reaction-based homogeneous assay with fluorogenic probes to measure c-erbB-2 oncogene amplification

scientific article published on 01 May 1997

Quantitative real-time reverse transcription polymerase chain reaction: normalization to rRNA or single housekeeping genes is inappropriate for human tissue biopsies.

scientific article published in October 2002

Rapid, quantitative nonisotopic assay for telomerase activity in human tumors

scientific article published on 01 October 1998

Real-Time quantitative reverse transcriptase-polymerase chain reaction (RT-PCR) for the measurement of prostate-specific antigen mRNA in the peripheral blood of patients with prostate carcinoma using the taqman detection system.

scientific article

Real-time PCR detection of Biscogniauxia mediterranea in symptomless oak tissue.

scientific article

Real-time RT-PCR for the measurement of prostate-specific antigen mRNA expression in benign hyperplasia and adenocarcinoma of prostate

scientific article published on 01 March 2003

Real-time quantitative PCR for the measurement of MYCN amplification in human neuroblastoma with the TaqMan detection system

scientific article published on 01 November 1999

Red or white wine assumption and serum antioxidant capacity.

scientific article published on 15 January 2010

Reduced serum antioxidant capacity in healthy centenarians

scientific article published on 01 May 1997

SPIDIA-DNA: an External Quality Assessment for the pre-analytical phase of blood samples used for DNA-based analyses.

scientific article published on 25 May 2013

SPIDIA-RNA: first external quality assessment for the pre-analytical phase of blood samples used for RNA based analyses.

scientific article published on 27 October 2012

SPIDIA-RNA: second external quality assessment for the pre-analytical phase of blood samples used for RNA based analyses

scientific article

Serum antioxidant capacity in healthy and diabetic subjects as determined by enhanced chemiluminescence

scientific article published on 01 September 1998

Serum dehydroepiandrosterone sulfate (DHEA-S) and total antioxidant capacity (TAC) in healthy centenarian subjects

scientific article published on 01 January 1999

Serum total antioxidant capacity, DHEAS and IGF-I in healthy centenarian subjects.

scientific article

Somatostatin receptor type 2 gene expression in neuroblastoma, measured by competitive RT-PCR, is related to patient survival and to somatostatin receptor imaging by indium -111-pentetreotide

scientific article published on 01 January 2001

Somatostatin receptors in non-endocrine tumours

scientific article published in September 2001

Spermatic and peripheral oestradiol levels in patients affected by azoospermia due to seminiferous tubular damage

scientific article published on 01 April 1981

Statistical diagnostics emerging from external quality control of real-time PCR

scientific article published on 01 April 2004

TCA-100 tumour chemosensitivity assay: differences in sensitivity between cultured tumour cell lines and clinical studies.

scientific article published on November 1994

Tankyrase, a positive regulator of telomere elongation, is over expressed in human breast cancer

scientific article published in December 2004

Telomerase activity is significantly enhanced in malignant adrenocortical tumors in comparison to benign adrenocortical adenomas

scientific article published on 01 January 2000

The EC4 European Register of Specialists in Clinical Chemistry and Laboratory Medicine

scientific article published on 27 March 2008

The European Register for Specialists in Clinical Chemistry and Laboratory Medicine: Code of Conduct.

scientific article published in May 2004

The European Register for Specialists in Clinical Chemistry and Laboratory Medicine: guide to the Register Version 2-2003 and procedure for re-registration.

scientific article published in February 2003

The c-erbB-2 oncogene amplification by competitive PCR in aneuploid cell clones flow sorted from breast cancer samples.

scientific article published on June 1999

The practice of clinical chemistry in the European Union

scientific article published on 01 February 2002

Two novel H-RAS mutations identified in a child with an atypical spitzoid tumor.

scientific article

Use of bacterial and firefly luciferases as reporter genes in DEAE-dextran-mediated transfection of mammalian cells

scientific article published on August 1, 1992

[An angiogenesis study of Dukes' B colonic tumors]

scientific article published on 01 September 1999

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