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List of works by Nathalie Vergnolle

184 Regulation of the Enteric Neuromotor and Sensory Functions in the Mouse With N-Arachidonoyl-Serotonin (AA-5-HT), a Dual Fatty Acid Amide Hydrolase (FAAH) Inhibitor and TRPV1 Antagonist

scholarly article by Mohammad Bashashati et al published April 2016 in Gastroenterology

5-oxoETE triggers nociception in constipation-predominant irritable bowel syndrome through MAS-related G protein-coupled receptor D

scientific article published on 18 December 2018

811 ALTERATIONS IN INFLAMMATORY MEDIATORS IN A RAT MODEL OF CYCLOPHOSPHAMIDE-INDUCED ACUTE VISCERAL PAIN

A major role for proteolytic activity and proteinase-activated receptor-2 in the pathogenesis of infectious colitis

scientific article

A novel orally administered trimebutine compound (GIC-1001) is anti-nociceptive and features peripheral opioid agonistic activity and Hydrogen Sulphide-releasing capacity in mice.

scientific article published on 6 November 2015

A role for proteinase-activated receptor-1 in inflammatory bowel diseases.

scientific article published in July 2006

A role for proteinase-activated receptor–1 in inflammatory bowel diseases

A role for transient receptor potential vanilloid 4 in tonicity-induced neurogenic inflammation.

scientific article

A spontaneous mutation of the rat Themis gene leads to impaired function of regulatory T cells linked to inflammatory bowel disease

scientific article

A vasculo-protective circuit centered on lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 operative in murine microcirculation

scientific article published on 03 June 2013

Activated protein C based therapeutic strategies in chronic diseases

scientific article published on 20 March 2014

Activation of protease-activated receptor-1 (PAR-1) inhibits neurally evoked chloride secretion in the mouse colon

Activation of proteinase-activated receptor-1 inhibits neurally evoked chloride secretion in the mouse colon in vitro

scientific article published on 2 September 2004

Activation of the endogenous nociceptin system by selective nociceptin receptor agonist SCH 221510 produces antitransit and antinociceptive effect: a novel strategy for treatment of diarrhea-predominant IBS.

scientific article published on 15 July 2014

Active thrombin produced by the intestinal epithelium controls mucosal biofilms

scientific article published on 19 July 2019

Agonists of proteinase-activated receptor 1 induce plasma extravasation by a neurogenic mechanism

scientific article

Agonists of proteinase-activated receptor-2 affect transendothelial migration and apoptosis of human neutrophils

scientific article published in October 2007

Agonists of proteinase-activated receptor-2 enhance IFN-gamma-inducible effects on human monocytes: role in influenza A infection

scientific article

Agonists of proteinase-activated receptor-2 modulate human neutrophil cytokine secretion, expression of cell adhesion molecules, and migration within 3-D collagen lattices

scientific article

Agonists of proteinase-activated receptor-2 stimulate upregulation of intercellular cell adhesion molecule-1 in primary human keratinocytes via activation of NF-kappa B.

scientific article published in January 2005

Aluminum Ingestion Promotes Colorectal Hypersensitivity in Rodents

scientific article published on 20 September 2018

Analgesic properties of S100A9 C-terminal domain: a mechanism dependent on calcium channel inhibition

scientific article published on 8 June 2009

Annexin 1 Is Secreted in Situ During Ulcerative Colitis in Humans

scientific article published on 01 September 2004

Annexin 1 is Overexpressed and Specifically Secreted During Experimentally Induced Colitis in Rats

scientific article published in 1995

Annexin 1 is Overexpressed and Specifically Secreted During Experimentally Induced Colitis in Rats

scientific article published on 01 September 1995

Anti-inflammatory and anticancer effects of flavonol glycosides from Diplotaxis harra through GSK3β regulation in intestinal cells

scientific article published on 22 September 2016

Anti-inflammatory effects of nitric oxide-releasing hydrocortisone NCX 1022, in a murine model of contact dermatitis

scientific article published on 16 August 2004

Apelin targets gut contraction to control glucose metabolism via the brain

scientific article

Bladder telemetry: A new approach to evaluate micturition behavior under physiological and inflammatory conditions

scientific article published on 16 February 2016

Brain-gut interactions increase peripheral nociceptive signaling in mice with postinfectious irritable bowel syndrome

scientific article published on 19 August 2011

Characterization of the inflammatory response to proteinase-activated receptor-2 (PAR2)-activating peptides in the rat paw.

scientific article published on July 1999

Characterization of thrombin-induced leukocyte rolling and adherence: a potential proinflammatory role for proteinase-activated receptor-4

scientific journal article

Chronic stress mediators act synergistically on colonic nociceptive mouse dorsal root ganglia neurons to increase excitability.

scientific article

Citrobacter rodentium infection causes iNOS-independent intestinal epithelial dysfunction in mice

article

Clinical relevance of proteinase activated receptors (pars) in the gut

scientific article

Colitis induced by proteinase-activated receptor-2 agonists is mediated by a neurogenic mechanism

scientific article published in September 2003

Combined challenge of mice with Citrobacter rodentium and ionizing radiation promotes bacterial translocation.

scientific article published in June 2007

Contribution of bone marrow-derived cells to the pro-inflammatory effects of protease-activated receptor-2 in colitis

scientific article

Cultures d’organoïdes de vessie humaine : un nouveau modèle d’étude

article

Defects in 15-HETE Production and Control of Epithelial Permeability by Human Enteric Glial Cells From Patients With Crohn's Disease

scientific article

Derivatized 2-furoyl-LIGRLO-amide, a versatile and selective probe for proteinase-activated receptor 2: binding and visualization

scientific article

Development, plasticity and modulation of visceral afferents

scientific article

Differential role of N-type calcium channel splice isoforms in pain.

scientific article

Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2

scientific article published on 13 March 2019

Effect of tryptase inhibition on joint inflammation: a pharmacological and lentivirus-mediated gene transfer study

scientific article

Effects of 1-week sacral nerve stimulation on the rectal intestinal epithelial barrier and neuromuscular transmission in a porcine model

article

Effects of chondroitin and glucosamine sulfate in a dietary bar formulation on inflammation, interleukin-1beta, matrix metalloprotease-9, and cartilage damage in arthritis

scientific article published in April 2005

Endogenous analgesia mediated by CD4(+) T lymphocytes is dependent on enkephalins in mice

scientific article published on June 2016

Endogenous opioid-mediated analgesia is dependent on adaptive T cell response in mice

scientific article

Endogenous opioid-mediated antinociception in cholestatic mice is peripherally, not centrally, mediated

scientific article published on 27 December 2005

Endogenous regulation of visceral pain via production of opioids by colitogenic CD4(+) T cells in mice

scientific article

Engineering lactococci and lactobacilli for human health

scientific article published on June 2013

Enhanced anti-inflammatory effects of a nitric oxide–releasing derivative of mesalamine in rats

scientific article published on 01 September 1999

Epithelial expression and function of trypsin-3 in irritable bowel syndrome

scientific article

Evidence for the presence of functional protease activated receptor 4 (PAR4) in the rat colon

scientific journal article

Expression and secretion of lipocortin 1 in gut inflammation are not regulated by pituitary-adrenal axis

scientific article published on 01 August 1997

F16357, a novel protease-activated receptor 1 antagonist, improves urodynamic parameters in a rat model of interstitial cystitis

scientific article published on 25 April 2016

FAK alternative splice mRNA variants expression pattern in colorectal cancer

scientific article published on 14 February 2019

Focal adhesion kinase splice variants maintain primitive acute myeloid leukemia cells through altered Wnt signaling.

scientific article

Food-Grade Bacteria Expressing Elafin Protect Against Inflammation and Restore Colon Homeostasis

scientific article published on 01 October 2012

Formyl Peptide Receptor 2 Plays a Deleterious Role During Influenza A Virus Infections

scientific article published on 30 March 2016

Functional Proteomic Profiling of Secreted Serine Proteases in Health and Inflammatory Bowel Disease.

scientific article published on 18 May 2018

Functional characterization and expression analysis of the proteinase-activated receptor-2 in human cutaneous mast cells

scientific article published on April 2006

Immune conditions associated with CD4+ T effector-induced opioid release and analgesia

scientific article published on 19 December 2011

Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2

scientific article

Inhibition of both cyclooxygenase (COX)-1 and COX-2 is required for NSAID-induced erosion formation

Inhibition of neurogenic inflammation by the Amazonian herbal medicine sangre de grado

scientific article

Inhibition of sensory afferents activation and visceral pain by a brominated algal diterpene.

scientific article

Insulin modulates protease-activated receptor 2 signaling: implications for the innate immune response.

scientific article published on 29 January 2010

Intrathecal administration of proteinase-activated receptor-2 agonists produces hyperalgesia by exciting the cell bodies of primary sensory neurons

scientific article published on 5 October 2007

Involvement of interleukin-1, prostaglandins and mast cells in rectal distension-induced colonic water secretion in rats

scientific article published in January 1998

Kallikrein-mediated activation of PARs in inflammation and nociception

Kallikrein-mediated cell signalling: targeting proteinase-activated receptors (PARs).

scientific article published on June 2006

LC-MS/MS method for rapid and concomitant quantification of pro-inflammatory and pro-resolving polyunsaturated fatty acid metabolites

scientific article published on 15 June 2013

MP72-19 IMMUNOTHERAPEUTIC STRATEGY TO TREAT BLADDER PAINFUL SYNDROME IN A CHRONIC RAT MODEL

Mechanisms behind the anti-inflammatory actions of insulin

scientific article published on January 2011

Mechanisms underlying the nociceptive and inflammatory responses induced by trypsin in the mouse paw

article

Mesalazine (5-aminosalicylic acid) alters faecal bacterial profiles, but not mucosal proteolytic activity in diarrhoea-predominant irritable bowel syndrome

scientific article

Mobilization of CD4+ T lymphocytes in inflamed mucosa reduces pain in colitis mice: toward a vaccinal strategy to alleviate inflammatory visceral pain.

scientific article

Modifying the protease, antiprotease pattern by elafin overexpression protects mice from colitis

scientific article published in January 2011

Modulation of protease activated receptor 1 influences human metapneumovirus disease severity in a mouse model

scientific article

Modulation of visceral pain and inflammation by protease-activated receptors

scientific article published on 29 March 2004

Mucosal targeting of therapeutic molecules using genetically modified lactic acid bacteria: an update

scientific article published on 16 May 2013

Multi-hit early life adversity affects gut microbiota, brain and behavior in a sex-dependent manner

scientific article published on 11 March 2019

NSAID-induced gastric damage in rats: Requirement for inhibition of both cyclooxygenase 1 and 2

scientific article published on 01 September 2000

Neonatal immune challenge alters nociception in the adult rat.

scientific article published on 16 November 2005

Neuroimmune signalling in the gut - mediators linked to disorders?

scientific article published in July 2006

Neurons and Glia in the Enteric Nervous System and Epithelial Barrier Function

Neutrophil-mediated activation of epithelial protease-activated receptors-1 and -2 regulates barrier function and transepithelial migration

scientific article published on October 2008

Neutrophils and the kallikrein-kinin system in proteinase-activated receptor 4-mediated inflammation in rodents

scientific article published on November 2005

New neostigmine-based behavioral mouse model of abdominal pain

scientific article published on 01 January 2012

Novel role of the serine protease inhibitor elafin in gluten-related disorders

scientific article

P100 Intestinal epithelial cells under endoplasmic reticulum stress boosts serine proteolytic activity and modulates barrier function

PAR(2) and temporomandibular joint inflammation in the rat.

scientific article published on 22 July 2010

PAR2 activation alters colonic paracellular permeability in mice via IFN-gamma-dependent and -independent pathways

scientific article

PAR2-dependent activation of GSK3β regulates the survival of colon stem/progenitor cells.

scientific article published on 16 June 2016

Polyunsaturated fatty acid metabolism signature in ischemia differs from reperfusion in mouse intestine

scientific article

Postinflammatory visceral sensitivity and pain mechanisms

scientific article published on May 2008

Potentiation of TRPV4 signalling by histamine and serotonin: an important mechanism for visceral hypersensitivity

scientific article published in April 2010

Presence of commensal house dust mite allergen in human gastrointestinal tract: a potential contributor to intestinal barrier dysfunction

scientific article published on 8 December 2015

Pro- and anti-inflammatory actions of thrombin: a distinct role for proteinase-activated receptor-1 (PAR1).

scientific article published on March 1999

Proinflammatory role of proteinase-activated receptor-2 in humans and mice during cutaneous inflammation in vivo

scientific article published in October 2003

Protease Signaling to G Protein-Coupled Receptors: Implications for Inflammation and Pain

scientific article published on 01 January 2008

Protease inhibition as new therapeutic strategy for GI diseases

scientific article

Protease-Activated Receptor 1 is Implicated in Irritable Bowel Syndrome Mediators-Induced Signalling to Thoracic Human Sensory Neurons

scientific article published on 15 March 2018

Protease-Activated Receptor 2 contributes to Toxoplasma gondii-mediated gut inflammation.

scientific article published on 7 September 2017

Protease-activated receptor 2 sensitizes TRPV1 by protein kinase Cepsilon- and A-dependent mechanisms in rats and mice

scientific article published on 22 June 2006

Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia.

scientific article published in May 2004

Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice

scientific article published on 23 November 2006

Protease-activated receptor-2 (PAR(2)) in human periodontitis

scientific article published on 8 June 2010

Protease-activated receptor-2 activation: a major actor in intestinal inflammation.

scientific article published on 6 May 2008

Protease-activated receptor-2 activation: a major role in the pathogenesis of Porphyromonas gingivalis infection

scientific article published on April 2006

Protease-activated receptor-4 (PAR 4): a role as inhibitor of visceral pain and hypersensitivity.

scientific article published on 20 April 2009

Protease-activated receptor-4: a novel mechanism of inflammatory pain modulation

scientific journal article

Protease-activated receptors and inflammatory hyperalgesia

scientific article

Protease-activated receptors as drug targets in inflammation and pain

scientific article published on 28 May 2009

Proteases and protease-activated receptors (PARs): novel signals for pain.

scientific article

Protectin D1n-3 DPA and resolvin D5n-3 DPA are effectors of intestinal protection

scientific article

Protective effect of proteinase-activated receptor 2 activation on motility impairment and tissue damage induced by intestinal ischemia/reperfusion in rodents

scientific article

Protective effects of n-6 fatty acids-enriched diet on intestinal ischaemia/reperfusion injury involve lipoxin A4 and its receptor.

scientific article published on 15 December 2014

Protective role for protease-activated receptor-2 against influenza virus pathogenesis via an IFN-gamma-dependent pathway

scientific article

Proteinase-Activated Receptor-2 Induction by Neuroinflammation Prevents Neuronal Death during HIV Infection

article

Proteinase-Activated Receptor-4 is implicated in the pathogenesis of Dextran Sodium Sulfate colitis

Proteinase-activated recaptor-2 (PAR-2) activation produces delayed rectal hyperalgesia in awake rats

Proteinase-activated receptor 1 activation induces epithelial apoptosis and increases intestinal permeability

scientific article

Proteinase-activated receptor 2 (PAR2)-activating peptides: identification of a receptor distinct from PAR2 that regulates intestinal transport

scientific article published on June 1998

Proteinase-activated receptor 2 activation modulates guinea-pig mesenteric lymphatic vessel pacemaker potential and contractile activity

scientific article

Proteinase-activated receptor 2 is an anti-inflammatory signal for colonic lamina propria lymphocytes in a mouse model of colitis

scientific article

Proteinase-activated receptor 2 modulates neuroinflammation in experimental autoimmune encephalomyelitis and multiple sclerosis

scientific article

Proteinase-activated receptor-1 agonists attenuate nociception in response to noxious stimuli

scientific article published in March 2002

Proteinase-activated receptor-1 agonists attenuate visceral pain

Proteinase-activated receptor-1 is an anti-inflammatory signal for colitis mediated by a type 2 immune response

scientific article published in September 2005

Proteinase-activated receptor-2 (PAR2) agonist causes periodontitis in rats

scientific article published in February 2005

Proteinase-activated receptor-2 (PAR2): a tumor suppressor in skin carcinogenesis

scientific article published on 3 May 2007

Proteinase-activated receptor-2 and hyperalgesia: A novel pain pathway

scientific article published on 01 July 2001

Proteinase-activated receptor-2 exerts protective and pathogenic cell type-specific effects in Alzheimer's disease

scientific article

Proteinase-activated receptor-2-induced colonic inflammation in mice: possible involvement of afferent neurons, nitric oxide, and paracellular permeability

scientific article published in April 2003

Proteinase-activated receptor-4: evaluation of tethered ligand-derived peptides as probes for receptor function and as inflammatory agonists in vivo

scientific article published on 27 September 2004

Proteinase-activated receptors (PARs) in infection and inflammation in the gut.

scientific article published on 20 January 2008

Proteinase-activated receptors (PARs): crossroads between innate immunity and coagulation

scientific article published on 13 June 2006

Proteinase-activated receptors and nociceptive pathways

Proteinase-activated receptors in the nervous system

scientific article published on December 2003

Proteinase-activated receptors: novel signals for peripheral nerves.

scientific article

Proteinase-activated receptors: transducers of proteinase-mediated signaling in inflammation and immune response.

scientific article

Proteinase-mediated cell signalling: targeting proteinase-activated receptors (PARs) by kallikreins and more

scientific article published on June 2006

Proteinases and proteinase-activated receptor 2: a possible role to promote visceral hyperalgesia in rats

scientific article published in April 2002

Quantification and Potential Functions of Endogenous Agonists of Transient Receptor Potential Channels in Patients With Irritable Bowel Syndrome

scientific article published on 22 April 2015

Relevance of the cyclophosphamide-induced cystitis model for pharmacological studies targeting inflammation and pain of the bladder

scientific article published on 26 March 2013

Reply

scientific article published on 29 January 2016

Revisiting the Hallmarks of Aging to Identify Markers of Biological Age

scientific article published on 01 January 2020

Role for protease activity in visceral pain in irritable bowel syndrome

scientific article

Role of proteinase-activated receptor-2 in anti-bacterial and immunomodulatory effects of interferon-γ on human neutrophils and monocytes

scientific article

Role of transient receptor potential vanilloid 4 in rat joint inflammation

scientific article published on 19 December 2011

S3-4 H2S targets transient receptor potential receptors to relieve from inflammation and pain

Sacral nerve stimulation enhances early intestinal mucosal repair following mucosal injury in a pig model.

scientific article

Selective cyclo-oxygenase-2 inhibition with celecoxib elevates blood pressure and promotes leukocyte adherence

scientific article

Serine protease inhibition reduces post-ischemic granulocyte recruitment in mouse intestine

scientific article published on 7 November 2011

Serine protease inhibitors protect better than IL-10 and TGF-β anti-inflammatory cytokines against mouse colitis when delivered by recombinant lactococci

scientific article published on 26 February 2015

Sex differences in the GSK3β-mediated survival of adherent leukemic progenitors

scientific article published on 4 July 2011

Sexual dimorphism in PAR2-dependent regulation of primitive colonic cells

scientific article published on 06 September 2019

Su1947 Mesotrypsin Evokes PAR2 Dependent Excitabilty of Nociceptive Dorsal Root Ganglia (DRG) Neurons

Su1949 Protease-Activated Receptors Are Expressed and Can Be Activated in Human Sensory Neurons

Sustainable Positive Response to Sirolimus in Juvenile Polyposis of Infancy

scientific article published on 01 February 2019

TRPM8 activation attenuates inflammatory responses in mouse models of colitis

scientific article published on 17 April 2013

TRPV1 sensitization mediates postinflammatory visceral pain following acute colitis.

scientific article published on 28 May 2015

TRPV4: new therapeutic target for inflammatory bowel diseases

scientific article published on 16 January 2014

Targeting fatty acid amide hydrolase and transient receptor potential vanilloid-1 simultaneously to modulate colonic motility and visceral sensation in the mouse: A pharmacological intervention with N-arachidonoyl-serotonin (AA-5-HT).

scientific article

The C-terminus of murine S100A9 protein inhibits hyperalgesia induced by the agonist peptide of protease-activated receptor 2 (PAR2).

scientific article published on 11 September 2006

The Canadian Association of Gastroenteroloy - Are You a Member Yet?

article

The Enteric Nervous System in Inflammation and Pain: The Role of Proteinase-Activated Receptors ⬇️

scientific article published on October 1, 2003

The Intestinal Microenvironment and Functional Gastrointestinal Disorders

scientific article published on 18 February 2016

The arachidonic acid metabolite 11β-ProstaglandinF2α controls intestinal epithelial healing: deficiency in patients with Crohn's disease

scientific article published on 3 May 2016

The inflammatory response

Thrombin modifies growth, proliferation and apoptosis of human colon organoids: a protease-activated receptor 1- and protease-activated receptor 4-dependent mechanism

scientific article published on 07 August 2018

Thrombin receptor: An endogenous inhibitor of inflammatory pain, activating opioid pathways.

scientific article

Transient receptor potential vanilloid 4 activated inflammatory signals by intestinal epithelial cells and colitis in mice

scientific article published on October 2010

Transient receptor potential vanilloid-4 has a major role in visceral hypersensitivity symptoms

scientific article published on 10 May 2008

Triggering of proteinase-activated receptor 4 leads to joint pain and inflammation in mice

scientific article published in March 2009

Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia

scientific article

Up-regulation of proteinase-activated receptor 1 expression in astrocytes during HIV encephalitis

scientific article published in March 2003

Using murine colitis models to analyze probiotics-host interactions.

scientific article published on August 2017

Visceral afferents: what role in post-inflammatory pain?

scientific article published on 09 August 2009

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