List of works - Irene Franco

Deficiency of cannabinoid receptor of type 2 worsens renal functional and structural abnormalities in streptozotocin-induced diabetic mice

scientific article published on 14 May 2014

Distinct effects of leukocyte and cardiac phosphoinositide 3-kinase γ activity in pressure overload-induced cardiac failure

scientific article published on 17 January 2011

Healthy skeletal muscle aging: The role of satellite cells, somatic mutations and exercise

scientific article published on 12 April 2019

Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function

scientific article published in October 2017

Morgana acts as an oncosuppressor in chronic myeloid leukemia.

scientific article published on 12 February 2015

Myocyte signalling in leucocyte recruitment to the heart

scientific article published on 05 February 2014

PI3-kinase γ promotes Rap1a-mediated activation of myeloid cell integrin α4β1, leading to tumor inflammation and growth

scientific article

PI3K class II α controls spatially restricted endosomal PtdIns3P and Rab11 activation to promote primary cilium function

scientific article

PI3K in cancer-stroma interactions: bad in seed and ugly in soil.

scientific article published on 29 July 2013

PI3K-C2α: One enzyme for two products coupling vesicle trafficking and signal transduction.

scientific article published on 12 May 2015

Phosphoinositide 3-Kinase Gamma Inhibition Protects from Anthracycline Cardiotoxicity and Reduces Tumor Growth.

scientific article published on 18 January 2018

Phosphoinositide 3-Kinase γ Restrains Neurotoxic Effects of Microglia After Focal Brain Ischemia.

scientific article

Phosphoinositide 3-Kinase-C2α Regulates Polycystin-2 Ciliary Entry and Protects against Kidney Cyst Formation

scientific article published on 13 August 2015

Rac signal adaptation controls neutrophil mobilization from the bone marrow.

scientific article

Rare progerin-expressing preadipocytes and adipocytes contribute to tissue depletion over time

scientific article published on 30 June 2017

Receptor tyrosine kinases and TLR/IL1Rs unexpectedly activate myeloid cell PI3kγ, a single convergent point promoting tumor inflammation and progression.

scientific article

Reverting to old theories of ageing with new evidence for the role of somatic mutations

scientific article published in 2022

Somatic mutagenesis in satellite cells associates with human skeletal muscle aging

scientific article published on 23 February 2018

The Hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation

scientific article

The PI3K/Akt/mTOR pathway in polycystic kidney disease: A complex interaction with polycystins and primary cilium

scientific article published on 09 November 2019

The absence of functional PI3Kgamma prevents leukocyte recruitment and ameliorates DSS-induced colitis in mice.

scientific article published on 27 March 2010

Whole genome DNA sequencing provides an atlas of somatic mutagenesis in healthy human cells and identifies a tumor-prone cell type

scientific article published on 18 December 2019

List of works by Irene Franco

Deficiency of cannabinoid receptor of type 2 worsens renal functional and structural abnormalities in streptozotocin-induced diabetic mice

Distinct effects of leukocyte and cardiac phosphoinositide 3-kinase γ activity in pressure overload-induced cardiac failure

Healthy skeletal muscle aging: The role of satellite cells, somatic mutations and exercise

Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function

Morgana acts as an oncosuppressor in chronic myeloid leukemia.

Myocyte signalling in leucocyte recruitment to the heart

PI3-kinase γ promotes Rap1a-mediated activation of myeloid cell integrin α4β1, leading to tumor inflammation and growth

PI3K class II α controls spatially restricted endosomal PtdIns3P and Rab11 activation to promote primary cilium function

PI3K in cancer-stroma interactions: bad in seed and ugly in soil.

PI3K-C2α: One enzyme for two products coupling vesicle trafficking and signal transduction.

Phosphoinositide 3-Kinase Gamma Inhibition Protects from Anthracycline Cardiotoxicity and Reduces Tumor Growth.

Phosphoinositide 3-Kinase γ Restrains Neurotoxic Effects of Microglia After Focal Brain Ischemia.

Phosphoinositide 3-Kinase-C2α Regulates Polycystin-2 Ciliary Entry and Protects against Kidney Cyst Formation

Rac signal adaptation controls neutrophil mobilization from the bone marrow.

Rare progerin-expressing preadipocytes and adipocytes contribute to tissue depletion over time

Receptor tyrosine kinases and TLR/IL1Rs unexpectedly activate myeloid cell PI3kγ, a single convergent point promoting tumor inflammation and progression.

Reverting to old theories of ageing with new evidence for the role of somatic mutations

Somatic mutagenesis in satellite cells associates with human skeletal muscle aging

The Hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation

The PI3K/Akt/mTOR pathway in polycystic kidney disease: A complex interaction with polycystins and primary cilium

The absence of functional PI3Kgamma prevents leukocyte recruitment and ameliorates DSS-induced colitis in mice.

Whole genome DNA sequencing provides an atlas of somatic mutagenesis in healthy human cells and identifies a tumor-prone cell type