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List of works by Dubrez Laurence

BCR-ABL delays apoptosis upstream of procaspase-3 activation

scientific article published on 01 April 1998

Bcl-2 proteins: targets and tools for chemosensitisation of tumor cells

scientific article

Caffeine sensitizes human H358 cell line to p53-mediated apoptosis by inducing mitochondrial translocation and conformational change of BAX protein.

scientific article

Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis

scientific article

Cellular inhibitor of apoptosis protein-1 (cIAP1) can regulate E2F1 transcription factor-mediated control of cyclin transcription

scientific article

Cellular pharmacology of azatoxins (topoisomerase-II and tubulin inhibitors) in P-glycoprotein-positive and -negative cell lines.

scientific article

DNA damage and S phase-dependent E2F1 stabilization requires the cIAP1 E3-ubiquitin ligase and is associated with K63-poly-ubiquitination on lysine 161/164 residues.

scientific article published on 25 May 2017

E2F1 binds to the peptide-binding groove within the BIR3 domain of cIAP1 and requires cIAP1 for chromatin binding

scientific article published in PLoS ONE

E2F1 interacts with BCL-xL and regulates its subcellular localization dynamics to trigger cell death.

scientific article published on 12 December 2017

HSP110 translocates to the nucleus upon genotoxic chemotherapy and promotes DNA repair in colorectal cancer cells

scientific article published on 12 December 2018

Heat-shock proteins: chaperoning DNA repair

scientific article published on 20 September 2019

IAP proteins as targets for drug development in oncology

scientific article published on 16 September 2013

IAP-Mediated Protein Ubiquitination in Regulating Cell Signaling

scientific article published on 30 April 2020

IAPs and cell migration.

scientific article published on 10 March 2015

IAPs: Mediators of Oncogenesis and Targets for Anticancer Therapy.

scientific article published in January 2016

IAPs: a central element in the NF-κB activating signaling pathway

scientific article

IAPs: more than just inhibitors of apoptosis proteins

scientific article

Increased gadd153 messenger RNA level is associated with apoptosis in human leukemic cells treated with etoposide

scientific article published on 01 February 1997

Inhibition of apoptosis by amphiregulin via an insulin-like growth factor-1 receptor-dependent pathway in non-small cell lung cancer cell lines

scientific article

Inhibition of apoptosis by amphiregulin via an insulin-like growth factor-1 receptor-dependent pathway in non-small cell lung cancer cell lines

scientific article published on 01 December 2003

Mitochondria as a target for inducing death of malignant hematopoietic cells.

scientific article

Regulation of Apoptosis by Inhibitors of Apoptosis (IAPs)

scientific article published on 14 March 2013

Regulation of E2F1 Transcription Factor by Ubiquitin Conjugation.

scientific article published on 19 October 2017

Selecting the first chemical molecule inhibitor of HSP110 for colorectal cancer therapy

scientific article published on 08 May 2019

Serpin B1 defect and increased apoptosis of neutrophils in Cohen syndrome neutropenia

scientific article published on 07 March 2019

Specific involvement of caspases in the differentiation of monocytes into macrophages

scientific article

The Inhibitor of Apoptosis (IAPs) in Adaptive Response to Cellular Stress

scientific article published on 10 October 2012

The role of apoptosis in the pathogenesis and treatment of diseases.

scientific article published on June 1996

The role of cell cycle regulation and apoptosis triggering in determining the sensitivity of leukemic cells to topoisomerase I and II inhibitors

scientific article published on June 1, 1995

Towards the elaboration of new gold-based optical theranostics

scientific article

Upregulation of CASP genes in human tumor cells undergoing etoposide-induced apoptosis ⬇️

scientific article published on June 4, 1998

[Apoptosis of human leukemic cells induced by topoisomerase I and II inhibitors]

scientific article published on 01 March 1996

[IAP and Rho finally connected]

scientific article published on 31 March 2014

[Unexpected role of IAPs in transcriptional regulation]

scientific article published on 22 May 2019

cIAP1 regulates TNF-mediated cdc42 activation and filopodia formation.

scientific article

cIAP1-dependent TRAF2 degradation regulates the differentiation of monocytes into macrophages and their response to CD40 ligand

scientific article

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