List of works - Nicolas Barnich

Abnormal CEACAM6 expression in Crohn disease patients favors gut colonization and inflammation by adherent-invasive E. coli.

scientific article published on July 2010

Abnormally expressed ER stress response chaperone Gp96 in CD favours adherent-invasive Escherichia coli invasion

scientific article

Activation of the EIF2AK4-EIF2A/eIF2α-ATF4 pathway triggers autophagy response to Crohn disease-associated adherent-invasive Escherichia coli infection

scientific article published on 17 March 2016

Adaptation of adherent-invasive E. coli to gut environment: Impact on flagellum expression and bacterial colonization ability.

scientific article

Adherent-Invasive E. coli enhances colonic hypersensitivity and P2X receptors expression during post-infectious period.

scientific article published on 14 August 2017

Adherent-Invasive E. coli: Update on the Lifestyle of a Troublemaker in Crohn's Disease ⬇️

scientific article published on 25 May 2020

Adherent-invasive Escherichia coli and Crohnʼs disease

scientific article

Adherent-invasive Escherichia coli induce claudin-2 expression and barrier defect in CEABAC10 mice and Crohn's disease patients.

scientific article

Adherent-invasive Escherichia coli phenotype displayed by intestinal pathogenic E. coli strains from cats, dogs, and swine.

scientific article

Adherent-invasive in inflammatory bowel disease

scientific article published on 15 November 2017

An adherent-invasive <i>Escherichia coli</i>-colonized mouse model to evaluate microbiota-targeting strategies in Crohn's disease

scientific article published in 2022

Analysis of the σE regulon in Crohn's disease-associated Escherichia coli revealed involvement of the waaWVL operon in biofilm formation

scientific article

Association of colorectal cancer with pathogenic Escherichia coli: Focus on mechanisms using optical imaging

scientific article

Bacteriophages Targeting Adherent Invasive Escherichia coli Strains as a Promising New Treatment for Crohn's Disease

scientific article published on 27 January 2017

Brilliant glyconanocapsules for trapping of bacteria

scientific article published on 01 August 2015

CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease

scientific article published on 24 May 2007

Centaurin beta1 down-regulates nucleotide-binding oligomerization domains 1- and 2-dependent NF-kappaB activation

scientific article

Chitin-binding domains of Escherichia coli ChiA mediate interactions with intestinal epithelial cells in mice with colitis

scientific article published on 16 May 2013

Colibactin-Producing Escherichia coli Induce the Formation of Invasive Carcinomas in a Chronic Inflammation-Associated Mouse Model

scientific article published in 2021

Comparative genomics of Crohn's disease-associated adherent-invasive Escherichia coli

scientific article published on 20 April 2016

Correction for Dreux et al., Ribonucleotide Reductase Repressor NrdR as a Novel Regulator for Motility and Chemotaxis during Adherent-Invasive Escherichia coli Infection.

scientific article published in October 2015

Crohn disease-associated Escherichia coli promote gastrointestinal inflammatory disorders by activation of HIF-dependent responses.

scientific article

Crohn's Disease-Associated Adherent-Invasive Escherichia coli Manipulate Host Autophagy by Impairing SUMOylation

scientific article published on 09 January 2019

Crohn's disease adherent-invasive Escherichia coli colonize and induce strong gut inflammation in transgenic mice expressing human CEACAM.

scientific article published on 08 September 2009

Crohn's disease-associated Escherichia coli LF82 aggravates colitis in injured mouse colon via signaling by flagellin.

scientific article

Development of Heptylmannoside-Based Glycoconjugate Antiadhesive Compounds against Adherent-Invasive Escherichia coli Bacteria Associated with Crohn's Disease.

scientific article

Diet-induced hypoxia responsive element demethylation increases CEACAM6 expression, favouring Crohn's disease-associated Escherichia coli colonisation.

scientific article

Differential miRNA-Gene Expression in M Cells in Response to Crohn's Disease-Associated AIEC

scientific article published on 07 August 2020

Differentiation of Crohn's Disease-Associated Isolates from Other Pathogenic Escherichia coli by Fimbrial Adhesion under Shear Force

scientific article published on April 2016

Emerging Role of Exosomes in Diagnosis and Treatment of Infectious and Inflammatory Bowel Diseases

scientific article published on 30 April 2020

Exosomes: From Functions in Host-Pathogen Interactions and Immunity to Diagnostic and Therapeutic Opportunities

scientific article published on 7 September 2016

Faecal chitinase 3-like 1 is a reliable marker as accurate as faecal calprotectin in detecting endoscopic activity in adult patients with inflammatory bowel diseases.

scientific article published on 8 March 2016

Fecal Matrix Metalloprotease-9 and Lipocalin-2 as Biomarkers in Detecting Endoscopic Activity in Patients With Inflammatory Bowel Diseases

scientific article published on 01 August 2018

GRIM-19 interacts with nucleotide oligomerization domain 2 and serves as downstream effector of anti-bacterial function in intestinal epithelial cells

scientific article

GipA Factor Supports Colonization of Peyer's Patches by Crohn's Disease-associated Escherichia Coli.

scientific article published on 28 October 2015

Glycopolymers as Antiadhesives of E. coli Strains Inducing Inflammatory Bowel Diseases.

scientific article

Gut Microbiota as Potential Biomarker and/or Therapeutic Target to Improve the Management of Cancer: Focus on Colibactin-Producing Escherichia coli in Colorectal Cancer

scientific article published in 2021

Gut microbiota imbalance and colorectal cancer

scientific article

High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn’s disease

scientific article

HtrA stress protein is involved in intramacrophagic replication of adherent and invasive Escherichia coli strain LF82 isolated from a patient with Crohn's disease

scientific article

Identification of virulence markers and phylogenetic groups association, and Antimicrobial Susceptibility of uropathogenic Escherichia coli isolates

scientific article published in 2022

Immunopathogenesis of inflammatory bowel disease

scientific article

In Memoriam, Arlette Darfeuille-Michaud, PhD.

scientific article published on 21 October 2014

In Memoriam, Arlette Darfeuille-Michaud, PhD.

scientific article published in November 2014

Influenza A virus infection of intestinal epithelial cells enhances the adhesion ability of Crohn's disease associated Escherichia coli strains

scientific article published on 23 February 2015

Inhibition profiles of mono- and polyvalent FimH antagonists against 10 different Escherichia coli strains.

scientific article published on 6 October 2015

Interactions between microsatellite instability and human gut colonization by Escherichia coli in colorectal cancer.

scientific article published on 16 January 2017

Intestinal Microbiota: A Novel Target to Improve Anti-Tumor Treatment?

scientific article published on 17 September 2019

Involvement of lipoprotein NlpI in the virulence of adherent invasive Escherichia coli strain LF82 isolated from a patient with Crohn's disease

scientific article published on May 2004

Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors

scientific article published on 10 December 2006

Macrophages Versus Escherichia coli: A Decisive Fight in Crohn's Disease

scientific article published on November 2016

Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognition

scientific article

Microbiota, Inflammation and Colorectal Cancer

scientific article

Monocyte-derived macrophages from Crohn's disease patients are impaired in the ability to control intracellular adherent-invasive Escherichia coli and exhibit disordered cytokine secretion profile.

scientific article published on 24 March 2015

Oral exposure to environmental pollutant benzo[a]pyrene impacts the intestinal epithelium and induces gut microbial shifts in murine model.

scientific article published on 09 August 2016

Physiochemical Tuning of Potent Escherichia coli Anti-Adhesives by Microencapsulation and Methylene Homologation

scientific article published on 3 March 2017

Point mutations in FimH adhesin of Crohn's disease-associated adherent-invasive Escherichia coli enhance intestinal inflammatory response

scientific article

Potential role of chitinases and chitin-binding proteins in host-microbial interactions during the development of intestinal inflammation

scientific article

Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease

scientific article published on 01 December 1998

Preventive Effect of Spontaneous Physical Activity on the Gut-Adipose Tissue in a Mouse Model That Mimics Crohn's Disease Susceptibility

scientific article published on 09 January 2019

Regulatory and functional co-operation of flagella and type 1 pili in adhesive and invasive abilities of AIEC strain LF82 isolated from a patient with Crohn's disease.

scientific article

Ribonucleotide reductase NrdR as a novel regulator for motility and chemotaxis during adherent-invasive Escherichia coli infection

scientific article

Role of bacteria in the etiopathogenesis of inflammatory bowel disease

scientific article published on November 2007

Saccharomyces cerevisiae CNCM I-3856 prevents colitis induced by AIEC bacteria in the transgenic mouse model mimicking Crohn's disease.

scientific article published on February 2015

Second generation of thiazolylmannosides, FimH antagonists for E. coli-induced Crohn's disease.

scientific article

The Antiadhesive Strategy in Crohn's Disease: Orally Active Mannosides to Decolonize Pathogenic Escherichia coli from the Gut

scientific article

The Vat-AIEC protease promotes crossing of the intestinal mucus layer by Crohn's disease-associated Escherichia coli.

scientific article published on 24 October 2015

The potential of FimH as a novel therapeutic target for the treatment of Crohn's disease.

scientific article

Toll-interacting protein modulates colitis susceptibility in mice.

scientific article

Transient inability to manage proteobacteria promotes chronic gut inflammation in TLR5-deficient mice

scientific article

Type 1 pili-mediated adherence of Escherichia coli strain LF82 isolated from Crohn's disease is involved in bacterial invasion of intestinal epithelial cells.

scientific article published on March 2001

Understanding host-adherent-invasive Escherichia coli interaction in Crohn's disease: opening up new therapeutic strategies

scientific article

Western diet induces a shift in microbiota composition enhancing susceptibility to Adherent-Invasive E. coli infection and intestinal inflammation

scientific article published on 8 January 2016

Western diet induces dysbiosis with increased E coli in CEABAC10 mice, alters host barrier function favouring AIEC colonisation

scientific article

Yersiniabactin Siderophore of Crohn’s Disease-Associated Adherent-Invasive Escherichia coli Is Involved in Autophagy Activation in Host Cells

scientific article published in 2021

[How some commensal bacteria would exacerbate colorectal carcinogenesis?].

scientific article published in February 2016

List of works by Nicolas Barnich

Abnormal CEACAM6 expression in Crohn disease patients favors gut colonization and inflammation by adherent-invasive E. coli.

Abnormally expressed ER stress response chaperone Gp96 in CD favours adherent-invasive Escherichia coli invasion

Activation of the EIF2AK4-EIF2A/eIF2α-ATF4 pathway triggers autophagy response to Crohn disease-associated adherent-invasive Escherichia coli infection

Adaptation of adherent-invasive E. coli to gut environment: Impact on flagellum expression and bacterial colonization ability.

Adherent-Invasive E. coli enhances colonic hypersensitivity and P2X receptors expression during post-infectious period.

Adherent-Invasive E. coli: Update on the Lifestyle of a Troublemaker in Crohn's Disease ⬇️

Adherent-invasive Escherichia coli and Crohnʼs disease

Adherent-invasive Escherichia coli induce claudin-2 expression and barrier defect in CEABAC10 mice and Crohn's disease patients.

Adherent-invasive Escherichia coli phenotype displayed by intestinal pathogenic E. coli strains from cats, dogs, and swine.

Adherent-invasive in inflammatory bowel disease

An adherent-invasive <i>Escherichia coli</i>-colonized mouse model to evaluate microbiota-targeting strategies in Crohn's disease

Analysis of the σE regulon in Crohn's disease-associated Escherichia coli revealed involvement of the waaWVL operon in biofilm formation

Association of colorectal cancer with pathogenic Escherichia coli: Focus on mechanisms using optical imaging

Bacteriophages Targeting Adherent Invasive Escherichia coli Strains as a Promising New Treatment for Crohn's Disease

Brilliant glyconanocapsules for trapping of bacteria

CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease

Centaurin beta1 down-regulates nucleotide-binding oligomerization domains 1- and 2-dependent NF-kappaB activation

Chitin-binding domains of Escherichia coli ChiA mediate interactions with intestinal epithelial cells in mice with colitis

Colibactin-Producing Escherichia coli Induce the Formation of Invasive Carcinomas in a Chronic Inflammation-Associated Mouse Model

Comparative genomics of Crohn's disease-associated adherent-invasive Escherichia coli

Correction for Dreux et al., Ribonucleotide Reductase Repressor NrdR as a Novel Regulator for Motility and Chemotaxis during Adherent-Invasive Escherichia coli Infection.

Crohn disease-associated Escherichia coli promote gastrointestinal inflammatory disorders by activation of HIF-dependent responses.

Crohn's Disease-Associated Adherent-Invasive Escherichia coli Manipulate Host Autophagy by Impairing SUMOylation

Crohn's disease adherent-invasive Escherichia coli colonize and induce strong gut inflammation in transgenic mice expressing human CEACAM.

Crohn's disease-associated Escherichia coli LF82 aggravates colitis in injured mouse colon via signaling by flagellin.

Development of Heptylmannoside-Based Glycoconjugate Antiadhesive Compounds against Adherent-Invasive Escherichia coli Bacteria Associated with Crohn's Disease.

Diet-induced hypoxia responsive element demethylation increases CEACAM6 expression, favouring Crohn's disease-associated Escherichia coli colonisation.

Differential miRNA-Gene Expression in M Cells in Response to Crohn's Disease-Associated AIEC

Differentiation of Crohn's Disease-Associated Isolates from Other Pathogenic Escherichia coli by Fimbrial Adhesion under Shear Force

Emerging Role of Exosomes in Diagnosis and Treatment of Infectious and Inflammatory Bowel Diseases

Exosomes: From Functions in Host-Pathogen Interactions and Immunity to Diagnostic and Therapeutic Opportunities

Faecal chitinase 3-like 1 is a reliable marker as accurate as faecal calprotectin in detecting endoscopic activity in adult patients with inflammatory bowel diseases.

Fecal Matrix Metalloprotease-9 and Lipocalin-2 as Biomarkers in Detecting Endoscopic Activity in Patients With Inflammatory Bowel Diseases

GRIM-19 interacts with nucleotide oligomerization domain 2 and serves as downstream effector of anti-bacterial function in intestinal epithelial cells

GipA Factor Supports Colonization of Peyer's Patches by Crohn's Disease-associated Escherichia Coli.

Glycopolymers as Antiadhesives of E. coli Strains Inducing Inflammatory Bowel Diseases.

Gut Microbiota as Potential Biomarker and/or Therapeutic Target to Improve the Management of Cancer: Focus on Colibactin-Producing Escherichia coli in Colorectal Cancer

Gut microbiota imbalance and colorectal cancer

High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn’s disease

HtrA stress protein is involved in intramacrophagic replication of adherent and invasive Escherichia coli strain LF82 isolated from a patient with Crohn's disease

Identification of virulence markers and phylogenetic groups association, and Antimicrobial Susceptibility of uropathogenic Escherichia coli isolates

Immunopathogenesis of inflammatory bowel disease

In Memoriam, Arlette Darfeuille-Michaud, PhD.

In Memoriam, Arlette Darfeuille-Michaud, PhD.

Influenza A virus infection of intestinal epithelial cells enhances the adhesion ability of Crohn's disease associated Escherichia coli strains

Inhibition profiles of mono- and polyvalent FimH antagonists against 10 different Escherichia coli strains.

Interactions between microsatellite instability and human gut colonization by Escherichia coli in colorectal cancer.

Intestinal Microbiota: A Novel Target to Improve Anti-Tumor Treatment?

Involvement of lipoprotein NlpI in the virulence of adherent invasive Escherichia coli strain LF82 isolated from a patient with Crohn's disease

Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors

Macrophages Versus Escherichia coli: A Decisive Fight in Crohn's Disease

Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognition

Microbiota, Inflammation and Colorectal Cancer

Monocyte-derived macrophages from Crohn's disease patients are impaired in the ability to control intracellular adherent-invasive Escherichia coli and exhibit disordered cytokine secretion profile.

Oral exposure to environmental pollutant benzo[a]pyrene impacts the intestinal epithelium and induces gut microbial shifts in murine model.

Physiochemical Tuning of Potent Escherichia coli Anti-Adhesives by Microencapsulation and Methylene Homologation

Point mutations in FimH adhesin of Crohn's disease-associated adherent-invasive Escherichia coli enhance intestinal inflammatory response

Potential role of chitinases and chitin-binding proteins in host-microbial interactions during the development of intestinal inflammation

Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease

Preventive Effect of Spontaneous Physical Activity on the Gut-Adipose Tissue in a Mouse Model That Mimics Crohn's Disease Susceptibility

Regulatory and functional co-operation of flagella and type 1 pili in adhesive and invasive abilities of AIEC strain LF82 isolated from a patient with Crohn's disease.

Ribonucleotide reductase NrdR as a novel regulator for motility and chemotaxis during adherent-invasive Escherichia coli infection

Role of bacteria in the etiopathogenesis of inflammatory bowel disease

Saccharomyces cerevisiae CNCM I-3856 prevents colitis induced by AIEC bacteria in the transgenic mouse model mimicking Crohn's disease.

Second generation of thiazolylmannosides, FimH antagonists for E. coli-induced Crohn's disease.

The Antiadhesive Strategy in Crohn's Disease: Orally Active Mannosides to Decolonize Pathogenic Escherichia coli from the Gut

The Vat-AIEC protease promotes crossing of the intestinal mucus layer by Crohn's disease-associated Escherichia coli.

The potential of FimH as a novel therapeutic target for the treatment of Crohn's disease.

Toll-interacting protein modulates colitis susceptibility in mice.

Transient inability to manage proteobacteria promotes chronic gut inflammation in TLR5-deficient mice

Type 1 pili-mediated adherence of Escherichia coli strain LF82 isolated from Crohn's disease is involved in bacterial invasion of intestinal epithelial cells.

Understanding host-adherent-invasive Escherichia coli interaction in Crohn's disease: opening up new therapeutic strategies

Western diet induces a shift in microbiota composition enhancing susceptibility to Adherent-Invasive E. coli infection and intestinal inflammation

Western diet induces dysbiosis with increased E coli in CEABAC10 mice, alters host barrier function favouring AIEC colonisation

Yersiniabactin Siderophore of Crohn’s Disease-Associated Adherent-Invasive Escherichia coli Is Involved in Autophagy Activation in Host Cells

[How some commensal bacteria would exacerbate colorectal carcinogenesis?].