List of works - Francesco Ciccia

A 2-year comparative open label randomized study of efficacy and safety of etanercept and infliximab in patients with ankylosing spondylitis

scientific article published on 23 October 2009

Activated IL-22 pathway occurs in the muscle tissues of patients with polymyositis or dermatomyositis and is correlated with disease activity

scientific article published on 05 March 2014

Adult-onset Still's disease: an Italian multicentre retrospective observational study of manifestations and treatments in 245 patients

scientific article

Anti-tumour necrosis factor alpha monoclonal antibody therapy for recalcitrant cerebral vasculitis in a patient with Behçet's syndrome.

scientific article published on March 2003

Arterial stiffness indexes and serum cytokine levels in seronegative spondyloarthritis: relationships between stiffness markers and metabolic and immunoinflammatory variables

scientific article published on 14 July 2015

Autophagy in the pathogenesis of ankylosing spondylitis

scientific article published on 13 April 2016

Brief Report: Intestinal Dysbiosis in Ankylosing Spondylitis

scientific article published on 21 November 2014

Difference in the expression of IL-9 and IL-17 correlates with different histological pattern of vascular wall injury in giant cell arteritis

scientific article published on 09 April 2015

Disease-associated polymorphisms in ERAP1 do not alter endoplasmic reticulum stress in patients with ankylosing spondylitis

article

Early disease and low baseline damage predict response to belimumab in patients with systemic lupus erythematosus

scientific article published on 10 April 2020

Ectopic expression of CXCL13, BAFF, APRIL and LT-β is associated with artery tertiary lymphoid organs in giant cell arteritis.

scientific article published on 20 April 2016

Endothelial progenitor cells: Are they displaying a function in autoimmune disorders?

scientific article published on 3 May 2016

Exosomes as intercellular signaling organelles involved in health and disease: basic science and clinical applications.

scientific article published on 6 March 2013

Expansion of intestinal CD4+CD25(high) Treg cells in patients with ankylosing spondylitis: a putative role for interleukin-10 in preventing intestinal Th17 response.

scientific article

Expression of interleukin-32 in the inflamed arteries of patients with giant cell arteritis.

scientific article

Gut-derived CD8+ tissue-resident memory T cells are expanded in the peripheral blood and synovia of SpA patients

scientific article published on 18 October 2019

H-ferritin and CD68(+) /H-ferritin(+) monocytes/macrophages are increased in the skin of adult-onset Still's disease patients and correlate with the multi-visceral involvement of the disease.

scientific article published on 18 June 2016

Humoral and cell mediated immune response to cow's milk proteins in Behçet's disease

scientific article

IL-1β at the crossroad between rheumatoid arthritis and type 2 diabetes: may we kill two birds with one stone?

scientific article

IL-33 is overexpressed in the inflamed arteries of patients with giant cell arteritis.

scientific article

IL-34 is overexpressed in the inflamed salivary glands of patients with Sjogren's syndrome and is associated with the local expansion of pro-inflammatory CD14(bright)CD16+ monocytes

scientific article published on 07 February 2013

IVIG in APS pregnancy

scientific article published in January 2004

Increased expression of interleukin-22 in patients with giant cell arteritis.

scientific article

Increased expression of interleukin-32 in the inflamed ileum of ankylosing spondylitis patients

scientific article published on 30 July 2012

Increased level of H-ferritin and its imbalance with L-ferritin, in bone marrow and liver of patients with adult onset Still's disease, developing macrophage activation syndrome, correlate with the severity of the disease.

scientific article

Interleukin (IL)-22 receptor 1 is over-expressed in primary Sjogren's syndrome and Sjögren-associated non-Hodgkin lymphomas and is regulated by IL-18.

scientific article

Interleukin-22 and interleukin-22-producing NKp44+ natural killer cells in subclinical gut inflammation in ankylosing spondylitis.

scientific article published on 27 December 2011

Interleukin-36α axis is modulated in patients with primary Sjögren's syndrome.

scientific article published on 3 June 2015

Interleukin-9 Overexpression and Th9 Polarization Characterize the Inflamed Gut, the Synovial Tissue, and the Peripheral Blood of Patients With Psoriatic Arthritis

scientific article published on 01 August 2016

Interleukin-9 and T helper type 9 cells in rheumatic diseases.

scientific article published on 9 May 2016

Intestinal dysbiosis and innate immune responses in axial spondyloarthritis

scientific article

Is minor salivary gland biopsy more than a diagnostic tool in primary Sjo¨gren׳s syndrome? Association between clinical, histopathological, and molecular features: A retrospective study

scientific article published on 15 May 2014

Jejunoileal bypass as the main procedure in the onset of immune-related conditions: the model of BADAS.

scientific article published on May 2013

Long-term anti-tumour necrosis factor therapy reverses the progression of carotid intima-media thickness in female patients with active rheumatoid arthritis.

scientific article published in December 2009

Macrophage phenotype in the subclinical gut inflammation of patients with ankylosing spondylitis

scientific article

Mesenchymal stromal cells and rheumatic diseases: new tools from pathogenesis to regenerative therapies.

scientific article

Monocytes from patients with rheumatoid arthritis and type 2 diabetes mellitus display an increased production of interleukin (IL)-1β via the nucleotide-binding domain and leucine-rich repeat containing family pyrin 3(NLRP3)-inflammasome activation:

scientific article published on 10 June 2015

New insights into the pathogenesis of giant cell arteritis

scientific article published on 4 May 2017

Non-conventional forms of HLA-B27 are expressed in spondyloarthritis joints and gut tissue.

scientific article published on 29 March 2016

One year study of efficacy and safety of infliximab in the treatment of patients with ocular and neurological Behçet's disease refractory to standard immunosuppressive drugs

scientific article published on 27 October 2009

Over-expression of paneth cell-derived anti-microbial peptides in the gut of patients with ankylosing spondylitis and subclinical intestinal inflammation

scientific article published on 05 August 2010

Overexpression of interleukin-23, but not interleukin-17, as an immunologic signature of subclinical intestinal inflammation in ankylosing spondylitis

scientific article published on 01 April 2009

Perivascular Cells in Diffuse Cutaneous Systemic Sclerosis Overexpress Activated ADAM12 and Are Involved in Myofibroblast Transdifferentiation and Development of Fibrosis.

scientific article published in June 2016

Phenotype and functional changes of Vgamma9/Vdelta2 T lymphocytes in Behçet's disease and the effect of infliximab on Vgamma9/Vdelta2 T cell expansion, activation and cytotoxicity.

scientific article

Potential involvement of IL-22 and IL-22-producing cells in the inflamed salivary glands of patients with Sjogren's syndrome.

scientific article

Potential involvement of IL-9 and Th9 cells in the pathogenesis of rheumatoid arthritis

scientific article published on 15 July 2015

Prescribing motivations and patients' characteristics related to the use of biologic drugs in adult-onset Still's disease: analysis of a multicentre "real-life" cohort

scientific article published on 01 July 2019

Prevalence of headache in patients with Behçet's disease without overt neurological involvement

scientific article published in March 2003

Randomized study of subcutaneous low molecular weight heparin plus aspirin versus intravenous immunoglobulin in the treatment of recurrent fetal loss associated with antiphospholipid antibodies

scientific article (publication date: March 2003)

Response to: 'IL-23 expression and activation of autophagy in synovium and PBMCs of HLA-B27 positive patients with ankylosing spondylitis' by Neerinckx et al

scientific article published on 20 August 2014

Rituximab in primary Sjögren's syndrome: a ten-year journey.

scientific article

Rituximab modulates IL-17 expression in the salivary glands of patients with primary Sjögren’s syndrome

scientific article published on 06 March 2014

Rituximab modulates the expression of IL-22 in the salivary glands of patients with primary Sjogren's syndrome

scientific article published on 21 December 2012

Safety and efficacy of intra-articular anti-tumor necrosis factor α agents compared to corticosteroids in a treat-to-target strategy in patients with inflammatory arthritis and monoarthritis flare

scientific article published on 18 December 2015

Subclinical gut inflammation in ankylosing spondylitis

scientific article published in January 2016

The CD68(+)/H-ferritin(+) cells colonize the lymph nodes of the patients with adult onset Still's disease and are associated with increased extracellular level of H-ferritin in the same tissue: correlation with disease severity and implication for p

scientific article published on 5 November 2015

The in vitro addition of methotrexate and/or methylprednisolone determines peripheral reduction in Th17 and expansion of conventional Treg and of IL-10 producing Th17 lymphocytes in patients with early rheumatoid arthritis

scientific article published on 03 May 2014

The role of innate and lymphoid IL-22-producing cells in the immunopathology of primary Sjögren's syndrome.

scientific article published on 04 February 2014

Tocilizumab therapy for unresponsive pulmonary arterial hypertension in a patient with Takayasu arteritis

scientific article published on 01 January 2016

Type 3 innate lymphoid cells producing IL-17 and IL-22 are expanded in the gut, in the peripheral blood, synovial fluid and bone marrow of patients with ankylosing spondylitis.

scientific article published on 22 April 2015

List of works by Francesco Ciccia

A 2-year comparative open label randomized study of efficacy and safety of etanercept and infliximab in patients with ankylosing spondylitis

Activated IL-22 pathway occurs in the muscle tissues of patients with polymyositis or dermatomyositis and is correlated with disease activity

Adult-onset Still's disease: an Italian multicentre retrospective observational study of manifestations and treatments in 245 patients

Anti-tumour necrosis factor alpha monoclonal antibody therapy for recalcitrant cerebral vasculitis in a patient with Behçet's syndrome.

Arterial stiffness indexes and serum cytokine levels in seronegative spondyloarthritis: relationships between stiffness markers and metabolic and immunoinflammatory variables

Autophagy in the pathogenesis of ankylosing spondylitis

Brief Report: Intestinal Dysbiosis in Ankylosing Spondylitis

Difference in the expression of IL-9 and IL-17 correlates with different histological pattern of vascular wall injury in giant cell arteritis

Disease-associated polymorphisms in ERAP1 do not alter endoplasmic reticulum stress in patients with ankylosing spondylitis

Early disease and low baseline damage predict response to belimumab in patients with systemic lupus erythematosus

Ectopic expression of CXCL13, BAFF, APRIL and LT-β is associated with artery tertiary lymphoid organs in giant cell arteritis.

Endothelial progenitor cells: Are they displaying a function in autoimmune disorders?

Exosomes as intercellular signaling organelles involved in health and disease: basic science and clinical applications.

Expansion of intestinal CD4+CD25(high) Treg cells in patients with ankylosing spondylitis: a putative role for interleukin-10 in preventing intestinal Th17 response.

Expression of interleukin-32 in the inflamed arteries of patients with giant cell arteritis.

Gut-derived CD8+ tissue-resident memory T cells are expanded in the peripheral blood and synovia of SpA patients

H-ferritin and CD68(+) /H-ferritin(+) monocytes/macrophages are increased in the skin of adult-onset Still's disease patients and correlate with the multi-visceral involvement of the disease.

Humoral and cell mediated immune response to cow's milk proteins in Behçet's disease

IL-1β at the crossroad between rheumatoid arthritis and type 2 diabetes: may we kill two birds with one stone?

IL-33 is overexpressed in the inflamed arteries of patients with giant cell arteritis.

IL-34 is overexpressed in the inflamed salivary glands of patients with Sjogren's syndrome and is associated with the local expansion of pro-inflammatory CD14(bright)CD16+ monocytes

IVIG in APS pregnancy

Increased expression of interleukin-22 in patients with giant cell arteritis.

Increased expression of interleukin-32 in the inflamed ileum of ankylosing spondylitis patients

Increased level of H-ferritin and its imbalance with L-ferritin, in bone marrow and liver of patients with adult onset Still's disease, developing macrophage activation syndrome, correlate with the severity of the disease.

Interleukin (IL)-22 receptor 1 is over-expressed in primary Sjogren's syndrome and Sjögren-associated non-Hodgkin lymphomas and is regulated by IL-18.

Interleukin-22 and interleukin-22-producing NKp44+ natural killer cells in subclinical gut inflammation in ankylosing spondylitis.

Interleukin-36α axis is modulated in patients with primary Sjögren's syndrome.

Interleukin-9 Overexpression and Th9 Polarization Characterize the Inflamed Gut, the Synovial Tissue, and the Peripheral Blood of Patients With Psoriatic Arthritis

Interleukin-9 and T helper type 9 cells in rheumatic diseases.

Intestinal dysbiosis and innate immune responses in axial spondyloarthritis

Is minor salivary gland biopsy more than a diagnostic tool in primary Sjo¨gren׳s syndrome? Association between clinical, histopathological, and molecular features: A retrospective study

Jejunoileal bypass as the main procedure in the onset of immune-related conditions: the model of BADAS.

Long-term anti-tumour necrosis factor therapy reverses the progression of carotid intima-media thickness in female patients with active rheumatoid arthritis.

Macrophage phenotype in the subclinical gut inflammation of patients with ankylosing spondylitis

Mesenchymal stromal cells and rheumatic diseases: new tools from pathogenesis to regenerative therapies.

Monocytes from patients with rheumatoid arthritis and type 2 diabetes mellitus display an increased production of interleukin (IL)-1β via the nucleotide-binding domain and leucine-rich repeat containing family pyrin 3(NLRP3)-inflammasome activation:

New insights into the pathogenesis of giant cell arteritis

Non-conventional forms of HLA-B27 are expressed in spondyloarthritis joints and gut tissue.

One year study of efficacy and safety of infliximab in the treatment of patients with ocular and neurological Behçet's disease refractory to standard immunosuppressive drugs

Over-expression of paneth cell-derived anti-microbial peptides in the gut of patients with ankylosing spondylitis and subclinical intestinal inflammation

Overexpression of interleukin-23, but not interleukin-17, as an immunologic signature of subclinical intestinal inflammation in ankylosing spondylitis

Perivascular Cells in Diffuse Cutaneous Systemic Sclerosis Overexpress Activated ADAM12 and Are Involved in Myofibroblast Transdifferentiation and Development of Fibrosis.

Phenotype and functional changes of Vgamma9/Vdelta2 T lymphocytes in Behçet's disease and the effect of infliximab on Vgamma9/Vdelta2 T cell expansion, activation and cytotoxicity.

Potential involvement of IL-22 and IL-22-producing cells in the inflamed salivary glands of patients with Sjogren's syndrome.

Potential involvement of IL-9 and Th9 cells in the pathogenesis of rheumatoid arthritis

Prescribing motivations and patients' characteristics related to the use of biologic drugs in adult-onset Still's disease: analysis of a multicentre "real-life" cohort

Prevalence of headache in patients with Behçet's disease without overt neurological involvement

Randomized study of subcutaneous low molecular weight heparin plus aspirin versus intravenous immunoglobulin in the treatment of recurrent fetal loss associated with antiphospholipid antibodies

Response to: 'IL-23 expression and activation of autophagy in synovium and PBMCs of HLA-B27 positive patients with ankylosing spondylitis' by Neerinckx et al

Rituximab in primary Sjögren's syndrome: a ten-year journey.

Rituximab modulates IL-17 expression in the salivary glands of patients with primary Sjögren’s syndrome

Rituximab modulates the expression of IL-22 in the salivary glands of patients with primary Sjogren's syndrome

Safety and efficacy of intra-articular anti-tumor necrosis factor α agents compared to corticosteroids in a treat-to-target strategy in patients with inflammatory arthritis and monoarthritis flare

Subclinical gut inflammation in ankylosing spondylitis

The CD68(+)/H-ferritin(+) cells colonize the lymph nodes of the patients with adult onset Still's disease and are associated with increased extracellular level of H-ferritin in the same tissue: correlation with disease severity and implication for p

The in vitro addition of methotrexate and/or methylprednisolone determines peripheral reduction in Th17 and expansion of conventional Treg and of IL-10 producing Th17 lymphocytes in patients with early rheumatoid arthritis

The role of innate and lymphoid IL-22-producing cells in the immunopathology of primary Sjögren's syndrome.

Tocilizumab therapy for unresponsive pulmonary arterial hypertension in a patient with Takayasu arteritis

Type 3 innate lymphoid cells producing IL-17 and IL-22 are expanded in the gut, in the peripheral blood, synovial fluid and bone marrow of patients with ankylosing spondylitis.