Search filters

List of works by Brian H Johnston

A random-walk model for retardation of interacting species during gel electrophoresis: implications for gel-shift assays

scientific article

Capture in the gel: intermoleculare triplex formation during gel electrophoresis

scientific article published on 01 October 1996

Characterization of the photoreaction between DNA and aminomethyl-trimethylpsoralen using absorption and fluorescence spectroscopy

scientific article published on 01 June 1981

Chemical probing of the B-Z transition in negatively supercoiled DNA

scientific article published on 01 August 1988

Complement-stabilized D-loop. RecA-catalyzed stable pairing of linear DNA molecules at internal sites.

scientific article

Complete, gene-specific siRNA libraries: production and expression in mammalian cells

scientific article published in May 2005

Delivery and inhibition of reporter genes by small interfering RNAs in a mouse skin model

scientific article published on 24 May 2007

Denaturation and association of DNA sequences by certain polypropylene surfaces.

scientific article published in September 1997

Design and chemical modification of synthetic short shRNAs as potent RNAi triggers

Effects of chemical modification on the potency, serum stability, and immunostimulatory properties of short shRNAs

scientific article

Formulated minimal-length synthetic small hairpin RNAs are potent inhibitors of hepatitis C virus in mice with humanized livers

scientific article

Generation and detection of Z-DNA.

scientific article

Hairpin ribozyme-antisense RNA constructs can act as molecular Lassos.

scientific article published on 25 October 2008

Hairpin ribozyme-catalyzed ligation in water-alcohol solutions.

scientific article published in December 2005

Hydroxylamine and methoxylamine as probes of DNA structure

scientific article published on January 1, 1992

Inhibition of Hepatitis C IRES-Mediated Gene Expression by Small Hairpin RNAs in Human Hepatocytes and Mice

article

Inhibition of hepatitis C IRES-mediated gene expression by 8-17 deoxyribozymes in human tissue culture cells.

scientific article published in September 2006

Inhibition of hepatitis C virus in chimeric mice by short synthetic hairpin RNAs: sequence analysis of surviving virus shows added selective pressure of combination therapy.

scientific article published on 29 January 2014

Intramolecular triple-helix formation at (PunPyn).(PunPyn) tracts: recognition of alternate strands via Pu.PuPy and Py.PuPy base triplets.

scientific article

Kinetics of formation of deoxyribonucleic acid cross-links by 4'-(aminomethyl)-4,5',8-trimethylpsoralen.

scientific article published on February 1981

Ligation activity of fragmented ribozymes in frozen solution: implications for the RNA world

scientific article

Ligation of the hairpin ribozyme in cis induced by freezing and dehydration

scientific article

Mapping adducts of DNA structural probes using transcription and primer extension approaches

scientific article published on January 1, 1992

Minimal-length Synthetic shRNAs Formulated with Lipid Nanoparticles are Potent Inhibitors of Hepatitis C Virus IRES-linked Gene Expression in Mice

scientific article

Minimal-length short hairpin RNAs: the relationship of structure and RNAi activity

scientific article

Oligonucleotide-directed triple helix formation at adjacent oligopurine and oligopyrimidine DNA tracts by alternate strand recognition

scientific article published on October 25, 1992

Polypropylene tube surfaces may induce denaturation and multimerization of DNA

scientific article published on 01 January 1996

RNA catalysis in frozen solutions

scientific article published on 01 May 2005

RNA interference from multimeric shRNAs generated by rolling circle transcription

scientific article published on January 2006

RNA interference-mediated inhibition of Semliki Forest virus replication in mammalian cells.

scientific article published on January 2007

ROLL: a method of preparation of gene-specific oligonucleotide libraries.

scientific article

Right- and left-loop short shRNAs have distinct and unusual mechanisms of gene silencing

scientific article

Sequence limitations of triple helix formation by alternate-strand recognition.

scientific article

Site-specific cleavage of the transactivation response site of human immunodeficiency virus RNA with a tat-based chemical nuclease

scientific article published on April 15, 1992

Small hairpin RNAs efficiently inhibit hepatitis C IRES-mediated gene expression in human tissue culture cells and a mouse model

scientific article published on September 2005

Stability study of unmodified siRNA and relevance to clinical use.

scientific article

Stochastic distribution of a short region of Z-DNA within a long repeated sequence in negatively supercoiled plasmids

scientific article published on 01 April 1988

The RNA world on ice: a new scenario for the emergence of RNA information

scientific article

The S1-sensitive form of d(C-T)n.d(A-G)n: chemical evidence for a three-stranded structure in plasmids

scientific article

miR-ID: a novel, circularization-based platform for detection of microRNAs

scientific article

shRNAs targeting hepatitis C: effects of sequence and structural features, and comparision with siRNA.

scientific article